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Centrosome Dynamics and Its Role in Inflammatory Response and Metastatic Process
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/1873-3468.13087openalex-snapshot
Rho signaling research: history, current status and future directions
inferredcites →https://doi.org/10.1002/1873-3468.13272openalex-snapshot
Arsenate‐mediated G2 cell cycle arrest in U‐2 OS cells involves phosphorylation of human polycomb protein 2 by p38 MAPK
inferredcites →https://doi.org/10.1002/eji.200939513openalex-snapshot
Targeted inhibition of IL‐10‐secreting CD25 − Treg via p38 MAPK suppression in cancer immunotherapy
inferredcites →https://doi.org/10.1002/ijc.31191openalex-snapshot
Inhibition of MK2 suppresses IL‐1β, IL‐6, and TNF‐α‐dependent colorectal cancer growth
inferredcites →https://doi.org/10.1002/mc.22303openalex-snapshot
Keratinocyte p38δ loss inhibits Ras-induced tumor formation, while systemic p38δ loss enhances skin inflammation in the early phase of chemical carcinogenesis in mouse skin
inferredcites →https://doi.org/10.1007/978-1-4939-7780-2_1openalex-snapshot
The Genomic Characteristics and Origin of Chromothripsis
inferredcites →https://doi.org/10.1007/978-3-030-23173-6_5openalex-snapshot
RhoA Pathway and Actin Regulation of the Golgi/Centriole Complex
inferredcites →https://doi.org/10.1007/978-3-642-28160-0_3openalex-snapshot
Microenvironments Dictating Tumor Cell Dormancy
inferredcites →https://doi.org/10.1007/s00005-016-0453-3openalex-snapshot
Functions of Cancer-Derived Extracellular Vesicles in Immunosuppression
inferredcites →https://doi.org/10.1016/j.bbamcr.2007.03.010openalex-snapshot
p38 MAP-Kinases pathway regulation, function and role in human diseases
inferredcites →https://doi.org/10.1016/j.ccell.2018.04.010openalex-snapshot
Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells
inferredcites →https://doi.org/10.1016/j.ccr.2008.06.016openalex-snapshot
Hepatocyte Necrosis Induced by Oxidative Stress and IL-1α Release Mediate Carcinogen-Induced Compensatory Proliferation and Liver Tumorigenesis
inferredcites →https://doi.org/10.1016/j.ccr.2014.02.019openalex-snapshot
Dual Function of p38α MAPK in Colon Cancer: Suppression of Colitis-Associated Tumor Initiation but Requirement for Cancer Cell Survival
inferredcites →https://doi.org/10.1016/j.cell.2011.02.013openalex-snapshot
Hallmarks of Cancer: The Next Generation
inferredcites →https://doi.org/10.1016/j.cell.2016.11.037openalex-snapshot
Emerging Biological Principles of Metastasis
inferredcites →https://doi.org/10.1016/j.cell.2017.01.018openalex-snapshot
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
inferredcites →https://doi.org/10.1016/j.cell.2018.08.027openalex-snapshot
The Multifaceted Role of Chromosomal Instability in Cancer and Its Microenvironment
inferredcites →https://doi.org/10.1016/j.cellsig.2017.02.018openalex-snapshot
MKP-1 negatively regulates LPS-mediated IL-1β production through p38 activation and HIF-1α expression
inferredcites →https://doi.org/10.1016/j.celrep.2013.10.046openalex-snapshot
An IKKα-Nucleophosmin Axis Utilizes Inflammatory Signaling to Promote Genome Integrity
inferredcites →https://doi.org/10.1016/j.celrep.2018.09.060openalex-snapshot
The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α
inferredcites →https://doi.org/10.1016/j.cels.2016.09.001openalex-snapshot
Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers
inferredcites →https://doi.org/10.1016/j.coi.2014.01.004openalex-snapshot
New insights into cancer immunoediting and its three component phases — elimination, equilibrium and escape
inferredcites →https://doi.org/10.1016/j.coi.2017.11.004openalex-snapshot
Cytosolic sensing of immuno-stimulatory DNA, the enemy within
inferredcites →https://doi.org/10.1016/j.coi.2018.09.017openalex-snapshot
SAMHD1 and the innate immune response to cytosolic DNA during DNA replication
inferredcites →https://doi.org/10.1016/j.cub.2007.10.065openalex-snapshot
Cell-Cycle Progression without an Intact Microtubule Cytoskeleton
inferredcites →https://doi.org/10.1016/j.cub.2010.01.034openalex-snapshot
