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MicroRNA-451a and Th1/Th2 ratio inform inflammation, septic organ injury, and mortality risk in sepsis patients

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/jama.2016.0287openalex-snapshot
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
inferredcites →https://doi.org/10.1002/art.38269openalex-snapshot
MicroRNA‐451 Down‐Regulates Neutrophil Chemotaxis via p38 MAPK
inferredcites →https://doi.org/10.1007/s00408-020-00362-1openalex-snapshot
Increased Th17 and Th22 Cell Percentages Predict Acute Lung Injury in Patients with Sepsis
inferredcites →https://doi.org/10.1007/s10753-017-0514-8openalex-snapshot
miRNA-451a Targets IFN Regulatory Factor 8 for the Progression of Systemic Lupus Erythematosus
inferredcites →https://doi.org/10.1007/s10753-018-0890-8openalex-snapshot
Review: the Role and Mechanisms of Macrophage Autophagy in Sepsis
inferredcites →https://doi.org/10.1007/s11845-020-02382-5openalex-snapshot
The correlation between Jun N-terminal kinase pathway-associated phosphatase and Th1 cell or Th17 cell in sepsis and their potential roles in clinical sepsis management
inferredcites →https://doi.org/10.1007/s11886-020-01277-2openalex-snapshot
Sepsis-Induced Cardiomyopathy: a Comprehensive Review
inferredcites →https://doi.org/10.1007/s12013-020-00900-xopenalex-snapshot
Identification of Differentially Expressed miRNAs in the Response of Spleen CD4+ T Cells to Electroacupuncture in Senescence-Accelerated Mice
inferredcites →https://doi.org/10.1038/ni.3398openalex-snapshot
Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis
inferredcites →https://doi.org/10.1055/s-0039-1694995openalex-snapshot
Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation
inferredcites →https://doi.org/10.1080/00365513.2021.1952483openalex-snapshot
Blood suPAR, Th1 and Th17 cell may serve as potential biomarkers for elderly sepsis management
inferredcites →https://doi.org/10.1089/ten.teb.2018.0157openalex-snapshot
The Bidirectional Interactions Between Inflammation and Coagulation in Fracture Hematoma
inferredcites →https://doi.org/10.1097/ccm.0000000000004155openalex-snapshot
The Epidemiology of Sepsis in Chinese ICUs: A National Cross-Sectional Survey
inferredcites →https://doi.org/10.1111/imj.14199openalex-snapshot
Sepsis and septic shock: current approaches to management
inferredcites →https://doi.org/10.1146/annurev-immunol-061020-053702openalex-snapshot
Cytokine Regulation and Function in T Cells
inferredcites →https://doi.org/10.1155/2020/8032806openalex-snapshot
Circulating Th1 and Th2 Subset Accumulation Kinetics in Septic Patients with Distinct Infection Sites: Pulmonary versus Nonpulmonary
inferredcites →https://doi.org/10.1164/rccm.201504-0781ocopenalex-snapshot
Assessment of Global Incidence and Mortality of Hospital-treated Sepsis: Current Estimates and Limitations
inferredcites →https://doi.org/10.1172/jci128075openalex-snapshot
Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFN-γ in NK cells
inferredcites →https://doi.org/10.1186/s12967-019-1811-9openalex-snapshot
Early and dynamic alterations of Th2/Th1 in previously immunocompetent patients with community-acquired severe sepsis: a prospective observational study
inferredcites →https://doi.org/10.1186/s13054-020-03327-1openalex-snapshot
Gut-liver crosstalk in sepsis-induced liver injury
inferredcites →https://doi.org/10.1590/1678-4685-gmb-2020-0009openalex-snapshot
Overexpression of miR-451a in sepsis and septic shock patients is involved in the regulation of sepsis-associated cardiac dysfunction and inflammation
inferredcites →https://doi.org/10.22034/iji.2020.87266.1793openalex-snapshot
IL-6 and IL-10 Closely Correlate with Bacterial Bloodstream Infection.
