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N-Glycosylation and Inflammation; the Not-So-Sweet Relation

https://doi.org/10.3389/fimmu.2022.893365

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CD22 serves as a receptor for soluble IgM

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Purification and properties of sialoadhesin, a sialic acid‐binding receptor of murine tissue macrophages.

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Sialoadhesin, a macrophage sialic acid binding receptor for haemopoietic cells with 17 immunoglobulin‐like domains.

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Regulation of sialyl-Lewis x epitope expression by TNF-α and EGF in an airway carcinoma cell line

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VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site

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Galectin-3 Modulates Th17 Responses by Regulating Dendritic Cell Cytokines

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Glycosylation of site-specific glycans of α1-acid glycoprotein and alterations in acute and chronic inflammation

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Identification of an inducible factor secreted by pancreatic cancer cell lines that stimulates the production of fucosylated haptoglobin in hepatoma cells

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TNF regulates sialyl-Lewisx and 6-sulfo-sialyl-Lewisx expression in human lung through up-regulation of ST3GAL4 transcript isoform BX

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Pathogen Recognition and Innate Immunity

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Complex N-Glycan Number and Degree of Branching Cooperate to Regulate Cell Proliferation and Differentiation

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Metabolism, Cell Surface Organization, and Disease

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The Effect of Sustained Inflammation on Hepatic Mevalonate Pathway Results in Hyperglycemia

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B cells as antigen presenting cells

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Downregulating galectin-3 inhibits proinflammatory cytokine production by human monocyte-derived dendritic cells via RNA interference

inferredcites →https://doi.org/10.1016/j.cellimm.2018.07.009openalex-snapshot

Immunoglobulin G glycosylation in aging and diseases

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TNFR1-induced NF-κB, but not ERK, p38MAPK or JNK activation, mediates TNF-induced ICAM-1 and VCAM-1 expression on endothelial cells

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Neu1 desialylation of sialyl α-2,3-linked β-galactosyl residues of TOLL-like receptor 4 is essential for receptor activation and cellular signaling

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Blockage of Core Fucosylation Reduces Cell-Surface Expression of PD-1 and Promotes Anti-tumor Immune Responses of T Cells

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Terminal sugars of Fc glycans influence antibody effector functions of IgGs

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Neutrophils come of age in chronic inflammation

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AMSC-derived exosomes alleviate lipopolysaccharide/d-galactosamine-induced acute liver failure by miR-17-mediated reduction of TXNIP/NLRP3 inflammasome activation in macrophages

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Interferon-α alters host glycosylation machinery during treated HIV infection

inferredcites →https://doi.org/10.1016/j.ejphar.2018.11.014openalex-snapshot

Sialidase activity in human pathologies

inferredcites →https://doi.org/10.1016/j.exphem.2006.04.016openalex-snapshot

Increased α2,6-sialylation of surface proteins on tolerogenic, immature dendritic cells and regulatory T cells

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Interleukin‐1β induces sialyl Lewis X on hepatocellular carcinoma HuH‐7 cells via enhanced expression of ST3Gal IV and FUT VI gene

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Specificity of DC‐SIGN for mannose‐ and fucose‐containing glycans

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The involvement of the monocytes/macrophages in chronic inflammation associated with atherosclerosis

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Identification of FcαRI as an Inhibitory Receptor that Controls Inflammation

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Interleukin-2 Signaling via STAT5 Constrains T Helper 17 Cell Generation

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Mammalian N-Glycan Branching Protects against Innate Immune Self-Recognition and Inflammation in Autoimmune Disease Pathogenesis

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inferredcites →https://doi.org/10.1016/j.immuni.2012.02.012openalex-snapshot

Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation

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Galectin-1 Deactivates Classically Activated Microglia and Protects from Inflammation-Induced Neurodegeneration

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Germinal Center B Cell Dynamics

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Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity

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N-Glycan Branching Decouples B Cell Innate and Adaptive Immunity to Control Inflammatory Demyelination

inferredcites →https://doi.org/10.1016/j.it.2009.07.006openalex-snapshot

Esterases and autoimmunity: the sialic acid acetylesterase pathway and the regulation of peripheral B cell tolerance

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The Glycoscience of Immunity

inferredcites →https://doi.org/10.1016/j.it.2018.11.007openalex-snapshot

The Mononuclear Phagocyte System: The Relationship between Monocytes and Macrophages

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Modulating leukocyte recruitment in inflammation

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Adaptive immunity

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Structure and function of immunoglobulins

inferredcites →https://doi.org/10.1016/j.jaci.2020.04.059openalex-snapshot

IgG Fc sialylation is regulated during the germinal center reaction following immunization with different adjuvants

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Rethinking mechanisms of autoimmune pathogenesis

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Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients

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Pathogenic effects of anti-citrullinated protein antibodies in rheumatoid arthritis – role for glycosylation

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Phosphoproteomic analyses reveal that galectin-1 augments the dynamics of B-cell receptor signaling

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Structural and functional diversity of neutrophil glycosylation in innate immunity and related disorders

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Liver Galβ1,4GlcNAc α2,6-sialyltransferase is down-regulated in human alcoholics: possible cause for the appearance of asialoconjugates

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Innate immunity: an overview

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Sialic acids as regulators of molecular and cellular interactions

inferredcites →https://doi.org/10.1016/j.tibs.2016.11.003openalex-snapshot

Translating the ‘Sugar Code’ into Immune and Vascular Signaling Programs

inferredcites →https://doi.org/10.1016/s0002-9440(10)64210-1openalex-snapshot

Glycosylation Might Provide Endothelial Zip Codes for Organ-Specific Leukocyte Traffic into Inflammatory Sites

inferredcites →https://doi.org/10.1016/s0009-8981(99)00248-xopenalex-snapshot

Alteration of sugar chains on α1-acid glycoprotein secreted following cytokine stimulation of HuH-7 cells in vitro

inferredcites →https://doi.org/10.1016/s0021-9258(17)44262-1openalex-snapshot

Structures of the oligosaccharides present at the three asparagine-linked glycosylation sites of human IgD.

