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The Gut Microbiome and Cancer Immunotherapy: Can We Use the Gut Microbiome as a Predictive Biomarker for Clinical Response in Cancer Immunotherapy?
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/cam4.3694openalex-snapshot
Modulatory effects of gut microbiome in cancer immunotherapy: A novel paradigm for blockade of immune checkpoint inhibitors
inferredcites →https://doi.org/10.1002/ijc.31836openalex-snapshot
The bidirectional interaction of the gut microbiome and the innate immune system: Implications for chemotherapy‐induced gastrointestinal toxicity
inferredcites →https://doi.org/10.1002/onco.13812openalex-snapshot
The Impact of Adverse Events on Health Care Resource Utilization, Costs, and Mortality Among Patients Treated with Immune Checkpoint Inhibitors
inferredcites →https://doi.org/10.1007/s00335-021-09867-3openalex-snapshot
A review on the role of gut microbiota in immune checkpoint blockade therapy for cancer
inferredcites →https://doi.org/10.1007/s10620-020-06119-3openalex-snapshot
Relationship Between the Gut Microbiome and Systemic Chemotherapy
inferredcites →https://doi.org/10.1007/s11894-017-0540-6openalex-snapshot
Gastrointestinal and Hepatic Complications of Immune Checkpoint Inhibitors
inferredcites →https://doi.org/10.1007/s40121-020-00356-9openalex-snapshot
Fecal Microbiota Transplantation May Be the Best Option in Treating Multiple Clostridioides difficile Infection: A Network Meta-Analysis
inferredcites →https://doi.org/10.1016/j.eclinm.2020.100642openalex-snapshot
Faecal microbiota transplantation for recurrent Clostridioides difficile infection: An updated systematic review and meta-analysis
inferredcites →https://doi.org/10.1016/j.jtho.2019.04.007openalex-snapshot
The Diversity of Gut Microbiome is Associated With Favorable Responses to Anti–Programmed Death 1 Immunotherapy in Chinese Patients With NSCLC
inferredcites →https://doi.org/10.1016/j.neo.2017.08.004openalex-snapshot
Metagenomic Shotgun Sequencing and Unbiased Metabolomic Profiling Identify Specific Human Gut Microbiota and Metabolites Associated with Immune Checkpoint Therapy Efficacy in Melanoma Patients
inferredcites →https://doi.org/10.1016/s1470-2045(21)00353-3openalex-snapshot
CAR T-cell therapy for solid tumours
inferredcites →https://doi.org/10.1016/s2352-3026(21)00097-1openalex-snapshot
Surviving the storm: critical care outcomes of chimeric antigen receptor T-cell therapy
inferredcites →https://doi.org/10.1038/ncomms10391openalex-snapshot
Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis
inferredcites →https://doi.org/10.1038/s41746-020-0277-8openalex-snapshot
Translating evidence into practice: eligibility criteria fail to eliminate clinically significant differences between real-world and study populations
inferredcites →https://doi.org/10.1038/s42003-021-01741-xopenalex-snapshot
Gut microbiome diversity is an independent predictor of survival in cervical cancer patients receiving chemoradiation
inferredcites →https://doi.org/10.1038/srep30751openalex-snapshot
The Microbiome of Aseptically Collected Human Breast Tissue in Benign and Malignant Disease
inferredcites →https://doi.org/10.1053/j.seminhematol.2020.05.002openalex-snapshot
Uncovering the role of the gut microbiota in immune checkpoint blockade therapy: A mini-review
inferredcites →https://doi.org/10.1056/nejmoa1709684openalex-snapshot
Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma
inferredcites →https://doi.org/10.1093/annonc/mdx108openalex-snapshot
Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab
inferredcites →https://doi.org/10.1097/md.0000000000017348openalex-snapshot
Immune-related adverse events in cancer patients treated with immune checkpoint inhibitors
inferredcites →https://doi.org/10.1097/md.0000000000021788openalex-snapshot
Characterization of gut microbiota in patients with primary hepatocellular carcinoma received immune checkpoint inhibitors: A Chinese population-based study [RETRACTED]
inferredcites →https://doi.org/10.1111/j.1365-2753.2010.01516.xopenalex-snapshot
