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Momordicine-I, a Bitter Melon Bioactive Metabolite, Displays Anti-Tumor Activity in Head and Neck Cancer Involving c-Met and Downstream Signaling
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1007/s11095-010-0057-2openalex-snapshot
Bitter Melon: Antagonist to Cancer
inferredcites →https://doi.org/10.1016/j.bmc.2018.08.020openalex-snapshot
Development of matrix metalloproteinase-13 inhibitors – A structure-activity/structure-property relationship study
inferredcites →https://doi.org/10.1016/j.coms.2014.01.001openalex-snapshot
Epidemiologic Trends in Head and Neck Cancer and Aids in Diagnosis
inferredcites →https://doi.org/10.1016/j.phymed.2011.06.019openalex-snapshot
Saponins from the traditional medicinal plant Momordica charantia stimulate insulin secretion in vitro
inferredcites →https://doi.org/10.1016/j.semcancer.2016.07.002openalex-snapshot
Promise of bitter melon ( Momordica charantia ) bioactives in cancer prevention and therapy
inferredcites →https://doi.org/10.1016/s0891-5849(02)00911-5openalex-snapshot
Inhibition of cancer growth by resveratrol is related to its low bioavailability
inferredcites →https://doi.org/10.1016/s1875-5364(16)60002-xopenalex-snapshot
Bitter melon: a panacea for inflammation and cancer
inferredcites →https://doi.org/10.1038/s41368-020-0084-8openalex-snapshot
Immune checkpoint pathways in immunotherapy for head and neck squamous cell carcinoma
inferredcites →https://doi.org/10.1038/s41419-019-1769-9openalex-snapshot
Clinical update on head and neck cancer: molecular biology and ongoing challenges
inferredcites →https://doi.org/10.1055/s-0034-1382837openalex-snapshot
Transport in Caco-2 Cell Monolayers of Antidiabetic Cucurbitane Triterpenoids from Momordica charantia Fruits
inferredcites →https://doi.org/10.1074/jbc.273.11.6132openalex-snapshot
Autoregulation of the Stat3 Gene through Cooperation with a cAMP-responsive Element-binding Protein
inferredcites →https://doi.org/10.1083/jcb.200806076openalex-snapshot
Receptor trafficking controls weak signal delivery: a strategy used by c-Met for STAT3 nuclear accumulation
inferredcites →https://doi.org/10.1155/2018/3939714openalex-snapshot
Inhibitory Effects of Momordicine I on High‐Glucose‐Induced Cell Proliferation and Collagen Synthesis in Rat Cardiac Fibroblasts
inferredcites →https://doi.org/10.1158/1940-6207.capr-17-0046openalex-snapshot
Bitter Melon Enhances Natural Killer–Mediated Toxicity against Head and Neck Cancer Cells
inferredcites →https://doi.org/10.1158/1940-6207.capr-17-0237openalex-snapshot
Bitter Melon Prevents the Development of 4-NQO–Induced Oral Squamous Cell Carcinoma in an Immunocompetent Mouse Model by Modulating Immune Signaling
inferredcites →https://doi.org/10.1177/1758834011422556openalex-snapshot
An overview of the c-MET signaling pathway
inferredcites →https://doi.org/10.1186/s12964-019-0447-yopenalex-snapshot
Inhibition of the key metabolic pathways, glycolysis and lipogenesis, of oral cancer by bitter melon extract
inferredcites →https://doi.org/10.1248/cpb.32.2044openalex-snapshot
Structures of momordicines I, II and III, the bitter principles in the leaves and vines of Momordica charantia L.