inferredcites →https://doi.org/10.1016/s0021-9258(18)83148-9openalex-snapshot

Human hepatocyte-stimulating factor-III and interleukin-6 are structurally and immunologically distinct but regulate the production of the same acute phase plasma proteins

inferredcites →https://doi.org/10.1016/s0167-4838(00)00153-9openalex-snapshot

Alpha-1-acid glycoprotein

inferredcites →https://doi.org/10.1016/s0891-5849(00)00223-9openalex-snapshot

Intercellular adhesion molecule-1 (ICAM-1) expression and cell signaling cascades

inferredcites →https://doi.org/10.1016/s1074-7613(00)80149-1openalex-snapshot

Differentiation of Phagocytic Monocytes into Lymph Node Dendritic Cells In Vivo

inferredcites →https://doi.org/10.1017/s1462399408000719openalex-snapshot

Galectins: structure, function and therapeutic potential

inferredcites →https://doi.org/10.1021/bi00081a007openalex-snapshot

.epsilon.BP, a .beta.-galactoside-binding animal lectin, recognizes IgE receptor (Fc.epsilon.RI) and activates mast cells

inferredcites →https://doi.org/10.1021/bi981456kopenalex-snapshot

Amino Acid Residues That Influence FcεRI-Mediated Effector Functions of Human Immunoglobulin E

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B lymphocyte galactosyltransferase protein levels in normal individuals and in patients with rheumatoid arthritis

inferredcites →https://doi.org/10.1023/a:1006972307166openalex-snapshot

Inflammation-induced expression of sialyl Lewisx is not restricted to α1-acid glycoprotein but also occurs to a lesser extent on α1-antichymotrypsin and haptoglobin

inferredcites →https://doi.org/10.1038/373615a0openalex-snapshot

The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor

inferredcites →https://doi.org/10.1038/mi.2011.39openalex-snapshot

Structure and function relationships in IgA

inferredcites →https://doi.org/10.1038/nature04444openalex-snapshot

Restoring function in exhausted CD8 T cells during chronic viral infection

inferredcites →https://doi.org/10.1038/nature05115openalex-snapshot

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

inferredcites →https://doi.org/10.1038/nature06287openalex-snapshot

Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells

inferredcites →https://doi.org/10.1038/nature07201openalex-snapshot

Origin and physiological roles of inflammation

inferredcites →https://doi.org/10.1038/ncomms1333openalex-snapshot

Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis

inferredcites →https://doi.org/10.1038/ncomms6074openalex-snapshot

Fucose-based PAMPs prime dendritic cells for follicular T helper cell polarization via DC-SIGN-dependent IL-27 production

inferredcites →https://doi.org/10.1038/ni.1772openalex-snapshot

Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10

inferredcites →https://doi.org/10.1038/ni.3579openalex-snapshot

Regulation of autoantibody activity by the IL-23–TH17 axis determines the onset of autoimmune disease

inferredcites →https://doi.org/10.1038/ni0407-339openalex-snapshot

Rolling on N-linked glycans: a new way to present L-selectin binding sites

inferredcites →https://doi.org/10.1038/ni1283openalex-snapshot

Ablation of CD22 in ligand-deficient mice restores B cell receptor signaling

inferredcites →https://doi.org/10.1038/ni1442openalex-snapshot

Critical functions of N-glycans in L-selectin-mediated lymphocyte homing and recruitment

inferredcites →https://doi.org/10.1038/ni1482openalex-snapshot

Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death

inferredcites →https://doi.org/10.1038/ni1582openalex-snapshot

Functions of natural killer cells

inferredcites →https://doi.org/10.1038/nm.2862openalex-snapshot

Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1

inferredcites →https://doi.org/10.1038/nm.4148openalex-snapshot

Low-dose interleukin-2 treatment selectively modulates CD4+ T cell subsets in patients with systemic lupus erythematosus

inferredcites →https://doi.org/10.1038/nm0395-237openalex-snapshot

Glycosylation changes of IgG associated with rheumatooid arthritis can activate complement via the mannose-binding protein

inferredcites →https://doi.org/10.1038/nri1592openalex-snapshot

Dendritic cells as therapeutic vaccines against cancer

inferredcites →https://doi.org/10.1038/nri2056openalex-snapshot

Siglecs and their roles in the immune system

inferredcites →https://doi.org/10.1038/nri2156openalex-snapshot

Getting to the site of inflammation: the leukocyte adhesion cascade updated

inferredcites →https://doi.org/10.1038/nri2273openalex-snapshot

IgE in allergy and asthma today

inferredcites →https://doi.org/10.1038/nri2454openalex-snapshot

The who, how and where of antigen presentation to B cells

inferredcites →https://doi.org/10.1038/nri2536openalex-snapshot

Turning 'sweet' on immunity: galectin–glycan interactions in immune tolerance and inflammation

inferredcites →https://doi.org/10.1038/nri3401openalex-snapshot

Intravenous immunoglobulin therapy: how does IgG modulate the immune system?

