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Insulin-Like Growth Factor (IGF) System in Liver Diseases

https://doi.org/10.3390/ijms19051308

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Methylation of serum insulin‐like growth factor‐binding protein 7 promoter in hepatitis B virus‐associated hepatocellular carcinoma

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Characterization of the IGF axis components in isolated rat hepatic stellate cells

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Insulin-like growth factor-I reverts testicular atrophy in rats with advanced cirrhosis

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IGFBP7 downregulation is associated with tumor progression and clinical outcome in hepatocellular carcinoma

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MicroRNA‐190b regulates lipid metabolism and insulin sensitivity by targeting IGF‐1 and ADAMTS9 in non‐alcoholic fatty liver disease

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Human insulin-related DNA sequences map to chromosomes 2 and 11

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Normal levels of serum IGF-I: determinants and validity of current reference ranges

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IL-6 and IGF-1 are Independent Prognostic Factors of Liver Steatosis and Non-Alcoholic Steatohepatitis in Morbidly Obese Patients

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GH-independent IGF-I action is essential to prevent the development of nonalcoholic steatohepatitis in a GH-deficient rat model

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An evaluation of the role of insulin-like growth factors (IGF) and of type-I IGF receptor signalling in hepatocarcinogenesis and in the resistance of hepatocarcinoma cells against drug-induced apoptosis

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Blockade of IGF-1 receptor tyrosine kinase has antineoplastic effects in hepatocellular carcinoma cells

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EGCG inhibits activation of the insulin-like growth factor (IGF)/IGF-1 receptor axis in human hepatocellular carcinoma cells

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Insulin-like growth factor 2 gene methylation in peripheral blood mononuclear cells of patients with hepatitis C related cirrhosis or hepatocellular carcinoma

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The Insulin-Like Growth Factor System in Cancer

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The Circulating IGF System in Hepatocellular Carcinoma: The Impact of Liver Status and Treatment

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Factors correlated with serum insulin-like growth factor-I levels in health check-up subjects

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IGF activation in a molecular subclass of hepatocellular carcinoma and pre-clinical efficacy of IGF-1R blockage

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Insulin-Like Growth Factor-I and -II Levels Are Associated with the Progression of Nonalcoholic Fatty Liver Disease in Obese Children

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The Role of Insulin-Like Growth Factor-1 on Steatohepatitis

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Insulin-like growth factor (IGF) axis in cancerogenesis

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Histopathological aspects of liver under variable food restriction: Has the intense one-week food restriction a protective effect on non-alcoholic-fatty-liver-disease (NAFLD) development?

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IGF-dependent and IGF-independent actions of IGF-binding protein-1 and -2: implications for metabolic homeostasis

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Evidence of autocrine regulation in human hepatoma cell lines

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Molecular Regulation of Insulin-like Growth Factor-I and Its Principal Binding Protein, IGFBP-3

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Regulation of the growth hormone receptor/binding protein, insulin-like growth factor ternary complex system in human cirrhosis

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Low doses of insulin-like growth factor-I improve nitrogen retention and food efficiency in rats with early cirrhosis

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Osteopenia in rats with liver cirrhosis: beneficial effects of IGF-I treatment

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Insulin-like growth factor II (IGF-II) secreted from HepG2 human hepatocellular carcinoma cells shows angiogenic activity

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Antifibrogenic effect in vivo of low doses of insulin-like growth factor-I in cirrhotic rats

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Regulatory Actions of Insulin-like Growth Factor-binding Proteins

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Role of the liver in the control of carbohydrate and lipid homeostasis

inferredcites →https://doi.org/10.1016/s1665-2681(19)31009-9openalex-snapshot

IGF-I and IGFBP-3 serum levels in patients hospitalized for complications of liver cirrhosis

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The expression of insulin-like growth factor binding proteins in human hepatocellular carcinoma

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The Association Between IGF-1 Levels and the Histologic Severity of Nonalcoholic Fatty Liver Disease

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Analysis of the IGF Axis in Preneoplastic Hepatic Foci and Hepatocellular Neoplasms Developing after Low-Number Pancreatic Islet Transplantation into the Livers of Streptozotocin Diabetic Rats

