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Chalcone Derivatives: Role in Anticancer Therapy
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/anie.201208749openalex-snapshot
Target Identification for Small Bioactive Molecules: Finding the Needle in the Haystack
inferredcites →https://doi.org/10.1002/ardp.201000391openalex-snapshot
Anti‐Tumor Activity of New Artemisinin–Chalcone Hybrids
inferredcites →https://doi.org/10.1002/ardp.201900350openalex-snapshot
Chalcone hybrids and their antimalarial activity
inferredcites →https://doi.org/10.1002/cbin.11480openalex-snapshot
Proteasomal dysfunction and ER stress triggers 2′‐hydroxy‐retrochalcone‐induced paraptosis in cancer cells
inferredcites →https://doi.org/10.1002/cmdc.201700001openalex-snapshot
Design, Synthesis, and Biological Evaluation of Chalcone‐Containing Shikonin Derivatives as Inhibitors of Tubulin Polymerization
inferredcites →https://doi.org/10.1002/ijc.25868openalex-snapshot
Butein, a tetrahydroxychalcone, suppresses cancer‐induced osteoclastogenesis through inhibition of receptor activator of nuclear factor‐kappaB ligand signaling
inferredcites →https://doi.org/10.1002/jcb.27460openalex-snapshot
Novel TGF‐β1 inhibitor antagonizes TGF‐β1‐induced epithelial‐mesenchymal transition in human A549 lung cancer cells
inferredcites →https://doi.org/10.1002/jcb.28782openalex-snapshot
Cancer drug resistance: A fleet to conquer
inferredcites →https://doi.org/10.1002/mc.22386openalex-snapshot
Anti-cancer activity oftrans-chalcone in osteosarcoma: Involvement of Sp1 and p53
inferredcites →https://doi.org/10.1002/med.21446openalex-snapshot
Artemisinin as an anticancer drug: Recent advances in target profiling and mechanisms of action
inferredcites →https://doi.org/10.1002/med.21643openalex-snapshot
Hybrid molecules with potential in vitro antiplasmodial and in vivo antimalarial activity against drug‐resistant Plasmodium falciparum
inferredcites →https://doi.org/10.1002/med.21698openalex-snapshot
Chalcone hybrids as potential anticancer agents: Current development, mechanism of action, and structure‐activity relationship
inferredcites →https://doi.org/10.1002/mnfr.201500407openalex-snapshot
Molecular structure‐function relationship of dietary polyphenols for inhibiting VEGF‐induced VEGFR‐2 activity
inferredcites →https://doi.org/10.1007/s00044-016-1509-yopenalex-snapshot
Synthesis and in vitro biological activities of ferrocenyl–chalcone amides
inferredcites →https://doi.org/10.1007/s00044-018-2156-2openalex-snapshot
Heterocycles 44. Synthesis, characterization and anticancer activity of new thiazole ortho-hydroxychalcones
inferredcites →https://doi.org/10.1007/s00044-019-02434-1openalex-snapshot
Synthesis, structural characterization, and cytotoxic evaluation of chalcone derivatives
inferredcites →https://doi.org/10.1007/s10495-014-0975-2openalex-snapshot
Anti-tumour activity of a novel coumarin–chalcone hybrid is mediated through intrinsic apoptotic pathway by inducing PUMA and altering Bax/Bcl-2 ratio
inferredcites →https://doi.org/10.1007/s10534-016-9933-5openalex-snapshot
Metal complexes of 3-(4-bromophenyl)-1-pyridin-2-ylprop-2-en-1-one thiosemicarbazone: cytotoxic activity and investigation on the mode of action of the gold(III) complex
inferredcites →https://doi.org/10.1007/s10637-019-00737-zopenalex-snapshot
An orally antitumor chalcone hybrid inhibited HepG2 cells growth and migration as the tubulin binding agent
inferredcites →https://doi.org/10.1007/s11030-016-9688-5openalex-snapshot
Computational predictive models for P-glycoprotein inhibition of in-house chalcone derivatives and drug-bank compounds
inferredcites →https://doi.org/10.1007/s11101-014-9387-8openalex-snapshot
Naturally occurring chalcones and their biological activities
inferredcites →https://doi.org/10.1007/s11655-012-1142-7openalex-snapshot
Isobavachalcone: An overview
inferredcites →https://doi.org/10.1016/j.abb.2016.07.009openalex-snapshot
Human topoisomerase IB is a target of a thiosemicarbazone copper(II) complex
inferredcites →https://doi.org/10.1016/j.bcp.2005.12.032openalex-snapshot
Inhibition of TNFα-induced activation of nuclear factor κB by kava (Piper methysticum) derivatives
inferredcites →https://doi.org/10.1016/j.bcp.2020.113848openalex-snapshot
Biological evaluation of non-basic chalcone CYB-2 as a dual ABCG2/ABCB1 inhibitor
inferredcites →https://doi.org/10.1016/j.bioorg.2016.08.003openalex-snapshot
Anticancer and structure-activity relationship evaluation of 3-(naphthalen-2-yl)-N,5-diphenyl-pyrazoline-1-carbothioamide analogs of chalcone
inferredcites →https://doi.org/10.1016/j.bioorg.2017.03.005openalex-snapshot
Design, synthesis, docking studies and biological evaluation of novel chalcone derivatives as potential histone deacetylase inhibitors
inferredcites →https://doi.org/10.1016/j.bioorg.2017.09.005openalex-snapshot
New indole-based chalconoids as tubulin-targeting antiproliferative agents
inferredcites →https://doi.org/10.1016/j.bioorg.2018.11.032openalex-snapshot
1,3,4-oxadiazole/chalcone hybrids: Design, synthesis, and inhibition of leukemia cell growth and EGFR, Src, IL-6 and STAT3 activities
inferredcites →https://doi.org/10.1016/j.bioorg.2019.01.023openalex-snapshot
Discovery of novel chalcone-dithiocarbamates as ROS-mediated apoptosis inducers by inhibiting catalase
inferredcites →https://doi.org/10.1016/j.bioorg.2019.102997openalex-snapshot
EGFR inhibitors and apoptotic inducers: Design, synthesis, anticancer activity and docking studies of novel xanthine derivatives carrying chalcone moiety as hybrid molecules
inferredcites →https://doi.org/10.1016/j.bioorg.2019.103021openalex-snapshot
Medicinal chemistry of indole derivatives: Current to future therapeutic prospectives
inferredcites →https://doi.org/10.1016/j.bioorg.2019.103530openalex-snapshot
Design, synthesis and bioactivity evaluation of coumarin-chalcone hybrids as potential anticancer agents
inferredcites →https://doi.org/10.1016/j.bioorg.2020.103780openalex-snapshot
Some 1,3,5-trisubstituted pyrazoline derivatives targeting breast cancer: Design, synthesis, cytotoxic activity, EGFR inhibition and molecular docking
inferredcites →https://doi.org/10.1016/j.bioorg.2020.104447openalex-snapshot
Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors
inferredcites →https://doi.org/10.1016/j.bmc.2009.09.039openalex-snapshot
Combretastatin-like chalcones as inhibitors of microtubule polymerization. Part 1: Synthesis and biological evaluation of antivascular activity
inferredcites →https://doi.org/10.1016/j.bmc.2009.09.044openalex-snapshot
Combretastatin-like chalcones as inhibitors of microtubule polymerisation. Part 2: Structure-based discovery of alpha-aryl chalcones
inferredcites →https://doi.org/10.1016/j.bmc.2009.11.003openalex-snapshot
A boronic acid chalcone analog of combretastatin A-4 as a potent anti-proliferation agent
inferredcites →https://doi.org/10.1016/j.bmc.2012.02.050openalex-snapshot
Synthesis and biological evaluation of bifendate–chalcone hybrids as a new class of potential P-glycoprotein inhibitors
inferredcites →https://doi.org/10.1016/j.bmc.2013.04.086openalex-snapshot
Chromenylchalcones showing cytotoxicity on human colon cancer cell lines and in silico docking with aurora kinases
inferredcites →https://doi.org/10.1016/j.bmc.2014.02.005openalex-snapshot
Synthesis, biological evaluation and 3D-QSAR studies of new chalcone derivatives as inhibitors of human P-glycoprotein
inferredcites →https://doi.org/10.1016/j.bmc.2014.02.028openalex-snapshot
Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents
inferredcites →https://doi.org/10.1016/j.bmc.2014.04.045openalex-snapshot
Anti-proliferative effect of chalcone derivatives through inactivation of NF-κB in human cancer cells
inferredcites →https://doi.org/10.1016/j.bmc.2016.09.051openalex-snapshot
Synthesis and topoisomerases inhibitory activity of heteroaromatic chalcones
inferredcites →https://doi.org/10.1016/j.bmc.2016.12.019openalex-snapshot
Design and synthesis of new coumarin hybrids and insight into their mode of antiproliferative action
inferredcites →https://doi.org/10.1016/j.bmc.2017.09.019openalex-snapshot
Synthesis and biological evaluation of novel synthetic chalcone derivatives as anti-tumor agents targeting Cat L and Cat K
inferredcites →https://doi.org/10.1016/j.bmc.2018.10.045openalex-snapshot
Design, synthesis and QSAR study of 2′-hydroxy-4′-alkoxy chalcone derivatives that exert cytotoxic activity by the mitochondrial apoptotic pathway
inferredcites →https://doi.org/10.1016/j.bmcl.2010.07.128openalex-snapshot
Fluorinated 2′-hydroxychalcones as garcinol analogs with enhanced antioxidant and anticancer activities
inferredcites →https://doi.org/10.1016/j.bmcl.2010.10.116openalex-snapshot
Synthesis and in vitro evaluation of novel coumarin–chalcone hybrids as potential anticancer agents
inferredcites →https://doi.org/10.1016/j.bmcl.2013.11.034openalex-snapshot
Discovery of hybrid Hsp90 inhibitors and their anti-neoplastic effects against gefitinib-resistant non-small cell lung cancer (NSCLC)
inferredcites →https://doi.org/10.1016/j.bmcl.2016.07.012openalex-snapshot
Design, synthesis and antiproliferative activity studies of novel dithiocarbamate–chalcone derivates
inferredcites →https://doi.org/10.1016/j.bmcl.2016.10.029openalex-snapshot
Design, synthesis and activity of novel sorafenib analogues bearing chalcone unit
inferredcites →https://doi.org/10.1016/j.bmcl.2018.06.048openalex-snapshot
Highly selective anthraquinone-chalcone hybrids as potential antileukemia agents
inferredcites →https://doi.org/10.1016/j.canlet.2009.07.002openalex-snapshot
Butein induces G2/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation
inferredcites →https://doi.org/10.1016/j.canlet.2017.05.030openalex-snapshot
Inhibition of CYP4A by a novel flavonoid FLA-16 prolongs survival and normalizes tumor vasculature in glioma
inferredcites →https://doi.org/10.1016/j.ejmech.2014.08.033openalex-snapshot
Recent developments in biological activities of chalcones: A mini review
inferredcites →https://doi.org/10.1016/j.ejmech.2014.10.036openalex-snapshot
Novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitor: Synthesis, anti-invasive and anti-angiogenic properties
inferredcites →https://doi.org/10.1016/j.ejmech.2014.10.055openalex-snapshot
Anthraquinone–chalcone hybrids: Synthesis, preliminary antiproliferative evaluation and DNA-interaction studies
inferredcites →https://doi.org/10.1016/j.ejmech.2014.11.016openalex-snapshot
Synthesis and in vitro biological evaluation of dihydroartemisinyl-chalcone esters
inferredcites →https://doi.org/10.1016/j.ejmech.2015.04.054openalex-snapshot
Discovery of 3-phenylquinolinylchalcone derivatives as potent and selective anticancer agents against breast cancers
inferredcites →https://doi.org/10.1016/j.ejmech.2015.05.004openalex-snapshot
Anti-cancer chalcones: Structural and molecular target perspectives
inferredcites →https://doi.org/10.1016/j.ejmech.2016.03.002openalex-snapshot
Applying the designed multiple ligands approach to inhibit dihydrofolate reductase and thioredoxin reductase for anti-proliferative activity
inferredcites →https://doi.org/10.1016/j.ejmech.2016.03.067openalex-snapshot
The combination of quinazoline and chalcone moieties leads to novel potent heterodimeric modulators of breast cancer resistance protein (BCRP/ABCG2)
inferredcites →https://doi.org/10.1016/j.ejmech.2016.06.035openalex-snapshot
Synthesis of a series of novel dihydroartemisinin monomers and dimers containing chalcone as a linker and their anticancer activity
inferredcites →https://doi.org/10.1016/j.ejmech.2016.08.039openalex-snapshot
Hybrid molecules: The privileged scaffolds for various pharmaceuticals
inferredcites →https://doi.org/10.1016/j.ejmech.2017.02.002openalex-snapshot
Synthesis and biological evaluation of novel pyrazolic chalcone derivatives as novel hepatocellular carcinoma therapeutics
inferredcites →https://doi.org/10.1016/j.ejmech.2017.02.064openalex-snapshot
Ferrocene-embedded flavonoids targeting the Achilles heel of multidrug-resistant cancer cells through collateral sensitivity
inferredcites →https://doi.org/10.1016/j.ejmech.2018.01.010openalex-snapshot
Synthesis of carbazole derivatives containing chalcone analogs as non-intercalative topoisomerase II catalytic inhibitors and apoptosis inducers
inferredcites →https://doi.org/10.1016/j.ejmech.2018.02.065openalex-snapshot
Indole in the target-based design of anticancer agents: A versatile scaffold with diverse mechanisms
inferredcites →https://doi.org/10.1016/j.ejmech.2018.03.047openalex-snapshot
A comprehensive review of chalcone derivatives as antileishmanial agents
inferredcites →https://doi.org/10.1016/j.ejmech.2018.03.073openalex-snapshot
New 1,2,4-triazole-Chalcone hybrids induce Caspase-3 dependent apoptosis in A549 human lung adenocarcinoma cells
inferredcites →https://doi.org/10.1016/j.ejmech.2018.11.034openalex-snapshot
Synthesis and evaluation of chalcone analogues containing a 4-oxoquinazolin-2-yl group as potential anti-tumor agents
inferredcites →https://doi.org/10.1016/j.ejmech.2018.12.019openalex-snapshot
Novel chalcone and flavone derivatives as selective and dual inhibitors of the transport proteins ABCB1 and ABCG2
inferredcites →https://doi.org/10.1016/j.ejmech.2019.04.008openalex-snapshot
Design, synthesis and biological evaluation of pyridine-chalcone derivatives as novel microtubule-destabilizing agents
inferredcites →https://doi.org/10.1016/j.ejmech.2019.04.032openalex-snapshot
Perspectives of medicinally privileged chalcone based metal coordination compounds for biomedical applications
inferredcites →https://doi.org/10.1016/j.ejmech.2019.05.053openalex-snapshot
Design, synthesis and biological evaluation of chalcones as reversers of P-glycoprotein-mediated multidrug resistance
inferredcites →https://doi.org/10.1016/j.ejmech.2019.111587openalex-snapshot
Coumarin-containing hybrids and their anticancer activities
inferredcites →https://doi.org/10.1016/j.ejmech.2019.111691openalex-snapshot
Indole: A privileged scaffold for the design of anti-cancer agents
inferredcites →https://doi.org/10.1016/j.ejmech.2019.111954openalex-snapshot
Design, synthesis, and validation of novel nitrogen-based chalcone analogs against triple negative breast cancer
inferredcites →https://doi.org/10.1016/j.ejphar.2008.01.032openalex-snapshot
Isoliquiritigenin isolated from the roots of Glycyrrhiza uralensis inhibits LPS-induced iNOS and COX-2 expression via the attenuation of NF-κB in RAW 264.7 macrophages
inferredcites →https://doi.org/10.1016/j.ejphar.2017.12.053openalex-snapshot
Antineoplastic activity of isoliquiritigenin, a chalcone compound, in androgen-independent human prostate cancer cells linked to G2/M cell cycle arrest and cell apoptosis
inferredcites →https://doi.org/10.1016/j.ejphar.2019.04.033openalex-snapshot
Isoliquiritigenin suppresses the proliferation and induced apoptosis via miR-32/LATS2/Wnt in nasopharyngeal carcinoma
inferredcites →https://doi.org/10.1016/j.ejps.2008.06.001openalex-snapshot
Modulation of breast cancer resistance protein (BCRP/ABCG2) by non-basic chalcone analogues
inferredcites →https://doi.org/10.1016/j.ejps.2017.06.018openalex-snapshot
A novel chalcone derivative, LQFM064, induces breast cancer cells death via p53, p21, KIT and PDGFRA
inferredcites →https://doi.org/10.1016/j.fct.2013.12.030openalex-snapshot
Licochalcone B inhibits growth of bladder cancer cells by arresting cell cycle progression and inducing apoptosis
inferredcites →https://doi.org/10.1016/j.fct.2015.11.016openalex-snapshot
A novel quinazolinone chalcone derivative induces mitochondrial dependent apoptosis and inhibits PI3K/Akt/mTOR signaling pathway in human colon cancer HCT-116 cells
inferredcites →https://doi.org/10.1016/j.fct.2017.12.028openalex-snapshot
Molecular chemotherapeutic potential of butein: A concise review
inferredcites →https://doi.org/10.1016/j.fct.2018.04.003openalex-snapshot
Novel dual-targeting anti-proliferative dihydrotriazine-chalcone derivatives display suppression of cancer cell invasion and inflammation by inhibiting the NF-κB signaling pathway
inferredcites →https://doi.org/10.1016/j.fct.2020.111663openalex-snapshot
The integrated use of in silico methods for the hepatotoxicity potential of Piper methysticum
inferredcites →https://doi.org/10.1016/j.intimp.2010.12.006openalex-snapshot
The role of chalcones in suppression of NF-κB-mediated inflammation and cancer
inferredcites →https://doi.org/10.1016/j.lfs.2020.118598openalex-snapshot
The dietary flavonoid isoliquiritigenin induced apoptosis and suppressed metastasis in melanoma cells: An in vitro and in vivo study
inferredcites →https://doi.org/10.1016/j.molstruc.2016.01.070openalex-snapshot
Synthesis, characterization and biological activities of some Ru(II) complexes with substituted chalcones and their applications as chemotherapeutics against breast cancer
inferredcites →https://doi.org/10.1016/j.phymed.2015.08.015openalex-snapshot
Potential of butein, a tetrahydroxychalcone to obliterate cancer
inferredcites →https://doi.org/10.1016/j.phymed.2020.153373openalex-snapshot
Trans-chalcone induces death by autophagy mediated by p53 up-regulation and β-catenin down-regulation on human hepatocellular carcinoma HuH7.5 cell line
inferredcites →https://doi.org/10.1016/j.taap.2016.08.023openalex-snapshot
A new brominated chalcone derivative suppresses the growth of gastric cancer cells in vitro and in vivo involving ROS mediated up-regulation of DR5 and 4 expression and apoptosis
inferredcites →https://doi.org/10.1016/j.tiv.2010.08.002openalex-snapshot
Butein suppresses the expression of nuclear factor-kappa B-mediated matrix metalloproteinase-9 and vascular endothelial growth factor in prostate cancer cells
inferredcites →https://doi.org/10.1016/j.tox.2009.11.008openalex-snapshot
Curcumin, resveratrol and flavonoids as anti-inflammatory, cyto- and DNA-protective dietary compounds
inferredcites →https://doi.org/10.1016/s0021-9258(19)30078-xopenalex-snapshot
Interaction of tubulin and cellular microtubules with the new antitumor drug MDL 27048
inferredcites →https://doi.org/10.1016/s0024-3205(00)00974-7openalex-snapshot
Chalcones are potent inhibitors of aromatase and 17β-hydroxysteroid dehydrogenase activities
inferredcites →https://doi.org/10.1016/s0031-9422(00)00187-4openalex-snapshot
A geranylated chalcone with 5α-reductase inhibitory properties from Artocarpus incisus
inferredcites →https://doi.org/10.1016/s0968-0896(99)00218-7openalex-snapshot
Synthesis and biological activity of 4-alkoxy chalcones: potential hydrophobic modulators of p-glycoprotein-mediated multidrug resistance
inferredcites →https://doi.org/10.1016/s1359-6446(03)02713-2openalex-snapshot
Drugs from the deep: marine natural products as drug candidates
inferredcites →https://doi.org/10.1021/acs.chemrev.7b00020openalex-snapshot
Chalcone: A Privileged Structure in Medicinal Chemistry
inferredcites →https://doi.org/10.1021/acs.jmedchem.5b01380openalex-snapshot
Artemisinin-Derived Dimers: Potent Antimalarial and Anticancer Agents
inferredcites →https://doi.org/10.1021/acs.jmedchem.6b00021openalex-snapshot
Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo
inferredcites →https://doi.org/10.1021/acs.jmedchem.6b01253openalex-snapshot
Design, Synthesis, and Biological Evaluation of Coupled Bioactive Scaffolds as Potential Anticancer Agents for Dual Targeting of Dihydrofolate Reductase and Thioredoxin Reductase
inferredcites →https://doi.org/10.1021/acs.jmedchem.8b01755openalex-snapshot
Discovery of Novel Quinoline–Chalcone Derivatives as Potent Antitumor Agents with Microtubule Polymerization Inhibitory Activity
inferredcites →https://doi.org/10.1021/acs.jnatprod.9b01022openalex-snapshot
Licochalcone A Selectively Resensitizes ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Drugs
inferredcites →https://doi.org/10.1021/acs.molpharmaceut.8b00359openalex-snapshot
An Indole–Chalcone Inhibits Multidrug-Resistant Cancer Cell Growth by Targeting Microtubules
inferredcites →https://doi.org/10.1021/acsmedchemlett.8b00289openalex-snapshot
Tariquidar-Related Chalcones and Ketones as ABCG2 Modulators
inferredcites →https://doi.org/10.1021/ar7000843openalex-snapshot
Hybrid Molecules with a Dual Mode of Action: Dream or Reality?
