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National Prescription Patterns of Antidepressants in the Treatment of Adults With Major Depression in the US Between 1996 and 2015: A Population Representative Survey Based Analysis

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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National Trends in the Treatment for Depression From 1998 to 2007
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Screening for Serious Mental Illness in the General Population
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Epidemiology of Major Depressive Disorder
inferredcites →https://doi.org/10.1001/jama.2009.1943openalex-snapshot
Antidepressant Drug Effects and Depression Severity
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The Epidemiology of Major Depressive Disorder
inferredcites →https://doi.org/10.1001/jamainternmed.2016.5057openalex-snapshot
Treatment of Adult Depression in the United States
inferredcites →https://doi.org/10.1001/jamapsychiatry.2017.4602openalex-snapshot
Epidemiology of Adult DSM-5 Major Depressive Disorder and Its Specifiers in the United States
inferredcites →https://doi.org/10.1001/jamapsychiatry.2019.0633openalex-snapshot
Trends in Treatment and Spending for Patients Receiving Outpatient Treatment of Depression in the United States, 1998-2015
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Outpatient utilization of antidepressants: A prescription database analysis
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Prescribing patterns of antidepressants in Europe: Results from the Factors Influencing Depression Endpoints Research (FINDER) study
inferredcites →https://doi.org/10.1016/s0140-6736(09)60046-5openalex-snapshot
Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis
inferredcites →https://doi.org/10.1016/s0140-6736(17)32802-7openalex-snapshot
Comparative Efficacy and Acceptability of 21 Antidepressant Drugs for the Acute Treatment of Adults With Major Depressive Disorder: A Systematic Review and Network Meta-Analysis
inferredcites →https://doi.org/10.1016/s2215-0366(19)30216-0openalex-snapshot
Influence of baseline severity on the effects of SSRIs in depression: an item-based, patient-level post-hoc analysis
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Optimal dose of selective serotonin reuptake inhibitors, venlafaxine, and mirtazapine in major depression: a systematic review and dose-response meta-analysis
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Short screening scales to monitor population prevalences and trends in non-specific psychological distress
inferredcites →https://doi.org/10.1093/ageing/afl023openalex-snapshot
Prevalence, duration and indications for prescribing of antidepressants in primary care
inferredcites →https://doi.org/10.1097/01.mlr.0000093487.78664.3copenalex-snapshot
The Patient Health Questionnaire-2
inferredcites →https://doi.org/10.1097/mlr.0b013e318195fa79openalex-snapshot
Sensitivity of Household Reported Medical Conditions in the Medical Expenditure Panel Survey
inferredcites →https://doi.org/10.1111/appy.12176openalex-snapshot
International study on antidepressant prescription pattern at 40 major psychiatric institutions and hospitals in A sia: A 10‐year comparison study
inferredcites →https://doi.org/10.1111/j.1440-1819.2007.01702.xopenalex-snapshot
International study on antidepressant prescription pattern at 20 teaching hospitals and major psychiatric institutions in East Asia: Analysis of 1898 cases from China, Japan, Korea, Singapore and Taiwan
inferredcites →https://doi.org/10.1136/bmj.b3999openalex-snapshot
Explaining the rise in antidepressant prescribing: a descriptive study using the general practice research database
inferredcites →https://doi.org/10.1136/bmjopen-2018-023222openalex-snapshot
Evidence synthesis, practice guidelines and real-world prescriptions of new generation antidepressants in the treatment of depression: a protocol for cumulative network meta-analyses and meta-epidemiological study