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Focal overexpression of insulin-like growth factor 2 by hepatocytes and cholangiocytes in viral liver cirrhosis

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Liver transduction with a simian virus 40 vector encoding insulin-like growth factor I reduces hepatic damage and the development of liver cirrhosis

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Phosphorylated IGFBP-1 as a non-invasive predictor of liver fat in NAFLD

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IGF-I induces senescence of hepatic stellate cells and limits fibrosis in a p53-dependent manner

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Increased IGF‐I : IGFBP‐3 ratio in patients with hepatocellular carcinoma

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Impaired intestinal sugar transport in cirrhotic rats: Correction by low doses of insulin-like growth factor I

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Hepatoprotective effects of insulin-like growth factor I in rats with carbon tetrachloride-induced cirrhosis

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PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival

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Diethylnitrosamine induces long-lasting re-expression of insulin-like growth factor II during early stages of liver carcinogenesis in mice

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Reduced Growth Hormone Secretion is Associated with Nonalcoholic Fatty Liver Disease in Obese Children

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Serum insulin-like growth factor-II as a serologic marker of small hepatocellular carcinoma

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IGFBP-1 and IGF-I as markers for advanced fibrosis in NAFLD – a pilot study

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Prognostic significance of insulin-like growth factor-I serum levels in acute decompensation of cirrhosis

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Characterization of the insulin-like growth factor axis in a human hepatoma cell line (PLC)

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Serum Insulin-like Growth Factors and Insulin-like Growth Factor-binding Proteins: Clinical Implications

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Antisense Oligodeoxynucleotides of IGF-II Selectively Inhibit Growth of Human Hepatoma Cells Overproducing IGF-II

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Liver regeneration. 2. Role of growth factors and cytokines in hepatic regeneration.

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Hepatocyte proliferation during liver regeneration is impaired in mice with liver‐specific IGF‐1R knockout

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Serum concentrations of human insulin-like growth factor-1 and levels of insulin-like growth factor-binding protein-5 in patients with nonalcoholic fatty liver disease

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Insulin‐like growth factor binding protein‐related protein 1 contributes to hepatic fibrogenesis

inferredcites →https://doi.org/10.1111/apa.13685openalex-snapshot

Insulin‐like growth factor 1 and metabolic parameters are associated with nonalcoholic fatty liver disease in obese children and adolescents

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The risk of osteoporosis in patients with liver cirrhosis: a meta‐analysis of literature studies

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Lower levels of insulin‐like growth factor‐1 standard deviation score are associated with histological severity of non‐alcoholic fatty liver disease

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Systematic review: the epidemiology and natural history of non‐alcoholic fatty liver disease and non‐alcoholic steatohepatitis in adults

inferredcites →https://doi.org/10.1111/j.1365-2265.2009.03707.xopenalex-snapshot

Ascites from patients with alcoholic liver cirrhosis contains higher IGF‐I bioactivity than serum

inferredcites →https://doi.org/10.1111/j.1365-2265.2011.04291.xopenalex-snapshot

Nonalcoholic fatty liver disease is associated with increased GHBP and reduced GH/IGF‐I levels

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Insulin‐like growth factors I and II

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Insulin-like growth factor-I and the liver

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Single nucleotide polymorphisms associated with metastatic tumour antigen 1 overexpression in patients with hepatocellular carcinoma

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Relationship between serum circulating insulin‐like growth factor‐1 and liver fat in the U nited S tates

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Future therapy for non‐alcoholic fatty liver disease

inferredcites →https://doi.org/10.1126/science.274.5291.1379openalex-snapshot

Liver Failure and Defective Hepatocyte Regeneration in Interleukin-6-Deficient Mice

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Insulin-like growth factor I improves intestinal barrier function in cirrhotic rats

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Mechanisms of Organ Injury and Repair by Macrophages

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Effect of insulin-like growth factor I on in vivo intestinal absorption of d -galactose in cirrhotic rats

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Relationship between GH/IGF-1 Axis, Graft Recovery, and Early Survival in Patients Undergoing Liver Transplantation