inferredcites →https://doi.org/10.1021/jf205053ropenalex-snapshot
The Chalcone Flavokawain B Induces G 2 /M Cell-Cycle Arrest and Apoptosis in Human Oral Carcinoma HSC-3 Cells through the Intracellular ROS Generation and Downregulation of the Akt/p38 MAPK Signaling Pathway
inferredcites →https://doi.org/10.1021/jm2016073openalex-snapshot
A Synthetic Chalcone as a Potent Inducer of Glutathione Biosynthesis
inferredcites →https://doi.org/10.1021/jm401879zopenalex-snapshot
Symmetric Bis-chalcones as a New Type of Breast Cancer Resistance Protein Inhibitors with a Mechanism Different from That of Chromones
inferredcites →https://doi.org/10.1021/jm801001dopenalex-snapshot
Pt(II) Complexes of a Combretastatin A-4 Analogous Chalcone: Effects of Conjugation on Cytotoxicity, Tumor Specificity, and Long-Term Tumor Growth Suppression
inferredcites →https://doi.org/10.1021/jm9810194openalex-snapshot
Halogenated Chalcones with High-Affinity Binding to P-Glycoprotein: Potential Modulators of Multidrug Resistance
inferredcites →https://doi.org/10.1021/np058080dopenalex-snapshot
Chalcones and Other Compounds from the Exudates of Angelica keiskei and Their Cancer Chemopreventive Effects
inferredcites →https://doi.org/10.1021/tx5003194openalex-snapshot
Flavokawains A and B in Kava, Not Dihydromethysticin, Potentiate Acetaminophen-Induced Hepatotoxicity in C57BL/6 Mice
inferredcites →https://doi.org/10.1038/cdd.2017.187openalex-snapshot
Relevance of the p53–MDM2 axis to aging
inferredcites →https://doi.org/10.1038/nrc3204openalex-snapshot
The diverse and complex roles of NF-κB subunits in cancer
inferredcites →https://doi.org/10.1038/s41419-019-1543-zopenalex-snapshot
Nrf2 signaling and autophagy are complementary in protecting lipopolysaccharide/d-galactosamine-induced acute liver injury by licochalcone A
inferredcites →https://doi.org/10.1038/s41429-020-0280-yopenalex-snapshot
Ferrocenyl chalcone derivatives as possible antimicrobial agents
inferredcites →https://doi.org/10.1038/s41568-018-0005-8openalex-snapshot
Revisiting the role of ABC transporters in multidrug-resistant cancer
inferredcites →https://doi.org/10.1038/s41586-019-1730-1openalex-snapshot
A view on drug resistance in cancer
inferredcites →https://doi.org/10.1038/s41598-017-08422-yopenalex-snapshot
Isoliquiritigenin modulates miR-374a/PTEN/Akt axis to suppress breast cancer tumorigenesis and metastasis
inferredcites →https://doi.org/10.1038/s41598-017-10972-0openalex-snapshot
Novel quinolone chalcones targeting colchicine-binding pocket kill multidrug-resistant cancer cells by inhibiting tubulin activity and MRP1 function
inferredcites →https://doi.org/10.1038/srep45287openalex-snapshot
Coumarin-chalcone hybrid instigates DNA damage by minor groove binding and stabilizes p53 through post translational modifications
inferredcites →https://doi.org/10.1039/c4ob02606copenalex-snapshot
Synthesis of phenstatin/isocombretastatin–chalcone conjugates as potent tubulin polymerization inhibitors and mitochondrial apoptotic inducers
inferredcites →https://doi.org/10.1039/c5ob00197hopenalex-snapshot
Novel carbapenem chalcone derivatives: synthesis, cytotoxicity and molecular docking studies
inferredcites →https://doi.org/10.1039/c7md00193bopenalex-snapshot
Synthesis and biological evaluation of chalcone-linked pyrazolo[1,5-a]pyrimidines as potential anticancer agents
inferredcites →https://doi.org/10.1039/c7nj04271jopenalex-snapshot
Synthesis of novel 1,2,3-triazole based artemisinin derivatives and their antiproliferative activity
inferredcites →https://doi.org/10.1039/d0fo02140gopenalex-snapshot
Discovery of hCES2A inhibitors from Glycyrrhiza inflata via combination of docking-based virtual screening and fluorescence-based inhibition assays
inferredcites →https://doi.org/10.1074/jbc.m700890200openalex-snapshot
Butein, a Tetrahydroxychalcone, Inhibits Nuclear Factor (NF)-κB and NF-κB-regulated Gene Expression through Direct Inhibition of IκBα Kinase β on Cysteine 179 Residue
inferredcites →https://doi.org/10.1080/14756366.2016.1221825openalex-snapshot
Synthesis and bioactivities of halogen bearing phenolic chalcones and their corresponding bis Mannich bases
inferredcites →https://doi.org/10.1080/14756366.2019.1615485openalex-snapshot
Antiproliferative activity and p53 upregulation effects of chalcones on human breast cancer cells
inferredcites →https://doi.org/10.1080/15384101.2019.1673620openalex-snapshot
Cardamonin attenuates chronic inflammation and tumorigenesis in colon
inferredcites →https://doi.org/10.1080/15548627.2018.1501133openalex-snapshot
Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy
inferredcites →https://doi.org/10.1093/carcin/bgu187openalex-snapshot
Dietary compound isoliquiritigenin targets GRP78 to chemosensitize breast cancer stem cells via β-catenin/ABCG2 signaling
inferredcites →https://doi.org/10.1111/bph.13569openalex-snapshot
Butein provides neuroprotective and anti‐neuroinflammatory effects through Nrf2/ARE‐dependent haem oxygenase 1 expression by activating the PI3K/Akt pathway
inferredcites →https://doi.org/10.1111/cas.13441openalex-snapshot
Xanthohumol inhibits angiogenesis by suppressing nuclear factor‐κB activation in pancreatic cancer
inferredcites →https://doi.org/10.1111/cbdd.12738openalex-snapshot
Synthesis and Biological Evaluation of 1,2,3‐triazole tethered Pyrazoline and Chalcone Derivatives
inferredcites →https://doi.org/10.1111/cpr.12226openalex-snapshot
SL4, a chalcone‐based compound, induces apoptosis in human cancer cells by activation of the ROS/MAPK signalling pathway
inferredcites →https://doi.org/10.1111/j.1476-5381.2011.01608.xopenalex-snapshot
Inhibitory kappa B kinases as targets for pharmacological regulation
inferredcites →https://doi.org/10.1111/j.1600-065x.2012.01095.xopenalex-snapshot
Regulation of cell death and autophagy by IKK and NF‐κB: critical mechanisms in immune function and cancer
inferredcites →https://doi.org/10.1111/jcmm.13719openalex-snapshot
Isobavachalcone sensitizes cells to E2‐induced paclitaxel resistance by down‐regulating CD 44 expression in ER + breast cancer cells
inferredcites →https://doi.org/10.1124/jpet.109.165209openalex-snapshot
Butrin, Isobutrin, and Butein from Medicinal Plant Butea monosperma Selectively Inhibit Nuclear Factor-κB in Activated Human Mast Cells: Suppression of Tumor Necrosis Factor-α, Interleukin (IL)-6, and IL-8
inferredcites →https://doi.org/10.1146/annurev-pathol-012414-040349openalex-snapshot
The Roles of MDM2 and MDMX in Cancer
inferredcites →https://doi.org/10.1155/2013/815621openalex-snapshot
An Update on Antitumor Activity of Naturally Occurring Chalcones
inferredcites →https://doi.org/10.1155/2018/1915828openalex-snapshot
Isobavachalcone Induces ROS‐Mediated Apoptosis via Targeting Thioredoxin Reductase 1 in Human Prostate Cancer PC‐3 Cells
inferredcites →https://doi.org/10.1155/2019/2075614openalex-snapshot
Medicinal Plants in the Prevention and Treatment of Colon Cancer
inferredcites →https://doi.org/10.1158/1541-7786.mcr-15-0234openalex-snapshot
Maximizing the Therapeutic Potential of HSP90 Inhibitors
inferredcites →https://doi.org/10.1158/1940-6207.capr-13-0012openalex-snapshot
Licochalcone E Present in Licorice Suppresses Lung Metastasis in the 4T1 Mammary Orthotopic Cancer Model
inferredcites →https://doi.org/10.1177/1177932218821371openalex-snapshot
Potential Anti-Cancer Flavonoids Isolated From Caesalpinia bonduc Young Twigs and Leaves: Molecular Docking and In Silico Studies
inferredcites →https://doi.org/10.1182/blood-2008-04-151944openalex-snapshot
Modification of the cysteine residues in IκBα kinase and NF-κB (p65) by xanthohumol leads to suppression of NF-κB–regulated gene products and potentiation of apoptosis in leukemia cells
inferredcites →https://doi.org/10.1186/1471-2407-9-242openalex-snapshot
A novel chalcone derivative which acts as a microtubule depolymerising agent and an inhibitor of P-gp and BCRP in in-vitro and in-vivoglioblastoma models
