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Growing Human Hepatocellular Tumors Undergo a Global Metabolic Reprogramming

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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MULTIVARIABLE PROGNOSTIC MODELS: ISSUES IN DEVELOPING MODELS, EVALUATING ASSUMPTIONS AND ADEQUACY, AND MEASURING AND REDUCING ERRORS
inferredcites →https://doi.org/10.1002/hep.20933openalex-snapshot
Management of Hepatocellular Carcinoma *
inferredcites →https://doi.org/10.1002/hep.26130openalex-snapshot
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Global epidemiology of nonalcoholic fatty liver disease—Meta‐analytic assessment of prevalence, incidence, and outcomes
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The role of metabolites and metabolomics in clinically applicable biomarkers of disease
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Quantitation of Plasma Circulating DNA Using Quantitative PCR for the Detection of Hepatocellular Carcinoma
inferredcites →https://doi.org/10.1016/j.ccell.2016.07.004openalex-snapshot
Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming
inferredcites →https://doi.org/10.1016/j.cell.2017.05.046openalex-snapshot
Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma
inferredcites →https://doi.org/10.1016/j.cell.2019.08.052openalex-snapshot
Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma
inferredcites →https://doi.org/10.1016/j.jhep.2016.05.035openalex-snapshot
Genetic profiling of hepatocellular carcinoma using next-generation sequencing
inferredcites →https://doi.org/10.1016/j.jhep.2018.08.027openalex-snapshot
Development of pre and post-operative models to predict early recurrence of hepatocellular carcinoma after surgical resection
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Recent and potential developments of biofluid analyses in metabolomics
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The application of proteomics in different aspects of hepatocellular carcinoma research
inferredcites →https://doi.org/10.1016/j.jprot.2016.09.008openalex-snapshot
Reveal the molecular signatures of hepatocellular carcinoma with different sizes by iTRAQ based quantitative proteomics
inferredcites →https://doi.org/10.1016/s0140-6736(03)14964-1openalex-snapshot
Hepatocellular carcinoma
inferredcites →https://doi.org/10.1016/s0140-6736(11)61347-0openalex-snapshot
Hepatocellular carcinoma
inferredcites →https://doi.org/10.1016/s1470-2045(12)70271-1openalex-snapshot
Biomarkers for early diagnosis of hepatocellular carcinoma
inferredcites →https://doi.org/10.1016/s1590-8658(10)60509-9openalex-snapshot
Surveillance and early diagnosis of hepatocellular carcinoma
inferredcites →https://doi.org/10.1021/ac048630xopenalex-snapshot
Statistical Total Correlation Spectroscopy: An Exploratory Approach for Latent Biomarker Identification from Metabolic 1 H NMR Data Sets
inferredcites →https://doi.org/10.1021/pr070063hopenalex-snapshot
Metabonomic Studies of Human Hepatocellular Carcinoma Using High-Resolution Magic-Angle Spinning 1H NMR Spectroscopy in Conjunction with Multivariate Data Analysis
inferredcites →https://doi.org/10.1038/nprot.2007.376openalex-snapshot
Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts
inferredcites →https://doi.org/10.1038/nrc1934openalex-snapshot
Hepatocellular carcinoma pathogenesis: from genes to environment
inferredcites →https://doi.org/10.1038/nrm.2016.25openalex-snapshot
Metabolomics: beyond biomarkers and towards mechanisms
inferredcites →https://doi.org/10.1038/s41575-019-0145-7openalex-snapshot
From NASH to HCC: current concepts and future challenges
inferredcites →https://doi.org/10.1038/s41598-019-42937-wopenalex-snapshot
Serum Concentrations of Citrate, Tyrosine, 2- and 3- Hydroxybutyrate are Associated with Increased 3-Month Mortality in Acute Heart Failure Patients
inferredcites →https://doi.org/10.1038/srep18175openalex-snapshot
Serum Metabolomics to Identify the Liver Disease-Specific Biomarkers for the Progression of Hepatitis to Hepatocellular Carcinoma
inferredcites →https://doi.org/10.1053/j.gastro.2018.01.064openalex-snapshot
Surveillance Imaging and Alpha Fetoprotein for Early Detection of Hepatocellular Carcinoma in Patients With Cirrhosis: A Meta-analysis
inferredcites →https://doi.org/10.1053/j.gastro.2018.08.065openalex-snapshot
Epidemiology and Management of Hepatocellular Carcinoma
inferredcites →https://doi.org/10.1055/s-2007-1007122openalex-snapshot