inferredcites →https://doi.org/10.1038/nri3737openalex-snapshot

Siglec-mediated regulation of immune cell function in disease

inferredcites →https://doi.org/10.1038/nri3795openalex-snapshot

The generation of antibody-secreting plasma cells

inferredcites →https://doi.org/10.1038/nrrheum.2014.54openalex-snapshot

The role of CD22 and Siglec-G in B-cell tolerance and autoimmune disease

inferredcites →https://doi.org/10.1038/s41392-017-0002-5openalex-snapshot

Targeting IL-2: an unexpected effect in treating immunological diseases

inferredcites →https://doi.org/10.1038/s41467-018-05770-9openalex-snapshot

Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans

inferredcites →https://doi.org/10.1038/s41467-018-05771-8openalex-snapshot

Galectin-9 binds IgM-BCR to regulate B cell signaling

inferredcites →https://doi.org/10.1038/s41467-018-05795-0openalex-snapshot

Loss of GCNT2/I-branched glycans enhances melanoma growth and survival

inferredcites →https://doi.org/10.1038/s41467-019-13992-8openalex-snapshot

IgA subclasses have different effector functions associated with distinct glycosylation profiles

inferredcites →https://doi.org/10.1038/s41467-021-22365-zopenalex-snapshot

Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritis

inferredcites →https://doi.org/10.1038/s41580-020-00294-xopenalex-snapshot

Global view of human protein glycosylation pathways and functions

inferredcites →https://doi.org/10.1038/s41586-020-2311-zopenalex-snapshot

Sialylation of immunoglobulin E is a determinant of allergic pathogenicity

inferredcites →https://doi.org/10.1038/s41598-017-12495-0openalex-snapshot

Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health

inferredcites →https://doi.org/10.1038/s41598-018-31707-9openalex-snapshot

Pro inflammatory stimuli enhance the immunosuppressive functions of adipose mesenchymal stem cells-derived exosomes

inferredcites →https://doi.org/10.1038/srep23043openalex-snapshot

Metabolic Reprogramming by Hexosamine Biosynthetic and Golgi N-Glycan Branching Pathways

inferredcites →https://doi.org/10.1038/srep30392openalex-snapshot

Using CRISPR-Cas9 to quantify the contributions of O-glycans, N-glycans and Glycosphingolipids to human leukocyte-endothelium adhesion

inferredcites →https://doi.org/10.1038/srep42257openalex-snapshot

GlcNAc6ST-1 regulates sulfation of N-glycans and myelination in the peripheral nervous system

inferredcites →https://doi.org/10.1039/9781849732765-00094openalex-snapshot

Sialylation and dendritic cells: bridging innate and adaptive immune responses

inferredcites →https://doi.org/10.1042/bcj20190789openalex-snapshot

Loss of core fucosylation in both ST6GAL1 and its substrate enhances glycoprotein sialylation in mice

inferredcites →https://doi.org/10.1042/bj20070958openalex-snapshot

IL-6 and IL-8 increase the expression of glycosyltransferases and sulfotransferases involved in the biosynthesis of sialylated and/or sulfated Lewisx epitopes in the human bronchial mucosa

inferredcites →https://doi.org/10.1042/bj2710285openalex-snapshot

The structure and function of human IgA

inferredcites →https://doi.org/10.1046/j.1523-1755.2001.00489.xopenalex-snapshot

Charge-dependent binding of polymeric IgA1 to human mesangial cells in IgA nephropathy

inferredcites →https://doi.org/10.1053/j.gastro.2016.03.002openalex-snapshot

Core Fucosylation on T Cells, Required for Activation of T-Cell Receptor Signaling and Induction of Colitis in Mice, Is Increased in Patients With Inflammatory Bowel Disease

inferredcites →https://doi.org/10.1056/nejm199902113400607openalex-snapshot

Acute-Phase Proteins and Other Systemic Responses to Inflammation

inferredcites →https://doi.org/10.1073/pnas.0400851101openalex-snapshot

Masking of CD22 by cis ligands does not prevent redistribution of CD22 to sites of cell contact

inferredcites →https://doi.org/10.1073/pnas.1507706113openalex-snapshot

Sialic acid-modified antigens impose tolerance via inhibition of T-cell proliferation and de novo induction of regulatory T cells

inferredcites →https://doi.org/10.1073/pnas.1523968113openalex-snapshot

B-cell–independent sialylation of IgG

inferredcites →https://doi.org/10.1074/jbc.271.19.11090openalex-snapshot

Individually Distinct Ig Homology Domains in PECAM-1 Regulate Homophilic Binding and Modulate Receptor Affinity

inferredcites →https://doi.org/10.1074/jbc.c117.795138openalex-snapshot

Extrinsic sialylation is dynamically regulated by systemic triggers in vivo

inferredcites →https://doi.org/10.1074/jbc.m109.035196openalex-snapshot

Galectin-9 Is a High Affinity IgE-binding Lectin with Anti-allergic Effect by Blocking IgE-Antigen Complex Formation

inferredcites →https://doi.org/10.1074/jbc.m109.055475openalex-snapshot

Regulation of Phagocytosis in Macrophages by Neuraminidase 1

inferredcites →https://doi.org/10.1074/jbc.m110146200openalex-snapshot

A Small Region of the Natural Killer Cell Receptor, Siglec-7, Is Responsible for Its Preferred Binding to α2,8-Disialyl and Branched α2,6-Sialyl Residues

inferredcites →https://doi.org/10.1074/jbc.m111.225334openalex-snapshot

Glycosylation Affects Ligand Binding and Function of the Activating Natural Killer Cell Receptor 2B4 (CD244) Protein

inferredcites →https://doi.org/10.1074/jbc.m111.247981openalex-snapshot

Endothelial Surface N-Glycans Mediate Monocyte Adhesion and Are Targets for Anti-inflammatory Effects of Peroxisome Proliferator-activated Receptor γ Ligands

inferredcites →https://doi.org/10.1074/jbc.m111.276063openalex-snapshot

ST6Gal-I Regulates Macrophage Apoptosis via α2-6 Sialylation of the TNFR1 Death Receptor

inferredcites →https://doi.org/10.1074/jbc.m112.400929openalex-snapshot

Silencing α1,3-Fucosyltransferases in Human Leukocytes Reveals a Role for FUT9 Enzyme during E-selectin-mediated Cell Adhesion