Assessment of study quality for systematic reviews: a comparison of the Cochrane Collaboration Risk of Bias Tool and the Effective Public Health Practice Project Quality Assessment Tool: methodological research
inferredcites →https://doi.org/10.1126/science.aan3706openalex-snapshot
Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors
inferredcites →https://doi.org/10.1126/science.aan4236openalex-snapshot
Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients
inferredcites →https://doi.org/10.1126/science.aao3290openalex-snapshot
The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients
inferredcites →https://doi.org/10.1126/science.abb5920openalex-snapshot
Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients
inferredcites →https://doi.org/10.1126/science.abf3363openalex-snapshot
Fecal microbiota transplant overcomes resistance to anti–PD-1 therapy in melanoma patients
inferredcites →https://doi.org/10.1126/scitranslmed.3005930openalex-snapshot
CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia
inferredcites →https://doi.org/10.1136/gutjnl-2019-320260openalex-snapshot
Australian consensus statements for the regulation, production and use of faecal microbiota transplantation in clinical practice
inferredcites →https://doi.org/10.1186/1748-5908-7-110openalex-snapshot
Managing symptoms during cancer treatments: evaluating the implementation of evidence-informed remote support protocols
inferredcites →https://doi.org/10.1186/s13046-019-1266-0openalex-snapshot
Advances in cancer immunotherapy 2019 – latest trends
inferredcites →https://doi.org/10.1186/s13073-019-0672-4openalex-snapshot
Relating the gut metagenome and metatranscriptome to immunotherapy responses in melanoma patients
inferredcites →https://doi.org/10.1186/s40425-019-0650-9openalex-snapshot
Gut microbiome affects the response to anti-PD-1 immunotherapy in patients with hepatocellular carcinoma
inferredcites →https://doi.org/10.1200/jco.2015.60.8448openalex-snapshot
Immune-Related Adverse Events, Need for Systemic Immunosuppression, and Effects on Survival and Time to Treatment Failure in Patients With Melanoma Treated With Ipilimumab at Memorial Sloan Kettering Cancer Center
inferredcites →https://doi.org/10.21037/jgo.2018.04.07openalex-snapshot
The gut microbiome and colorectal cancer: a review of bacterial pathogenesis
inferredcites →https://doi.org/10.3389/fimmu.2019.02989openalex-snapshot
Gut Microbiome as a Potential Factor for Modulating Resistance to Cancer Immunotherapy
inferredcites →https://doi.org/10.3389/fonc.2021.642110openalex-snapshot
Relating Gut Microbiome and Its Modulating Factors to Immunotherapy in Solid Tumors: A Systematic Review
inferredcites →https://doi.org/10.3390/cancers11010038openalex-snapshot
Gut Microbiota and Cancer: From Pathogenesis to Therapy
inferredcites →https://doi.org/10.3390/cancers13102353openalex-snapshot
The Gut Microbiome and Gastrointestinal Toxicities in Pelvic Radiation Therapy: A Clinical Review
inferredcites →https://doi.org/10.3390/ijms20061283openalex-snapshot
Killing Mechanisms of Chimeric Antigen Receptor (CAR) T Cells
inferredcites →https://doi.org/10.3390/ijms20174145openalex-snapshot
The Clinical Link between Human Intestinal Microbiota and Systemic Cancer Therapy
inferredcites →https://doi.org/10.3390/nu11071613openalex-snapshot
Gut Microbiome: Profound Implications for Diet and Disease
inferredcites →https://doi.org/10.3892/ol.2019.10841openalex-snapshot
Characteristics of fecal gut microbiota in patients with colorectal cancer at different stages and different sites
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Dysbiosis of Fecal Microbiota in Chinese Advanced Non-Small-Cell Lung Cancer Patients and its Role in Response to Immunotherapy
inferred← citeshttps://doi.org/10.1002/cam4.72061openalex-snapshot
Harnessing Gut Microbiota to Enhance Immunotherapy in NSCLC : From Mechanisms to Translational Applications
inferred← citeshttps://doi.org/10.1002/cnr2.1752openalex-snapshot
Maternal obesity and resistance to breast cancer treatments among offspring: Link to gut dysbiosis
inferred← citeshttps://doi.org/10.1002/ctm2.1508openalex-snapshot
Microbiota: A key factor affecting and regulating the efficacy of immunotherapy