inferredcites →https://doi.org/10.1186/1476-4598-12-86openalex-snapshot
The complexity of NF-κB signaling in inflammation and cancer
inferredcites →https://doi.org/10.1186/s12885-015-1901-xopenalex-snapshot
Chemopreventive effect of chalcone derivative, L2H17, in colon cancer development
inferredcites →https://doi.org/10.1186/s12964-019-0338-2openalex-snapshot
Flavokawain B targets protein neddylation for enhancing the anti-prostate cancer effect of Bortezomib via Skp2 degradation
inferredcites →https://doi.org/10.1186/s12974-017-0895-5openalex-snapshot
Isoliquiritigenin alleviates early brain injury after experimental intracerebral hemorrhage via suppressing ROS- and/or NF-κB-mediated NLRP3 inflammasome activation by promoting Nrf2 antioxidant pathway
inferredcites →https://doi.org/10.1186/s13046-019-1351-4openalex-snapshot
Cardamonin inhibits breast cancer growth by repressing HIF-1α-dependent metabolic reprogramming
inferredcites →https://doi.org/10.1186/s13046-019-1361-2openalex-snapshot
Inhibition of COX-2, mPGES-1 and CYP4A by isoliquiritigenin blocks the angiogenic Akt signaling in glioma through ceRNA effect of miR-194-5p and lncRNA NEAT1
inferredcites →https://doi.org/10.1248/bpb.30.1878openalex-snapshot
Isobavachalcone, a Chalcone Constituent of Angelica keiskei, Induces Apoptosis in Neuroblastoma
inferredcites →https://doi.org/10.1248/cpb.59.984openalex-snapshot
Design, Synthesis and Antitumor Activity of Novel Artemisinin Derivatives Using Hybrid Approach
inferredcites →https://doi.org/10.1371/journal.pone.0068566openalex-snapshot
Dietary Compound Isoliquiritigenin Inhibits Breast Cancer Neoangiogenesis via VEGF/VEGFR-2 Signaling Pathway
inferredcites →https://doi.org/10.1371/journal.pone.0202263openalex-snapshot
Trans-chalcone increases p53 activity via DNAJB1/HSP40 induction and CRM1 inhibition
inferredcites →https://doi.org/10.14348/molcells.2019.0129openalex-snapshot
KMS99220 Exerts Anti-Inflammatory Effects, Activates the Nrf2 Signaling and Interferes with IKK, JNK and p38 MAPK via HO-1.
inferredcites →https://doi.org/10.1515/hsz-2016-0148openalex-snapshot
Inhibition of interleukin-3- and interferon- α-induced JAK/STAT signaling by the synthetic α-X-2′,3,4,4′-tetramethoxychalcones α-Br-TMC and α-CF3-TMC
inferredcites →https://doi.org/10.18632/aging.102288openalex-snapshot
A novel chalcone derivative exerts anti-inflammatory and anti-oxidant effects after acute lung injury
inferredcites →https://doi.org/10.18632/aging.104184openalex-snapshot
Cardamonin induces G2/M phase arrest and apoptosis through inhibition of NF-κB and mTOR pathways in ovarian cancer
inferredcites →https://doi.org/10.18632/oncotarget.9527openalex-snapshot
Antivascular and antitumor properties of the tubulin-binding chalcone TUB091
inferredcites →https://doi.org/10.2147/dddt.s192681openalex-snapshot
Isobavachalcone isolated from Psoralea corylifolia inhibits cell proliferation and induces apoptosis via inhibiting the AKT/GSK-3β/β-catenin pathway in colorectal cancer cells
inferredcites →https://doi.org/10.2147/dddt.s243420openalex-snapshot
Isoliquiritigenin Attenuates UUO-Induced Renal Inflammation and Fibrosis by Inhibiting Mincle/Syk/NF-Kappa B Signaling Pathway
inferredcites →https://doi.org/10.2147/dddt.s256756openalex-snapshot
Novel HDAC/Tubulin Dual Inhibitor: Design, Synthesis and Docking Studies of α-Phthalimido-Chalcone Hybrids as Potential Anticancer Agents with Apoptosis-Inducing Activity
inferredcites →https://doi.org/10.2147/ijn.s259432openalex-snapshot
Synergistic Combination of Sodium Aescinate-Stabilized, Polymer-Free, Twin-Like Nanoparticles to Reverse Paclitaxel Resistance
inferredcites →https://doi.org/10.2174/092986712803414132openalex-snapshot
Exploring Pharmacological Significance of Chalcone Scaffold: A Review
inferredcites →https://doi.org/10.2174/0929867325666181001112226openalex-snapshot
A Systematic Review on Anti-diabetic Properties of Chalcones
inferredcites →https://doi.org/10.2174/138955712804586648openalex-snapshot
Synthesis and Biological Evaluation of Chalcone Derivatives (Mini Review)
inferredcites →https://doi.org/10.2174/1568009614666140122160515openalex-snapshot
Molecular Targeted Approaches to Cancer Therapy and Prevention Using Chalcones
inferredcites →https://doi.org/10.2174/1568026616666160824121935openalex-snapshot
New Adamantyl Chalcones: Synthesis, Antimicrobial and Anticancer Activities
inferredcites →https://doi.org/10.2174/1568026617666170914160446openalex-snapshot
Chalcone Derivatives: Anti-inflammatory Potential and Molecular Targets Perspectives
inferredcites →https://doi.org/10.2174/1570161115666170713094319openalex-snapshot
Potential Role of Natural Compounds as Anti-Angiogenic Agents in Cancer
inferredcites →https://doi.org/10.2174/157018011794839475openalex-snapshot
Synthesis of Some Coumarinyl Chalcones and their Antiproliferative Activity Against Breast Cancer Cell Lines
inferredcites →https://doi.org/10.2174/1573406413666171020121244openalex-snapshot
Design, Synthesis, and Evaluation of (2-(Pyridinyl)methylene)-1-tetralone Chalcones for Anticancer and Antimicrobial Activity
inferredcites →https://doi.org/10.2174/1573406415666191206095032openalex-snapshot
Anti-Cholinesterase Activity of Chalcone Derivatives: Synthesis, In Vitro Assay and Molecular Docking Study
inferredcites →https://doi.org/10.2174/1573406416666200817164308openalex-snapshot
Naphthoquinone-based Hydrazone Hybrids: Synthesis and Potent Activity Against Cancer Cell Lines
inferredcites →https://doi.org/10.2174/157488410790410579openalex-snapshot
Trends in Utilization of the Pharmacological Potential of Chalcones
inferredcites →https://doi.org/10.2174/1574892809666140819153902openalex-snapshot
Advances in Chalcones with Anticancer Activities
inferredcites →https://doi.org/10.2174/1871520615666150518093144openalex-snapshot
A Review on Mechanisms of Anti Tumor Activity of Chalcones
inferredcites →https://doi.org/10.2174/1871520616666161221112042openalex-snapshot
Role of Azoles in Cancer Prevention and Treatment: Present and Future Perspectives
inferredcites →https://doi.org/10.2174/1871520617666171003145533openalex-snapshot
New Ferrocene Compounds as Selective Cyclooxygenase (COX-2) Inhibitors: Design, Synthesis, Cytotoxicity and Enzyme-inhibitory Activity
inferredcites →https://doi.org/10.3389/fphar.2019.01390openalex-snapshot
2′-Hydroxychalcone Induced Cytotoxicity via Oxidative Stress in the Lipid-Loaded Hepg2 Cells
inferredcites →https://doi.org/10.3389/fphar.2020.592654openalex-snapshot
Pharmacological Properties of Chalcones: A Review of Preclinical Including Molecular Mechanisms and Clinical Evidence
inferredcites →https://doi.org/10.3390/antiox9030228openalex-snapshot
Dietary Compound Isoliquiritigenin, an Antioxidant from Licorice, Suppresses Triple-Negative Breast Tumor Growth via Apoptotic Death Program Activation in Cell and Xenograft Animal Models
inferredcites →https://doi.org/10.3390/biology9050110openalex-snapshot
In Silico Identification of Type III PKS Chalcone and Stilbene Synthase Homologs in Marine Photosynthetic Organisms
inferredcites →https://doi.org/10.3390/cancers11121968openalex-snapshot
The Chalcone Lonchocarpin Inhibits Wnt/β-Catenin Signaling and Suppresses Colorectal Cancer Proliferation
inferredcites →https://doi.org/10.3390/cancers13010115openalex-snapshot
Perspectives on the Role of Isoliquiritigenin in Cancer
inferredcites →https://doi.org/10.3390/ijms18102025openalex-snapshot
Isoliquiritigenin Induces Autophagy and Inhibits Ovarian Cancer Cell Growth
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What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Assessment of Polyphenol Oxidase Inhibition, Antimicrobial and Antioxidant Properties of Some Chalcone Derivates: Experimental and Computational Approaches
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Synthetic Approaches to Chalcone Synthesis