Mechanisms of Chromosomal Instability
inferredcites →https://doi.org/10.1016/j.devcel.2016.04.023openalex-snapshot
The Centrosome Undergoes Plk1-Independent Interphase Maturation during Inflammation and Mediates Cytokine Release
inferredcites →https://doi.org/10.1016/j.devcel.2019.04.002openalex-snapshot
The Emerging Link between Centrosome Aberrations and Metastasis
inferredcites →https://doi.org/10.1016/j.intimp.2016.12.028openalex-snapshot
Transmembrane tumor necrosis factor-α promotes the recruitment of MDSCs to tumor tissue by upregulating CXCR4 expression via TNFR2
inferredcites →https://doi.org/10.1016/j.molcel.2018.11.010openalex-snapshot
RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation
inferredcites →https://doi.org/10.1016/j.molmed.2020.01.011openalex-snapshot
The Centrosome Linker and Its Role in Cancer and Genetic Disorders
inferredcites →https://doi.org/10.1016/j.semcancer.2015.03.004openalex-snapshot
Immune evasion in cancer: Mechanistic basis and therapeutic strategies
inferredcites →https://doi.org/10.1016/j.semcancer.2018.08.009openalex-snapshot
Cancer cell plasticity: Impact on tumor progression and therapy response
inferredcites →https://doi.org/10.1016/j.tcb.2020.06.006openalex-snapshot
Polyploidy: A Biological Force From Cells to Ecosystems
inferredcites →https://doi.org/10.1016/j.tips.2019.04.005openalex-snapshot
Cancer and Microenvironment Plasticity: Double-Edged Swords in Metastasis
inferredcites →https://doi.org/10.1016/j.urolonc.2003.12.012openalex-snapshot
ERK(MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK)
inferredcites →https://doi.org/10.1016/j.wneu.2018.11.077openalex-snapshot
The Relationship Between Phospho-p38, Matrix Metalloproteinase 9, and Major Histocompatibility Complex Class I Chain-Related Molecule A Expression in Pituitary Adenomas Demonstrates a New Mechanism of Pituitary Adenoma Immune Escape
inferredcites →https://doi.org/10.1016/j.yexcr.2013.05.007openalex-snapshot
LPS converts Gr-1+CD115+ myeloid-derived suppressor cells from M2 to M1 via P38 MAPK
inferredcites →https://doi.org/10.1016/s0968-0004(00)01595-4openalex-snapshot
p38 MAP kinases: beyond the stress response
inferredcites →https://doi.org/10.1038/35075107openalex-snapshot
Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase
inferredcites →https://doi.org/10.1038/35101065openalex-snapshot
Chromosome segregation and cancer: cutting through the mystery
inferredcites →https://doi.org/10.1038/cdd.2009.36openalex-snapshot
p38α blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1α- to FoxO-dependent transcription
inferredcites →https://doi.org/10.1038/ncb1529openalex-snapshot
Loss of centrosome integrity induces p38—p53—p21-dependent G1—S arrest
inferredcites →https://doi.org/10.1038/ncb2861openalex-snapshot
TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling
inferredcites →https://doi.org/10.1038/ncomms10075openalex-snapshot
p38- and MK2-dependent signalling promotes stress-induced centriolar satellite remodelling via 14-3-3-dependent sequestration of CEP131/AZI1
inferredcites →https://doi.org/10.1038/ncomms5229openalex-snapshot
p38 MAPK-inhibited dendritic cells induce superior antitumour immune responses and overcome regulatory T-cell-mediated immunosuppression
inferredcites →https://doi.org/10.1038/nrc2694openalex-snapshot
Signal integration by JNK and p38 MAPK pathways in cancer development
inferredcites →https://doi.org/10.1038/nrc3793openalex-snapshot
Mechanisms of disseminated cancer cell dormancy: an awakening field
inferredcites →https://doi.org/10.1038/nrm.2017.127openalex-snapshot
Once and only once: mechanisms of centriole duplication and their deregulation in disease
inferredcites →https://doi.org/10.1038/onc.2008.262openalex-snapshot
Phosphorylation of Plk1 at Ser326 regulates its functions during mitotic progression
inferredcites →https://doi.org/10.1038/onc.2015.158openalex-snapshot
p38γ MAPK is required for inflammation-associated colon tumorigenesis
inferredcites →https://doi.org/10.1038/s41388-019-0963-7openalex-snapshot
Rho GTPases in cancer: friend or foe?