inferredcites →https://doi.org/10.1074/jbc.m116.756502openalex-snapshot

The Role of Sialylated Glycans in Human Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1)-mediated Trans Homophilic Interactions and Endothelial Cell Barrier Function

inferredcites →https://doi.org/10.1074/jbc.m202069200openalex-snapshot

Lack of Fucose on Human IgG1 N-Linked Oligosaccharide Improves Binding to Human FcγRIII and Antibody-dependent Cellular Toxicity

inferredcites →https://doi.org/10.1074/jbc.m203258200openalex-snapshot

The Role of Constant Region Carbohydrate in the Assembly and Secretion of Human IgD and IgA1

inferredcites →https://doi.org/10.1074/jbc.m210665200openalex-snapshot

The Absence of Fucose but Not the Presence of Galactose or Bisecting N-Acetylglucosamine of Human IgG1 Complex-type Oligosaccharides Shows the Critical Role of Enhancing Antibody-dependent Cellular Cytotoxicity

inferredcites →https://doi.org/10.1074/jbc.m504528200openalex-snapshot

Human Serum IgM Glycosylation

inferredcites →https://doi.org/10.1074/jbc.m701890200openalex-snapshot

Control of T Cell-mediated Autoimmunity by Metabolite Flux to N-Glycan Biosynthesis

inferredcites →https://doi.org/10.1074/jbc.m800836200openalex-snapshot

Proteolytic Shedding of ST6Gal-I by BACE1 Regulates the Glycosylation and Function of α4β1 Integrins

inferredcites →https://doi.org/10.1074/jbc.r110.191429openalex-snapshot

Emerging Role of α2,6-Sialic Acid as a Negative Regulator of Galectin Binding and Function

inferredcites →https://doi.org/10.1074/jbc.r700016200openalex-snapshot

JAK-STAT Signaling: From Interferons to Cytokines

inferredcites →https://doi.org/10.1074/jbc.ra117.001207openalex-snapshot

Restricted processing of CD16a/Fc γ receptor IIIa N-glycans from primary human NK cells impacts structure and function

inferredcites →https://doi.org/10.1074/jbc.ra118.004998openalex-snapshot

CD16a with oligomannose-type N-glycans is the only “low-affinity” Fc γ receptor that binds the IgG crystallizable fragment with high affinity in vitro

inferredcites →https://doi.org/10.1074/jbc.ra120.015516openalex-snapshot

Fc γ receptor IIIa/CD16a processing correlates with the expression of glycan-related genes in human natural killer cells

inferredcites →https://doi.org/10.1074/mcp.m116.066746openalex-snapshot

Paucimannose-Rich N-glycosylation of Spatiotemporally Regulated Human Neutrophil Elastase Modulates Its Immune Functions*.

inferredcites →https://doi.org/10.1074/mcp.m117.066944openalex-snapshot

Identification of Fc Gamma Receptor Glycoforms That Produce Differential Binding Kinetics for Rituximab

inferredcites →https://doi.org/10.1074/mcp.ra119.001860openalex-snapshot

Decreased Immunoglobulin G Core Fucosylation, A Player in Antibody-dependent Cell-mediated Cytotoxicity, is Associated with Autoimmune Thyroid Diseases

inferredcites →https://doi.org/10.1080/00365540903036220openalex-snapshot

Activity of lysosomal exoglycosidases in serum and synovial fluid in patients with chronic Lyme and rheumatoid arthritis

inferredcites →https://doi.org/10.1080/19420862.2016.1218586openalex-snapshot

The immunoglobulin G1 N-glycan composition affects binding to each low affinity Fc γ receptor

inferredcites →https://doi.org/10.1080/19420862.2021.1893427openalex-snapshot

Fc galactosylation follows consecutive reaction kinetics and enhances immunoglobulin G hexamerization for complement activation

inferredcites →https://doi.org/10.1081/copd-120028701openalex-snapshot

Alveolar Macrophages as Orchestrators of COPD

inferredcites →https://doi.org/10.1083/jcb.153.6.1277openalex-snapshot

Cd44 Is a Major E-Selectin Ligand on Human Hematopoietic Progenitor Cells

inferredcites →https://doi.org/10.1084/jem.186.11.1853openalex-snapshot

A Role for Mac-1 (CDIIb/CD18) in Immune Complex–stimulated Neutrophil Function In Vivo: Mac-1 Deficiency Abrogates Sustained Fcγ Receptor–dependent Neutrophil Adhesion and Complement-dependent Proteinuria in Acute Glomerulonephritis

inferredcites →https://doi.org/10.1084/jem.186.8.1357openalex-snapshot

Neutrophil Emigration in the Skin, Lungs, and Peritoneum: Different Requirements for CD11/CD18 Revealed by CD18-deficient Mice

inferredcites →https://doi.org/10.1084/jem.189.8.1307openalex-snapshot

Deficiency in CD22, a B Cell–specific Inhibitory Receptor, Is Sufficient to Predispose to Development of High Affinity Autoantibodies

inferredcites →https://doi.org/10.1084/jem.20041276openalex-snapshot

Neutrophils mediate immune modulation of dendritic cells through glycosylation-dependent interactions between Mac-1 and DC-SIGN

inferredcites →https://doi.org/10.1084/jem.20142182openalex-snapshot

A single glycan on IgE is indispensable for initiation of anaphylaxis

inferredcites →https://doi.org/10.1084/jem.20151722openalex-snapshot

IFN-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity

inferredcites →https://doi.org/10.1093/eurjhf/hfp097openalex-snapshot

Galectin-3: A Novel Mediator of Heart Failure Development and Progression

inferredcites →https://doi.org/10.1093/glycob/9.10.1003openalex-snapshot

Hepatic acute phase induction of murine -galactoside 2,6 sialyltransferase (ST6Gal I) is IL-6 dependent and mediated by elevation of Exon H--containing class of transcripts