inferredcites →https://doi.org/10.1146/annurev-publhealth-031912-114409openalex-snapshot
The Epidemiology of Depression Across Cultures
inferredcites →https://doi.org/10.1176/ajp.150.4.1openalex-snapshot
Practice guideline for major depressive disorder in adults. American Psychiatric Association
inferredcites →https://doi.org/10.1176/ajp.157.1.1openalex-snapshot
Distributed Disturbances in Brain Structure and Function in Schizophrenia
inferredcites →https://doi.org/10.1176/ajp.2006.163.12.2141openalex-snapshot
Changes in the Prevalence of Major Depression and Comorbid Substance Use Disorders in the United States Between 1991–1992 and 2001–2002
inferredcites →https://doi.org/10.1177/0269881107088441openalex-snapshot
Evidence-based guidelines for treating depressive disorders with antidepressants: A revision of the 2000 British Association for Psychopharmacology guidelines
inferredcites →https://doi.org/10.1177/0269881115581093openalex-snapshot
Evidence-based guidelines for treating depressive disorders with antidepressants: A revision of the 2008 British Association for Psychopharmacology guidelines
inferredcites →https://doi.org/10.1192/bjp.168.2.164openalex-snapshot
The Treatment of Depression: Prescribing Patterns of Antidepressants in Primary Care in the UK
inferredcites →https://doi.org/10.1371/journal.pmed.1001547openalex-snapshot
Burden of Depressive Disorders by Country, Sex, Age, and Year: Findings from the Global Burden of Disease Study 2010
inferredcites →https://doi.org/10.4088/jcp.13m08443openalex-snapshot
National Trends in Long-Term Use of Antidepressant Medications
inferredcites →https://doi.org/10.4088/jcp.14m09298openalex-snapshot
The Economic Burden of Adults With Major Depressive Disorder in the United States (2005 and 2010)
inferredcites →https://doi.org/10.4088/jcp.v69n0704openalex-snapshot
National Patterns in Antidepressant Treatment by Psychiatrists and General Medical Providers
inferredcites →https://doi.org/10.4088/pcc.v03n0611openalex-snapshot
National Patterns of Medication Treatment for Depression, 1987 to 2001
inferredcites →https://doi.org/10.4103/0019-5545.105503openalex-snapshot
IPS multicentric study: Antidepressant prescription patterns
inferredcites →https://doi.org/10.4135/9781483349985.n242openalex-snapshot
Medical Expenditure Panel Survey (MEPS)

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1093/sxmrev/qeaf056openalex-snapshot
Can antidepressants compromise sperm quality? A comprehensive review of preclinical evidence
inferred← citeshttps://doi.org/10.1097/jcp.0000000000002025openalex-snapshot
What if STAR*D Had Been Placebo-Controlled? A Critical Reexamination of a Foundational Study in Depression Treatment
inferred← citeshttps://doi.org/10.1097/jcp.0000000000002068openalex-snapshot
Escitalopram-Associated Drug Rash
inferred← citeshttps://doi.org/10.1097/mnh.0000000000000633openalex-snapshot
Editorial: Management of cardiovascular risk factors and other comorbidities in chronic kidney disease
inferred← citeshttps://doi.org/10.1097/pra.0000000000000687openalex-snapshot
Mirtazapine-induced Acute Pancreatitis in Patients With Depression: A Systematic Review
inferred← citeshttps://doi.org/10.1097/yic.0000000000000534openalex-snapshot
Modulating factors in mood disorders treatment
inferred← citeshttps://doi.org/10.1098/rspb.2023.1273openalex-snapshot
Pharmaceutical pollution alters the cost of bacterial infection and its relationship to pathogen load
inferred← citeshttps://doi.org/10.1098/rstb.2022.0010openalex-snapshot
Can pharmaceutical pollution alter the spread of infectious disease? A case study using fluoxetine
inferred← citeshttps://doi.org/10.1101/2022.07.27.22277782openalex-snapshot
A Framework for Inferring and Analyzing Pharmacotherapy Treatment Patterns
inferred← citeshttps://doi.org/10.1101/2024.11.14.24317362openalex-snapshot