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Molecular Profiling of Human Hepatocellular Carcinoma Defines Mutually Exclusive Interferon Regulation and Insulin-Like Growth Factor II Overexpression

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Insulin-Like Growth Factor-1 Receptor Inhibition Induces a Resistance Mechanism via the Epidermal Growth Factor Receptor/HER3/AKT Signaling Pathway: Rational Basis for Cotargeting Insulin-Like Growth Factor-1 Receptor and Epidermal Growth Factor Receptor in Hepatocellular Carcinoma

inferredcites →https://doi.org/10.1158/1078-0432.ccr-10-2774openalex-snapshot

Insulin-like Growth Factor–Binding Protein-7 Functions as a Potential Tumor Suppressor in Hepatocellular Carcinoma

inferredcites →https://doi.org/10.1158/1078-0432.ccr-11-2853openalex-snapshot

Serum Insulin-Like Growth Factor-1 Levels Predict Outcomes of Patients with Advanced Hepatocellular Carcinoma Receiving Antiangiogenic Therapy

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Serum Insulin-like Growth Factor-I Level Is an Independent Predictor of Recurrence and Survival in Early Hepatocellular Carcinoma: A Prospective Cohort Study

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Insulin-Like Growth Factors and Insulin-Like Growth Factor Binding Proteins in Adult Patients with Severe Liver Disease before and after Orthotopic Liver Transplantation

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Pilot Study of Elevated Levels of Insulin-Like Growth Factor-Binding Protein-2 as Indicators of Hepatocellular Carcinoma

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Role of Insulin-Like Growth Factor Iin Maintaining Normal Glucose Homeostasis

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The relative roles of growth hormone and IGF-1 in controlling insulin sensitivity

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Upregulation of the Insulin Receptor and Type I Insulin-Like Growth Factor Receptor Are Early Events in Hepatocarcinogenesis

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Association of Elevated IGFBP-1 with Increased IGF-II Concentration in Patients with Carcinoma of the Liver

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Effect of intracellular lipid accumulation in a new model of non-alcoholic fatty liver disease

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Characterization of insulin-like-growth factor II (IGF II) mRNA positive hepatic altered foci and IGF II expression in hepatocellular carcinoma during diethylnitrosamine-induced hepatocarcinogenesis in rats.

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Expression levels of insulin-like growth factors and receptors in hepatocellular carcinoma: a retrospective study

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Human conditions of insulin-like growth factor-I (IGF-I) deficiency

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Clinical and Prognostic Implications of Plasma Insulin-Like Growth Factor-1 and Vascular Endothelial Growth Factor in Patients With Hepatocellular Carcinoma

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Insulin-Like Growth Factors I and II. Peptide, Messenger Ribonucleic Acid and Gene Structures, Serum, and Tissue Concentrations*

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The Insulin-Like Growth Factor-Binding Protein (IGFBP) Superfamily

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The Somatomedin Hypothesis: 2001

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Low Doses of Insulin-Like Growth Factor I Improve Insulin Resistance, Lipid Metabolism, and Oxidative Damage in Aging Rats

inferredcites →https://doi.org/10.1210/en.2011-1601openalex-snapshot

Prenatal Dexamethasone Exposure Potentiates Diet-Induced Hepatosteatosis and Decreases Plasma IGF-I in a Sex-Specific Fashion

inferredcites →https://doi.org/10.1210/endo.138.11.5540openalex-snapshot

Insulin-Like Growth Factors Stimulate Expression of Hepatocyte Growth Factor But Not Transforming Growth Factor β1 in Cultured Hepatic Stellate Cells*

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Editorial: Insulin-Like Growth Factor I Receptor Signaling—Overlapping or Redundant Pathways?

