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Dietary supplementation of squalene increases the growth performance of early-weaned piglets by improving gut microbiota, intestinal barrier, and blood antioxidant capacity

https://doi.org/10.3389/fvets.2022.995548

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/mnfr.201400518openalex-snapshot

Dietary squalene supplementation improves DSS‐induced acute colitis by downregulating p38 MAPK and NFkB signaling pathways

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Current Insights into the Biological Action of Squalene

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Ussing Chamber Methods to Study the Esophageal Epithelial Barrier

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Western Blotting Using In-Gel Protein Labeling as a Normalization Control: Advantages of Stain-Free Technology

inferredcites →https://doi.org/10.1007/bf00500015openalex-snapshot

Effects of noradrenaline and somatostatin on basal and stimulated mucosal ion transport in the guinea-pig small intestine

inferredcites →https://doi.org/10.1007/s10753-019-01138-3openalex-snapshot

Pioglitazone Attenuates Experimental Colitis-Associated Hyperalgesia through Improving the Intestinal Barrier Dysfunction

inferredcites →https://doi.org/10.1007/s12603-018-1022-8openalex-snapshot

Glucagon-Like Peptide-2 Improve Intestinal Mucosal Barrier Function in Aged Rats

inferredcites →https://doi.org/10.1007/s13197-020-04955-9openalex-snapshot

Exploring the physical and quality attributes of muffins incorporated with microencapsulated squalene as a functional food additive

inferredcites →https://doi.org/10.1016/b978-0-12-416003-3.00014-7openalex-snapshot

Biological Importance and Applications of Squalene and Squalane

inferredcites →https://doi.org/10.1016/j.addr.2009.09.005openalex-snapshot

Squalene: A natural triterpene for use in disease management and therapy

inferredcites →https://doi.org/10.1016/j.cbi.2006.02.004openalex-snapshot

Attenuation of cyclophosphamide induced toxicity by squalene in experimental rats

inferredcites →https://doi.org/10.1016/j.fitote.2017.11.012openalex-snapshot

Activation of IGF-1/IGFBP-3 signaling by berberine improves intestinal mucosal barrier of rats with acute endotoxemia

inferredcites →https://doi.org/10.1016/j.jss.2006.04.028openalex-snapshot

IGF-1 Protects Intestinal Epithelial Cells From Oxidative Stress-Induced Apoptosis

inferredcites →https://doi.org/10.1016/j.psj.2020.08.042openalex-snapshot

Effects of graded levels of dietary squalene supplementation on the growth performance, plasma biochemical parameters, antioxidant capacity, and meat quality in broiler chickens

inferredcites →https://doi.org/10.1016/j.psj.2020.12.017openalex-snapshot

Dietary squalene supplementation alleviates diquat-induced oxidative stress and liver damage of broiler chickens

inferredcites →https://doi.org/10.1016/s2468-1253(17)30147-4openalex-snapshot

The microbiota–gut–brain axis in obesity

inferredcites →https://doi.org/10.1017/s0007114510005660openalex-snapshot

Intestinal barrier function and absorption in pigs after weaning: a review

inferredcites →https://doi.org/10.1021/acs.jafc.1c00865openalex-snapshot

Ovomucin Ameliorates Intestinal Barrier and Intestinal Bacteria to Attenuate DSS-Induced Colitis in Mice

inferredcites →https://doi.org/10.1038/130665b0openalex-snapshot

Constitution of Cholesterol

inferredcites →https://doi.org/10.1038/nri2653openalex-snapshot

Intestinal mucosal barrier function in health and disease

inferredcites →https://doi.org/10.1038/oby.2011.104openalex-snapshot

Validation of Ussing Chamber Technology to Study Satiety Hormone Release From Human Duodenal Specimens

inferredcites →https://doi.org/10.1038/s41579-020-0433-9openalex-snapshot

Gut microbiota in human metabolic health and disease

inferredcites →https://doi.org/10.1053/j.gastro.2020.04.077openalex-snapshot

Contribution of the Intestinal Microbiome and Gut Barrier to Hepatic Disorders

inferredcites →https://doi.org/10.1053/j.gastro.2020.07.003openalex-snapshot

High-Throughput Screen Identifies Host and Microbiota Regulators of Intestinal Barrier Function

inferredcites →https://doi.org/10.1093/jas/skaa067openalex-snapshot

Effects of dietary supplementation with exogenous catalase on growth performance, oxidative stress, and hepatic apoptosis in weaned piglets challenged with lipopolysaccharide

inferredcites →https://doi.org/10.1093/jas/sky104openalex-snapshot

Diquat-induced oxidative stress increases intestinal permeability, impairs mitochondrial function, and triggers mitophagy in piglets1