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Discovery of new cyanopyridine/chalcone hybrids as dual inhibitors of EGFR/BRAFV600E with promising antiproliferative properties
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Chalcone‐based benzenesulfonamides as potent and selective inhibitors for human carbonic anhydrase II: Design, synthesis, in vitro, and in silico studies
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Design, Synthesis, and Biological Evaluation of Triazole Tethered Coumarin‐Indole Fused Chalcone‐Isatin Derivatives as a New Class of Anti‐Breast Cancer Agents
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Alantolactone as a Bioactive Sesquiterpene Lactone: Molecular Mechanisms and Anticancer Potential for Pharmaceutical Development
inferred← citeshttps://doi.org/10.1002/ardp.70291openalex-snapshot
1,2,3‐Triazole‐Linked Chalcones as Privileged Scaffolds in Anticancer Agents
inferred← citeshttps://doi.org/10.1002/cbdv.202200973openalex-snapshot
Antimicrobial, Antiproliferative Effects and Docking Studies of Methoxy Group Enriched Coumarin‐Chalcone Hybrids
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Novel Chalcone‐Phenazine Hybrids Induced Ferroptosis in U87‐MG Cells through Activating Ferritinophagy
inferred← citeshttps://doi.org/10.1002/cbdv.202402634openalex-snapshot
Prenylated Chalcones From Roots of Kidney Vetch (Anthyllis vulneraria L.) With Antiproliferative Activity
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Targeting Cancer Cells With Triazene‐Appended Morpholine Chalcones: Antiproliferative Activity and ROS‐Dependent Apoptotic Mechanisms
inferred← citeshttps://doi.org/10.1002/cbdv.202501077openalex-snapshot
Cytotoxic Activity of Opopanax hispidus (Friv.) Griseb.: Characterization of a New Chalcone‐type Compound
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Cytotoxic Profiling of 3′,4′,5′‐Trimethoxychalcones Reveals Cell‐Line‐Dependent Cytotoxic Activity: An In Vitro and In Silico Study
inferred← citeshttps://doi.org/10.1002/cbdv.71441openalex-snapshot
Synthesis, Anticancer Activity Evaluation, and Molecular Docking Studies of Some New Chalcone and Pyrazoline Derivatives
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Discovery of Alkaloid Quinazolone‐Derived Imidazolenones with Novel Structural Scaffolds of Multitargeting Antibacterial Potential
inferred← citeshttps://doi.org/10.1002/cssc.202401591openalex-snapshot
Mechanochemical Synthesis of β‐Sulfenylated Ketones and Esters
inferred← citeshttps://doi.org/10.1002/ddr.70313openalex-snapshot
Heterocyclic Scaffold Modification of Chalcones: Piperidinyl and Morpholinyl Triazene Derivatives as Potent Blood Stage Antimalarials With SAR and Docking Insights
inferred← citeshttps://doi.org/10.1002/fft2.494openalex-snapshot
Structural insights and biological activities of flavonoids: Implications for novel applications
inferred← citeshttps://doi.org/10.1002/jbt.23679openalex-snapshot
Novel furan chalcone modulates PHD‐2 induction to impart antineoplastic effect in mammary gland carcinoma
inferred← citeshttps://doi.org/10.1002/jcb.30442openalex-snapshot
Targeting the epithelial–mesenchymal transition (EMT) pathway with combination of Wnt inhibitor and chalcone complexes in lung cancer cells
inferred← citeshttps://doi.org/10.1002/jcla.70154openalex-snapshot
Synthesis, Antitumor Activity Evaluation and Mechanistic Study of Novel Bis‐Heterocyclic Chalcones Against Liver Cancer
inferred← citeshttps://doi.org/10.1002/jhet.4617openalex-snapshot
Chalcones: Versatile intermediates in heterocyclic synthesis
inferred← citeshttps://doi.org/10.1002/masy.70165openalex-snapshot
Electrochemical Synthesis of Chalcones and Ball Milling Synthesis of Graphene Nanosheets for the Fabrication of Chalcone–Graphene Macromolecular Hybrids
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Chain branching during the polycondensation of isophthalic aldehyde and 1,1′‐diacetylferrocene by the Claisen–Schmidt reaction
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The natural chalcone derivative 4‐hydroxychalcone primes tobacco immunity against TMV via Ca 2+ ‐ ROS signaling and flavonoid biosynthesis
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4′‐Hydroxychalcone Induces Ferroptosis in Glioblastoma Through the xCT / GSH / GPX4 Axis Under the Regulation of the AKT / mTORC1 / 4EBP1 Pathway
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Pharmacological Diversity of Flavonoids and Their Clinical Application Prospects in Neurological Disorders
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Design, Synthesis, Characterization, Enzyme Inhibition, Molecular Docking, and Pharmacological Evaluation of New Chalcone‐Sulfonate Derivatives Bearing Thiophene
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A Comprehensive Review of The Molecular Dynamic Study Of Chalcones, Coumarins and Chromones as Selective MAO‐B Inhibitors [2015‐Till Date]
inferred← citeshttps://doi.org/10.1002/slct.202405226openalex-snapshot
Importance of Synthesized Chalcone‐Functionality for Derivatization and Their Biological Activity
inferred← citeshttps://doi.org/10.1002/slct.202501573openalex-snapshot
Assessment of Polyphenol Oxidase Inhibition, Antibacterial, and Antioxidant Activity of Some Chalcone Derivatives: Experimental and Computational Approaches
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Pyridine‐Based Azachalcones as Potent Anti‐Breast Cancer Agents: Synthesis, In Vitro Evaluation, and In Silico Insights
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Recent Progress in the Design of Aryl/Hetaryl Chalcone Derivatives as Improved Anticancer Agents: An Insightful Review Focusing on Structure‐Activity Relationship
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Synthesis and Anticancer Evaluation of Methoxy‐Substituted Chalcone Hybrids: DFT, Molecular Docking, and ADME Studies
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New Chalcone‐Zerumbone Hybrids: Synthesis, In Vitro Anticancer Activity and Molecular Docking Study
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Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity
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Lily of the Nile (Agapanthus spp.) an Ornamental Bulbous Plant: Phytochemicals and Correlation with Breeding Aspects
inferred← citeshttps://doi.org/10.1007/978-3-642-36202-6_299-1openalex-snapshot
Medicinally Important Natural Chalcones
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New class of hybrids based on chalcone and melatonin: a promising therapeutic option for the treatment of colorectal cancer
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Synthesis, cytotoxicity, Pan-HDAC inhibitory activity and docking study of new N-(2-aminophenyl)-2-methylquinoline-4-carboxamide and (E)-N-(2-aminophenyl)-2-styrylquinoline-4-carboxamide derivatives as anticancer agents
inferred← citeshttps://doi.org/10.1007/s00044-023-03109-8openalex-snapshot
Carboxylated chalcones and related flavonoids as inhibitors of xanthine oxidase
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Bio-evaluation of the 2-nitrochalcones as potential anti-lung cancer agents, inducers of apoptosis and inhibitors of protein kinase (VEGFR-2)
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Synthesis, characterization, and anticancer activity of syringaldehyde-derived chalcones against female cancers
inferred← citeshttps://doi.org/10.1007/s00044-024-03235-xopenalex-snapshot
Synthesis and in vitro biological activity of chalcone derivatives as potential antiparasitic agents
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Chalcones as multitarget modulators in non-small cell lung cancer: mechanistic insights and therapeutic perspectives
inferred← citeshttps://doi.org/10.1007/s10123-024-00541-7openalex-snapshot
Synergistic activity between conventional antifungals and chalcone-derived compound against dermatophyte fungi and Candida spp.