inferredcites →https://doi.org/10.1210/jc.2011-1227openalex-snapshot

Nonalcoholic Fatty Liver Disease Is Associated with Low Circulating Levels of Insulin-Like Growth Factor-I

inferredcites →https://doi.org/10.1210/jc.2012-3290openalex-snapshot

Insulin-Like Growth Factor-I, Inflammatory Proteins, and Fibrosis in Subjects With Nonalcoholic Fatty Liver Disease

inferredcites →https://doi.org/10.1245/s10434-009-0904-8openalex-snapshot

Relationship of Insulin-Like Growth Factors System Gene Polymorphisms with the Susceptibility and Pathological Development of Hepatocellular Carcinoma

inferredcites →https://doi.org/10.12659/aot.883819openalex-snapshot

Insulin-like growth factor I correlates with MELD and returns to normal level after liver transplantation

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The In Utero Programming Effect of Increased Maternal Androgens and a Direct Fetal Intervention on Liver and Metabolic Function in Adult Sheep

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Serum Insulin-Like Growth Factor-1 Predicts Disease Progression and Survival in Patients with Hepatocellular Carcinoma Who Undergo Transarterial Chemoembolization

inferredcites →https://doi.org/10.1371/journal.pone.0097136openalex-snapshot

HCC Development Is Associated to Peripheral Insulin Resistance in a Mouse Model of NASH

inferredcites →https://doi.org/10.1371/journal.pone.0170394openalex-snapshot

Validation of a Modified Child-Turcotte-Pugh Classification System Utilizing Insulin-Like Growth Factor-1 for Patients with Hepatocellular Carcinoma in an HBV Endemic Area

inferredcites →https://doi.org/10.1371/journal.pone.0189642openalex-snapshot

Diversification of the insulin-like growth factor 1 gene in mammals

inferredcites →https://doi.org/10.15017/1398601openalex-snapshot

Differential expression of insulin-like growth factor 1 in human primary liver cancer.

inferredcites →https://doi.org/10.1515/cclm.1996.34.5.401openalex-snapshot

Characterization of Insulin-Like Growth Factor (IGF)-I-Receptor Binding Sites during In Vitro Transformation of Rat Hepatic Stellate Cells to Myofibroblasts

inferredcites →https://doi.org/10.1530/eje-09-0374openalex-snapshot

Association between hepatic steatosis and serum IGF1 and IGFBP-3 levels in a population-based sample

inferredcites →https://doi.org/10.1530/eje.0.1400577openalex-snapshot

IGF-I production by adult rat hepatocytes is stimulated by transforming growth factor-alpha and transforming growth factor-beta1

inferredcites →https://doi.org/10.1530/erc-13-0231openalex-snapshot

IGF2 and cancer

inferredcites →https://doi.org/10.1677/jme.0.0210097openalex-snapshot

Insulin-like growth factor-binding proteins: functional diversity or redundancy?

inferredcites →https://doi.org/10.1677/joe.0.1720457openalex-snapshot

GH is a regulator of IGF2 promoter-specific transcription in human liver

inferredcites →https://doi.org/10.18632/oncotarget.19186openalex-snapshot

Serum insulin-like growth factor-1 and its binding protein 3 as prognostic factors for the incidence, progression, and outcome of hepatocellular carcinoma: a systematic review and meta-analysis

inferredcites →https://doi.org/10.18632/oncotarget.4176openalex-snapshot

Validation of an IGF-CTP scoring system for assessing hepatic reserve in egyptian patients with hepatocellular carcinoma

inferredcites →https://doi.org/10.20411/pai.v2i1.183openalex-snapshot

HIV/HCV Co-infection, Liver Disease Progression, and Age-Related IGF-1 Decline

inferredcites →https://doi.org/10.2169/internalmedicine.56.7626openalex-snapshot

The Relationship between the Growth Hormone/Insulin-like Growth Factor System and the Histological Features of Nonalcoholic Fatty Liver Disease

inferredcites →https://doi.org/10.3382/ps/pew043openalex-snapshot

Developmental changes of Insulin-like growth factors in the liver and muscle of chick embryos

inferredcites →https://doi.org/10.3389/fphys.2016.00147openalex-snapshot

Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation

inferredcites →https://doi.org/10.3390/ijms18071447openalex-snapshot

The Role of Growth Hormone and Insulin-Like Growth Factor-I in the Liver

inferredcites →https://doi.org/10.3748/wjg.14.5419openalex-snapshot

Liver insulin-like growth factor 2 methylation in hepatitis C virus cirrhosis and further occurrence of hepatocellular carcinoma