inferredcites →https://doi.org/10.1038/s41388-019-0995-zopenalex-snapshot
Centrosome loss results in an unstable genome and malignant prostate tumors
inferredcites →https://doi.org/10.1038/s41392-020-0134-xopenalex-snapshot
Molecular principles of metastasis: a hallmark of cancer revisited
inferredcites →https://doi.org/10.1038/s41467-020-15279-9openalex-snapshot
Degree and site of chromosomal instability define its oncogenic potential
inferredcites →https://doi.org/10.1038/s41556-018-0214-0openalex-snapshot
Dormant tumour cells, their niches and the influence of immunity
inferredcites →https://doi.org/10.1038/s41568-018-0084-6openalex-snapshot
Cytokinesis defects and cancer
inferredcites →https://doi.org/10.1038/s41586-020-2690-1openalex-snapshot
Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer
inferredcites →https://doi.org/10.1038/s41588-019-0399-6openalex-snapshot
Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids
inferredcites →https://doi.org/10.1038/s41591-019-0595-zopenalex-snapshot
A clonal expression biomarker associates with lung cancer mortality
inferredcites →https://doi.org/10.1038/sj.bjc.6603067openalex-snapshot
COX-2-mediated stimulation of the lymphangiogenic factor VEGF-C in human breast cancer
inferredcites →https://doi.org/10.1042/bj20100323openalex-snapshot
Mechanisms and functions of p38 MAPK signalling
inferredcites →https://doi.org/10.1073/pnas.1016917108openalex-snapshot
C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells
inferredcites →https://doi.org/10.1073/pnas.1814705115openalex-snapshot
Protein kinase p38α signaling in dendritic cells regulates colon inflammation and tumorigenesis
inferredcites →https://doi.org/10.1074/jbc.c100685200openalex-snapshot
MK2 Targets AU-rich Elements and Regulates Biosynthesis of Tumor Necrosis Factor and Interleukin-6 Independently at Different Post-transcriptional Levels
inferredcites →https://doi.org/10.1074/jbc.m110.136473openalex-snapshot
MAPKAP Kinase 2 Blocks Tristetraprolin-directed mRNA Decay by Inhibiting CAF1 Deadenylase Recruitment
inferredcites →https://doi.org/10.1074/jbc.m700735200openalex-snapshot
A Functional Role for p38 MAPK in Modulating Mitotic Transit in the Absence of Stress
inferredcites →https://doi.org/10.1080/15384101.2018.1559557openalex-snapshot
Mitotic slippage: an old tale with a new twist
inferredcites →https://doi.org/10.1083/jcb.200606051openalex-snapshot
Inhibition of centrosome protein assembly leads to p53-dependent exit from the cell cycle
inferredcites →https://doi.org/10.1083/jcb.200905057openalex-snapshot
Proliferation of aneuploid human cells is limited by a p53-dependent mechanism
inferredcites →https://doi.org/10.1091/mbc.e10-02-0125openalex-snapshot
P38 Mitogen-activated Protein Kinase Activity Is Required during Mitosis for Timely Satisfaction of the Mitotic Checkpoint But Not for the Fidelity of Chromosome Segregation
inferredcites →https://doi.org/10.1098/rsob.180062openalex-snapshot
Who are you, subdistal appendages of centriole?