inferredcites →https://doi.org/10.1093/jn/134.9.2256openalex-snapshot

Weaning Induces Both Transient and Long-Lasting Modifications of Absorptive, Secretory, and Barrier Properties of Piglet Intestine

inferredcites →https://doi.org/10.1096/fj.202002086rropenalex-snapshot

Tetrandrine attenuates intestinal epithelial barrier defects caused by colitis through promoting the expression of Occludin via the AhR‐miR‐429 pathway

inferredcites →https://doi.org/10.1111/and.13117openalex-snapshot

Squalene is a potential endocrine modulator in rat: A proof-of-principle study with 3-methylcholanthrene-induced toxicity

inferredcites →https://doi.org/10.1126/sciadv.aaz5466openalex-snapshot

Squalene-based multidrug nanoparticles for improved mitigation of uncontrolled inflammation in rodents

inferredcites →https://doi.org/10.1136/gut.2008.165886openalex-snapshot

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

inferredcites →https://doi.org/10.1155/2014/361590openalex-snapshot

The Design of a Quantitative Western Blot Experiment

inferredcites →https://doi.org/10.1182/blood.2020005957openalex-snapshot

Glucagon-like peptide 2 for intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans

inferredcites →https://doi.org/10.1186/2049-1891-4-19openalex-snapshot

The biological stress of early weaned piglets

inferredcites →https://doi.org/10.1186/s12576-021-00817-xopenalex-snapshot

From digestion and absorption to innate immunity and health care: water and food intake may contribute to IL-22 in ILC3-dependent mucosal immunity in the jejunum

inferredcites →https://doi.org/10.1186/s13568-020-01130-3openalex-snapshot

Identification of microflora related to growth performance in pigs based on 16S rRNA sequence analyses

inferredcites →https://doi.org/10.1186/s40104-020-00460-3openalex-snapshot

Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets

inferredcites →https://doi.org/10.1186/s40168-021-01157-zopenalex-snapshot

Polyamine metabolism links gut microbiota and testicular dysfunction

inferredcites →https://doi.org/10.1371/journal.pone.0104224openalex-snapshot

Dietary Squalene Increases High Density Lipoprotein-Cholesterol and Paraoxonase 1 and Decreases Oxidative Stress in Mice

inferredcites →https://doi.org/10.1371/journal.pone.0111950openalex-snapshot

L-Glutamate Supplementation Improves Small Intestinal Architecture and Enhances the Expressions of Jejunal Mucosa Amino Acid Receptors and Transporters in Weaning Piglets

inferredcites →https://doi.org/10.1371/journal.pone.0218384openalex-snapshot

Antibiotics induced intestinal tight junction barrier dysfunction is associated with microbiota dysbiosis, activated NLRP3 inflammasome and autophagy

inferredcites →https://doi.org/10.18632/oncotarget.16458openalex-snapshot

Gut microbiota drives the attenuation of dextran sulphate sodium-induced colitis by Huangqin decoction

inferredcites →https://doi.org/10.20407/fmj.2020-003openalex-snapshot

A new murine ileostomy model: recycling stool prevents intestinal atrophy in the distal side of ileostomy.

inferredcites →https://doi.org/10.2174/1876142911305020001openalex-snapshot

Formulated Squalene for Food Related Applications

inferredcites →https://doi.org/10.3389/fmicb.2021.777456openalex-snapshot

Effects of Clostridium butyricum on Growth Performance, Gut Microbiota and Intestinal Barrier Function of Broilers

inferredcites →https://doi.org/10.3389/fmicb.2021.784211openalex-snapshot

Caffeic Acid Supplement Alleviates Colonic Inflammation and Oxidative Stress Potentially Through Improved Gut Microbiota Community in Mice

inferredcites →https://doi.org/10.3389/fped.2020.602047openalex-snapshot

Supplemental Insulin-Like Growth Factor-1 and Necrotizing Enterocolitis in Preterm Pigs

inferredcites →https://doi.org/10.3389/fphar.2021.693048openalex-snapshot

Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1

inferredcites →https://doi.org/10.3389/fvets.2021.668003openalex-snapshot

Effects of Adding Eubiotic Lignocellulose on the Growth Performance, Laying Performance, Gut Microbiota, and Short-Chain Fatty Acids of Two Breeds of Hens

inferredcites →https://doi.org/10.3390/ani10020290openalex-snapshot

Chloroquine Downregulation of Intestinal Autophagy to Alleviate Biological Stress in Early-Weaned Piglets

