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Aquaporins in Cancer Biology

https://doi.org/10.3389/fonc.2022.782829

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/(sici)1096-9896(199806)185:2<191::aid-path81>3.0.co;2-popenalex-snapshot

Increased MUC6 apomucin expression is a characteristic of reactive biliary epithelium in chronic viral hepatitis

inferredcites →https://doi.org/10.1002/9781119000822.hfcm002openalex-snapshot

Biological Hallmarks of Cancer

inferredcites →https://doi.org/10.1002/ajh.10476openalex-snapshot

Aquaporin expression in human lymphocytes and dendritic cells

inferredcites →https://doi.org/10.1002/ana.22657openalex-snapshot

Anti–Aquaporin‐4 monoclonal antibody blocker therapy for neuromyelitis optica

inferredcites →https://doi.org/10.1002/ar.10123openalex-snapshot

Aquaporin‐1 expression in the chick embryo chorioallantoic membrane

inferredcites →https://doi.org/10.1002/biof.1340openalex-snapshot

Intracellular cysteine oxidation is modulated by aquaporin‐8‐mediated hydrogen peroxide channeling in leukaemia cells

inferredcites →https://doi.org/10.1002/glia.20318openalex-snapshot

Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin‐4 water channels

inferredcites →https://doi.org/10.1002/glia.20524openalex-snapshot

Expression and function of water channels (aquaporins) in migrating malignant astrocytes

inferredcites →https://doi.org/10.1002/hep.1840380421openalex-snapshot

Ontogeny, Distribution, and Possible Functional Implications of An Unusual Aquaporin, Aqp8, in Mouse Liver

inferredcites →https://doi.org/10.1002/iub.243openalex-snapshot

Aquaporin‐1 activity of plasma membrane affects HT20 colon cancer cell migration

inferredcites →https://doi.org/10.1002/jnr.21224openalex-snapshot

Expression pattern of the water channel aquaporin‐4 in human gliomas is associated with blood–brain barrier disturbance but not with patient survival

inferredcites →https://doi.org/10.1002/jso.24605openalex-snapshot

Differential expression of aquaporin‐3 and aquaporin‐5 in pancreatic ductal adenocarcinoma

inferredcites →https://doi.org/10.1002/mc.22712openalex-snapshot

Down‐regulation of aquaporin 5‐mediated epithelial‐mesenchymal transition and anti‐metastatic effect by natural product Cairicoside E in colorectal cancer

inferredcites →https://doi.org/10.1002/oby.20792openalex-snapshot

Human aquaporin‐11 is a water and glycerol channel and localizes in the vicinity of lipid droplets in human adipocytes

inferredcites →https://doi.org/10.1002/path.2702openalex-snapshot

Expression of aquaporin 5 increases proliferation and metastasis potential of lung cancer

inferredcites →https://doi.org/10.1002/stem.101openalex-snapshot

miR-200 Regulates PDGF-D-Mediated Epithelial–Mesenchymal Transition, Adhesion, and Invasion of Prostate Cancer Cells

inferredcites →https://doi.org/10.1006/geno.1995.0029openalex-snapshot

The MouseAquaporin-1Gene

inferredcites →https://doi.org/10.1006/mvre.1999.2158openalex-snapshot

Water Channel (Aquaporin 1) Expression and Distribution in Mammary Carcinomas and Glioblastomas

inferredcites →https://doi.org/10.1007/s00018-006-6028-4openalex-snapshot

Physiological roles of glycerol-transporting aquaporins: the aquaglyceroporins

inferredcites →https://doi.org/10.1007/s00018-007-7163-2openalex-snapshot

Aquaporins with selectivity for unconventional permeants

inferredcites →https://doi.org/10.1007/s00018-016-2142-0openalex-snapshot

Aquaporin-5: from structure to function and dysfunction in cancer

inferredcites →https://doi.org/10.1007/s00292-008-1039-6openalex-snapshot

Aquaporin-1-Expression bei invasiven Mammakarzinomen

inferredcites →https://doi.org/10.1007/s00401-005-0984-xopenalex-snapshot

Redistribution of the water channel protein aquaporin-4 and the K+ channel protein Kir4.1 differs in low- and high-grade human brain tumors

inferredcites →https://doi.org/10.1007/s00404-011-1908-8openalex-snapshot

Proliferation inhibition of cisplatin and aquaporin 5 expression in human ovarian cancer cell CAOV3

inferredcites →https://doi.org/10.1007/s00424-006-0138-6openalex-snapshot

Cells move when ions and water flow

inferredcites →https://doi.org/10.1007/s00424-007-0357-5openalex-snapshot

Aquaporins and cell migration

inferredcites →https://doi.org/10.1007/s00467-006-0411-0openalex-snapshot

Aquaporin-4 and brain edema

inferredcites →https://doi.org/10.1007/s00535-013-0827-9openalex-snapshot

The expression and role of Aquaporin 5 in esophageal squamous cell carcinoma

inferredcites →https://doi.org/10.1007/s10495-014-0966-3openalex-snapshot

Evidence for necrosis, but not apoptosis, in human hepatoma cells with knockdown of mitochondrial aquaporin-8

inferredcites →https://doi.org/10.1007/s10585-006-9014-1openalex-snapshot

Invadopodia: Specialized Cell Structures for Cancer Invasion

inferredcites →https://doi.org/10.1007/s10735-016-9657-4openalex-snapshot

Expression of AQP6 and AQP8 in epithelial ovarian tumor

inferredcites →https://doi.org/10.1007/s11060-005-9057-1openalex-snapshot

Increased expression of aquaporin 1 in human hemangioblastomas and its correlation with cyst formation

inferredcites →https://doi.org/10.1007/s11596-008-0327-yopenalex-snapshot

Correlation between the expression of aquaporin 1 and hypoxia-inducible factor 1 in breast cancer tissues

inferredcites →https://doi.org/10.1007/s13277-013-0712-4openalex-snapshot

Aquaporin 5 promotes the proliferation and migration of human gastric carcinoma cells

inferredcites →https://doi.org/10.1016/j.addr.2010.11.001openalex-snapshot

Focal adhesion kinase and its signaling pathways in cell migration and angiogenesis

