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Clinical Significance and Immune Infiltration Analyses of the Cuproptosis-Related Human Copper Proteome in Gastric Cancer

https://doi.org/10.3390/biom12101459
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/2211-5463.12060openalex-snapshot
Transcriptome analysis of copper homeostasis genes reveals coordinated upregulation of SLC 31A1, SCO 1, and COX 11 in colorectal cancer
inferredcites →https://doi.org/10.1007/978-1-4939-7493-1_12openalex-snapshot
Profiling Tumor Infiltrating Immune Cells with CIBERSORT
inferredcites →https://doi.org/10.1007/s10120-016-0601-9openalex-snapshot
Proposal of a new stage grouping of gastric cancer for TNM classification: International Gastric Cancer Association staging project
inferredcites →https://doi.org/10.1007/s10120-021-01207-3openalex-snapshot
Tumor mutation burden is correlated with response and prognosis in microsatellite-stable (MSS) gastric cancer patients undergoing neoadjuvant chemotherapy
inferredcites →https://doi.org/10.1016/j.biopha.2019.109595openalex-snapshot
Pyroptosis: A new frontier in cancer
inferredcites →https://doi.org/10.1016/j.ccell.2018.03.018openalex-snapshot
Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer
inferredcites →https://doi.org/10.1016/j.immuni.2018.03.014openalex-snapshot
Regulation and Function of the PD-L1 Checkpoint
inferredcites →https://doi.org/10.1016/j.molcel.2020.05.014openalex-snapshot
Cell Death in the Origin and Treatment of Cancer
inferredcites →https://doi.org/10.1016/s0140-6736(21)00797-2openalex-snapshot
First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a randomised, open-label, phase 3 trial
inferredcites →https://doi.org/10.1016/s1074-5521(97)90241-6openalex-snapshot
Copper-binding motifs in catalysis, transport, detoxification and signaling
inferredcites →https://doi.org/10.1016/s1470-2045(21)00692-6openalex-snapshot
Nivolumab plus chemotherapy versus placebo plus chemotherapy in patients with HER2-negative, untreated, unresectable advanced or recurrent gastric or gastro-oesophageal junction cancer (ATTRACTION-4): a randomised, multicentre, double-blind, placebo-controlled, phase 3 trial
inferredcites →https://doi.org/10.1038/ncomms3612openalex-snapshot
Inferring tumour purity and stromal and immune cell admixture from expression data
inferredcites →https://doi.org/10.1038/s41419-019-1441-4openalex-snapshot
Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells
inferredcites →https://doi.org/10.1038/s41587-019-0114-2openalex-snapshot
Determining cell type abundance and expression from bulk tissues with digital cytometry
inferredcites →https://doi.org/10.1038/s41598-019-43924-xopenalex-snapshot
FN1, SPARC, and SERPINE1 are highly expressed and significantly related to a poor prognosis of gastric adenocarcinoma revealed by microarray and bioinformatics
inferredcites →https://doi.org/10.1038/s41598-022-15251-1openalex-snapshot
A novel Cuproptosis-related LncRNA signature to predict prognosis in hepatocellular carcinoma
inferredcites →https://doi.org/10.1038/s43018-021-00247-zopenalex-snapshot
Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer
inferredcites →https://doi.org/10.1039/c6mt00202aopenalex-snapshot
Defining the human copper proteome and analysis of its expression variation in cancers
inferredcites →https://doi.org/10.1074/jbc.m706563200openalex-snapshot
The Copper Binding Domain of SPARC Mediates Cell Survival in Vitro via Interaction with Integrin β1 and Activation of Integrin-linked Kinase
inferredcites →https://doi.org/10.1080/21655979.2022.2038434openalex-snapshot
Disulfiram/Copper induces antitumor activity against gastric cancer via the ROS/MAPK and NPL4 pathways
inferredcites →https://doi.org/10.1111/cpr.12568openalex-snapshot
Blockage of SLC31A1‐dependent copper absorption increases pancreatic cancer cell autophagy to resist cell death
inferredcites →https://doi.org/10.1126/sciadv.aay4211openalex-snapshot