inferredcites →https://doi.org/10.3748/wjg.v10.i17.2529openalex-snapshot

Hematotesticular barrier is altered from early stages of liver cirrhosis: Effect of insulin-like growth factor 1

inferredcites →https://doi.org/10.3748/wjg.v10.i18.2740openalex-snapshot

Clinical significance of serum IGF-I, IGF-II and IGFBP-3 in liver cirrhosis

inferredcites →https://doi.org/10.3748/wjg.v11.i27.4272openalex-snapshot

Expression of albumin, IGF-1, IGFBP-3 in tumor tissues and adjacent non-tumor tissues of hepatocellular carcinoma patients with cirrhosis

inferredcites →https://doi.org/10.3748/wjg.v11.i30.4655openalex-snapshot

Expression and alteration of insulin-like growth factor II-messenger RNA in hepatoma tissues and peripheral blood of patients with hepatocellular carcinoma

inferredcites →https://doi.org/10.3748/wjg.v19.i22.3375openalex-snapshot

What about non-alcoholic fatty liver disease as a new criterion to define metabolic syndrome?

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Overexpression of insulin-like growth factor-I receptor as a pertinent biomarker for hepatocytes malignant transformation

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IGFBPrP1 induces liver fibrosis by inducing hepatic stellate cell activation and hepatocyte apoptosisviaSmad2/3 signaling

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Role of liver biopsy in nonalcoholic fatty liver disease.

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Insulin-like growth factor-1 mRNA isoforms and insulin-like growth factor-1 receptor mRNA expression in chronic hepatitis C

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IGF-1 promotes the growth and metastasis of hepatocellular carcinomaviathe inhibition of proteasome-mediated cathepsin B degradation

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Expression of IGF-II in early experimental hepatocellular carcinomas and its significance in early diagnosis

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[Expression and significance of insulin-like growth factor-1 and insulin-like growth factor binding protein-3 in hepatocyte steatosis model].

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Recent Insights into Insulin-Like Growth Factor Binding Protein 2 Transcriptional Regulation

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Prognostic significance of serum insulin-like growth factor-1 in patients with hepatocellular carcinoma following transarterial chemoembolization

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The insulin-like growth factor (IGF) signaling axis and hepatitis C virus-associated carcinogenesis (Review)

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Serum IGFBP-3 is a more effective predictor than IGF-1 and IGF-2 for the development of hepatocellular carcinoma in patients with chronic HCV infection

inferredcites →https://doi.org/10.3892/ol.2017.5934openalex-snapshot

Low expression levels of insulin-like growth factor binding protein-3 are correlated with poor prognosis for patients with hepatocellular carcinoma

inferredcites →https://doi.org/10.3892/or.2013.2546openalex-snapshot

The insulin-like growth factor-1 and expression of its binding protein-3 in chronic hepatitis C and hepatocellular carcinoma

inferredcites →https://doi.org/10.3892/or.2014.3505openalex-snapshot

IGF axis and other factors in HPV-related and HPV-unrelated carcinogenesis (Review)

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Circulating insulin-like growth factor-binding protein 3 as prognostic biomarker in liver cirrhosis

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Prognostic Significance of p53, mTOR, c-Met, IGF-1R, and HSP70 Overexpression after the Resection of Hepatocellular Carcinoma

inferredcites →https://doi.org/10.5114/wo.2012.29291openalex-snapshot

Alterations of insulin-like growth factor I (IGF-I) and estradiol serum levels in chronic hepatitis C

inferredcites →https://doi.org/10.5493/wjem.v6.i1.21openalex-snapshot

Hepatocellular carcinoma: Where are we?