inferredcites →https://doi.org/10.1016/j.bbagen.2013.09.017openalex-snapshot

Aquaporin-facilitated transmembrane diffusion of hydrogen peroxide

inferredcites →https://doi.org/10.1016/j.bbagen.2013.10.032openalex-snapshot

Aquaporin and brain diseases

inferredcites →https://doi.org/10.1016/j.bbagen.2015.08.023openalex-snapshot

Beyond water homeostasis: Diverse functional roles of mammalian aquaporins

inferredcites →https://doi.org/10.1016/j.bbamcr.2014.01.011openalex-snapshot

Specific aquaporins facilitate Nox-produced hydrogen peroxide transport through plasma membrane in leukaemia cells

inferredcites →https://doi.org/10.1016/j.bbamem.2014.09.001openalex-snapshot

Key roles of aquaporins in tumor biology

inferredcites →https://doi.org/10.1016/j.bbamem.2021.183573openalex-snapshot

The effects of trifluoperazine on brain edema, aquaporin-4 expression and metabolic markers during the acute phase of stroke using photothrombotic mouse model

inferredcites →https://doi.org/10.1016/j.bbrc.2005.03.046openalex-snapshot

Identification of a novel aquaporin, AQP12, expressed in pancreatic acinar cells

inferredcites →https://doi.org/10.1016/j.bbrc.2007.12.073openalex-snapshot

The effect of aquaporin 5 overexpression on the Ras signaling pathway

inferredcites →https://doi.org/10.1016/j.bbrc.2014.09.032openalex-snapshot

Aquaporin 0 plays a pivotal role in refractive index gradient development in mammalian eye lens to prevent spherical aberration

inferredcites →https://doi.org/10.1016/j.bbrc.2016.01.153openalex-snapshot

Aquaporin-9 facilitates membrane transport of hydrogen peroxide in mammalian cells

inferredcites →https://doi.org/10.1016/j.bbrc.2016.02.010openalex-snapshot

Involvement of aquaporin-3 in epidermal growth factor receptor signaling via hydrogen peroxide transport in cancer cells

inferredcites →https://doi.org/10.1016/j.bbrc.2017.02.013openalex-snapshot

RNA interference influenced the proliferation and invasion of XWLC-05 lung cancer cells through inhibiting aquaporin 3

inferredcites →https://doi.org/10.1016/j.biopha.2009.12.003openalex-snapshot

Expression profile of multiple aquaporins in human gastric carcinoma and its clinical significance

inferredcites →https://doi.org/10.1016/j.canlet.2008.01.029openalex-snapshot

Overexpression of AQP5, a putative oncogene, promotes cell growth and transformation

inferredcites →https://doi.org/10.1016/j.ccr.2007.12.003openalex-snapshot

Systemic Spread Is an Early Step in Breast Cancer

inferredcites →https://doi.org/10.1016/j.ceb.2003.10.006openalex-snapshot

Epithelial–mesenchymal transitions in development and pathologies

inferredcites →https://doi.org/10.1016/j.ceb.2004.07.010openalex-snapshot

Regulation of matrix biology by matrix metalloproteinases

inferredcites →https://doi.org/10.1016/j.cell.2010.01.009openalex-snapshot

Inactivation of Peroxiredoxin I by Phosphorylation Allows Localized H2O2 Accumulation for Cell Signaling

inferredcites →https://doi.org/10.1016/j.cell.2014.02.052openalex-snapshot

Water Permeation Drives Tumor Cell Migration in Confined Microenvironments

inferredcites →https://doi.org/10.1016/j.cell.2020.03.037openalex-snapshot

Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema

inferredcites →https://doi.org/10.1016/j.celrep.2019.05.097openalex-snapshot

Aquaporin-4 Surface Trafficking Regulates Astrocytic Process Motility and Synaptic Activity in Health and Autoimmune Disease

inferredcites →https://doi.org/10.1016/j.devcel.2007.10.007openalex-snapshot

The PAR Proteins: Fundamental Players in Animal Cell Polarization

inferredcites →https://doi.org/10.1016/j.ejca.2009.09.023openalex-snapshot

Aquaporin-4 contributes to the resolution of peritumoural brain oedema in human glioblastoma multiforme after combined chemotherapy and radiotherapy

inferredcites →https://doi.org/10.1016/j.humpath.2006.07.015openalex-snapshot

Expression of aquaporin 3 (AQP3) in normal and neoplastic lung tissues

inferredcites →https://doi.org/10.1016/j.humpath.2010.07.022openalex-snapshot

Relationship of aquaporin 1, 3, and 5 expression in lung cancer cells to cellular differentiation, invasive growth, and metastasis potential

inferredcites →https://doi.org/10.1016/j.ijgo.2007.12.006openalex-snapshot

Expression of aquaporin‐1 in normal, hyperplasic, and carcinomatous endometria

inferredcites →https://doi.org/10.1016/j.jmb.2008.07.089openalex-snapshot

Evidence against Involvement of Aquaporin-4 in Cell–Cell Adhesion

inferredcites →https://doi.org/10.1016/j.jtho.2016.11.1364openalex-snapshot

P2.03b-082 AQP11 as a Novel Factor of Lung Cancer Cell Resistance to Cisplatin

inferredcites →https://doi.org/10.1016/j.mrrev.2011.05.002openalex-snapshot

Initial steps of metastasis: Cell invasion and endothelial transmigration

inferredcites →https://doi.org/10.1016/j.mvr.2007.12.003openalex-snapshot

Aquaporin 1 is required for hypoxia-inducible angiogenesis in human retinal vascular endothelial cells

inferredcites →https://doi.org/10.1016/j.neures.2006.08.003openalex-snapshot

Identification of a cell polarity-related protein, Lin-7B, as a binding partner for a Rho effector, Rhotekin, and their possible interaction in neurons

inferredcites →https://doi.org/10.1016/j.neuroscience.2004.05.044openalex-snapshot

Molecular mechanisms of brain tumor edema

inferredcites →https://doi.org/10.1016/j.neuroscience.2004.06.088openalex-snapshot