Multi-omics characterization of molecular features of gastric cancer correlated with response to neoadjuvant chemotherapy
inferredcites →https://doi.org/10.1126/science.aaa1348openalex-snapshot
Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer
inferredcites →https://doi.org/10.1126/science.aaw9872openalex-snapshot
Cysteine depletion induces pancreatic tumor ferroptosis in mice
inferredcites →https://doi.org/10.1126/science.abf0529openalex-snapshot
Copper induces cell death by targeting lipoylated TCA cycle proteins
inferredcites →https://doi.org/10.1136/bmj.k3529openalex-snapshot
Efficacy of PD-1 or PD-L1 inhibitors and PD-L1 expression status in cancer: meta-analysis
inferredcites →https://doi.org/10.1136/jitc-2021-003414openalex-snapshot
Genomic and transcriptomic characterization of heterogeneous immune subgroups of microsatellite instability-high colorectal cancers
inferredcites →https://doi.org/10.1136/jitc-2021-003984openalex-snapshot
Effect of neoadjuvant chemotherapy on the immune microenvironment in gastric cancer as determined by multiplex immunofluorescence and T cell receptor repertoire analysis
inferredcites →https://doi.org/10.1159/000453569openalex-snapshot
PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer
inferredcites →https://doi.org/10.1159/000489558openalex-snapshot
Significance of the Lysyl Oxidase Members Lysyl Oxidase Like 1, 3, and 4 in Gastric Cancer
inferredcites →https://doi.org/10.1186/s12885-017-3738-yopenalex-snapshot
Diagnostic and prognostic value of CEA, CA19–9, AFP and CA125 for early gastric cancer
inferredcites →https://doi.org/10.1186/s12935-019-0801-6openalex-snapshot
A new Schiff base coordinated copper(II) compound induces apoptosis and inhibits tumor growth in gastric cancer
inferredcites →https://doi.org/10.1200/jco.2022.40.4_suppl.244openalex-snapshot
Neoadjuvant nivolumab plus ipilimumab and adjuvant nivolumab in patients (pts) with localized microsatellite instability-high (MSI)/mismatch repair deficient (dMMR) oeso-gastric adenocarcinoma (OGA): The GERCOR NEONIPIGA phase II study.
inferredcites →https://doi.org/10.1200/jco.22.00686openalex-snapshot
Neoadjuvant Nivolumab Plus Ipilimumab and Adjuvant Nivolumab in Localized Deficient Mismatch Repair/Microsatellite Instability–High Gastric or Esophagogastric Junction Adenocarcinoma: The GERCOR NEONIPIGA Phase II Study
inferredcites →https://doi.org/10.1245/s10434-010-1039-7openalex-snapshot
Peritoneal Carcinomatosis from Gastric Cancer: A Multi-Institutional Study of 159 Patients Treated by Cytoreductive Surgery Combined with Perioperative Intraperitoneal Chemotherapy
inferredcites →https://doi.org/10.21147/j.issn.1000-9604.2020.06.03openalex-snapshot
Gastric cancer: Epidemiology, risk factors and prevention strategies
inferredcites →https://doi.org/10.3322/caac.21660openalex-snapshot
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
inferredcites →https://doi.org/10.3389/fcell.2021.760470openalex-snapshot
lncRNA/miR-29c-Mediated High Expression of LOX Can Influence the Immune Status and Chemosensitivity and Can Forecast the Poor Prognosis of Gastric Cancer
inferredcites →https://doi.org/10.3389/fonc.2022.808817openalex-snapshot
Focal Adhesion-Related Signatures Predict the Treatment Efficacy of Chemotherapy and Prognosis in Patients with Gastric Cancer
inferredcites →https://doi.org/10.3390/genes13050851openalex-snapshot
A Novel Cuproptosis-Related Prognostic Gene Signature and Validation of Differential Expression in Clear Cell Renal Cell Carcinoma
inferredcites →https://doi.org/10.3390/genes9010016openalex-snapshot
SNCA Is a Functionally Low-Expressed Gene in Lung Adenocarcinoma
inferredcites →https://doi.org/10.3748/wjg.v24.i2.266openalex-snapshot
Predictive and prognostic value of serum AFP level and its dynamic changes in advanced gastric cancer patients with elevated serum AFP
inferredcites →https://doi.org/10.5114/pg.2018.80001openalex-snapshot
Epidemiology of gastric cancer: global trends, risk factors and prevention