Trends in Prescription Fills for Blood Pressure-Elevating and Antihypertensive Medications, 2017–2023
inferred← citeshttps://doi.org/10.1111/acps.13275openalex-snapshot
Low SSRI dosing in clinical practice—a register‐based longitudinal study
inferred← citeshttps://doi.org/10.1111/appy.70017openalex-snapshot
Pharmacoepidemiologic Trends and Factors Associated With Use and Dosing of Newer Antidepressants in 8357 Patients Across Asia: A Two‐Decade Perspective
inferred← citeshttps://doi.org/10.1111/jcmm.71112openalex-snapshot
Exploring Molecular Mechanism of Fluoxetine in Animal Models of Depression via Integrated Metabolomic and Proteomic Analysis
inferred← citeshttps://doi.org/10.1111/jre.12939openalex-snapshot
Association of different antidepressant classes with clinical attachment level and alveolar bone loss in patients with periodontitis: A retrospective study
inferred← citeshttps://doi.org/10.1111/nyas.15112openalex-snapshot
Pharmacotherapy causing weight gain and metabolic alteration in those with obesity and obesity‐related conditions: A review
inferred← citeshttps://doi.org/10.1136/bmjment-2023-300730openalex-snapshot
Beneficial and harmful effects of tricyclic antidepressants for adults with major depressive disorder: a systematic review with meta-analysis and trial sequential analysis
inferred← citeshttps://doi.org/10.1136/bmjment-2023-300919openalex-snapshot
Estimating the smallest worthwhile difference of antidepressants: a cross-sectional survey
inferred← citeshttps://doi.org/10.1136/ebmental-2021-300418openalex-snapshot
Important adverse events to be evaluated in antidepressant trials and meta-analyses in depression: a large international preference study including patients and healthcare professionals
inferred← citeshttps://doi.org/10.1159/000520554openalex-snapshot
Dose-Response Relationship in Selective Serotonin and Norepinephrine Reuptake Inhibitors in the Treatment of Major Depressive Disorder: A Meta-Analysis and Network Meta-Analysis of Randomized Controlled Trials
inferred← citeshttps://doi.org/10.1159/000530084openalex-snapshot
Population Pharmacokinetic Modeling to Inform Sertraline Dosing Optimization in Patients with Depression
inferred← citeshttps://doi.org/10.1161/hypertensionaha.124.24316openalex-snapshot
Blood Pressure–Elevating and Antihypertensive Medication Prescription Trends
inferred← citeshttps://doi.org/10.1161/jaha.123.031281openalex-snapshot
Association of Depression and Adherence to Oral Anticoagulation in Patients With Atrial Fibrillation
inferred← citeshttps://doi.org/10.1177/00221678251388297openalex-snapshot
First-Person Psychopharmacology: This is Normal Care
inferred← citeshttps://doi.org/10.1177/02698811231224217openalex-snapshot
Interactions between classic psychedelics and serotonergic antidepressants: Effects on the acute psychedelic subjective experience, well-being and depressive symptoms from a prospective survey study
inferred← citeshttps://doi.org/10.1177/02698811241237870openalex-snapshot
Effects of discontinuation of serotonergic antidepressants prior to psilocybin therapy versus escitalopram for major depression
inferred← citeshttps://doi.org/10.1177/02698811251368360openalex-snapshot
Concomitant use of antidepressants and classic psychedelics: A scoping review
inferred← citeshttps://doi.org/10.1177/02698811261420087openalex-snapshot
A phase 2 uncontrolled, open-label study of intranasal BPL-003 (5-methoxy- N,N -dimethyltryptamine) in patients with treatment-resistant depression
inferred← citeshttps://doi.org/10.1177/07067437251322399openalex-snapshot
Personalising Antidepressant Treatment for Unipolar Depression Combining Individual Choices, Risks and big Data: The PETRUSHKA Tool: Personnalisation du traitement antidépresseur de la dépression unipolaire associant choix individuels, risques et mégadonnées: l’outil PETRUSHKA
inferred← citeshttps://doi.org/10.1177/08919887221090217openalex-snapshot
Depression After Parkinson’s Disease: Treated Differently or Not At All?