New insights into water transport and edema in the central nervous system from phenotype analysis of aquaporin-4 null mice

inferredcites →https://doi.org/10.1016/j.neuroscience.2009.09.020openalex-snapshot

Water permeability through aquaporin-4 is regulated by protein kinase C and becomes rate-limiting for glioma invasion

inferredcites →https://doi.org/10.1016/j.prp.2017.11.006openalex-snapshot

Aquaporin-1 and -5 are involved in the invasion and proliferation of soft tissue sarcomas

inferredcites →https://doi.org/10.1016/j.redox.2019.101326openalex-snapshot

Human aquaporin-11 guarantees efficient transport of H2O2 across the endoplasmic reticulum membrane

inferredcites →https://doi.org/10.1016/j.sbi.2015.08.004openalex-snapshot

Structural insights into aquaporin selectivity and regulation

inferredcites →https://doi.org/10.1016/j.taap.2012.08.005openalex-snapshot

Mitochondrial aquaporin-8 knockdown in human hepatoma HepG2 cells causes ROS-induced mitochondrial depolarization and loss of viability

inferredcites →https://doi.org/10.1016/j.yexcr.2007.01.023openalex-snapshot

Filopodia are induced by aquaporin-9 expression

inferredcites →https://doi.org/10.1016/j.ygyno.2005.08.054openalex-snapshot

Expression and localization of aquaporin-5 in the epithelial ovarian tumors

inferredcites →https://doi.org/10.1016/s0014-5793(02)03581-0openalex-snapshot

New potent inhibitors of aquaporins: silver and gold compounds inhibit aquaporins of plant and human origin

inferredcites →https://doi.org/10.1016/s0021-9258(18)82322-5openalex-snapshot

The human aquaporin-CHIP gene. Structure, organization, and chromosomal localization

inferredcites →https://doi.org/10.1016/s0026-895x(24)26424-5openalex-snapshot

Cloned Human Aquaporin-1 Is a Cyclic GMP-Gated Ion Channel

inferredcites →https://doi.org/10.1016/s1095-6433(01)00429-9openalex-snapshot

The cytoskeleton and cell volume regulation

inferredcites →https://doi.org/10.1016/s1474-4422(12)70133-3openalex-snapshot

Aquaporin 4 and neuromyelitis optica

inferredcites →https://doi.org/10.1017/s1740925x06000044openalex-snapshot

A role for ion channels in glioma cell invasion

inferredcites →https://doi.org/10.1023/a:1023003616848openalex-snapshot

Membrane anchored serine proteases: A rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer

inferredcites →https://doi.org/10.1038/35000025openalex-snapshot

The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression

inferredcites →https://doi.org/10.1038/35052073openalex-snapshot

Untangling the ErbB signalling network

inferredcites →https://doi.org/10.1038/35099066openalex-snapshot

Transmembrane crosstalk between the extracellular matrix and the cytoskeleton

inferredcites →https://doi.org/10.1038/72256openalex-snapshot

Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke

inferredcites →https://doi.org/10.1038/cr.2009.5openalex-snapshot

TGF-β-induced epithelial to mesenchymal transition

inferredcites →https://doi.org/10.1038/nature03460openalex-snapshot

Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption

inferredcites →https://doi.org/10.1038/nature06196openalex-snapshot

Identification of stem cells in small intestine and colon by marker gene Lgr5

inferredcites →https://doi.org/10.1038/nature07602openalex-snapshot

Crypt stem cells as the cells-of-origin of intestinal cancer

inferredcites →https://doi.org/10.1038/nature10408openalex-snapshot

A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable

inferredcites →https://doi.org/10.1038/nature12930openalex-snapshot

Alveolar progenitor and stem cells in lung development, renewal and cancer

inferredcites →https://doi.org/10.1038/nature13480openalex-snapshot

Comprehensive molecular characterization of gastric adenocarcinoma

inferredcites →https://doi.org/10.1038/nature14863openalex-snapshot

Self-renewing diploid Axin2+ cells fuel homeostatic renewal of the liver

inferredcites →https://doi.org/10.1038/nature14966openalex-snapshot

Single-cell messenger RNA sequencing reveals rare intestinal cell types

inferredcites →https://doi.org/10.1038/nature23642openalex-snapshot

Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis

inferredcites →https://doi.org/10.1038/ncb1616openalex-snapshot

Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion

inferredcites →https://doi.org/10.1038/nrc1075openalex-snapshot

Tumour-cell invasion and migration: diversity and escape mechanisms

inferredcites →https://doi.org/10.1038/nrc1647openalex-snapshot

The role of focal-adhesion kinase in cancer — a new therapeutic opportunity

inferredcites →https://doi.org/10.1038/nrd4226openalex-snapshot

Aquaporins: important but elusive drug targets

inferredcites →https://doi.org/10.1038/nrm2786openalex-snapshot

Non-muscle myosin II takes centre stage in cell adhesion and migration

inferredcites →https://doi.org/10.1038/nrm763openalex-snapshot

Matrix metalloproteinases: a tail of a frog that became a prince

inferredcites →https://doi.org/10.1038/s41420-018-0113-yopenalex-snapshot

Estrogen nuclear receptors affect cell migration by altering sublocalization of AQP2 in glioma cell lines

inferredcites →https://doi.org/10.1038/s41467-018-06368-xopenalex-snapshot

Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo

inferredcites →https://doi.org/10.1038/s41583-021-00454-8openalex-snapshot

Molecular mechanisms of brain water transport

inferredcites →https://doi.org/10.1038/s41583-021-00514-zopenalex-snapshot

Aquaporin 4 and glymphatic flow have central roles in brain fluid homeostasis

inferredcites →https://doi.org/10.1038/s41598-019-56814-zopenalex-snapshot

Water channel pore size determines exclusion properties but not solute selectivity

inferredcites →https://doi.org/10.1038/sj.bjc.6600512openalex-snapshot

Increased aquaporin 1 water channel expression inhuman brain tumours

inferredcites →https://doi.org/10.1038/sj.bjc.6601644openalex-snapshot

ERK1/2 is activated in non-small-cell lung cancer and associated with advanced tumours