inferredcites →https://doi.org/10.1093/glycob/cwab108openalex-snapshot

N-acetyl-β-D-hexosaminidases mediate the generation of paucimannosidic proteins via a putative noncanonical truncation pathway in human neutrophils

inferredcites →https://doi.org/10.1093/glycob/cwg010openalex-snapshot

Opposite effects of galectin-1 on alternative metabolic pathways of L-arginine in resident, inflammatory, and activated macrophages

inferredcites →https://doi.org/10.1093/glycob/cwh131openalex-snapshot

Inflammation-induced transcriptional regulation of Golgi transporters required for the synthesis of sulfo sLex glycan epitopes

inferredcites →https://doi.org/10.1093/glycob/cwt014openalex-snapshot

Endothelial heterogeneity and adhesion molecules N-glycosylation: Implications in leukocyte trafficking in inflammation

inferredcites →https://doi.org/10.1093/glycob/cwu006openalex-snapshot

N-glycosylation deficiency reduces ICAM-1 induction and impairs inflammatory response

inferredcites →https://doi.org/10.1093/glycob/cwx026openalex-snapshot

Siglec-8 and Siglec-9 binding specificities and endogenous airway ligand distributions and properties

inferredcites →https://doi.org/10.1093/glycob/cwz096openalex-snapshot

Modulation of hepatocyte sialylation drives spontaneous fatty liver disease and inflammation

inferredcites →https://doi.org/10.1093/hmg/ddt632openalex-snapshot

Dysregulation of T cell receptor N-glycosylation: a molecular mechanism involved in ulcerative colitis

inferredcites →https://doi.org/10.1093/immadv/ltab012openalex-snapshot

α2-3 Sialic acid binding and uptake by human monocyte-derived dendritic cells alters metabolism and cytokine release and initiates tolerizing T cell programming

inferredcites →https://doi.org/10.1093/intimm/dxx025openalex-snapshot

Diversification of IgG effector functions

inferredcites →https://doi.org/10.1093/jn/131.9.2535sopenalex-snapshot

Glutamine Metabolism in Sepsis and Infection

inferredcites →https://doi.org/10.1093/rheumatology/ket342openalex-snapshot

Increased expression of Siglec-1 on peripheral blood monocytes and its role in mononuclear cell reactivity to autoantigen in rheumatoid arthritis

inferredcites →https://doi.org/10.1096/fasebj.9.10.7542213openalex-snapshot

The selecting: vascular adhesion molecules

inferredcites →https://doi.org/10.1096/fj.201902542ropenalex-snapshot

Regulation of neutrophil function by selective targeting of glycan epitopes expressed on the integrin CD11b/CD18

showing the first 200 of 315

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Galactia lindenii lectin type-II: Its potential use in thyroid cancer diagnosis

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Suppression of N-Glycosylation of Zinc Finger Protein 471 Affects Proliferation, Invasion, and Docetaxel Sensitivity of Tongue Squamous Cell Carcinoma via Regulation of c-Myc

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Low-scale production and purification of a biologically active optimized form of the antitumor protein growth arrest specific 1 (GAS1) in a mammalian system for post-translational analysis

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Reprogramming the glycocalyx: Advances in glycoengineering for immunomodulation and regenerative medicine

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A two-stage genome-wide association study to identify novel genetic loci associated with irAEs in lung cancer patients receiving PD-1/PD-L1 inhibitors

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Preparative separation of α2,3- and α2,6-sialylated N-glycans via linkage-specific charge modulation

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Activity values of the enzyme phosphomanomutase 2 for diagnosing the CDG Ia glycosylation defect

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Development of MAPT S305 mutation human iPSC lines exhibiting elevated 4R tau expression and functional alterations in neurons and astrocytes

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Multifaceted role of CD14 in innate immunity and tissue homeostasis

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Glycosylation of FGF/FGFR: An underrated sweet code regulating cellular signaling programs

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Low-dose fluoride exposure disrupts CD4+ T cell balance in humans and rats

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Advances in post-translational modifications and recurrent spontaneous abortion

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Polymorphisms of FUT9 and its relationship with susceptibility towards DHAV-3 in Pekin duck

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Fut8-Mediated Core Fucosylation of Toll-Like Receptor 4 Exacerbates Periodontitis Via Hyperactivation of NF-κB Signalling

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CD18 acts as an immune recognition molecule to induce the expressions of immune effectors through the Syk-ERK signaling pathway in oyster Crassostrea gigas

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N-glycosylation driven destabilization of BRASSINOSTEROID INSENSITIVE1 (BRI1) and BRI1-ASSOCIATED RECEPTOR KINASE1 (BAK1) in tomato during Ralstonia solanacearum infection

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Integrated multi-omics reveals that Notoginsenoside R1 mitigates inflammation mediated by NLRP3 and metabolic disruption in muscle contusion

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Total serum N-glycans mark visceral leishmaniasis in human infections with Leishmania infantum

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Further elucidation of GMPPB as a risk gene for depression through integrative multi-omics analyses

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Decoding serum N-Glycome signatures across COVID-19 symptomatic stages

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Post-translational modifications: Bridging viral infections and inflammatory bowel disease

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Advances in the interaction between gut microbiota and post-translational modifications of proteins

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Galectin-3 and its inhibitors: Overview and perspectives

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N-linked α2,6-sialylation of integrin β1 by the sialyltransferase ST6Gal1 promotes cell proliferation and stemness in gestational trophoblastic disease

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CRISPR activation screens map the genomic landscape of cancer glycome remodeling

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Galactose tolerance in adults with classical galactosaemia. Considering the gaps

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Development of an Antibody-Based Platform for the Analysis of Immune Cell-Specific N-linked Glycosylation