inferred← citeshttps://doi.org/10.1177/09246479251346445openalex-snapshot
SSRI antidepressants and perceived loss of lean muscle in men: A qualitative exploration of some online anecdotal concerns
inferred← citeshttps://doi.org/10.1177/10398562241308437openalex-snapshot
Deprescribing antidepressants: An integral and neglected component of high-quality prescribing practice
inferred← citeshttps://doi.org/10.1177/1877718x241296016openalex-snapshot
The effect of serotonin reuptake and serotonin-noradrenaline reuptake inhibitors on motor symptoms in Parkinson's disease: A PPMI-based matched-subject study
inferred← citeshttps://doi.org/10.1177/26331055241286518openalex-snapshot
Neuroimaging and the Investigation of Drug-Drug Interactions Involving Psychedelics
inferred← citeshttps://doi.org/10.1186/s12875-022-01769-wopenalex-snapshot
Trends in the epidemiology of depression and comorbidities from 2000 to 2019 in Belgium
inferred← citeshttps://doi.org/10.1186/s12888-025-06521-zopenalex-snapshot
Uncovering antidepressant prescription patterns: a three-year analysis of outpatient trends
inferred← citeshttps://doi.org/10.1186/s12888-026-07867-8openalex-snapshot
The evolution of SSRI research: trajectories of knowledge domains across four decades
inferred← citeshttps://doi.org/10.1186/s12911-024-02469-4openalex-snapshot
A framework for inferring and analyzing pharmacotherapy treatment patterns
inferred← citeshttps://doi.org/10.1186/s13722-025-00579-6openalex-snapshot
Pharmacotherapy of psychiatric inpatients with mental and behavioral disorders caused by sedatives or hypnotics (F13): Results from an observational pharmacovigilance program between 2000 and 2017
inferred← citeshttps://doi.org/10.1192/bjp.2021.165openalex-snapshot
Optimal dose of aripiprazole for augmentation therapy of antidepressant-refractory depression: preliminary findings based on a systematic review and dose–effect meta-analysis
inferred← citeshttps://doi.org/10.1192/bjp.2026.10719openalex-snapshot
Understanding antidepressant change patterns in the UK Biobank
inferred← citeshttps://doi.org/10.1248/bpb.b24-00083openalex-snapshot
Structure–Activity Relationship Analysis of Fluoxetine for Suppression of Inflammatory Cytokine Production
inferred← citeshttps://doi.org/10.1371/journal.pone.0287582openalex-snapshot
Understanding target-specific effects of antidepressant drug pollution on molluscs: A systematic review protocol
inferred← citeshttps://doi.org/10.1371/journal.pone.0318464openalex-snapshot
Public perception and changing attitudes toward antidepressants over a decade in social media: Lessons learned from online discussion using artificial intelligence
inferred← citeshttps://doi.org/10.1556/2054.2022.00211openalex-snapshot
Psychedelic assisted therapy for major depressive disorder: Recent work and clinical directions
inferred← citeshttps://doi.org/10.17816/medjrf675281openalex-snapshot
Effects of antidepressants on weight: mechanisms, clinical effects, and management strategies
inferred← citeshttps://doi.org/10.18203/2320-6012.ijrms20230870openalex-snapshot
Study of the prescription pattern of anti-depressants in a tertiary care hospital: a prospective observational study
inferred← citeshttps://doi.org/10.18553/jmcp.2026.32.7.793openalex-snapshot
Primary adherence to medications for the treatment of major depressive disorder: A descriptive study using real-world data
inferred← citeshttps://doi.org/10.21203/rs.3.rs-2282174/v1openalex-snapshot
An in-depth Analysis on Four Classes of Antidepressants Quantification from Human Serum using LC-MS/MS
inferred← citeshttps://doi.org/10.2147/ndt.s501207openalex-snapshot
Preclinical Evidence for the Use of Brexpiprazole + Antidepressant Treatment for Major Depressive Disorder and Post-Traumatic Stress Disorder: A Systematic Review
inferred← citeshttps://doi.org/10.2174/0118715273378214250213114328openalex-snapshot
Serotonergic Dynamics in Autism Spectrum Disorder: Unraveling the Intricate Connection
inferred← citeshttps://doi.org/10.2196/20920openalex-snapshot
Evaluating Behavioral and Linguistic Changes During Drug Treatment for Depression Using Tweets in Spanish: Pairwise Comparison Study
inferred← citeshttps://doi.org/10.2196/preprints.69023openalex-snapshot
Public perception and changing attitudes toward antidepressants over a decade in social media: lessons learned from online discussion using artificial intelligence (Preprint)
inferred← citeshttps://doi.org/10.22215/etd/2023-15485openalex-snapshot
Sex Differences in the Antidepressant Effects of Ketamine
inferred← citeshttps://doi.org/10.22371/07.2023.015openalex-snapshot
Measuring The Effectiveness of Antidepressant Treatment By Implementing Beck's Depression Inventory (BDI)
inferred← citeshttps://doi.org/10.2478/abm-2022-0008openalex-snapshot
Chirality of antidepressive drugs: an overview of stereoselectivity
inferred← citeshttps://doi.org/10.24869/psyd.2022.219openalex-snapshot
SEX-RELATED DIFFERENCES IN THE PHARMACOLOGICAL TREATMENT OF MAJOR DEPRESSION - ARE WOMEN AND MEN TREATED DIFFERENTLY?