inferredcites →https://doi.org/10.1038/sj.bjc.6605093openalex-snapshot

Inhibition of the aquaporin 3 water channel increases the sensitivity of prostate cancer cells to cryotherapy

inferredcites →https://doi.org/10.1038/sj.onc.1206762openalex-snapshot

Involvement of aquaporins in colorectal carcinogenesis

inferredcites →https://doi.org/10.1038/srep07789openalex-snapshot

Mitochondrial aquaporin-8-mediated hydrogen peroxide transport is essential for teleost spermatozoon motility

inferredcites →https://doi.org/10.1038/srep40411openalex-snapshot

Significance of oxygen transport through aquaporins

inferredcites →https://doi.org/10.1039/c0dt01816copenalex-snapshot

Ruthenium anticancer compounds: myths and realities of the emerging metal-based drugs

inferredcites →https://doi.org/10.1042/bsr20171687openalex-snapshot

Significance of aquaporins’ expression in the prognosis of gastric cancer

inferredcites →https://doi.org/10.1042/bsr20180108openalex-snapshot

Prognostic values of aquaporins mRNA expression in human ovarian cancer

inferredcites →https://doi.org/10.1046/j.1365-2141.2001.02738.xopenalex-snapshot

Microvessel overexpression of aquaporin 1 parallels bone marrow angiogenesis in patients with active multiple myeloma

inferredcites →https://doi.org/10.1053/j.gastro.2016.09.018openalex-snapshot

Identification of Stem Cells in the Epithelium of the Stomach Corpus and Antrum of Mice

inferredcites →https://doi.org/10.1073/pnas.092131899openalex-snapshot

Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9

inferredcites →https://doi.org/10.1073/pnas.1005776107openalex-snapshot

Aquaporin-3 mediates hydrogen peroxide uptake to regulate downstream intracellular signaling

inferredcites →https://doi.org/10.1073/pnas.1210662109openalex-snapshot

Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction

inferredcites →https://doi.org/10.1073/pnas.241508198openalex-snapshot

Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein

inferredcites →https://doi.org/10.1074/jbc.272.33.20782openalex-snapshot

Cloning and Functional Expression of a New Water Channel Abundantly Expressed in the Testis Permeable to Water, Glycerol, and Urea

inferredcites →https://doi.org/10.1074/jbc.c400595200openalex-snapshot

The Inner Mitochondrial Membrane Has Aquaporin-8 Water Channels and Is Highly Permeable to Water

inferredcites →https://doi.org/10.1074/jbc.c800074200openalex-snapshot

The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional Repressors ZEB1 and ZEB2

inferredcites →https://doi.org/10.1074/jbc.m115.646034openalex-snapshot

Identification and Molecular Mechanisms of the Rapid Tonicity-induced Relocalization of the Aquaporin 4 Channel

inferredcites →https://doi.org/10.1074/jbc.m506591200openalex-snapshot

Radiation-induced Epidermal Growth Factor Receptor Nuclear Import Is Linked to Activation of DNA-dependent Protein Kinase

inferredcites →https://doi.org/10.1080/00313020701329914openalex-snapshot

The role of epithelial-mesenchymal transition in cancer pathology

inferredcites →https://doi.org/10.1083/jcb.120.2.371openalex-snapshot

CHIP28 water channels are localized in constitutively water-permeable segments of the nephron.

inferredcites →https://doi.org/10.1084/jem.20112398openalex-snapshot

Chemokine-dependent T cell migration requires aquaporin-3–mediated hydrogen peroxide uptake

inferredcites →https://doi.org/10.1088/1361-6463/aaae7aopenalex-snapshot

Atomic scale simulation of H 2 O 2 permeation through aquaporin: toward the understanding of plasma cancer treatment

inferredcites →https://doi.org/10.1089/ars.2013.5330openalex-snapshot

Tyrosine Kinase Signal Modulation: A Matter of H 2 O 2 Membrane Permeability?

inferredcites →https://doi.org/10.1089/ars.2016.6636openalex-snapshot

Stress Regulates Aquaporin-8 Permeability to Impact Cell Growth and Survival

inferredcites →https://doi.org/10.1089/dna.2009.1014openalex-snapshot

The Role of the Hypoxia-Inducible Factor 1 Binding Site in the Induction of Aquaporin-1 mRNA Expression by Hypoxia

inferredcites →https://doi.org/10.1089/scd.2013.0185openalex-snapshot

Aqp1 Enhances Migration of Bone Marrow Mesenchymal Stem Cells Through Regulation of FAK and β-Catenin

inferredcites →https://doi.org/10.1091/mbc.e08-05-0506openalex-snapshot

Snail and Slug Promote Epithelial-Mesenchymal Transition through β-Catenin–T-Cell Factor-4-dependent Expression of Transforming Growth Factor-β3

inferredcites →https://doi.org/10.1093/brain/awab311openalex-snapshot

Emerging roles for dynamic aquaporin-4 subcellular relocalization in CNS water homeostasis

inferredcites →https://doi.org/10.1096/fj.04-1723fjeopenalex-snapshot

Aquaporin‐4 facilitates reabsorption of excess fluid in vasogenic brain edema

inferredcites →https://doi.org/10.1096/fj.04-3281fjeopenalex-snapshot

New possible roles for aquaporin‐4 in astrocytes: cell cytoskeleton and functional relationship with connexin43

inferredcites →https://doi.org/10.1096/fj.06-5930fjeopenalex-snapshot

Increased migration and metastatic potential of tumor cells expressing aquaporin water channels

inferredcites →https://doi.org/10.1096/fj.13-245621openalex-snapshot

Aquaporin‐1 gene deletion reduces breast tumor growth and lung metastasis in tumor‐producing MMTV‐PyVT mice

inferredcites →https://doi.org/10.1097/00004647-200204000-00001openalex-snapshot

Aquaporins in Brain: Distribution, Physiology, and Pathophysiology

inferredcites →https://doi.org/10.1111/febs.12653openalex-snapshot

Structural determinants of the hydrogen peroxide permeability of aquaporins

inferredcites →https://doi.org/10.1111/j.1349-7006.2011.01927.xopenalex-snapshot

Critical role of aquaporin 3 on growth of human esophageal and oral squamous cell carcinoma