inferredcites →https://doi.org/10.1371/journal.pone.0078006openalex-snapshot
Bitter Melon Reduces Head and Neck Squamous Cell Carcinoma Growth by Targeting c-Met Signaling
inferredcites →https://doi.org/10.15252/embr.202051042openalex-snapshot
Long non‐coding RNA ELDR enhances oral cancer growth by promoting ILF3‐cyclin E1 signaling
inferredcites →https://doi.org/10.18632/oncotarget.19887openalex-snapshot
Bitter melon extract inhibits breast cancer growth in preclinical model by inducing autophagic cell death
inferredcites →https://doi.org/10.18632/oncotarget.8898openalex-snapshot
Immunomodulatory role of bitter melon extract in inhibition of head and neck squamous cell carcinoma growth
inferredcites →https://doi.org/10.2174/1389203719666180622095800openalex-snapshot
Emerging Antitumor Activities of the Bitter Melon (Momordica charantia)
inferredcites →https://doi.org/10.2174/187152012803833026openalex-snapshot
Plants vs. Cancer: A Review on Natural Phytochemicals in Preventing and Treating Cancers and Their Druggability
inferredcites →https://doi.org/10.3109/13880209.2013.832334openalex-snapshot
Pharmacokinetics, biodistribution and bioavailability of isoliquiritigenin after intravenous and oral administration
inferredcites →https://doi.org/10.3389/fphar.2019.01614openalex-snapshot
Phytochemicals in Cancer Treatment: From Preclinical Studies to Clinical Practice
inferredcites →https://doi.org/10.3390/cancers12082064openalex-snapshot
Bitter Melon (Momordica Charantia), a Nutraceutical Approach for Cancer Prevention and Therapy
inferredcites →https://doi.org/10.3390/cancers9040039openalex-snapshot
Hepatocyte Growth Factor/c-Met Signaling in Head and Neck Cancer and Implications for Treatment
inferredcites →https://doi.org/10.3390/cancers9060058openalex-snapshot
The Therapeutic Targeting of HGF/c-Met Signaling in Hepatocellular Carcinoma: Alternative Approaches
inferredcites →https://doi.org/10.3390/cancers9120169openalex-snapshot
Activated HGF-c-Met Axis in Head and Neck Cancer
inferredcites →https://doi.org/10.3390/ijms18122555openalex-snapshot
Recent Advances in Momordica charantia: Functional Components and Biological Activities
inferredcites →https://doi.org/10.3892/ijo.2011.957openalex-snapshot
Antitumor activity of a novel small molecule STAT3 inhibitor against a human lymphoma cell line with high STAT3 activation
inferredcites →https://doi.org/10.5681/apb.2014.062openalex-snapshot
Herbal Medicine as Inducers of Apoptosis in Cancer Treatment
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4167472openalex-extracted
Health Promoting Compounds Synthesis Affected by Stimulants in Bitter Squash (Jounpouri Cultivar)
inferred← citeshttps://doi.org/10.1002/cbdv.202400072openalex-snapshot
Antitussive, Expectorant and Antipyretic Effect of the Ethanolic Extract of the Leaves of Momordica charantia L.