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A Survey of Correlation Between Insulin-Like Growth Factor-I (IGF-I) Levels and Severity of Liver Cirrhosis

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Serum Insulinlike Growth Factor-1 and Its Binding Protein-3 Levels in Children With Cirrhosis Waiting for a Liver Transplant

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Predictive Value of Serum Insulin-like Growth Factor-1 in Hepatocellular Carcinoma

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Serum Insulin-Like Growth Factor-1 (IGF-1): a Novel Prognostic Factor for Early Recurrence of Hepatocellular Carcinoma (HCC)

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HMGA2 drives the IGFBP1 / AKT pathway to counteract the increase in P27KIP1 protein levels in mtDNA / RNA ‐less cancer cells

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Serum IGF ‐1 and the Risk of Cardio‐Kidney Outcomes in Metabolic Dysfunction‐Associated Steatotic Liver Disease

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Insulin‐like growth factor binding protein 1 ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease

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Effect of Benzo(a)pyrene on the Expression of miR-483-3p in Hepatocyte Primary Culture and Rat Liver

inferred← citeshttps://doi.org/10.1152/ajpgi.00184.2021openalex-snapshot

Myostatin in combination with creatine phosphokinase or albumin may differentiate patients with cirrhosis and sarcopenia

inferred← citeshttps://doi.org/10.1152/ajpregu.00128.2020openalex-snapshot

Liver circadian clock disruption alters perivascular adipose tissue gene expression and aortic function in mice

inferred← citeshttps://doi.org/10.1155/2019/4601484openalex-snapshot

A Unique Case of IGF-2 Induced Hypoglycemia Associated with Hepatocellular Carcinoma

inferred← citeshttps://doi.org/10.1155/2019/8742075openalex-snapshot

Evaluation of the Effect Derived from Silybin with Vitamin D and Vitamin E Administration on Clinical, Metabolic, Endothelial Dysfunction, Oxidative Stress Parameters, and Serological Worsening Markers in Nonalcoholic Fatty Liver Disease Patients

inferred← citeshttps://doi.org/10.1155/2022/6831779openalex-snapshot

Upregulated IGFBP3 with Aging Is Involved in Modulating Apoptosis, Oxidative Stress, and Fibrosis: A Target of Age‐Related Erectile Dysfunction

inferred← citeshttps://doi.org/10.1155/2023/2970429openalex-snapshot

Screening of Biomarkers in Liver Tissue after Bariatric Surgery Based on WGCNA and SVM-RFE Algorithms

inferred← citeshttps://doi.org/10.1155/anu/2689798openalex-snapshot

Water Added Probiotics Attenuates Sumithion‐Induced Toxicity on Growth, Intestinal Deformities, Erythrocytic Abnormalities, and Immunity in Nile Tilapia ( Oreochromis niloticus )

inferred← citeshttps://doi.org/10.1155/jai/5475569openalex-snapshot

Temperature‐Induced Expression Dynamics for the Stress, Appetite and Growth‐Related Genes in Nile Tilapia ( Oreochromis niloticus )

inferred← citeshttps://doi.org/10.1158/0008-5472.can-20-1281openalex-snapshot

Circulating Insulin-like Growth Factor-I Concentrations and Risk of 30 Cancers: Prospective Analyses in UK Biobank

inferred← citeshttps://doi.org/10.1158/0008-5472.can-20-2818openalex-snapshot

Combinatorial Normalization of Liver-Derived Cytokine Pathways Alleviates Hepatic Tumor-Associated Cachexia in Zebrafish

inferred← citeshttps://doi.org/10.1158/1940-6207.c.6547276.v1openalex-snapshot

Data from Adiposity, Adulthood Weight Change, and Risk of Incident Hepatocellular Carcinoma

inferred← citeshttps://doi.org/10.1158/1940-6207.capr-20-0549openalex-snapshot

Adiposity, Adulthood Weight Change, and Risk of Incident Hepatocellular Carcinoma

inferred← citeshttps://doi.org/10.1159/000535332openalex-snapshot

Immunohistochemical Expression of Insulin-Like Growth Factor-1 Receptor and Its Association with Clinicopathological Parameters in Hepatocellular Carcinoma

inferred← citeshttps://doi.org/10.1172/jci.insight.144863openalex-snapshot

IGF1R controls mechanosignaling in myofibroblasts required for pulmonary alveologenesis

inferred← citeshttps://doi.org/10.1172/jci.insight.160257openalex-snapshot

Time-restricted feeding reduces cardiovascular disease risk in obese mice

inferred← citeshttps://doi.org/10.1172/jci.insight.187099openalex-snapshot

Live-cell imaging of human liver fibrosis using hepatic micro-organoids

inferred← citeshttps://doi.org/10.1177/09603271241251451openalex-snapshot

Expression of PVT-1 and miR-29a/29b as reliable biomarkers for liver cirrhosis and their correlation with the inflammatory biomarkers profile.