inferredcites →https://doi.org/10.1111/j.1365-2559.2011.04165.xopenalex-snapshot

Expression of aquaporin3 in human neoplastic tissues

inferredcites →https://doi.org/10.1111/j.1525-1438.2006.00476.xopenalex-snapshot

The influence of aquaporin-1 and microvessel density on ovarian carcinogenesis and ascites formation

inferredcites →https://doi.org/10.1113/expphysiol.2014.078527openalex-snapshot

Aquaporin 3 knockdown suppresses tumour growth and angiogenesis in experimental non‐small cell lung cancer

inferredcites →https://doi.org/10.1124/mol.115.101618openalex-snapshot

Bumetanide Derivatives AqB007 and AqB011 Selectively Block the Aquaporin-1 Ion Channel Conductance and Slow Cancer Cell Migration

inferredcites →https://doi.org/10.1126/science.1080405openalex-snapshot

Peroxiredoxin Evolution and the Regulation of Hydrogen Peroxide Signaling

inferredcites →https://doi.org/10.1126/science.1092053openalex-snapshot

Cell Migration: Integrating Signals from Front to Back

inferredcites →https://doi.org/10.1126/science.1130481openalex-snapshot

H 2 O 2 , a Necessary Evil for Cell Signaling

inferredcites →https://doi.org/10.1126/science.1248012openalex-snapshot

An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

inferredcites →https://doi.org/10.1126/science.296.5573.1652openalex-snapshot

Integrin Connections Map: To Infinity and Beyond

inferredcites →https://doi.org/10.1126/scisignal.2004815openalex-snapshot

BRAF Inhibitors Induce Metastasis in RAS Mutant or Inhibitor-Resistant Melanoma Cells by Reactivating MEK and ERK Signaling

inferredcites →https://doi.org/10.1128/mcb.00971-15openalex-snapshot

Aquaporin-3 Controls Breast Cancer Cell Migration by Regulating Hydrogen Peroxide Transport and Its Downstream Cell Signaling

inferredcites →https://doi.org/10.1128/mcb.01482-07openalex-snapshot

Prevention of Skin Tumorigenesis and Impairment of Epidermal Cell Proliferation by Targeted Aquaporin-3 Gene Disruption

inferredcites →https://doi.org/10.1136/gutjnl-2013-306508openalex-snapshot

The stem cell organisation, and the proliferative and gene expression profile of Barrett's epithelium, replicates pyloric-type gastric glands

inferredcites →https://doi.org/10.1136/jnnp.72.2.262openalex-snapshot

Aquaporin-4 expression is increased in oedematous human brain tumours

inferredcites →https://doi.org/10.1146/annurev.biophys.093008.131228openalex-snapshot

Eukaryotic Chemotaxis: A Network of Signaling Pathways Controls Motility, Directional Sensing, and Polarity

inferredcites →https://doi.org/10.1146/annurev.ph.58.030196.003155openalex-snapshot

Pathophysiology of the Aquaporin Water Channels

inferredcites →https://doi.org/10.1152/ajpcell.00033.2013openalex-snapshot

Relative CO2/NH3 selectivities of mammalian aquaporins 0–9

inferredcites →https://doi.org/10.1152/ajpcell.1997.273.5.c1562openalex-snapshot

Aqp1 expression in erythroleukemia cells: genetic regulation of glucocorticoid and chemical induction

inferredcites →https://doi.org/10.1152/ajpheart.1998.275.1.h234openalex-snapshot

Aquaporin-1 and endothelial nitric oxide synthase expression in capillary endothelia of human peritoneum

inferredcites →https://doi.org/10.1152/ajplung.2000.279.6.l1005openalex-snapshot

Reactive oxygen species in cell signaling

inferredcites →https://doi.org/10.1152/ajprenal.1997.272.5.f587openalex-snapshot

Evidence that aquaporin-1 mediates NaCl-induced water flux across descending vasa recta

inferredcites →https://doi.org/10.1152/ajprenal.2000.278.1.f13openalex-snapshot

Structure and function of aquaporin water channels

inferredcites →https://doi.org/10.1155/2015/286719openalex-snapshot

Blockade of Aquaporin 1 Inhibits Proliferation, Motility, and Metastatic Potential of MesotheliomaIn Vitrobut not in anIn VivoModel

inferredcites →https://doi.org/10.1158/0008-5472.can-19-2269openalex-snapshot

Aquaporin-7 Regulates the Response to Cellular Stress in Breast Cancer

inferredcites →https://doi.org/10.1159/000025674openalex-snapshot

Aquaporin-1 Is Expressed by Vascular Smooth Muscle Cells and Mediates Rapid Water Transport across Vascular Cell Membranes

inferredcites →https://doi.org/10.1159/000330082openalex-snapshot

Integrin Signaling Modulates AQP2 Trafficking via Arg-Gly-Asp (RGD) Motif

inferredcites →https://doi.org/10.1159/000337608openalex-snapshot

Hypoxia-induced Up-regulation of Aquaporin-1 Protein in Prostate Cancer Cells in a p38-dependent Manner

inferredcites →https://doi.org/10.1159/000369073openalex-snapshot

Expression of Aquaporin-1, Aquaporin-3, and Aquaporin-5 Correlates with Nodal Metastasis in Colon Cancer

inferredcites →https://doi.org/10.1170/t750openalex-snapshot

In vivo silencing of aquaporin-1 by RNA interference inhibits angiogenesis in the chick embryo chorioallantoic membrane assay.