inferred← citeshttps://doi.org/10.1007/s12633-025-03464-8openalex-snapshot
Polysaccharide–Silica Fluorescent Polymer Carrier for Selective Sensing and Glioblastoma Multiforme Therapy
inferred← citeshttps://doi.org/10.1016/j.fitote.2024.106113openalex-snapshot
Progress based on a multi-omics research strategy in the biosynthesis and modernization of active ingredients of Herpetospermum pedunculosum seeds
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2023.123173openalex-snapshot
New insights into the bioactive polysaccharides, proteins, and triterpenoids isolated from bitter melon (Momordica charantia) and their relevance for nutraceutical and food application: A review
inferred← citeshttps://doi.org/10.1016/j.jff.2022.104968openalex-snapshot
Momordica charantia-derived extracellular vesicles-like nanovesicles inhibited glioma proliferation, migration, and invasion by regulating the PI3K/AKT signaling pathway
inferred← citeshttps://doi.org/10.1016/j.phytol.2026.104144openalex-snapshot
Multi-target mechanism of bitter melon vine triterpenoids against lung cancer: A network pharmacology and experimental validation study
inferred← citeshttps://doi.org/10.1016/j.sajb.2024.05.030openalex-snapshot
Host-specific endophytes of Momordica charantia: A promising source for affordable lung cancer therapeutics
inferred← citeshttps://doi.org/10.1016/j.tice.2025.102897openalex-snapshot
Anticancer activity of Momordica charantia-derived extracellular vesicle-like particle against cervical cancer
inferred← citeshttps://doi.org/10.1158/1535-7163.mct-23-0718openalex-snapshot
Momordicine-I Suppresses Head and Neck Cancer Growth by Reprogrammimg Immunosuppressive Effect of the Tumor-Infiltrating Macrophages and B Lymphocytes
inferred← citeshttps://doi.org/10.1186/s12870-024-05688-zopenalex-snapshot
Enhancing the medicinal properties and phytochemical content of bitter melon (Momordica charantia L.) through elicitation with brassinosteroid, ethrel, and carrageenan
inferred← citeshttps://doi.org/10.1186/s12964-024-01951-wopenalex-snapshot
Momordicine-I suppresses head and neck cancer growth by modulating key metabolic pathways
inferred← citeshttps://doi.org/10.13005/bpj/2767openalex-snapshot
Emerging Potential of Momordica’s Bioactive Phytochemicals in Cancer Prevention and Therapy
inferred← citeshttps://doi.org/10.1631/jzus.b2500142openalex-snapshot
Momordicine I induces ER stress and inhibits OSCC by targeting ribosomal proteins
inferred← citeshttps://doi.org/10.18311/jnr/2026/54587openalex-snapshot
Unlocking the Therapeutic Potential of Momordica charantia Linn.: From Traditional Use to Modern Drug Discovery
inferred← citeshttps://doi.org/10.3390/cancers17142342openalex-snapshot
Targeting Triple-Negative Breast Cancer with Momordicine-I for Therapeutic Gain in Preclinical Models
inferred← citeshttps://doi.org/10.3390/cells15010044openalex-snapshot
Understanding the Tumor Microenvironment and Therapy Resistance in Head and Neck Squamous Cell Carcinoma
inferred← citeshttps://doi.org/10.3390/cimb47060425openalex-snapshot
Nutraceutical Potential of Bitter Melon (Momordica charantia) on Cancer Treatment: An Overview of In Vitro and Animal Studies
inferred← citeshttps://doi.org/10.3390/foods11050729openalex-snapshot
Microwave- and Ultrasound-Assisted Extraction of Cucurbitane-Type Triterpenoids from Momordica charantia L. Cultivars and Their Antiproliferative Effect on SAS Human Oral Cancer Cells
inferred← citeshttps://doi.org/10.3390/ijms24108918openalex-snapshot
The Role of Bitter Melon in Breast and Gynecological Cancer Prevention and Therapy
inferred← citeshttps://doi.org/10.3390/ijms251910518openalex-snapshot
Therapeutic Potential of Momordicine I from Momordica charantia: Cardiovascular Benefits and Mechanisms
inferred← citeshttps://doi.org/10.3390/pharmaceutics17030306openalex-snapshot
Anti-Tumor Strategies of Photothermal Therapy Combined with Other Therapies Using Nanoplatforms
inferred← citeshttps://doi.org/10.3390/vaccines13090940openalex-snapshot
Online Conference “Chronic Viral Infections and Cancer, Openings for Vaccines and Cure” VIRCAN2024, Monitoring the Progress
inferred← citeshttps://doi.org/10.4103/jpdtsm.jpdtsm_34_26openalex-snapshot
Network Pharmacology-integrated Molecular Modeling Analysis of Momordica Charantia Fruit Neuroprotective Phytocompounds against Parkinson’s Disease
inferred← citeshttps://doi.org/10.4196/kjpp.2023.27.1.75openalex-snapshot
Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ
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