Prognosis of Hepatocellular Carcinoma: The BCLC Staging Classification
inferredcites →https://doi.org/10.1073/pnas.1710366114openalex-snapshot
Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC
inferredcites →https://doi.org/10.1080/15548627.2017.1313945openalex-snapshot
Protein kinase activity of the glycolytic enzyme PGK1 regulates autophagy to promote tumorigenesis
inferredcites →https://doi.org/10.1093/nar/gky310openalex-snapshot
MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis
inferredcites →https://doi.org/10.1097/ede.0b013e3181c30fb2openalex-snapshot
Assessing the Performance of Prediction Models
inferredcites →https://doi.org/10.1097/sla.0000000000000747openalex-snapshot
Prognostic Nomograms for Prediction of Recurrence and Survival After Curative Liver Resection for Hepatocellular Carcinoma
inferredcites →https://doi.org/10.1111/j.1572-0241.2006.00467.xopenalex-snapshot
Accuracy of Ultrasonography, Spiral CT, Magnetic Resonance, and Alpha-Fetoprotein in Diagnosing Hepatocellular Carcinoma: A Systematic Review. CME
inferredcites →https://doi.org/10.1111/jgh.13843openalex-snapshot
Significance of presence of microvascular invasion in specimens obtained after surgical treatment of hepatocellular carcinoma
inferredcites →https://doi.org/10.1126/science.aan4665openalex-snapshot
Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity
inferredcites →https://doi.org/10.1126/science.aaw5473openalex-snapshot
Metabolic reprogramming and cancer progression
inferredcites →https://doi.org/10.1158/0008-5472.can-12-3797openalex-snapshot
Proteomic and Lipidomic Signatures of Lipid Metabolism in NASH-Associated Hepatocellular Carcinoma
inferredcites →https://doi.org/10.1186/1471-2288-13-33openalex-snapshot
External validation of a Cox prognostic model: principles and methods
inferredcites →https://doi.org/10.1245/s10434-010-1038-8openalex-snapshot
Enhanced Detection of Early Hepatocellular Carcinoma by Serum SELDI-TOF Proteomic Signature Combined with Alpha-Fetoprotein Marker
inferredcites →https://doi.org/10.1371/journal.pone.0118658openalex-snapshot
The Singapore Liver Cancer Recurrence (SLICER) Score for Relapse Prediction in Patients with Surgically Resected Hepatocellular Carcinoma
inferredcites →https://doi.org/10.1371/journal.pone.0128058openalex-snapshot
Correction: The Singapore Liver Cancer Recurrence (SLICER) Score for Relapse Prediction in Patients with Surgically Resected Hepatocellular Carcinoma
inferredcites →https://doi.org/10.1371/journal.pone.0129000openalex-snapshot
Establishment and Validation of SSCLIP Scoring System to Estimate Survival in Hepatocellular Carcinoma Patients Who Received Curative Liver Resection
inferredcites →https://doi.org/10.1371/journal.pone.0155588openalex-snapshot
Solitary Large Hepatocellular Carcinoma: Staging and Treatment Strategy
inferredcites →https://doi.org/10.1371/journal.pone.0192748openalex-snapshot
Identification of race-associated metabolite biomarkers for hepatocellular carcinoma in patients with liver cirrhosis and hepatitis C virus infection
inferredcites →https://doi.org/10.14218/jcth.2013.00022openalex-snapshot
Proteome Analyses of Hepatocellular Carcinoma
inferredcites →https://doi.org/10.18632/oncotarget.13929openalex-snapshot
Serum and tissue markers in hepatocellular carcinoma and cholangiocarcinoma: clinical and prognostic implications
inferredcites →https://doi.org/10.3322/caac.21388openalex-snapshot
The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population‐based to a more “personalized” approach to cancer staging
inferredcites →https://doi.org/10.3390/biom11020235openalex-snapshot
Tissue-Specific Landscape of Metabolic Dysregulation during Ageing
inferredcites →https://doi.org/10.3390/cancers10110447openalex-snapshot
Lipid Metabolic Reprogramming in Hepatocellular Carcinoma
inferredcites →https://doi.org/10.3390/cells8040319openalex-snapshot
Apolipoprotein A-IV: A Multifunctional Protein Involved in Protection against Atherosclerosis and Diabetes
inferredcites →https://doi.org/10.3390/ijms151121229openalex-snapshot
From Plasminogen to Plasmin: Role of Plasminogen Receptors in Human Cancer
inferredcites →https://doi.org/10.3390/ijms20215498openalex-snapshot
Circulating-Free DNA Analysis in Hepatocellular Carcinoma: A Promising Strategy to Improve Patients’ Management and Therapy Outcomes
inferredcites →https://doi.org/10.3978/j.issn.2304-3865.2013.07.05openalex-snapshot
A review of hepatocellular carcinoma (HCC) staging systems.