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1184010openalex-snapshot
Serotonin transporter-deficient mice display enhanced adipose tissue inflammation after chronic high-fat diet feeding
inferred← citeshttps://doi.org/10.3389/fnhum.2022.1029256openalex-snapshot
Neural correlates of psychodynamic and non-psychodynamic therapies in different clinical populations through fMRI: A meta-analysis and systematic review
inferred← citeshttps://doi.org/10.3389/fnhum.2023.1225836openalex-snapshot
Perceived antidepressant efficacy associated with reduced negative and enhanced neutral mnemonic discrimination
inferred← citeshttps://doi.org/10.3389/fnmol.2022.947192openalex-snapshot
Depression in Adolescence and Brain-Derived Neurotrophic Factor
inferred← citeshttps://doi.org/10.3389/fnut.2024.1464526openalex-snapshot
Effects of fish oil supplementation on bone turnover markers in depression: a pilot study
inferred← citeshttps://doi.org/10.3389/fonc.2022.939636openalex-snapshot
The incidence risk of breast and gynecological cancer by antidepressant use: A systematic review and dose–response meta-analysis of epidemiological studies involving 160,727 patients
inferred← citeshttps://doi.org/10.3389/fphar.2021.762738openalex-snapshot
Reviewing the Role of the Endocannabinoid System in the Pathophysiology of Depression
inferred← citeshttps://doi.org/10.3389/fphar.2022.893891openalex-snapshot
Trends in Brazilian market of antidepressants: A five-year dataset analysis
inferred← citeshttps://doi.org/10.3389/fphar.2022.967826openalex-snapshot
Trends in the utilization of psychotropic medications in China from 2018 to 2021
inferred← citeshttps://doi.org/10.3389/fphar.2025.1511936openalex-snapshot
Antidepressant use in the Canary Islands (Spain): a retrospective study of provincial, island and municipal trends and associated factors
inferred← citeshttps://doi.org/10.3389/fphar.2025.1536438openalex-snapshot
Impact of fluoxetine exposure on Lymnaea stagnalis and its developing eggs: integrating untargeted lipidomics, targeted metabolomics, and classical risk assessment
inferred← citeshttps://doi.org/10.3389/fphar.2025.1644241openalex-snapshot
Neurological adverse events associated with antidepressants: a comprehensive 22-year analysis of the FDA adverse event reporting system
inferred← citeshttps://doi.org/10.3389/fpsyt.2020.00605openalex-snapshot
To Overcome Psychiatric Patients’ Mind–Brain Dualism, Reifying the Mind Won’t Help
inferred← citeshttps://doi.org/10.3389/fpsyt.2021.581876openalex-snapshot
An Ecological Study of a Universal Employee Depression Awareness and Stigma Reduction Intervention: “Right Direction”
inferred← citeshttps://doi.org/10.3389/fpsyt.2025.1542000openalex-snapshot
Estimating the incidence of actionable drug-gene interactions in Japanese patients with major depressive disorder
inferred← citeshttps://doi.org/10.3389/fpsyt.2025.1645225openalex-snapshot
Toward precision psychiatry: theoretical implications of bimodal response patterns to vasopressin V1b receptor inhibition in depression
inferred← citeshttps://doi.org/10.3390/brainsci15020161openalex-snapshot
Emerging Medications for Treatment-Resistant Depression: A Review with Perspective on Mechanisms and Challenges
inferred← citeshttps://doi.org/10.3390/healthcare10050803openalex-snapshot
Antidepressants and Vertebral and Hip Risk Fracture: An Updated Systematic Review and Meta-Analysis