inferred← citeshttps://doi.org/10.1177/2055116919856129openalex-snapshot

Non-islet-cell tumour hypoglycaemia in a cat with hepatocellular carcinoma

inferred← citeshttps://doi.org/10.1186/s10020-023-00752-0openalex-snapshot

IGF2 deficiency promotes liver aging through mitochondrial dysfunction and upregulated CEBPB signaling in d-galactose-induced aging mice

inferred← citeshttps://doi.org/10.1186/s12864-023-09740-4openalex-snapshot

Construction of a high-density genetic linkage map and QTL mapping of growth and cold tolerance traits in Takifugu fasciatus

inferred← citeshttps://doi.org/10.1186/s12879-019-4529-7openalex-snapshot

Mechanistic study of the cause of decreased blood 1,25-Dihydroxyvitamin D in sepsis

inferred← citeshttps://doi.org/10.1186/s12885-020-07135-2openalex-snapshot

Global targetome analysis reveals critical role of miR-29a in pancreatic stellate cell mediated regulation of PDAC tumor microenvironment

inferred← citeshttps://doi.org/10.1186/s12885-023-10561-7openalex-snapshot

IGF-1R down regulates the sensitivity of hepatocellular carcinoma to sorafenib through the PI3K / akt and RAS / raf / ERK signaling pathways

inferred← citeshttps://doi.org/10.1186/s12885-025-14491-4openalex-snapshot

Basal metabolic rate shapes the development and progression of hepatocellular carcinoma

inferred← citeshttps://doi.org/10.1186/s12935-020-01496-1openalex-snapshot

RETRACTED ARTICLE: Circular RNA circ_0000517 regulates hepatocellular carcinoma development via miR-326/IGF1R axis

inferred← citeshttps://doi.org/10.1186/s12935-023-02861-6openalex-snapshot

A review on the role of long non-coding RNA and microRNA network in clear cell renal cell carcinoma and its tumor microenvironment

inferred← citeshttps://doi.org/10.1186/s13287-023-03605-zopenalex-snapshot

Advancements in the pathogenesis of hepatic osteodystrophy and the potential therapeutic of mesenchymal stromal cells

inferred← citeshttps://doi.org/10.1186/s40360-023-00683-wopenalex-snapshot

Berberine-loaded albumin nanoparticles reverse aflatoxin B1-induced liver hyperplasia

inferred← citeshttps://doi.org/10.1186/s43066-023-00261-zopenalex-snapshot

Evaluation of handgrip strength as a predictor of sarcopenia in patients with HCV-related cirrhosis

inferred← citeshttps://doi.org/10.1186/s43141-021-00262-8openalex-snapshot

A novel model based on interleukin 6 and insulin-like growth factor II for detection of hepatocellular carcinoma associated with hepatitis C virus

inferred← citeshttps://doi.org/10.1186/s43141-022-00369-6openalex-snapshot

Efficient generation of functional pancreatic β cells from dental-derived stem cells via laminin-induced differentiation

inferred← citeshttps://doi.org/10.1210/clinem/dgad212openalex-snapshot

IGF-1 and Risk of Morbidity and Mortality From Cancer, Cardiovascular Diseases, and All Causes in EPIC-Heidelberg

inferred← citeshttps://doi.org/10.1242/dev.204226openalex-snapshot

Acute inflammation induces acute megakaryopoiesis with impaired platelet production during fetal hematopoiesis

inferred← citeshttps://doi.org/10.12677/acm.2022.1281130openalex-snapshot

Effects of Growth Factors and Cytokines on the Liver Regeneration Phase of DILI

inferred← citeshttps://doi.org/10.12677/acm.2023.1371634openalex-snapshot

Current Research Progress of Pathogenesis, Diagnosis and Treatment of Sarcopenia in Liver Cirrhosis