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Augmentation of Infrared Microscopy of White Blood Cells and Medical Measures for Rapid and Accurate Diagnosis of Bacterial or Viral Infections in Febrile Pediatric Oncology Patients: An Expert System-Based Study

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Site-Specific Glycosylation Analysis of Murine and Human Fcγ Receptors Reveals High Heterogeneity at Conserved N-Glycosylation Site

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Development and Validation of a Streamlined Workflow for Proteomic Analysis of Proteins and Post-translational Modifications from Dried Blood

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Carbon Dot-Infused Molecularly Imprinted Polymer for the Template-Specific Optical Sensing of Sialic Acid and Glucose and Its Integration with a Smartphone Device for On-Site Detection

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Serum N-Glycan Profiling of Patients with Narcolepsy Type 1 Using LC-MS/MS

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Measuring 15N and 13C Enrichment Levels in Sparsely Labeled Proteins Using High-Resolution and Tandem Mass Spectrometry

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Rapid Glass Wool Enrichment of Glycopeptides for MALDI-MS Analysis of Immunoglobulin G Glycosylation in COVID-19 Samples

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The role of N-glycosylation modification in the pathogenesis of liver cancer

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VCL/ICAM-1 pathway is associated with lung inflammatory damage in SARS-CoV-2 Omicron infection

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A genome-wide association study in 10,000 individuals links plasma N-glycome to liver disease and anti-inflammatory proteins

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Genetics of glycosylation in mammalian development and disease

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Advancing leprosy risk prediction through identification of a whole blood host transcriptomic biomarker signature including non-coding genes

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Epigenome-wide Mendelian randomization with multi-omics validation identifies epigenetic drivers of idiopathic pulmonary fibrosis

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Site-specific N -glycoproteomic analysis of four M2 macrophage subtypes derived from human THP-1 cells

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A machine learning-assisted analytical approach for the prediction of non-small cell lung cancer using UHPLC-HILIC-FLD serum N -glycan profiles

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ST6GAL1-mediated sialyl linkage switching drives cancer-promoting α2,6-sialo-protrusions radiating from anti-inflammatory TAMs

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The potential roles of IgG glycosylation in the development of non-communicable comorbidities in people with HIV

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Correlation of tongue coating thickness with microinflammatory state and oral microbiome in maintenance hemodialysis patients

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Applications of Mass Spectrometry Proteomic Methods to Immunoglobulins in the Clinical Laboratory

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A single-step, rapid, and versatile method for simultaneous detection of cell surface glycan profiles using fluorochrome-conjugated lectins

inferred← citeshttps://doi.org/10.1093/glycob/cwaf047openalex-snapshot

Serum N-glycosylation is altered in Nephropathic Cystinosis

inferred← citeshttps://doi.org/10.1093/glycob/cwag018openalex-snapshot

N-glycan branching on plasma proteins: a sweet fingerprint of coronary artery disease

inferred← citeshttps://doi.org/10.1093/jalm/jfaf147openalex-snapshot

Influence of Protein Glycosylation on the Measurement of Soluble Urokinase Plasminogen Activator Receptor

inferred← citeshttps://doi.org/10.1093/jleuko/qiaf113openalex-snapshot

Posttranslational sialylation and its impact on neutrophil recruitment

inferred← citeshttps://doi.org/10.1096/fj.202501962ropenalex-snapshot

Bovine Endometrium Drives and Responds to Divergence of In Vitro Produced Conceptus Biochemistry

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Development of MAPT S305 mutation models exhibiting elevated 4R tau expression, resulting in altered neuronal and astrocytic function

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Metabolomics unveiled the impact of alterations in nucleotide glucose metabolism on palmitic acid-induced TLR4 activation in THP-1 macrophages

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Down regulation of Engase in Caenorhabditis elegans may improve its stresses adaptivity

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ST6GAL1-mediated sialyl linkage switching in tumor-associated macrophages drives cancer-promoting nanotubes carrying α2,6-sialylation in anti-inflammatory cells

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Decoding the Glycan Signature: Unraveling N -Glycosylation Alterations in Glycogen Storage Disease Ia and Ib

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A Serum N‐Glycan Ratio Associated With Disease Severity and Treatment Response in Psoriasis

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Development of a novel test of splenic function for use in a clinical diagnostic laboratory

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Human γδ T Cell Function Is Impaired Upon Mevalonate Pathway Inhibition

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Understanding inhibitory receptor function in neutrophils through the lens of CLEC12A

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Neisserial adhesin A (NadA) binds human Siglec-5 and Siglec-14 with high affinity and promotes bacterial adhesion/invasion

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Transcriptomic investigation of agonistic behaviors of boxer shrimps (Stenopus species): insights into the potential neural signaling roles of dopamine and acetylcholine

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Serum N-glycan NA3Fb identified as a prognostic biomarker of poor outcome in HBV-related hepatocellular carcinoma

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Integrating transcriptomics, glycomics and glycoproteomics to characterize hepatitis B virus-associated hepatocellular carcinoma

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FUT11-Driven fucosylation coordinates K63 ubiquitination of keratin 17 to sustain psoriatic keratinocytes hyperproliferation

inferred← citeshttps://doi.org/10.1186/s12967-025-07455-6openalex-snapshot

Serum N-glycomics for non-invasive detection of significant liver pathology across clinical phases of treatment-naïve chronic hepatitis B

inferred← citeshttps://doi.org/10.1186/s13052-026-02273-yopenalex-snapshot

The association between plasma IgG N-glycosylation and viral encephalitis in children: a hospital-based case-control study

inferred← citeshttps://doi.org/10.1186/s13075-025-03505-yopenalex-snapshot

Profiling of IgG N-glycosylation for axial spondyloarthritis and other rheumatic diseases