inferredcites →https://doi.org/10.7326/0003-4819-87-5-642_1openalex-snapshot
Hepatocellular Carcinoma.
inferredcites →https://doi.org/10.7497/j.issn.2095-3941.2014.01.001openalex-snapshot
Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1007/16833_2022_96openalex-snapshot
Liver Cancer: Interdisciplinary Approach
inferred← citeshttps://doi.org/10.1007/s12672-024-01060-7openalex-snapshot
Nomograms incorporating hsa_circ_0029325 highly expressed in exosomes of hepatocellular carcinoma predict the postoperative outcomes
inferred← citeshttps://doi.org/10.1016/j.bioorg.2022.106229openalex-snapshot
Integrated transcriptomics and metabolomics analyses to investigate the anticancer mechanisms of cinobufagin against liver cancer through interfering with lipid, amino acid, carbohydrate, and nucleotide metabolism
inferred← citeshttps://doi.org/10.1016/j.clinre.2026.102814openalex-snapshot
Targeting metabolic dysregulation in HCC: Development and validation of a dual-biomarker diagnostic model integrating ADH1C and BHMT
inferred← citeshttps://doi.org/10.1016/j.coph.2022.102232openalex-snapshot
Dysregulation of immune checkpoint proteins in hepatocellular carcinoma: Impact on metabolic reprogramming
inferred← citeshttps://doi.org/10.1016/j.mad.2024.111996openalex-snapshot
Sirtuin 3 drives sex-specific responses to age-related changes in mouse embryonic fibroblasts
inferred← citeshttps://doi.org/10.1016/j.phymed.2021.153781openalex-snapshot
Compound Kushen Injection intervenes metabolic reprogramming and epithelial-mesenchymal transition of HCC via regulating β-catenin/c-Myc signaling
inferred← citeshttps://doi.org/10.1016/j.pneurobio.2022.102400openalex-snapshot
Brain Regions Show Different Metabolic and Protein Arginine Methylation Phenotypes in Frontotemporal Dementias and Alzheimer's Disease
inferred← citeshttps://doi.org/10.1093/gerona/glae221openalex-snapshot
Senolytics Enhance the Longevity of Caenorhabditis elegans by Altering Betaine Metabolism
inferred← citeshttps://doi.org/10.1101/2022.06.27.495427openalex-snapshot
Acinar-to-ductal metaplasia in the pancreas requires a glycolytic switch and functional mitochondria
inferred← citeshttps://doi.org/10.1101/2023.12.19.572398openalex-snapshot
Senolytics enhance longevity in Caenorhabditis elegans by altering betaine metabolism
inferred← citeshttps://doi.org/10.1111/jog.15834openalex-snapshot
Data‐independent acquisition for proteomic applications in early ‐ stage endometrial cancer progression
inferred← citeshttps://doi.org/10.1155/2022/7840606openalex-snapshot
Circulating Metabolic Markers Related to the Diagnosis of Hepatocellular Carcinoma
inferred← citeshttps://doi.org/10.1158/0008-5472.can-23-2213openalex-snapshot
Metabolic Reprogramming Is an Initial Step in Pancreatic Carcinogenesis That Can Be Targeted to Inhibit Acinar-to-Ductal Metaplasia
inferred← citeshttps://doi.org/10.21203/rs.3.rs-6932632/v1openalex-snapshot
Analysis of metabolite characteristics and signaling pathways in head and neck cancer based on metabolomics
inferred← citeshttps://doi.org/10.3389/fmed.2021.754709openalex-snapshot
Advances in Multi-Omics Applications in HBV-Associated Hepatocellular Carcinoma
inferred← citeshttps://doi.org/10.3390/metabo12040287openalex-snapshot
Metabolic Regulation of Hepatitis B Virus Infection in HBV-Transgenic Mice
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