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4772539openalex-extracted
Predicting Immunotherapy Efficacy with Machine Learning in Gastrointestinal Cancers: A Systematic Review and Meta-Analysis
inferred← citeshttps://doi.org/10.1007/s00432-023-04916-7openalex-snapshot
A novel copper-induced cell death-related lncRNA prognostic signature associated with immune infiltration and clinical value in gastric cancer
inferred← citeshttps://doi.org/10.1007/s10534-026-00786-xopenalex-snapshot
The role of metal ions iron, copper, and zinc in the immune microenvironment of gastric cancer
inferred← citeshttps://doi.org/10.1016/j.bbrep.2023.101466openalex-snapshot
Copper-binding proteins genes set predicting the overall survival and immune infiltration in hepatocellular carcinoma by bioinformatic analysis
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2024.122805openalex-snapshot
Harnessing nanomaterials for copper-induced cell death
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.114883openalex-snapshot
Novel targets for gastric cancer: The tumor microenvironment (TME), N6-methyladenosine (m6A), pyroptosis, autophagy, ferroptosis and cuproptosis
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.117100openalex-snapshot
The functions of cuproptosis in gastric cancer: therapy, diagnosis, prognosis
inferred← citeshttps://doi.org/10.1080/15384047.2026.2644674openalex-snapshot
The role of copper and cuproptosis in digestive system cancers: novel therapeutic strategies and mechanistic insights
inferred← citeshttps://doi.org/10.1111/jcmm.70611openalex-snapshot
Copper Homeostasis, Emerging Central Players in Cancer Immunotherapy
inferred← citeshttps://doi.org/10.18240/ijo.2025.09.04openalex-snapshot
Cuproptosis-related signature and immune infiltration in age-related macular degeneration
inferred← citeshttps://doi.org/10.21037/jgo-23-62openalex-snapshot
A cuproptosis-related signature for predicting the prognosis of gastric cancer
inferred← citeshttps://doi.org/10.21037/jgo-23-946openalex-snapshot
Multi-omics analysis of the prognostic and biological role of cuproptosis-related gene in gastric cancer
inferred← citeshttps://doi.org/10.3389/fimmu.2024.1435651openalex-snapshot
The role of cuproptosis in gastric cancer
inferred← citeshttps://doi.org/10.3389/fphar.2023.1288492openalex-snapshot
The role of ARL4C in predicting prognosis and immunotherapy drug susceptibility in pan-cancer analysis
inferred← citeshttps://doi.org/10.3389/fphar.2025.1664200openalex-snapshot
The role of cuproptosis in the occurrence and development of gastric cancer
inferred← citeshttps://doi.org/10.3390/biom13060904openalex-snapshot
Gasdermin D Plays an Oncogenic Role in Glioma and Correlates to an Immunosuppressive Microenvironment
inferred← citeshttps://doi.org/10.3390/cells12030349openalex-snapshot
Copper Death Inducer, FDX1, as a Prognostic Biomarker Reshaping Tumor Immunity in Clear Cell Renal Cell Carcinoma
inferred← citeshttps://doi.org/10.3390/ijms26135937openalex-snapshot
Predicting Immunotherapy Efficacy with Machine Learning in Gastrointestinal Cancers: A Systematic Review and Meta-Analysis
inferred← citeshttps://doi.org/10.3390/jcm12062243openalex-snapshot
A Five Glutamine-Associated Signature Predicts Prognosis of Prostate Cancer and Links Glutamine Metabolism with Tumor Microenvironment
inferred← citeshttps://doi.org/10.3390/jpm15050166openalex-snapshot
Beyond Biomarkers: Machine Learning-Driven Multiomics for Personalized Medicine in Gastric Cancer
inferred← citeshttps://doi.org/10.3892/mmr.2025.13550openalex-snapshot
NLRP3 inflammasome expression affects immune cell infiltration and clinical prognosis in Helicobacter pylori infection‑associated gastric cancer
inferred← citeshttps://doi.org/10.7150/jca.94588openalex-snapshot
Copper-binding protein modelling by single-cell transcriptome and Bulk transcriptome to predict overall survival in lung adenocarcinoma patients
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