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Immunoglobulin G and plasma glycome in early rheumatoid arthritis differ from matched controls and link less fat-free mass to an accelerated aging phenotype: an exploratory study

inferred← citeshttps://doi.org/10.1212/nxi.0000000000200502openalex-snapshot

Plasma N -Glycan Profiling Enhances Diagnostic Precision in Multiple Sclerosis, AQP4-Ab NMOSD, and MOGAD

inferred← citeshttps://doi.org/10.1371/journal.pone.0329640openalex-snapshot

Integrating bioinformatics and machine learning to elucidate the role of protein glycosylation-related genes in the pathogenesis of diabetic kidney disease

inferred← citeshttps://doi.org/10.1371/journal.pone.0357709openalex-snapshot

Dysregulation of the serum and IgG N-glycome in decompensated cirrhosis and its association with Model for End-Stage Liver Disease-Sodium (MELD-Na)

inferred← citeshttps://doi.org/10.17513/spno.32011openalex-snapshot

SELECTINS OF TUMOR CELLS AND VASCULAR MICROENVIROMENT AS TARGETS FOR ANTI-CANCER DRUG DELIVERY

inferred← citeshttps://doi.org/10.18786/2072-0505-2024-52-005openalex-snapshot

The content of soluble forms of galectins -1, -3, -4, -7, -9 in patients with renal cell cancer of various morphological types

inferred← citeshttps://doi.org/10.21037/tcr-2024-2436openalex-snapshot

Insight into dipeptidase 1: structure, function, and mechanism in gastrointestinal cancer diseases

inferred← citeshttps://doi.org/10.21203/rs.3.rs-10767266/v1openalex-snapshot

Characterization of N-Glycosylation Remodeling in Cerebrospinal Fluid Extracellular Vesicles in Children with Purulent Meningitis and Viral Meningitis: An Exploratory Glycomics Study Based on MALDI-TOF/TOF-MS

inferred← citeshttps://doi.org/10.21203/rs.3.rs-3341499/v1openalex-snapshot

Integrating transcriptomics, glycomics and glycoproteomics to characterize hepatitis B virus-associated hepatocellular carcinoma

inferred← citeshttps://doi.org/10.21203/rs.3.rs-3341499/v2openalex-snapshot

Integrating Transcriptomics, Glycomics And Glycoproteomics To Characterize Hepatitis B Virus-associated Hepatocellular Carcinoma

inferred← citeshttps://doi.org/10.21203/rs.3.rs-4406005/v1openalex-snapshot

Galactia lindenii lectin type-II. Proposal of its potential use in diagnostic tools

inferred← citeshttps://doi.org/10.2147/jir.s437266openalex-snapshot

Analysis and Verification of Glycosylation Characteristics of Septic Acute Kidney Injury

inferred← citeshttps://doi.org/10.2147/jir.s496099openalex-snapshot

IL-8 Downregulation Mediates the Beneficial Effects of Infection-Induced Fever on Breast Cancer Prognosis

inferred← citeshttps://doi.org/10.2147/jir.s529858openalex-snapshot

Swainsonine Protects Human Thyrocytes from Fas-Induced Apoptosis: In vitro Study on Nthy-Ori 3-1 Cell Line

inferred← citeshttps://doi.org/10.2147/pgpm.s463608openalex-snapshot

Identification and Validation of Glycosylation-Related Genes in Obesity and MASH: Insights from Human Liver Samples and a High-Fat Diet Mouse Model

inferred← citeshttps://doi.org/10.33393/jcb.2026.3772openalex-snapshot

From glycosylation to inflammation: insights from NMR-Derived GlycA and GlycB

inferred← citeshttps://doi.org/10.3389/fcvm.2023.1052959openalex-snapshot

Galectin functions in cancer-associated inflammation and thrombosis

inferred← citeshttps://doi.org/10.3389/fimmu.2023.1168023openalex-snapshot

Targeting protein glycosylation to regulate inflammation in the respiratory tract: novel diagnostic and therapeutic candidates for chronic respiratory diseases

inferred← citeshttps://doi.org/10.3389/fimmu.2024.1429302openalex-snapshot

α2,6 sialylation distinguishes a novel active state in CD4+ and CD8+ cells during acute Toxoplasma gondii infection

inferred← citeshttps://doi.org/10.3389/fimmu.2025.1655354openalex-snapshot

Immunopathology in PMM2-CDG: Defective glycosylation impact in the TNFα -TNFR1 signalling pathway

inferred← citeshttps://doi.org/10.3389/fimmu.2026.1789537openalex-snapshot

MesenSistem-EB: systemic haploidentical mesenchymal stem cell therapy in recessive dystrophic epidermolysis bullosa associated with clinical benefits and correlated with MCP1 and sCD40L dynamics

inferred← citeshttps://doi.org/10.3389/fimmu.2026.1875823openalex-snapshot

Altered duodenal N6-methyladenosine levels in common variable immunodeficiency associate with duodenal microbiota

inferred← citeshttps://doi.org/10.3389/fncel.2024.1335688openalex-snapshot

The association between plasma IgG N-glycosylation and neonatal hypoxic–ischemic encephalopathy: a case-control study

inferred← citeshttps://doi.org/10.3389/fonc.2023.1200646openalex-snapshot

Mechanisms of immune modulation in the tumor microenvironment and implications for targeted therapy

inferred← citeshttps://doi.org/10.3389/fonc.2026.1935795openalex-snapshot

Multi-modal spatial glycomic analysis of lymphoid aggregates in prostate and pancreatic cancer tissues

inferred← citeshttps://doi.org/10.3389/frans.2022.1021008openalex-snapshot

Applying imaging mass spectrometry to define the N-glycan profiles of co-localized virus and immune cell infiltrates in post-COVID-19 infected lung autopsy tissues