inferred← citeshttps://doi.org/10.1007/s10787-023-01369-9openalex-snapshot
Recent advances in anti-inflammatory active components and action mechanisms of natural medicines
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N-Dimethyl chalcone facilitated augmentation of IL-10 and diminution of TNF-α, IL-1β, IL-6, NFκB, and COX-2 in FCA-induced arthritic rat model
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Synthesis of Ferrocenyl Chalcone-Containing Aminourea Schiff Bases and Their Detection on Tryptophan
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Synthesis, Characterization and Pharmacological Evaluation of Isoliquiritigenin Ruthenium-p-Cymene Organometallic Complex in MNNG-Induced Rat Gastric Cancer Chemotherapy: In Silico, In Vitro and In Vivo Methodologies
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Organohalogen chalcones: design, synthesis, ADMET prediction, molecular dynamics study and inhibition effect on acetylcholinesterase and carbonic anhydrase
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Antiviral activity evaluation and action mechanism of chalcone derivatives containing phenoxypyridine
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A survey of isatin hybrids and their biological properties
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Novel pyrazole–oxadiazole–chalcone/oxime hybrids as dual EGFR/VEGFR-2 inhibitors with promising anticancer potential: a comprehensive cytotoxicity evaluation, mechanistic insights and SAR analysis
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Medicinal chemistry perspective of chalcone derivatives as anticancer agents: synthetic strategy, biological activity, and structure-activity relationship
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Anticancer potential of chalcones loaded on mesoporous silica nanoparticles
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Mesoporous silica nanoparticles as nanocarriers for 2′-hydroxy-2-fluorochalcone: synthesis, characterization, and anticancer activity against colorectal cancer cells
inferred← citeshttps://doi.org/10.1007/s11172-023-3943-6openalex-snapshot
Synthesis of chalcones with methylenedioxypolymethoxy fragments based on plant metabolites and study of their antiproliferative properties
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Evaluation of Benzothiazole-Chalcone Hybrids: Apoptosis Induction, Docking Analysis, and Anticancer Potential in Gastric Cancer Cells
inferred← citeshttps://doi.org/10.1007/s13205-025-04648-0openalex-snapshot
From concept to simulations: computational and experimental assessment of thiadiazole–thiazolidinone hybrid chalcones for anti-alzheimer potentials
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Maclura tinctoria (L.) D. Don ex Steud. (Moraceae): a review of the advances in ethnobotanical knowledge, phytochemical composition, and pharmacological potential
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Benzofuran Substituted Chalcone Derivatives Trigger Apoptotic Cell Death Through Extrinsic Pathway in Human Lung and Breast Cancer Cells
inferred← citeshttps://doi.org/10.1007/s42250-024-00891-9openalex-snapshot
Synthesis, Antibacterial, Antioxidant and DFT Computational Studies of Acetophenone-Based Chalcone Derivatives
inferred← citeshttps://doi.org/10.1007/s42452-026-09492-2openalex-snapshot
A comprehensive review on synthesis and anticancer evaluation of triazole chalcone hybrids
inferred← citeshttps://doi.org/10.1007/s43440-025-00721-wopenalex-snapshot
Chalcone-9: a novel inhibitor of the JAK-STAT pathway with potent anti-cancer effects in triple-negative breast cancer cells
inferred← citeshttps://doi.org/10.1007/s43994-025-00223-8openalex-snapshot
Synthesis of new pyrimidine derivatives and study their antibacterial activity: Computational and in vitro assessment
inferred← citeshttps://doi.org/10.1016/b978-0-443-26795-6.00005-2openalex-snapshot
Plant-pathogenic interaction: flavonoid internetworking
inferred← citeshttps://doi.org/10.1016/b978-0-443-30122-3.00005-4openalex-snapshot
Chalcone-based nanomaterials: Synthesis, characterization, and applications
inferred← citeshttps://doi.org/10.1016/b978-0-443-30122-3.00006-6openalex-snapshot
Chalcones and their derivatives as anticancer agents: Mechanisms and applications
inferred← citeshttps://doi.org/10.1016/b978-0-443-30122-3.00012-1openalex-snapshot
Chalcones in drug discovery and medicinal chemistry
inferred← citeshttps://doi.org/10.1016/b978-0-443-30122-3.00015-7openalex-snapshot
Naturally occurring chalcones and their biological activities
inferred← citeshttps://doi.org/10.1016/b978-0-443-30122-3.00018-2openalex-snapshot
Chalcones in drug development: Synthesis, properties, and molecular docking insights into drug targets and biological activity
inferred← citeshttps://doi.org/10.1016/b978-0-443-30122-3.00019-4openalex-snapshot
Chalcones and their derivatives as antioxidants: Mechanism and Applications
inferred← citeshttps://doi.org/10.1016/b978-0-443-30122-3.00022-4openalex-snapshot
Exploring the anticancer potential of chalcones: Mechanistic insights and therapeutic prospects
inferred← citeshttps://doi.org/10.1016/b978-0-443-30122-3.00023-6openalex-snapshot
Chalcone incorporating metal complexes and their biomedical applications
inferred← citeshttps://doi.org/10.1016/b978-0-443-30122-3.00025-xopenalex-snapshot
Developing hybrid molecules from chalcones: Bridging structures for enhanced properties
inferred← citeshttps://doi.org/10.1016/b978-0-443-42855-5.00004-2openalex-snapshot
Flavonoids, their classification, chemistry, and therapeutic potential against various types of cancer
inferred← citeshttps://doi.org/10.1016/b978-0-443-43812-7.00013-7openalex-snapshot
Natural sources of chalcones
inferred← citeshttps://doi.org/10.1016/b978-0-443-43812-7.00018-6openalex-snapshot
Clinical trials of chalcone-based drug candidates
inferred← citeshttps://doi.org/10.1016/j.antiviral.2023.105735openalex-snapshot
Synthesis, evaluation, and mechanism of 1-(4-(arylethylenylcarbonyl)phenyl)-4-carboxy-2-pyrrolidinones as potent reversible SARS-CoV-2 entry inhibitors
inferred← citeshttps://doi.org/10.1016/j.apmt.2025.102841openalex-snapshot
Phenothiazine-functionalized cyclic chalcone derivative: aggregation-induced emission enhancement, high-contrast mechanochromic luminescence beyond 100nm, and its applications in latent fingerprint extraction, anti-counterfeiting and information encryption
inferred← citeshttps://doi.org/10.1016/j.arabjc.2023.104776openalex-snapshot
Design, synthesis and biological activity of novel chalcone derivatives containing indole
inferred← citeshttps://doi.org/10.1016/j.arabjc.2024.105758openalex-snapshot
Design, synthesis and antifungal activity of indole derivatives containing 1,3,4-oxadiazole
inferred← citeshttps://doi.org/10.1016/j.bbrc.2023.09.044openalex-snapshot
A review on Millepachine and its derivatives as potential multitarget anticancer agents
inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.152361openalex-snapshot
Anti-nucleolin aptamer-guided anticancer activity of AS1411-Chalcone conjugate in breast cancer
inferred← citeshttps://doi.org/10.1016/j.bioorg.2022.105926openalex-snapshot
Structure-activity relationships reveal a 2-furoyloxychalcone as a potent cytotoxic and apoptosis inducer for human U-937 and HL-60 leukaemia cells
inferred← citeshttps://doi.org/10.1016/j.bioorg.2022.106036openalex-snapshot
Design, synthesis, characterization and anticancer activity evaluation of deoxycholic acid-chalcone conjugates
inferred← citeshttps://doi.org/10.1016/j.bioorg.2023.106444openalex-snapshot
Design, synthesis, cytotoxic activities, and molecular docking of chalcone hybrids bearing 8-hydroxyquinoline moiety with dual tubulin/EGFR kinase inhibition
inferred← citeshttps://doi.org/10.1016/j.bioorg.2024.107498openalex-snapshot
Design, synthesis, and ex vivo anti-drug resistant cervical cancer activity of novel molecularly targeted chalcone derivatives
inferred← citeshttps://doi.org/10.1016/j.bioorg.2024.107766openalex-snapshot
Development of new LSM-83177 analogues as anti-tumor agents against colorectal cancer targeting p53-MDM2 interaction
inferred← citeshttps://doi.org/10.1016/j.bioorg.2025.108639openalex-snapshot
Design, synthesis, and in vitro and in vivo anti-drug resistant cervical cancer activity of novel licochalcone A derivatives based on dual targeting of VEGFR-2/P-gp
inferred← citeshttps://doi.org/10.1016/j.bioorg.2025.108696openalex-snapshot
Synthesis of new chalcones and pyrimidine derivatives as antidiabetic agents for type 2 diabetes mellitus: In vitro and in vivo studies
inferred← citeshttps://doi.org/10.1016/j.bioorg.2025.109006openalex-snapshot
Design and synthesis of novel quinoline-chalcone derivatives as dual inhibitors of tubulin polymerization and P-glycoprotein to overcome cisplatin resistance in cervical cancer
inferred← citeshttps://doi.org/10.1016/j.bioorg.2025.109105openalex-snapshot
Chalcones and their derivatives as inhibitors of key ABC transporters (ABCB1, ABCG2) to overcome tumor multidrug resistance
inferred← citeshttps://doi.org/10.1016/j.bioorg.2025.109429openalex-snapshot
A Phenstatin-based indole-chalcone hybrid as novel anti-inflammatory agent targeting the NLRP3 Inflammasome: Leads from computational and preclinical studies
inferred← citeshttps://doi.org/10.1016/j.bioorg.2026.109911openalex-snapshot
Conformationally adaptive benzimidazolium–chalcone hybrid salts as selective TGF-β1 inhibitors
inferred← citeshttps://doi.org/10.1016/j.bioorg.2026.110505openalex-snapshot
Discovery of new 1-aryl-3-phenylureas as promising PDGFRa and VEGFR-2 inhibitors and apoptosis inducers
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115221openalex-snapshot
2,4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone from Cleistocalyx nervosum var. paniala seeds attenuated the early stage of diethylnitrosamine and 1,2-dimethylhydrazine-induced colorectal carcinogenesis