inferredcites →https://doi.org/10.3389/fimmu.2020.01722openalex-snapshot
Pulmonary Innate Immune Response Determines the Outcome of Inflammation During Pneumonia and Sepsis-Associated Acute Lung Injury
inferredcites →https://doi.org/10.3389/fimmu.2021.703972openalex-snapshot
Targeting Mitochondrial-Derived Reactive Oxygen Species in T Cell-Mediated Autoimmune Diseases
inferredcites →https://doi.org/10.3390/genes11111327openalex-snapshot
Identification and Validation of Potential miRNAs, as Biomarkers for Sepsis and Associated Lung Injury: A Network-Based Approach
inferredcites →https://doi.org/10.3390/ijms20215376openalex-snapshot
The Pathogenesis of Sepsis and Potential Therapeutic Targets
inferredcites →https://doi.org/10.3892/mmr.2019.10587openalex-snapshot
MicroRNA‑451 relieves inflammation in cerebral ischemia‑reperfusion via the Toll‑like receptor 4/MyD88/NF‑κB signaling pathway

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4660743openalex-extracted
inferred← citeshttps://doi.org/10.1002/cre2.70099openalex-snapshot
Extracellular Vesicles Derived From Lipopolysaccharide‐Challenged Gingival Fibroblast Reveal Distinct miRNA Expression Patterns Associated With Reduced Cancer Survival
inferred← citeshttps://doi.org/10.1007/s11596-024-2957-0openalex-snapshot
Acupuncture Treats Sepsis through Immune Modulation and Organ Protection
inferred← citeshttps://doi.org/10.1016/j.cyto.2026.157157openalex-snapshot
LUCAT1/PTBP1/HIF-1α feedback loop promotes T cell over-differentiation and Th1/Th2-skewed immune imbalance in sepsis via glucose metabolism
inferred← citeshttps://doi.org/10.1016/j.gene.2024.149137openalex-snapshot
Transcriptomic analysis of key genes and signaling pathways in sepsis-associated intestinal mucosal barrier damage
inferred← citeshttps://doi.org/10.1093/jimmun/vkae049openalex-snapshot
Regulation of IL-17A–mediated hypersensitivity by extracellular vesicles and lipid nanoparticles carrying miR-451a
inferred← citeshttps://doi.org/10.12677/acm.2024.1451707openalex-snapshot
Transcriptomic Analysis of Key Genes and Signaling Pathways in Sepsis-Associated Intestinal Mucosal Barrier Damage
inferred← citeshttps://doi.org/10.12677/pi.2024.131005openalex-snapshot
Research Progress on the Prevention and Treatment of Sepsis in Traditional Chinese Medicine
inferred← citeshttps://doi.org/10.1615/critrevimmunol.2024051413openalex-snapshot
The Value of Systemic Immune-Inflammation Index and T Cell Subsets in the Severity and Prognosis of Sepsis
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3511331/v1openalex-snapshot
Circulating miR-451a, miR-5571-3p, CLN6, HSD11B1 and PDE4 levels in differential diagnosis of Granulomatous lobular mastitis, breast cancer and breast fibroadenoma
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1298041openalex-snapshot
Elucidating common pathogenic transcriptional networks in infective endocarditis and sepsis: integrated insights from biomarker discovery and single-cell RNA sequencing
inferred← citeshttps://doi.org/10.3389/fimmu.2026.1816500openalex-snapshot
Interferon-gamma to interleukin-10 ratio is negatively associated with short-term mortality risk in sepsis patients: a retrospective study based on immune balance index
inferred← citeshttps://doi.org/10.5498/wjp.v15.i7.104812openalex-snapshot
Meta-analysis of the incidence and risk factors of postoperative delirium in organ transplant patients
inferred← citeshttps://doi.org/10.7150/thno.86792openalex-snapshot
Blocking Tim-3 enhances the anti-tumor immunity of STING agonist ADU-S100 by unleashing CD4+ T cells through regulating type 2 conventional dendritic cells
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