inferred← citeshttps://doi.org/10.3390/antib13010009openalex-snapshot

Anastrozole and Tamoxifen Impact on IgG Glycome Composition Dynamics in Luminal A and Luminal B Breast Cancers

inferred← citeshttps://doi.org/10.3390/biology14060611openalex-snapshot

Glycosylation and Acylation: Important Regulators of Immune Cell Fate Decisions

inferred← citeshttps://doi.org/10.3390/biom13020375openalex-snapshot

IgG N-Glycosylation Is Altered in Coronary Artery Disease

inferred← citeshttps://doi.org/10.3390/biom13040605openalex-snapshot

The N-Glycosylation of Total Plasma Proteins and IgG in Atrial Fibrillation

inferred← citeshttps://doi.org/10.3390/biom13060954openalex-snapshot

Anti-TNF Biologicals Enhance the Anti-Inflammatory Properties of IgG N-Glycome in Crohn’s Disease

inferred← citeshttps://doi.org/10.3390/biom14050513openalex-snapshot

The Exploitation of the Glycosylation Pattern in Asthma: How We Alter Ancestral Pathways to Develop New Treatments

inferred← citeshttps://doi.org/10.3390/biom15040476openalex-snapshot

Ameliorative Effect of Banana Lectin in TNBS-Induced Colitis in C57BL/6 Mice Relies on the Promotion of Antioxidative Mechanisms in the Colon

inferred← citeshttps://doi.org/10.3390/biom16101419openalex-snapshot

Glycosylation Heterogeneity of α1-Acid Glycoprotein: Disease-Associated Glycoform Remodeling, Regulatory Mechanisms, and Clinical Translation

inferred← citeshttps://doi.org/10.3390/biomedicines13082034openalex-snapshot

Glycomics in Human Diseases and Its Emerging Role in Biomarker Discovery

inferred← citeshttps://doi.org/10.3390/cells15161497openalex-snapshot

ST6GAL1 Is a Functional Regulator of UVA-Induced Photoaging in Human Dermal Fibroblasts

inferred← citeshttps://doi.org/10.3390/cells15171525openalex-snapshot

Cell Membrane Biophysics as a Therapeutic Interface for Nanomedicine: From Disease-Associated Remodeling to Translational Qualification

inferred← citeshttps://doi.org/10.3390/ijms242015139openalex-snapshot

Molecular and Cellular Insights: A Focus on Glycans and the HNK1 Epitope in Autism Spectrum Disorder

inferred← citeshttps://doi.org/10.3390/ijms242216490openalex-snapshot

Metabolic Markers and Association of Biological Sex in Lupus Nephritis

inferred← citeshttps://doi.org/10.3390/ijms25094905openalex-snapshot

Glucosamine and Silibinin Alter Cartilage Homeostasis through Glycosylation and Cellular Stresses in Human Chondrocyte Cells

inferred← citeshttps://doi.org/10.3390/ijms25126432openalex-snapshot

The Impact of Protein Glycosylation on the Identification of Patients with Pediatric Appendicitis

inferred← citeshttps://doi.org/10.3390/ijms26052206openalex-snapshot

Hypothetical Pathogenetic Model of Membranous Nephropathy

inferred← citeshttps://doi.org/10.3390/ijms26115196openalex-snapshot

Effect of a Laparoscopic Donor Nephrectomy in Healthy Living Kidney Donors on the Acute Phase Response Using Either Propofol or Sevoflurane Anesthesia

inferred← citeshttps://doi.org/10.3390/ijms26167727openalex-snapshot

Transparent Machine Learning Reveals Diagnostic Glycan Biomarkers in Subarachnoid Hemorrhage and Vasospasm

inferred← citeshttps://doi.org/10.3390/ijms27093907openalex-snapshot

SAA4: An Underdog Within the Serum Amyloid a Superfamily?

inferred← citeshttps://doi.org/10.3390/metabo14100525openalex-snapshot

Hyperglycosylation as an Indicator of Aging in the Bone Metabolome of Oryzias latipes

inferred← citeshttps://doi.org/10.3390/molecules29061298openalex-snapshot

The Impact of Glycolysis and Its Inhibitors on the Immune Response to Inflammation and Autoimmunity

inferred← citeshttps://doi.org/10.3390/molecules29225222openalex-snapshot

N-glycosylation Modification Reveals Insights into the Oxidative Reactions of Liver in Wuzhishan Pigs

inferred← citeshttps://doi.org/10.4049/jimmunol.2400447openalex-snapshot

IgG Glycosylation: Biomarker, Functional Modulator, and Structural Component

inferred← citeshttps://doi.org/10.4081/btvb.2026.444openalex-snapshot

Platelet-driven remodeling of cancer cell glycoproteins fuels inflammation and metastasis

inferred← citeshttps://doi.org/10.6084/m9.figshare.25522610openalex-snapshot

Additional file 1 of Integrating transcriptomics, glycomics and glycoproteomics to characterize hepatitis B virus-associated hepatocellular carcinoma

inferred← citeshttps://doi.org/10.6084/m9.figshare.25522751openalex-snapshot

Additional file 2 of Integrating transcriptomics, glycomics and glycoproteomics to characterize hepatitis B virus-associated hepatocellular carcinoma

inferred← citeshttps://doi.org/10.64898/2026.01.29.26345171openalex-snapshot

Integrated Cardiac and Circulating N-glycan Signatures Reflect Atrial Remodeling in Patients with Atrial Fibrillation

inferred← citeshttps://doi.org/10.64898/2026.04.25.720834openalex-snapshot

Systems serology of responses against tumor antigens in ovarian cancer reveal disrupted Fc-mediated immunity

inferred← citeshttps://doi.org/10.7150/ijbs.93806openalex-snapshot

Glycosylation Targeting: A Paradigm Shift in Cancer Immunotherapy

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