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.116313openalex-snapshot
Targeting the JAK2/STAT3 signaling pathway with natural plants and phytochemical ingredients: A novel therapeutic method for combatting cardiovascular diseases
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.117284openalex-snapshot
Chalcones induce apoptosis, autophagy and reduce spreading in osteosarcoma 3D models
inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118076openalex-snapshot
Quinine-chalcone hybrids as potent inhibitors of P-glycoprotein with apoptotic effects on EBC-1 cells
inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118912openalex-snapshot
Discovery of novel chalcone derivatives containing benzimidazole possessing anti-tumor potential in vitro and in vivo
inferred← citeshttps://doi.org/10.1016/j.biopha.2026.119447openalex-snapshot
Design, synthesis and biological evaluation of novel chalcone analogs against castration-resistant prostate cancer
inferred← citeshttps://doi.org/10.1016/j.biopha.2026.119820openalex-snapshot
The chalcone derivative DN-053 attenuates renal fibrosis and inhibits p38 MAPK and STAT3 signaling in renal fibroblasts
inferred← citeshttps://doi.org/10.1016/j.bmc.2023.117458openalex-snapshot
A novel chalcone derivative exerts anticancer effects by promoting apoptotic cell death of human pancreatic cancer cells
inferred← citeshttps://doi.org/10.1016/j.bmc.2025.118512openalex-snapshot
Recent developments in synthesis and antimalarial activities of chalcone hybrids
inferred← citeshttps://doi.org/10.1016/j.bmc.2026.118681openalex-snapshot
Synthesis and anti-tumor activity evaluation of novel chalcone derivatives as potential HDAC6 inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmcl.2023.129467openalex-snapshot
Flexibility in the bridge of chalcone derivatives is important for the inhibition of cellular growth
inferred← citeshttps://doi.org/10.1016/j.bmcl.2024.129795openalex-snapshot
Design, synthesis, and biological evaluation of chalcone acetamide derivatives against triple negative breast cancer
inferred← citeshttps://doi.org/10.1016/j.bmcl.2026.130562openalex-snapshot
Nature-inspired chalcone-functionalized paracetamol derivatives as potential anticancer leads: synthesis, biological evaluation, apoptotic mechanisms, and in silico docking studies
inferred← citeshttps://doi.org/10.1016/j.cbi.2023.110790openalex-snapshot
4-Nitrochalcone as a potential drug in non-clinical breast cancer studies
inferred← citeshttps://doi.org/10.1016/j.cdc.2026.101229openalex-snapshot
Synthesis and Biological Evaluation of chalcone derivatives of [1,2,4]triazolo[4,3-a]pyridines as Anticancer Agents
inferred← citeshttps://doi.org/10.1016/j.chphi.2025.100886openalex-snapshot
Novel Al(OH)3 and Ti/Fe@Al(OH)3 nano catalyzed of N-(3-((E)-3-(4-Adamant-1-yl)-phenyl) acryloyl) phenyl) quinoline-2-carboxamide Synthesis and its Molecular Docking, Quantum chemical Studies
inferred← citeshttps://doi.org/10.1016/j.comptc.2025.115380openalex-snapshot
Chalcones from the deep: in silico medicinal chemistry and quantum chemical insights into their anticancer and anti-HIV potency
inferred← citeshttps://doi.org/10.1016/j.cyto.2026.157185openalex-snapshot
The multifaceted role of acetamide derivative of chalcone: Anti-inflammatory action and impact on osteoclastogenesis, insights on NF-κB and MAPK pathway
inferred← citeshttps://doi.org/10.1016/j.ejmcr.2025.100309openalex-snapshot
Flavonoid-mediated modulation of Tau protein: Implications for targeted therapeutics and clinical relevance in Tau-related disorders
inferred← citeshttps://doi.org/10.1016/j.ejmech.2022.114851openalex-snapshot
Design, synthesis and biological evaluation of a new series of arylidene indanones as small molecules for targeted therapy of non-small cell lung carcinoma and prostate cancer
inferred← citeshttps://doi.org/10.1016/j.ejmech.2024.116933openalex-snapshot
Green synthesis of neuroprotective spirocyclic chalcone derivatives and their role in protecting against traumatic optic nerve injury
inferred← citeshttps://doi.org/10.1016/j.ejmech.2025.117963openalex-snapshot
Amino acid–modified chalcone derivatives with in vitro and in vivo efficacy against colon cancer
inferred← citeshttps://doi.org/10.1016/j.ejphar.2025.178499openalex-snapshot
Recent advances in antitumor indole-chalcone derivatives: a mini review
inferred← citeshttps://doi.org/10.1016/j.fct.2023.114415openalex-snapshot
Chalcones from plants cause toxicity by inhibiting human and rat 11β-hydroxysteroid dehydrogenase 2: 3D-quantitative structure-activity relationship (3D-QSAR) and in silico docking analysis
inferred← citeshttps://doi.org/10.1016/j.fitote.2023.105458openalex-snapshot
Synthesis and biological activities of novel chalcone derivatives containing pyrazole oxime ethers
inferred← citeshttps://doi.org/10.1016/j.fochx.2026.104340openalex-snapshot
Metabolomic analysis reveals flavonoid accumulation patterns in four apricot cultivars
inferred← citeshttps://doi.org/10.1016/j.foodchem.2022.132531openalex-snapshot
Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e37147openalex-snapshot
Bis-chalcones obtained via one-pot synthesis as the anti-neurodegenerative agents and their effect on the HT-22 cell line
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2022.04.076openalex-snapshot
Transcription factor Fli-1 as a new target for antitumor drug development
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.134832openalex-snapshot
A comprehensive review on recent xanthine oxidase inhibitors of dietary based bioactive substances for the treatment of hyperuricemia and gout: Molecular mechanisms and perspective
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.137009openalex-snapshot
Chalcones as potential pepsin inhibitors: Synthesis, characterization, DFT and molecular docking studies
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.138530openalex-snapshot
In vitro anticancer effects in hepatocellular carcinoma (HCC) and protein interaction study of xanthoangelol
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.111959openalex-snapshot
Ononin triggers ferroptosis-mediated disruption in the triple negative breast cancer both in vitro and in vivo
inferred← citeshttps://doi.org/10.1016/j.isci.2025.114057openalex-snapshot
Sappanchalcone suppresses NSCLC by oxidative stress-driven DNA damage and ER stress activation through PIEZO1 modulation
inferred← citeshttps://doi.org/10.1016/j.jare.2025.08.034openalex-snapshot
The advent of precision nutrigeroscience in cancer: from clinic towards molecular biology
inferred← citeshttps://doi.org/10.1016/j.jfluchem.2026.110591openalex-snapshot
Reactions of polyfluorinated chalcones with hydroxylamine and subsequent intramolecular cyclization
inferred← citeshttps://doi.org/10.1016/j.jics.2026.102878openalex-snapshot
Synthesis, spectroscopic characterization, biological activities, and molecular docking studies of novel furan-based azo- and ester-functionalized chalcone derivatives
inferred← citeshttps://doi.org/10.1016/j.jorganchem.2023.122640openalex-snapshot
Green synthesis of ferrocenyl chalcones against triple negative breast cancer
inferred← citeshttps://doi.org/10.1016/j.jorganchem.2025.123528openalex-snapshot
Probing the fascinating role of Eu-AgNPs in the synthesis of bioactive substituted chalcones as a green matrix and study of their biological potential
inferred← citeshttps://doi.org/10.1016/j.jphotochem.2024.115511openalex-snapshot
D-A-D/A chalcones with tunable optical characteristics: Synthesis, photophysical, electrochemical and theoretical investigations
inferred← citeshttps://doi.org/10.1016/j.jphotochem.2026.117634openalex-snapshot
Exploring excited state dynamics and two-photon absorption response in synthetic β-chalcone-substituted tetraphenylporphyrins derivatives
inferred← citeshttps://doi.org/10.1016/j.jscs.2023.101791openalex-snapshot
Design, synthesis, and antifungal activities of chalcone derivatives containing piperidine and sulfonamide moiety
inferred← citeshttps://doi.org/10.1016/j.lddd.2026.100521openalex-snapshot
Design and synthesis of an anthracene-chalcone derivative as a novel carbonic anhydrase II inhibitor: A combined DFT, molecular docking and dynamic simulation study
inferred← citeshttps://doi.org/10.1016/j.matdes.2023.112624openalex-snapshot
Hollow porous PLA/PBAT composite microfibers with enhanced toughness and prolonged drug release for wound healing
inferred← citeshttps://doi.org/10.1016/j.molliq.2024.124561openalex-snapshot
Exploring 4-chloro chalcone: Synthesis, spectroscopic, chemical reactivity, topological, hirshfeld surface, drug-Likeness, molecular docking and assessment of electronic properties in diverse solvents
inferred← citeshttps://doi.org/10.1016/j.molstruc.2022.134009openalex-snapshot
AIEgens-NLOphores coumarin-triphenylamine chalcone derivatives: Synthesis, photophysical properties and DFT computational study
inferred← citeshttps://doi.org/10.1016/j.molstruc.2022.134226openalex-snapshot
Structural investigations and theoretical insights of a polymethoxy chalcone derivative: Synthesis, crystal structure, 3D energy frameworks and SARS CoV-2 docking studies
inferred← citeshttps://doi.org/10.1016/j.molstruc.2023.135785openalex-snapshot
Synthesis and biological evaluation of bis-chalcone conjugates containing lysine linker as potential anticancer agents
inferred← citeshttps://doi.org/10.1016/j.molstruc.2023.136244openalex-snapshot
Chalcone-based dipolar cycloaddition of novel heteroaromatic compounds: Their anticancer examination
inferred← citeshttps://doi.org/10.1016/j.molstruc.2023.136620openalex-snapshot
2-(allylthio)-5-(5-phenyl-1H-pyrazol-3-yl)-1,3,4-oxadiazole: Synthesis, single crystal XRD, spectroscopic characterization, antidiabetic activity, DFT and ADMET studies