inferredcites →https://doi.org/10.1172/jci39104openalex-snapshot

The basics of epithelial-mesenchymal transition

inferredcites →https://doi.org/10.1172/jci68782openalex-snapshot

Type 2 alveolar cells are stem cells in adult lung

inferredcites →https://doi.org/10.1172/jci8214openalex-snapshot

Requirement of aquaporin-1 for NaCl-driven water transport across descending vasa recta

inferredcites →https://doi.org/10.1177/1535370219826031openalex-snapshot

Role of genomic instability in human carcinogenesis

inferredcites →https://doi.org/10.1186/1477-7819-10-242openalex-snapshot

Expression of AQP5 and AQP8 in human colorectal carcinoma and their clinical significance

inferredcites →https://doi.org/10.1186/1477-7819-12-284openalex-snapshot

Over-expression of a poor prognostic marker in prostate cancer: AQP5 promotes cells growth and local invasion

inferredcites →https://doi.org/10.1186/1756-9966-30-86openalex-snapshot

Aquaporin-3 positively regulates matrix metalloproteinases via PI3K/AKT signal pathway in human gastric carcinoma SGC7901 cells

inferredcites →https://doi.org/10.1186/s12967-015-0439-7openalex-snapshot

Aquaporins as diagnostic and therapeutic targets in cancer: How far we are?

inferredcites →https://doi.org/10.1189/jlb.2ab0116-045ropenalex-snapshot

AQP8 transports NOX2-generated H2O2 across the plasma membrane to promote signaling in B cells

inferredcites →https://doi.org/10.1201/b19017-13openalex-snapshot

Aquaporins in Carcinogenesis: Water and Glycerol Channels as New Potential Drug Targets

inferredcites →https://doi.org/10.1210/jc.2011-0426openalex-snapshot

Identification of Estrogen Response Element in the Aquaporin-2 Gene That Mediates Estrogen-Induced Cell Migration and Invasion in Human Endometrial Carcinoma

inferredcites →https://doi.org/10.1242/dev.037317openalex-snapshot

The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells

inferredcites →https://doi.org/10.1242/jcs.02519openalex-snapshot

More than just water channels: unexpected cellular roles of aquaporins

inferredcites →https://doi.org/10.1242/jcs.110.6.707openalex-snapshot

Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages

inferredcites →https://doi.org/10.1258/ebm.2009.009181openalex-snapshot

Targeting epidermal growth factor receptor in head and neck cancer: lessons learned from cetuximab

inferredcites →https://doi.org/10.1371/journal.pone.0002162openalex-snapshot

Expression of Aquaporin 5 (AQP5) Promotes Tumor Invasion in Human Non Small Cell Lung Cancer

inferredcites →https://doi.org/10.1371/journal.pone.0006167openalex-snapshot

AQP1 Is Not Only a Water Channel: It Contributes to Cell Migration through Lin7/Beta-Catenin

inferredcites →https://doi.org/10.1371/journal.pone.0028385openalex-snapshot

Functional and Transcriptional Induction of Aquaporin-1 Gene by Hypoxia; Analysis of Promoter and Role of Hif-1α

inferredcites →https://doi.org/10.1371/journal.pone.0028492openalex-snapshot

Aquaporin-5: A Marker Protein for Proliferation and Migration of Human Breast Cancer Cells

inferredcites →https://doi.org/10.14712/fb2016062030131openalex-snapshot

Down-regulation of AQP4 Inhibits Proliferation, Migration and Invasion of Human Breast Cancer Cells

inferredcites →https://doi.org/10.1681/asn.2005080846openalex-snapshot

Aquaporin-1 Facilitates Epithelial Cell Migration in Kidney Proximal Tubule

inferredcites →https://doi.org/10.2174/138945007782151342openalex-snapshot

The Water Channels, New Druggable Targets to Combat Cancer Cell Survival,Invasiveness and Metastasis

inferredcites →https://doi.org/10.2353/ajpath.2006.050596openalex-snapshot

Aquaporin 1 Is Overexpressed in Lung Cancer and Stimulates NIH-3T3 Cell Proliferation and Anchorage-Independent Growth

inferredcites →https://doi.org/10.2353/ajpath.2008.071198openalex-snapshot

Role of Human Aquaporin 5 In Colorectal Carcinogenesis

inferredcites →https://doi.org/10.2741/3877openalex-snapshot

Hepatocyte aquaporins in bile formation and cholestasis

inferredcites →https://doi.org/10.3389/fphar.2014.00199openalex-snapshot

Aquaporins with anion/monocarboxylate permeability: mechanisms, relevance for pathogen–host interactions

inferredcites →https://doi.org/10.3390/cells9061403openalex-snapshot

Aquaporin-11 Contributes to TGF-β1-induced Endoplasmic Reticulum Stress in Human Visceral Adipocytes: Role in Obesity-Associated Inflammation

showing the first 200 of 217 · page through all 217

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4671653openalex-extracted

Diagnostic Gene and Immune Infiltration Analysis of Colorectal Cancer Based on Bioinformatics and Machine Learning

inferred← citeshttps://doi.org/10.1002/cnr2.70570openalex-snapshot

Virtual Screening of Traditional Chinese Medicine Natural Product Inhibitors Targeting AQP1 for Bladder Cancer

inferred← citeshttps://doi.org/10.1002/cnx2.70013openalex-snapshot

Pan‐Cancer Analysis of the Prognostic and Immunological Role of AQP9: Friend or Foe?

inferred← citeshttps://doi.org/10.1007/s00018-025-05801-xopenalex-snapshot

Aquaglyceroporin-7 ameliorates sorafenib resistance and immune evasion in hepatocellular carcinoma through inhibition of lipid accumulation

inferred← citeshttps://doi.org/10.1007/s00232-026-00375-6openalex-snapshot

Rapid Single-cell Measurement of Transient Transmembrane Water Flow under Osmotic Gradient

inferred← citeshttps://doi.org/10.1007/s13353-024-00843-6openalex-snapshot

Uncovering the role of aquaporin and chromobox family members as potential biomarkers in head and neck squamous cell carcinoma via integrative multiomics and in silico approach

inferred← citeshttps://doi.org/10.1016/b978-0-12-815389-5.00077-0openalex-snapshot

Intracellular pH homeostasis

inferred← citeshttps://doi.org/10.1016/j.anireprosci.2025.107956openalex-snapshot