inferredcites →https://doi.org/10.3390/ani10091649openalex-snapshot

Evaluation of Bacillus licheniformis-Fermented Feed Additive as an Antibiotic Substitute: Effect on the Growth Performance, Diarrhea Incidence, and Cecal Microbiota in Weaning Piglets

inferredcites →https://doi.org/10.3390/ani11020266openalex-snapshot

Effects of Commercial Antioxidants in Feed on Growth Performance and Oxidative Stress Status of Weaned Piglets

inferredcites →https://doi.org/10.3390/ani11020402openalex-snapshot

Using Nutritional Strategies to Shape the Gastro-Intestinal Tracts of Suckling and Weaned Piglets

inferredcites →https://doi.org/10.3390/ani11030817openalex-snapshot

Dietary Tryptophan Levels Impact Growth Performance and Intestinal Microbial Ecology in Weaned Piglets via Tryptophan Metabolites and Intestinal Antimicrobial Peptides

inferredcites →https://doi.org/10.3390/ani11092511openalex-snapshot

In-Feed Supplementation of Resin Acid-Enriched Composition Modulates Gut Microbiota, Improves Growth Performance, and Reduces Post-Weaning Diarrhea and Gut Inflammation in Piglets

inferredcites →https://doi.org/10.3390/antibiotics10111280openalex-snapshot

Evaluation of Dietary Curcumin Nanospheres in a Weaned Piglet Model

inferredcites →https://doi.org/10.3390/molecules24071220openalex-snapshot

Curcumin and Resveratrol Regulate Intestinal Bacteria and Alleviate Intestinal Inflammation in Weaned Piglets

inferredcites →https://doi.org/10.3390/nu13041331openalex-snapshot

Effects of Anthocyanin on Intestinal Health: A Systematic Review

inferredcites →https://doi.org/10.4014/jmb.1510.10039openalex-snapshot

Advances in Biochemistry and Microbial Production of Squalene and Its Derivatives

inferredcites →https://doi.org/10.4102/ojvr.v82i1.986openalex-snapshot

Investigation of multidrug-resistant fatal colisepticaemia in weanling pigs

inferredcites →https://doi.org/10.7150/thno.47683openalex-snapshot

Embryonic stem cell-derived mesenchymal stem cells promote colon epithelial integrity and regeneration by elevating circulating IGF-1 in colitis mice

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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A neutral polysaccharide from Persicaria hydropiper (L.) Spach ameliorates lipopolysaccharide-induced intestinal barrier injury via regulating the gut microbiota and modulating AKT/PI3K/mTOR and MAPK signaling pathways

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Abnormal lipid metabolism and inflammatory response induced by aluminum led to the cognitive decline in mice

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inferred← citeshttps://doi.org/10.1186/s12866-024-03539-3openalex-snapshot

Peritoneal dialysis promotes microbial-driven biosynthesis pathways of sesquiterpenes and triterpenes compounds in end-stage renal disease patients

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Changes in the bactericidal activity of pig blood serum when using nanoaquachelates, taking into account vegetative regulation

inferred← citeshttps://doi.org/10.32718/ujvas7-3.04openalex-snapshot

The effect of specific immunoglobulins on sow milk parameters and piglet productivity

inferred← citeshttps://doi.org/10.3389/fphar.2024.1476407openalex-snapshot

GYY4137, as a slow-releasing H2S donor, ameliorates sodium deoxycholate–induced chronic intestinal barrier injury and gut microbiota dysbiosis

inferred← citeshttps://doi.org/10.3389/fvets.2023.1284500openalex-snapshot

The physiological function of squalene and its application prospects in animal husbandry

inferred← citeshttps://doi.org/10.3390/ani13162600openalex-snapshot

Squalene Supplementation as a Novel to Increase PUFA Content in Fish Tissues

inferred← citeshttps://doi.org/10.3390/antiox13101188openalex-snapshot

Early Weaning Inhibits Intestinal Stem Cell Expansion to Disrupt the Intestinal Integrity of Duroc Piglets via Regulating the Keap1/Nrf2 Signaling

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Oryza sativa L. Indica Seed Coat Ameliorated Concanavalin A—Induced Acute Hepatitis in Mice via MDM2/p53 and PKCα/MAPK1 Signaling Pathways

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Red Rice Seed Coat Targeting SPHK2 Ameliorated Alcoholic Liver Disease via Restored Intestinal Barrier and Improved Gut Microbiota in Mice

inferred← citeshttps://doi.org/10.3390/vetsci11080333openalex-snapshot

Chloroquine Downregulation of Intestinal Autophagy Changed Intestinal Microbial Community Compositions and Metabolite Profiles in Piglets

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