inferred← citeshttps://doi.org/10.1016/j.molstruc.2023.136857openalex-snapshot
Novel diphenyl ether-heterocycles hybrids: Synthesis via Hantzsch and Biginelli reactions, molecular docking simulation, and antimicrobial activities
inferred← citeshttps://doi.org/10.1016/j.molstruc.2024.137748openalex-snapshot
Synthesis, isomorphism, and polymorphism of new (2E,4E)-1-(5-methyl-1-aryl-1H-1,2,3-triazol-4-yl)-5-phenylpenta-2,4-dien-1-ones
inferred← citeshttps://doi.org/10.1016/j.molstruc.2024.138691openalex-snapshot
Unlocking the potential of icaritin derivatives: Synthesis, characterization, and antiproliferative activity against MCF-7 breast cancer cells
inferred← citeshttps://doi.org/10.1016/j.molstruc.2024.138890openalex-snapshot
Chalcone-benzyloxy phenyl hybrids with electron donating substituents: Crystal structure and anticancer efficacy
inferred← citeshttps://doi.org/10.1016/j.molstruc.2024.139648openalex-snapshot
Semisynthesis of novel chalcone hybrid compounds linked by 1,2,3-triazole and evaluation of their cytotoxic effects
inferred← citeshttps://doi.org/10.1016/j.molstruc.2024.139992openalex-snapshot
Microwave-assisted synthesis, antiproliferative, antibacterial activities, in silico, computational studies and molecular dynamics simulation of new bis-(aryl-based chalcone) derivatives
inferred← citeshttps://doi.org/10.1016/j.molstruc.2025.141506openalex-snapshot
Design and synthesis of new anti-cervical cancer compounds, including pyridines, indoles, naphthalenes, and pyrrolopyridines derived from chalcone derivatives
inferred← citeshttps://doi.org/10.1016/j.molstruc.2025.141748openalex-snapshot
Multi-targeted thiophene based effective digestive enzyme inhibitors: Synthesis and enzyme inhibition studies
inferred← citeshttps://doi.org/10.1016/j.molstruc.2025.142469openalex-snapshot
Unveiling the multifunctionality of chalcone-based organic crystal: A study on nonlinear optics, photoluminescence, and molecular simulations
inferred← citeshttps://doi.org/10.1016/j.molstruc.2025.143101openalex-snapshot
ADME predictions and molecular docking insights for novel Gypsogenin–chalcone hybrids and chalcones as antitumor and antimicrobial agents
inferred← citeshttps://doi.org/10.1016/j.molstruc.2025.143182openalex-snapshot
Synthesis and molecular modeling of new pyrazolyl-thiazolines and evaluating their anticancer activity
inferred← citeshttps://doi.org/10.1016/j.molstruc.2025.144184openalex-snapshot
Synthesis, characterization, anticancer activity of novel chalcone derivatives and the efficacy of electroporation
inferred← citeshttps://doi.org/10.1016/j.molstruc.2026.145775openalex-snapshot
Synthesis, characterization, molecular docking and anti-corrosion activities of new pyrimidine derivatives
inferred← citeshttps://doi.org/10.1016/j.molstruc.2026.147422openalex-snapshot
Recent Advances in the Synthesis and Biological Applications of Chalcone Derivatives: A Comprehensive Review
inferred← citeshttps://doi.org/10.1016/j.molstruc.2026.147545openalex-snapshot
Novel functionalized chalcone-appended styryldihydroacridinone molecular hybrids: Synthesis, spectroscopic characterization, and crystallographic insights from ESP and Hirshfeld surface analysis
inferred← citeshttps://doi.org/10.1016/j.neuint.2024.105859openalex-snapshot
A critical appraisal of geroprotective activities of flavonoids in terms of their bio-accessibility and polypharmacology
inferred← citeshttps://doi.org/10.1016/j.nxmate.2026.101913openalex-snapshot
Cytotoxicity effects induced by silver and 4-chlorochalcone nanoparticles synthesized using Mentha spicata L. on breast cancer MDA-MB-231, MCF-7 cell lines and healthy MRC-5 fibroblasts
inferred← citeshttps://doi.org/10.1016/j.optmat.2024.115039openalex-snapshot
Carboxy-substituted D-π-A arylated chalcones: Synthesis, photophysical properties and preliminary evaluation as photosensitizers for DSSCs
inferred← citeshttps://doi.org/10.1016/j.phymed.2022.154087openalex-snapshot
A chalcone-syringaldehyde hybrid inhibits triple-negative breast cancer cell proliferation and migration by inhibiting CKAP2-mediated FAK and STAT3 phosphorylation
inferred← citeshttps://doi.org/10.1016/j.phyplu.2026.100971openalex-snapshot
Exploration of the therapeutic potential of Bidens pilosa in the management of prostate cancer
inferred← citeshttps://doi.org/10.1016/j.rechem.2023.101279openalex-snapshot
Design, synthesis and in silico docking techniques of new 1,2,3-triazolylpyrrolidines bearing chalcone derivatives: Discovery of potent antitubercular agents
inferred← citeshttps://doi.org/10.1016/j.rechem.2024.101536openalex-snapshot
An efficient synthesis and anticancer evaluation of 1,2,3-triazolo-indole-2-carboxylate derivatives
inferred← citeshttps://doi.org/10.1016/j.rechem.2024.101633openalex-snapshot
Pyridine-based chalcones as promising anticancer agents: Design, synthesis and in silico studies
inferred← citeshttps://doi.org/10.1016/j.rechem.2025.102683openalex-snapshot
A dual-targeted attack: 2-benzofuran chalcone–tamoxifen combination induces apoptosis and suppresses metastatic behavior in ER+ breast cancer
inferred← citeshttps://doi.org/10.1016/j.saa.2023.123180openalex-snapshot
Substituent and solvent effects on UV‐visible absorption spectra of chalcones derivatives: Experimental and computational studies
inferred← citeshttps://doi.org/10.1016/j.saa.2023.123362openalex-snapshot
Binding studies of potential amyloid-β inhibiting chalcone derivative with bovine serum albumin
inferred← citeshttps://doi.org/10.1016/j.tetlet.2022.154220openalex-snapshot
I2/TBHP-mediated tandem cyclization and oxidation reaction: Facile access to 2,5-disubstituted oxazoles
inferred← citeshttps://doi.org/10.1016/j.toxrep.2025.102120openalex-snapshot
Butein mitigates 5-FU-triggered hepatotoxicity via antioxidant, anti-inflammatory, and anti-apoptotic pathways
inferred← citeshttps://doi.org/10.1016/j.yexcr.2026.115070openalex-snapshot
A novel chalcone analog inhibits cancer stemness in CD44+ and CD133+ populations via suppression of ERK signaling
inferred← citeshttps://doi.org/10.1021/acs.accounts.2c00583openalex-snapshot
Chalcones: Potential Chemotherapeutic Compounds and Educational Tools for Closing the Loop in STEM
inferred← citeshttps://doi.org/10.1021/acs.joc.5c02788openalex-snapshot
Visible-Light-Driven Copper Catalysis: A Green and Sustainable Approach to Chlorohydroxylation of Chalcones
inferred← citeshttps://doi.org/10.1021/acs.orglett.4c03160openalex-snapshot
Rhodium-Catalyzed Synthesis of Trifluoromethyl-Containing Allylic Alcohols Via Z-Alkenyl Transfer with High Stereochemistry Retention
inferred← citeshttps://doi.org/10.1021/acscatal.2c04131openalex-snapshot
Well-Defined Bis(NHC)Mn(I) Complex Catalyzed Tandem Transformation of α,β-Unsaturated Ketones to α-Methylated Ketones Using Methanol
inferred← citeshttps://doi.org/10.1021/acschemneuro.2c00778openalex-snapshot
New Benzodihydrofuran Derivatives Alter the Amyloid β Peptide Aggregation: Strategies To Develop New Anti-Alzheimer Drugs
inferred← citeshttps://doi.org/10.1021/acsomega.2c01779openalex-snapshot
Synthesis of Chalcones Derivatives and Their Biological Activities: A Review
inferred← citeshttps://doi.org/10.1021/acsomega.2c02181openalex-snapshot
Newly Synthesized Pyrazolinone Chalcones as Anticancer Agents via Inhibiting the PI3K/Akt/ERK1/2 Signaling Pathway
inferred← citeshttps://doi.org/10.1021/acsomega.2c07625openalex-snapshot
Thiocarbohydrazone and Chalcone-Derived 3,4-Dihydropyrimidinethione as Lipid Peroxidation and Soybean Lipoxygenase Inhibitors
inferred← citeshttps://doi.org/10.1021/acsomega.3c02478openalex-snapshot
Cyclization of Chalcone Derivatives: Design, Synthesis, In Silico Docking Study, and Biological Evaluation of New Quinazolin-2,4-diones Incorporating Five-, Six-, and Seven-Membered Ring Moieties as Potent Antibacterial Inhibitors
inferred← citeshttps://doi.org/10.1021/acsomega.5c02394openalex-snapshot
Synthesis and Evaluation of Novel Bis-Chalcone Derivatives Containing a Thiophene Moiety as Potential Anticancer Agents: In Vitro, In Silico , and Mechanistic Studies
inferred← citeshttps://doi.org/10.1021/acsomega.5c08480openalex-snapshot
Design and Synthesis of Novel Chalcone Derivatives Targeting Bladder and Liver Cancer: Cytotoxicity Evaluation and Preliminary Mechanistic Studies
inferred← citeshttps://doi.org/10.1021/acsomega.5c08566openalex-snapshot
Enhanced Anticancer Activity of Ibuprofen and 2′-Hydroxy-2,3,5′-trimethoxychalcone-Linked Polymeric Micelles in HeLa Cells
inferred← citeshttps://doi.org/10.1021/acsomega.5c08888openalex-snapshot
Transition-Metal-Free One-Pot Synthesis of (Hetero)chalcones with Cysteine Protease Inhibitory Activity
inferred← citeshttps://doi.org/10.1021/acssuschemeng.3c01104openalex-snapshot
Base-Free Transfer Hydrogenation Catalyzed by Ruthenium Hydride Complexes of Coumarin-Amide Ligands
inferred← citeshttps://doi.org/10.1038/s41392-022-01104-wopenalex-snapshot
Dietary regulation in health and disease
inferred← citeshttps://doi.org/10.1038/s41598-022-07691-6openalex-snapshot
Novel chalcone-derived pyrazoles as potential therapeutic agents for the treatment of non-small cell lung cancer
inferred← citeshttps://doi.org/10.1038/s41598-024-76459-xopenalex-snapshot
Design, in silico studies and biological evaluation of novel chalcones tethered triazolo[3,4-a]isoquinoline as EGFR inhibitors targeting resistance in non-small cell lung cancer
inferred← citeshttps://doi.org/10.1038/s41598-025-14360-xopenalex-snapshot
Synthesis of carbonyl-functionalized mercaptosilsesquioxane
inferred← citeshttps://doi.org/10.1038/s41598-025-15999-2openalex-snapshot
Chalcone constituents pulincisones A-F isolated from Pulicaria incisa with NQO1 inducer activity
inferred← citeshttps://doi.org/10.1038/s41598-026-49500-4openalex-snapshot
Synthesis, DFT and photophysical studies of a new thiophene-fused naphthalene chalcone
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