inferredcites →https://doi.org/10.1101/2020.01.09.898684openalex-snapshot
Centrosome impairment causes DNA replication stress through MLK3/MK2 signaling and R-loop formation
inferredcites →https://doi.org/10.1101/gad.314351.118openalex-snapshot
The impact of mitotic errors on cell proliferation and tumorigenesis
inferredcites →https://doi.org/10.1111/febs.15473openalex-snapshot
Microtubule‐associated proteins and emerging links to primary cilium structure, assembly, maintenance, and disassembly
inferredcites →https://doi.org/10.1111/joim.12470openalex-snapshot
The immune system and cancer evasion strategies: therapeutic concepts
inferredcites →https://doi.org/10.1126/science.280.5363.599openalex-snapshot
Activation of the Protein Kinase p38 in the Spindle Assembly Checkpoint and Mitotic Arrest
inferredcites →https://doi.org/10.1126/scisignal.aao3428openalex-snapshot
The nuclear translocation of the kinases p38 and JNK promotes inflammation-induced cancer
inferredcites →https://doi.org/10.1128/mcb.00717-10openalex-snapshot
Phosphorylation of Tristetraprolin by MK2 Impairs AU-Rich Element mRNA Decay by Preventing Deadenylase Recruitment
inferredcites →https://doi.org/10.1128/mcb.00945-06openalex-snapshot
Novel mRNA Targets for Tristetraprolin (TTP) Identified by Global Analysis of Stabilized Transcripts in TTP-Deficient Fibroblasts
inferredcites →https://doi.org/10.1128/mcb.21.9.6461-6469.2001openalex-snapshot
Mitogen-Activated Protein Kinase p38 Controls the Expression and Posttranslational Modification of Tristetraprolin, a Regulator of Tumor Necrosis Factor Alpha mRNA Stability
inferredcites →https://doi.org/10.1128/mcb.26.6.2399-2407.2006openalex-snapshot
Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Regulates Tumor Necrosis Factor mRNA Stability and Translation Mainly by Altering Tristetraprolin Expression, Stability, and Binding to Adenine/Uridine-Rich Element
inferredcites →https://doi.org/10.1128/mcb.26.6.2408-2418.2006openalex-snapshot
Posttranslational Regulation of Tristetraprolin Subcellular Localization and Protein Stability by p38 Mitogen-Activated Protein Kinase and Extracellular Signal-Regulated Kinase Pathways
inferredcites →https://doi.org/10.1158/0008-5472.can-07-0141openalex-snapshot
EGFR Activation Results in Enhanced Cyclooxygenase-2 Expression through p38 Mitogen-Activated Protein Kinase–Dependent Activation of the Sp1/Sp3 Transcription Factors in Human Gliomas
inferredcites →https://doi.org/10.1158/0008-5472.can-08-3820openalex-snapshot
Computational Identification of a p38SAPK-Regulated Transcription Factor Network Required for Tumor Cell Quiescence
inferredcites →https://doi.org/10.1158/0008-5472.can-14-0870openalex-snapshot
Pro-Oncogenic Role of Alternative p38 Mitogen-Activated Protein Kinases p38γ and p38δ, Linking Inflammation and Cancer in Colitis-Associated Colon Cancer
inferredcites →https://doi.org/10.1158/0008-5472.can-18-3235openalex-snapshot
Chromosomal Instability in Tumor Initiation and Development
inferredcites →https://doi.org/10.1158/1078-0432.ccr-09-0399openalex-snapshot
Activation of p38 Mitogen-Activated Protein Kinase Drives Dendritic Cells to Become Tolerogenic inRetTransgenic Mice Spontaneously Developing Melanoma
inferredcites →https://doi.org/10.1158/2159-8290.cd-19-0761openalex-snapshot
The Cytosolic DNA-Sensing cGAS–STING Pathway in Cancer
inferredcites →https://doi.org/10.1182/blood-2005-06-2486openalex-snapshot