Aquaporins in bovine male reproductive tract: From calves to reproductive bulls

inferred← citeshttps://doi.org/10.1016/j.ccr.2023.215507openalex-snapshot

Beyond cisplatin: New frontiers in metallodrugs for hard-to-treat triple negative breast cancer

inferred← citeshttps://doi.org/10.1016/j.ccr.2025.217354openalex-snapshot

Golden keys to inflammation: decoding the anti-inflammatory mechanisms of gold(I) and gold(III) complexes (2010–present)

inferred← citeshttps://doi.org/10.1016/j.compbiomed.2025.111336openalex-snapshot

Dynamic interplay at the gates: All-Atom simulations reveal isoform-specific aquaporin 7 inhibition

inferred← citeshttps://doi.org/10.1016/j.dld.2022.12.016openalex-snapshot

Aquaporin 1 is a prognostic marker and inhibits tumour progression through downregulation of Snail expression in intrahepatic cholangiocarcinoma

inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2023.10.405openalex-snapshot

Effects of cold atmospheric-pressure plasma in combination with doxorubicin drug against breast cancer cells in vitro and in vivo

inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e39402openalex-snapshot

Downregulation of aquaporins and PI3K/AKT and upregulation of PTEN expression induced by the flavone scutellarein in human colon cancer cell lines

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.145655openalex-snapshot

Aquaporin 9 promotes LPS-induced Eustachian tube inflammation through PP2A/NF-κB pathway

inferred← citeshttps://doi.org/10.1016/j.ijpharm.2026.126753openalex-snapshot

High viscosity microenvironment induces chemoresistance of cancer cells through upregulating P-gp

inferred← citeshttps://doi.org/10.1016/j.mri.2025.110345openalex-snapshot

Advanced diffusion-weighted imaging-derived quantitative parameters as biomarkers of fibrosarcoma-cell proliferation in nude mice: A study based on precise imaging-pathology correlation

inferred← citeshttps://doi.org/10.1016/j.wneu.2023.04.010openalex-snapshot

Aquaporin-4 as a New Potential Molecular Biomarker for Prognosis of Low-Grade Glioma: Comprehensive Analysis Based on Online Platforms

inferred← citeshttps://doi.org/10.1038/s41540-024-00354-4openalex-snapshot

Data-driven energy landscape reveals critical genes in cancer progression

inferred← citeshttps://doi.org/10.1038/s41598-024-74055-7openalex-snapshot

Markers of low field NMR relaxation features of tissues

inferred← citeshttps://doi.org/10.1038/s41598-025-25528-wopenalex-snapshot

Transcriptome study exploring the mechanisms linking pollutants and breast cancer aggressiveness

inferred← citeshttps://doi.org/10.1038/s41598-025-95513-wopenalex-snapshot

Aquaporin 9 downregulation in KRASG12V colorectal cancer and associated with increased proliferation and decreased apoptosis in cancer cells

inferred← citeshttps://doi.org/10.1039/d4md00786gopenalex-snapshot

Distinctive roles of aquaporins and novel therapeutic opportunities against cancer

inferred← citeshttps://doi.org/10.1080/07853890.2025.2490830openalex-snapshot

Construction and validation of renal cell carcinoma tumor cell differentiation-related prognostic classification (RCC-TCDC): an integrated bioinformatic analysis and clinical study

inferred← citeshttps://doi.org/10.1080/08957959.2026.2641618openalex-snapshot

Future perspectives of high pressure bioscience and biotechnology

inferred← citeshttps://doi.org/10.1080/14728222.2026.2619758openalex-snapshot

AQP7 suppresses cell stemness and metastasis by targeting Wnt signaling in basal-like breast cancer

inferred← citeshttps://doi.org/10.1080/1744666x.2025.2501718openalex-snapshot

AQP9 weakens the cytotoxicity of CD8 + T cells in colon adenocarcinoma by boosting M2 polarization of macrophages under hypoxia conditions

inferred← citeshttps://doi.org/10.1093/biolre/ioad097openalex-snapshot

Aquaporin 9 causes recurrent spontaneous abortion by inhibiting trophoblast cell epithelial-mesenchymal transformation and invasion through the PI3K/AKT pathway

inferred← citeshttps://doi.org/10.1093/chemse/bjad030openalex-snapshot

Ablation of AQP5 gene in mice leads to olfactory dysfunction caused by hyposecretion of Bowman’s gland

inferred← citeshttps://doi.org/10.1093/nar/gkaf1486openalex-snapshot

Stability of non-canonical nucleic acid structure as a potential modulator of cell fate

inferred← citeshttps://doi.org/10.1093/neuonc/noad070openalex-snapshot

Short-term topiramate treatment prevents radiation-induced cytotoxic edema in preclinical models of breast-cancer brain metastasis

inferred← citeshttps://doi.org/10.1113/jp284155openalex-snapshot

Blockage of aquaporin‐3 peroxiporin activity by organogold compounds affects melanoma cell adhesion, proliferation and migration

inferred← citeshttps://doi.org/10.1152/ajpregu.00166.2023openalex-snapshot

Molecular basis of the unique osmoregulatory strategy in the inshore hagfish, Eptatretus burgeri

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Development of a prognostic risk model for colorectal cancer based on microsatellite stability-associated genes

inferred← citeshttps://doi.org/10.1186/s12943-025-02375-xopenalex-snapshot

Oxidative stress in cancer: from tumor and microenvironment remodeling to therapeutic frontiers

inferred← citeshttps://doi.org/10.1186/s12944-025-02727-yopenalex-snapshot

Aquaporins in lipid metabolism: functions and regulation in health and disease

inferred← citeshttps://doi.org/10.1186/s13023-023-02808-0openalex-snapshot

PAI1 inhibits the pathogenesis of primary focal hyperhidrosis by targeting CHRNA1

inferred← citeshttps://doi.org/10.2147/copd.s588363openalex-snapshot

Research Progress on the Mechanisms of High Mucus Secretion in the Airway: A Scoping Review

inferred← citeshttps://doi.org/10.21873/cgp.20401openalex-snapshot

Hepatocellular Carcinoma: Up-regulated Circular RNAs Which Mediate Efficacy in PreclinicalIn VivoModels

inferred← citeshttps://doi.org/10.29328/journal.apcr.1001037openalex-snapshot

Expression of Collagen VI, Anticollagenase, Laminin, MM9, Claudins 1 and 5, N and E Cadherins in Choroid Plexus Tumors