inferred← citeshttps://doi.org/10.1007/978-3-030-80962-1_286-1openalex-snapshot
Introduction on Personalized Immune-Oncology
inferred← citeshttps://doi.org/10.1007/978-3-031-51216-2_9openalex-snapshot
Targeted Therapies and Immunotherapy
inferred← citeshttps://doi.org/10.1007/978-3-032-00773-5_286openalex-snapshot
Introduction on Personalized Immune-Oncology
inferred← citeshttps://doi.org/10.1007/978-981-97-6948-3_1openalex-snapshot
The Microbiome and Cancer: Understanding the Role of Microorganisms in Tumor Development and Treatment
inferred← citeshttps://doi.org/10.1007/s00262-025-04118-9openalex-snapshot
Gut modulation to regulate NF-κB in colorectal and gastric cancer therapy and inflammation
inferred← citeshttps://doi.org/10.1007/s00520-024-08889-2openalex-snapshot
Immune checkpoint inhibitor-induced diarrhea and colitis: an overview
inferred← citeshttps://doi.org/10.1007/s11912-023-01492-4openalex-snapshot
Integrative Oncology Approaches to Supporting Immune Checkpoint Inhibitor Treatment of Solid Tumours
inferred← citeshttps://doi.org/10.1016/j.bpg.2026.102148openalex-snapshot
Microbiome-directed therapies in oncology: from animal models to clinical implementation
inferred← citeshttps://doi.org/10.1016/j.critrevonc.2024.104328openalex-snapshot
Gut and local microbiota in patients with cancer: increasing evidence and potential clinical applications
inferred← citeshttps://doi.org/10.1016/j.esmogo.2025.100248openalex-snapshot
Treatment options for advanced small bowel adenocarcinoma: a systematic review
inferred← citeshttps://doi.org/10.1016/j.smim.2024.101891openalex-snapshot
The role of glycans in health and disease: Regulators of the interaction between gut microbiota and host immune system
inferred← citeshttps://doi.org/10.1016/j.toxrep.2025.102033openalex-snapshot
Immune checkpoint inhibitors: From friend to foe
inferred← citeshttps://doi.org/10.1039/d4mo00016aopenalex-snapshot
Species-level identification of enterotype-specific microbial markers for colorectal cancer and adenoma
inferred← citeshttps://doi.org/10.1097/cm9.0000000000003687openalex-snapshot
Leveraging gut microbiota for enhanced immune checkpoint blockade in solid tumor therapy
inferred← citeshttps://doi.org/10.1111/1759-7714.15032openalex-snapshot
Assessing the role of colonic and other anatomical sites uptake by [18F] FDG ‐PET/ CT and immune‐inflammatory peripheral blood indexes in patients with advanced non‐small cell lung cancer treated with first‐line immune checkpoint inhibitors
inferred← citeshttps://doi.org/10.1111/crj.13762openalex-snapshot
Implications of intestinal microecology and immune function alterations for immunotherapy outcomes in advanced unresectable lung adenocarcinoma
inferred← citeshttps://doi.org/10.1111/imcb.12798openalex-snapshot
Integrating functional metagenomics to decipher microbiome–immune interactions
inferred← citeshttps://doi.org/10.1128/cmr.00332-25openalex-snapshot
The gut microbiome and colorectal cancer
inferred← citeshttps://doi.org/10.1158/2159-8290.cd-23-0436openalex-snapshot
Neoadjuvant Durvalumab Alone or Combined with Novel Immuno-Oncology Agents in Resectable Lung Cancer: The Phase II NeoCOAST Platform Trial
inferred← citeshttps://doi.org/10.1177/17588359221122714openalex-snapshot
The role of gut microbiome in immune modulation in metastatic renal cell carcinoma
inferred← citeshttps://doi.org/10.1186/s12967-023-04582-wopenalex-snapshot
Leveraging circulating microbiome signatures to predict tumor immune microenvironment and prognosis of patients with non-small cell lung cancer
inferred← citeshttps://doi.org/10.1186/s12967-025-06370-0openalex-snapshot
Prioritizing gut microbial SNPs linked to immunotherapy outcomes in NSCLC patients by integrative bioinformatics analysis
inferred← citeshttps://doi.org/10.1186/s43046-026-00376-5openalex-snapshot
Microbiome and cancer immunotherapy: a bibliometric analysis
inferred← citeshttps://doi.org/10.20517/2394-5079.2026.04openalex-snapshot
Hepatocellular carcinoma tumor immune microenvironment: heterogeneity and therapeutic strategies
inferred← citeshttps://doi.org/10.20892/j.issn.2095-3941.2023.0394openalex-snapshot