Tumor evasion of the immune system: inhibiting p38 MAPK signaling restores the function of dendritic cells in multiple myeloma
inferredcites →https://doi.org/10.1182/blood-2006-09-047563openalex-snapshot
Activation of MAP kinase p38 is critical for the cell-cycle–controlled suppressor function of regulatory T cells
inferredcites →https://doi.org/10.1182/blood-2006-10-051482openalex-snapshot
Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-γ and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway
inferredcites →https://doi.org/10.1186/s13039-019-0429-1openalex-snapshot
The emerging links between chromosomal instability (CIN), metastasis, inflammation and tumour immunity
inferredcites →https://doi.org/10.1186/s13046-019-1167-2openalex-snapshot
MAPKAPK2 plays a crucial role in the progression of head and neck squamous cell carcinoma by regulating transcript stability
inferredcites →https://doi.org/10.1242/jcs.068254openalex-snapshot
Loss of p38γ MAPK induces pleiotropic mitotic defects and massive cell death
inferredcites →https://doi.org/10.1371/journal.pone.0003302openalex-snapshot
P38 MAP Kinase Signaling Is Required for the Conversion of CD4+CD25− T Cells into iTreg
inferredcites →https://doi.org/10.1371/journal.pone.0011247openalex-snapshot
MAPK-Activated Protein Kinase 2 Is Required for Mouse Meiotic Spindle Assembly and Kinetochore-Microtubule Attachment
inferredcites →https://doi.org/10.1371/journal.pone.0019081openalex-snapshot
ALMS1-Deficient Fibroblasts Over-Express Extra-Cellular Matrix Components, Display Cell Cycle Delay and Are Resistant to Apoptosis
inferredcites →https://doi.org/10.1371/journal.pone.0171738openalex-snapshot
p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging
inferredcites →https://doi.org/10.15252/embj.201899630openalex-snapshot
Actin filaments regulate microtubule growth at the centrosome
inferredcites →https://doi.org/10.15252/emmm.201708403openalex-snapshot
Myeloid p38α signaling promotes intestinal IGF‐1 production and inflammation‐associated tumorigenesis
inferredcites →https://doi.org/10.18632/oncotarget.10003openalex-snapshot
TGF-β1 contributes to CD8+ Treg induction through p38 MAPK signaling in ovarian cancer microenvironment
inferredcites →https://doi.org/10.18632/oncotarget.3816openalex-snapshot
Pharmacological inhibition of p38 MAPK reduces tumor growth in patient-derived xenografts from colon tumors
inferredcites →https://doi.org/10.18632/oncotarget.4320openalex-snapshot
Combined deletion of p38γ and p38δ reduces skin inflammation and protects from carcinogenesis
inferredcites →https://doi.org/10.18632/oncotarget.9260openalex-snapshot
Cisplatin induces tolerogenic dendritic cells in response to TLR agonists via the abundant production of IL-10, thereby promoting Th2- and Tr1-biased T-cell immunity
inferredcites →https://doi.org/10.18632/oncotarget.9911openalex-snapshot
C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms
inferredcites →https://doi.org/10.26508/lsa.201800135openalex-snapshot
Centrosome guides spatial activation of Rac to control cell polarization and directed cell migration
inferredcites →https://doi.org/10.3322/caac.21492openalex-snapshot
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
inferredcites →https://doi.org/10.3390/biology6010012openalex-snapshot
The Consequences of Chromosome Segregation Errors in Mitosis and Meiosis