inferred← citeshttps://doi.org/10.3390/healthcare13192433openalex-snapshot
The Off-Label Use of Selective Serotonin Reuptake Inhibitors for Sexual Behavior Management: Risks and Considerations
inferred← citeshttps://doi.org/10.3390/ijerph18105094openalex-snapshot
Impacts of Psychopharmaceuticals on the Neurodevelopment of Aquatic Wildlife: A Call for Increased Knowledge Exchange across Disciplines to Highlight Implications for Human Health
inferred← citeshttps://doi.org/10.3390/ijerph18168596openalex-snapshot
Exploring Treatment for Depression in Parkinson’s Patients: A Cross-Sectional Analysis
inferred← citeshttps://doi.org/10.3390/ijms23105526openalex-snapshot
Modulation of Endocannabinoid System Components in Depression: Pre-Clinical and Clinical Evidence
inferred← citeshttps://doi.org/10.3390/ijms25084511openalex-snapshot
Mechanisms Involved in the Link between Depression, Antidepressant Treatment, and Associated Weight Change
inferred← citeshttps://doi.org/10.3390/ijms25147992openalex-snapshot
Biomarkers in the Diagnosis and Prediction of Medication Response in Depression and the Role of Nutraceuticals
inferred← citeshttps://doi.org/10.3390/jcm13154398openalex-snapshot
Advances in Psychotropic Treatment for Pregnant Women: Efficacy, Adverse Outcomes, and Therapeutic Monitoring
inferred← citeshttps://doi.org/10.3390/jpm11050406openalex-snapshot
Prescription Pattern of Antidepressants and the Potential for Personalized Medicine in the Qatari Population
inferred← citeshttps://doi.org/10.3390/ph15050565openalex-snapshot
A Focus on Abuse/Misuse and Withdrawal Issues with Selective Serotonin Reuptake Inhibitors (SSRIs): Analysis of Both the European EMA and the US FAERS Pharmacovigilance Databases
inferred← citeshttps://doi.org/10.3390/ph19020209openalex-snapshot
Influence of CYP2D6, CYP2C19, and CYP2C9 Pharmacogenetics and Clinical Factors on Dose-Normalized Venlafaxine/O-Desmethylvenlafaxine Metabolic Ratio in Spanish Patients
inferred← citeshttps://doi.org/10.3390/pharma4010006openalex-snapshot
Evaluating Major Bleeding Risks with Concomitant Use of Direct Oral Anticoagulants and Selective Serotonin Reuptake Inhibitors in Nonvalvular Atrial Fibrillation Patients
inferred← citeshttps://doi.org/10.3390/pharmacy12060174openalex-snapshot
Assessment of Potential Drug–Drug Interactions of Psycholeptics and Antidepressants in Outpatient Settings
inferred← citeshttps://doi.org/10.3390/toxics13121043openalex-snapshot
Understanding Target-Specific Effects of Antidepressant Drug Pollution on Molluscs: A Systematic Review Report
inferred← citeshttps://doi.org/10.4088/jcp.23m14845openalex-snapshot
Long-Term Safety and Efficacy of Initial and Repeat Treatment Courses With Zuranolone in Adult Patients With Major Depressive Disorder
inferred← citeshttps://doi.org/10.4103/njpt.njpt_28_23openalex-snapshot
Cost variance analysis of antidepressant drugs available in the Indian Pharmaceutical Market between January 2023 and March 2023
inferred← citeshttps://doi.org/10.5847/wjem.j.1920-8642.2023.104openalex-snapshot
Prevalence and risk factors for acquired long QT syndrome in the emergency department: a retrospective observational study
inferred← citeshttps://doi.org/10.61373/pp024r.0025openalex-snapshot
An estimate of the number of people with clinical depression eligible for psilocybin-assisted therapy in the United States
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