inferred← citeshttps://doi.org/10.3389/fnins.2024.1349421openalex-snapshot

Homeostatic status of thyroid hormones and brain water movement as determinant factors in biology of cerebral gliomas: a pilot study using a bioinformatics approach

inferred← citeshttps://doi.org/10.3389/fonc.2022.963483openalex-snapshot

Screening of possible biomarkers and therapeutic targets in kidney renal clear cell carcinoma: Evidence from bioinformatic analysis

inferred← citeshttps://doi.org/10.3389/fonc.2024.1409627openalex-snapshot

Biomarkers of lymph node metastasis in colorectal cancer: update

inferred← citeshttps://doi.org/10.3389/pore.2023.1611179openalex-snapshot

Expression of aquaporin 1, 3 and 5 in colorectal carcinoma: correlation with clinicopathological characteristics and prognosis

inferred← citeshttps://doi.org/10.3390/biom15040488openalex-snapshot

The Association of Aquaporins with MAPK Signaling Pathway Unveils Potential Prognostic Biomarkers for Pancreatic Cancer: A Transcriptomics Approach

inferred← citeshttps://doi.org/10.3390/biomedicines13010134openalex-snapshot

A Narrative Review of Prognostic Gene Signatures in Oral Squamous Cell Carcinoma Using LASSO Cox Regression

inferred← citeshttps://doi.org/10.3390/biomedicines13123000openalex-snapshot

Rhapontigenin Suppresses Leptin-Induced Vasculogenic Mimicry by Inhibiting STAT3-Aquaporin-1 Axis in TNBC Cells

inferred← citeshttps://doi.org/10.3390/cells12030468openalex-snapshot

The Role of Aquaporin 5 (AQP5) in Lung Adenocarcinoma: A Review Article

inferred← citeshttps://doi.org/10.3390/cells12172170openalex-snapshot

Insights into the Function of Aquaporins in Gastrointestinal Fluid Absorption and Secretion in Health and Disease

inferred← citeshttps://doi.org/10.3390/cimb46030153openalex-snapshot

Deciphering Glioblastoma: Fundamental and Novel Insights into the Biology and Therapeutic Strategies of Gliomas

inferred← citeshttps://doi.org/10.3390/curroncol33010037openalex-snapshot

Discovery of a Ferroptosis-Related lncRNA–miRNA–mRNA Gene Signature in Endometrial Cancer Through a Comprehensive Co-Expression Network Analysis

inferred← citeshttps://doi.org/10.3390/genes14091694openalex-snapshot

Aquaporins Transcripts with Potential Prognostic Value in Pancreatic Cancer

inferred← citeshttps://doi.org/10.3390/ijms23158799openalex-snapshot

A Comprehensive Prognostic Analysis of Tumor-Related Blood Group Antigens in Pan-Cancers Suggests That SEMA7A as a Novel Biomarker in Kidney Renal Clear Cell Carcinoma

inferred← citeshttps://doi.org/10.3390/ijms231911634openalex-snapshot

Physiological Cooperation between Aquaporin 5 and TRPV4

inferred← citeshttps://doi.org/10.3390/ijms25126658openalex-snapshot

Peroxiporins in Triple-Negative Breast Cancer: Biomarker Potential and Therapeutic Perspectives

inferred← citeshttps://doi.org/10.3390/ijms26031330openalex-snapshot

The Expanding Role of Aquaporin-1, Aquaporin-3 and Aquaporin-5 as Transceptors: Involvement in Cancer Development and Potential Druggability

inferred← citeshttps://doi.org/10.3390/ijms27073016openalex-snapshot

The Multifunctional Roles of Aquaporins in Tumors: Focusing on Metabolism, Migration, and Regulation of the Tumor Microenvironment

inferred← citeshttps://doi.org/10.3390/jcm13061523openalex-snapshot

Diagnosis of Skin Cancer: From the Researcher Bench to the Patient’s Bedside

inferred← citeshttps://doi.org/10.3390/ph16121697openalex-snapshot

Cranberry Proanthocyanidins Mitigate Reflux-Induced Transporter Dysregulation in an Esophageal Adenocarcinoma Model

inferred← citeshttps://doi.org/10.46810/tdfd.1496982openalex-snapshot

Maybe a New Target for Gliomas: AQP1

inferred← citeshttps://doi.org/10.52756/ijerr.2023.v34spl.007openalex-snapshot

Combinatorial impact of Chelerythrine and DADS in the restoration of liver physiology during carcinogenic exposure in mice (Mus musculus)

inferred← citeshttps://doi.org/10.55730/1300-0152.2670openalex-snapshot

SVM-DO: identification of tumor-discriminating mRNA signatures via support vectormachines supported by disease ontology

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Développement d’un outil pronostic et prédictif basé sur la détection des signatures électromagnétiques associées à des caractéristiques des cellules de cancer bronchique

inferred← citeshttps://doi.org/10.7287/peerj.16025v0.1/reviews/1openalex-snapshot

Peer Review #1 of "Identification of key genes and validation of key gene aquaporin 1 on Wilms’ tumor metastasis (v0.1)"

inferred← citeshttps://doi.org/10.7287/peerj.16025v0.1/reviews/2openalex-snapshot

Peer Review #2 of "Identification of key genes and validation of key gene aquaporin 1 on Wilms’ tumor metastasis (v0.1)"

inferred← citeshttps://doi.org/10.7287/peerj.16025v0.1/reviews/3openalex-snapshot

Peer Review #3 of "Identification of key genes and validation of key gene aquaporin 1 on Wilms’ tumor metastasis (v0.1)"

inferred← citeshttps://doi.org/10.7287/peerj.16025v0.2/reviews/1openalex-snapshot

Peer Review #1 of "Identification of key genes and validation of key gene aquaporin 1 on Wilms’ tumor metastasis (v0.2)"

inferred← citeshttps://doi.org/10.7287/peerj.16025v0.2/reviews/3openalex-snapshot

Peer Review #3 of "Identification of key genes and validation of key gene aquaporin 1 on Wilms’ tumor metastasis (v0.2)"

inferred← citeshttps://doi.org/10.7717/peerj.16025openalex-snapshot

Identification of key genes and validation of key gene aquaporin 1 on Wilms’ tumor metastasis

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.