inferredcites →https://doi.org/10.3390/cells8070701openalex-snapshot
The Centrosome and the Primary Cilium: The Yin and Yang of a Hybrid Organelle
inferredcites →https://doi.org/10.3390/cells9051069openalex-snapshot
Cell Cycle-Dependent Dynamics of the Golgi-Centrosome Association in Motile Cells
inferredcites →https://doi.org/10.3390/cells9061390openalex-snapshot
A Proximity Mapping Journey into the Biology of the Mammalian Centrosome/Cilium Complex
inferredcites →https://doi.org/10.3390/cells9102156openalex-snapshot
Principal Postulates of Centrosomal Biology. Version 2020
inferredcites →https://doi.org/10.3390/genes11060642openalex-snapshot
DNA Replication Stress and Chromosomal Instability: Dangerous Liaisons
inferredcites →https://doi.org/10.3390/ijms21061913openalex-snapshot
The p38 Pathway: From Biology to Cancer Therapy
inferredcites →https://doi.org/10.4049/jimmunol.0803113openalex-snapshot
TLR3 Ligand Induces NF-κB Activation and Various Fates of Multiple Myeloma Cells Depending on IFN-α Production
inferredcites →https://doi.org/10.4161/cc.5.15.3006openalex-snapshot
CDC25B Phosphorylation by p38 and MK-2
inferredcites →https://doi.org/10.4161/onci.20365openalex-snapshot
Tumor-mediated inhibition of human dendritic cell differentiation and function is consistently counteracted by combined p38 MAPK and STAT3 inhibition
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4635430openalex-extracted
Supernumerary Centrosome Promotes Glycogen Levels in Hepatocytes Via Metabolic Reprogramming in DEN/CCL4-Induced Mice
inferred← citeshttps://doi.org/10.1002/advs.202501015openalex-snapshot
Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities
inferred← citeshttps://doi.org/10.1016/j.biopha.2021.112292openalex-snapshot
Centrosomal-associated Proteins: Potential therapeutic targets for solid tumors?
inferred← citeshttps://doi.org/10.1152/ajpcell.00212.2024openalex-snapshot
Perfluorooctane sulfonate-induced Sertoli cell injury through c-Jun N-terminal kinase: a study by RNA-Seq
inferred← citeshttps://doi.org/10.1186/s11658-025-00722-wopenalex-snapshot
Rho-GTPases subfamily: cellular defectors orchestrating viral infection
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3488981/v1openalex-snapshot
A novel centrosome-related gene signature for predicting prognosis and treatment effect of lung adenocarcinoma
inferred← citeshttps://doi.org/10.3103/s0095452725020045openalex-snapshot
Distinct Functions of the PH Domain in BCR/ABL p210 Isoform: Interaction with Cytoskeletal and Membrane Remodeling Proteins
inferred← citeshttps://doi.org/10.3389/fcell.2026.1877870openalex-snapshot
The roles of centrosome amplification in diabetes-associated diseases
inferred← citeshttps://doi.org/10.3390/cancers13215386openalex-snapshot
RHO GTPase-Related Long Noncoding RNAs in Human Cancers
inferred← citeshttps://doi.org/10.3390/ijms241512214openalex-snapshot
Blood Plasma Small Non-Coding RNAs as Diagnostic Molecules for the Progesterone-Receptor-Negative Phenotype of Serous Ovarian Tumors
inferred← citeshttps://doi.org/10.3390/ijms251810094openalex-snapshot
Deep Immune and RNA Profiling Revealed Distinct Circulating CD163+ Monocytes in Diabetes-Related Complications
inferred← citeshttps://doi.org/10.7150/ijbs.75340openalex-snapshot
SIRT7 Downregulation Promotes Breast Cancer Metastasis Via LAP2α-Induced Chromosomal Instability
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