Bile acids, gut microbiota, and therapeutic insights in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.21037/jtd-24-1201openalex-snapshot
Gut microbiota and metabolites associated with immunotherapy efficacy in extensive-stage small cell lung cancer: a pilot study
inferred← citeshttps://doi.org/10.21147/j.issn.1000-9604.2023.03.05openalex-snapshot
Effect of microbiome group on immune checkpoint inhibitors in treatment of gastrointestinal tumors
inferred← citeshttps://doi.org/10.21873/cdp.10354openalex-snapshot
Prognostic Impact of the Administration of Antibiotics and Proton Pump Inhibitors in Immune Checkpoint Inhibitor Combination Therapy for Advanced Renal Cell Carcinoma
inferred← citeshttps://doi.org/10.3389/fcimb.2022.892401openalex-snapshot
Analysis of Gut Microbiota Signature and Microbe-Disease Progression Associations in Locally Advanced Non-Small Cell Lung Cancer Patients Treated With Concurrent Chemoradiotherapy
inferred← citeshttps://doi.org/10.3389/fcimb.2023.1083987openalex-snapshot
Global research on the crosstalk between intestinal microbiome and colorectal cancer: A visualization analysis
inferred← citeshttps://doi.org/10.3389/fcimb.2026.1767998openalex-snapshot
The role of gut microbiota in liver metastasis of small cell lung cancer: mechanisms and therapeutic implications
inferred← citeshttps://doi.org/10.3389/fgene.2024.1378900openalex-snapshot
Gut resistome of NSCLC patients treated with immunotherapy
inferred← citeshttps://doi.org/10.3389/fimmu.2022.1065004openalex-snapshot
The negative effect of antibiotics on RCC patients with immunotherapy: A systematic review and meta-analysis
inferred← citeshttps://doi.org/10.3389/fimmu.2022.952546openalex-snapshot
Global research trends on the links between gut microbiota and cancer immunotherapy: A bibliometric analysis (2012-2021)
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1206953openalex-snapshot
Peripheral blood CD3+HLADR+ cells and associated gut microbiome species predict response and overall survival to immune checkpoint blockade
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1570233openalex-snapshot
Therapeutic targeting of the host-microbiota-immune axis: implications for precision health
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1638942openalex-snapshot
Gut microbiota and metabolites: emerging prospects in the treatment of non-small cell lung cancer
inferred← citeshttps://doi.org/10.3389/fmed.2022.908752openalex-snapshot
Predictive Biomarkers of Severe Immune-Related Adverse Events With Immune Checkpoint Inhibitors: Prevention, Underlying Causes, Intensity, and Consequences
inferred← citeshttps://doi.org/10.3389/fonc.2023.1145128openalex-snapshot
Advances in efficacy prediction and monitoring of neoadjuvant immunotherapy for non-small cell lung cancer
inferred← citeshttps://doi.org/10.3389/fonc.2023.1247614openalex-snapshot
Potential predictive role of gut microbiota to immunotherapy in HCC patients: a brief review
inferred← citeshttps://doi.org/10.3389/frmbi.2022.1049688openalex-snapshot
Foods may modify responsiveness to cancer immune checkpoint blockers by altering both the gut microbiota and activation of estrogen receptors in immune cells
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Guillain-Barre in the long-term acute care hospital setting: Ventilation does not prolong stay
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Introductory Chapter: Introduction to New Insights and Recent Progress in Immune Checkpoint Inhibitors
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Additional file 1 of Leveraging circulating microbiome signatures to predict tumor immune microenvironment and prognosis of patients with non-small cell lung cancer
inferred← citeshttps://doi.org/10.6084/m9.figshare.26638281openalex-snapshot
Additional file 2 of Leveraging circulating microbiome signatures to predict tumor immune microenvironment and prognosis of patients with non-small cell lung cancer
inferred← citeshttps://doi.org/10.7759/cureus.32586openalex-snapshot
Fecal Microbiota Transplant in Immunotherapy-Resistant Melanoma: What Can We Expect in the Near Future?
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