inferred← citeshttps://doi.org/10.12677/tcm.2021.104067openalex-snapshot

Integrating Network Pharmacology and Weighted Gene Co-Expression Network Analysis to Explore the Potential Targets and Mechanism of Linghe Granules in the Treatment of Metabolism Related Fatty Liver Disease

inferred← citeshttps://doi.org/10.12688/f1000research.124879.1openalex-snapshot

Quality assessment of systematic literature on uterine fibroids: a systematic review

inferred← citeshttps://doi.org/10.12688/f1000research.124879.2openalex-snapshot

Quality assessment of systematic literature on uterine fibroids: a systematic review

inferred← citeshttps://doi.org/10.1371/journal.pmed.1003149openalex-snapshot

Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts

inferred← citeshttps://doi.org/10.1371/journal.pone.0219412openalex-snapshot

Serum miR-379 expression is related to the development and progression of hypercholesterolemia in non-alcoholic fatty liver disease

inferred← citeshttps://doi.org/10.1371/journal.pone.0290384openalex-snapshot

Effect of autologous platelet-rich plasma on patients with acute type A aortic dissection underwent aortic arch replacement: A retrospective cohort study

inferred← citeshttps://doi.org/10.1371/journal.pone.0327668openalex-snapshot

Magnetic resonance evaluation of three-dimensional liver fat fraction by hepatitis C status and associations with inflammatory cytokines

inferred← citeshttps://doi.org/10.14202/vetworld.2024.1619-1628openalex-snapshot

Impact of ginger powder (Zingiber officinale) supplementation on the performance, biochemical parameters, antioxidant status, and rumen fermentation in Ossimi rams

inferred← citeshttps://doi.org/10.14218/ge.2022.00017openalex-snapshot

Effect of Fennel ( Foeniculum Vulgare ) Seed Powder Consumption on Insulin-like Growth Factor 1 Gene Expression in the Liver Tissue of Growing Lambs

inferred← citeshttps://doi.org/10.14218/jcth.2022.00392openalex-snapshot

IGF2-NR4A2 Signaling Regulates Macrophage Subtypes to Attenuate Liver Cirrhosis

inferred← citeshttps://doi.org/10.14309/ajg.0000000000002300openalex-snapshot

Growth Hormone Therapy in Decompensated Cirrhosis: An Open-Label, Randomized Control Trial

inferred← citeshttps://doi.org/10.14309/ctg.0000000000000829openalex-snapshot

Serum Insulin-Like Growth Factor 1 and the Prognosis of Patients With Advanced Liver Diseases: A Meta-Analysis

inferred← citeshttps://doi.org/10.14341/omet13124openalex-snapshot

Mineral disorders in patients with chronic liver disease. Part 1: epidemiology and pathophysiology

inferred← citeshttps://doi.org/10.14341/omet13306openalex-snapshot

Vitamin D and Bone Metabolism in Non-Alcoholic, Non-Viral Liver Cirrhosis: A Pilot Study

inferred← citeshttps://doi.org/10.14341/probl12791openalex-snapshot

Discordant parameters of insulin-like growth factor 1 and growth hormone in the diagnosis and monitoring of acromegaly

inferred← citeshttps://doi.org/10.14500/aro.12181openalex-snapshot

Investigating the Relationship Between Insulin-Like Growth Factor-I and Thyroid Hormones in Thyroid Disorder Patients

inferred← citeshttps://doi.org/10.14739/2310-1210.2022.4.255267openalex-snapshot

Possibilities for implementing of anti-fibrotic and anti-inflammatory effects of metabolic therapy in acute alcoholic disorders under experimental conditions

inferred← citeshttps://doi.org/10.1507/endocrj.ej23-0157openalex-snapshot

Association of nonalcoholic fatty liver disease and growth hormone deficiency: a systematic review and meta-analysis

inferred← citeshttps://doi.org/10.1530/ec-21-0175openalex-snapshot

Reference values for IGF-I serum concentration in an adult population: use of the VARIETE cohort for two new immunoassays

inferred← citeshttps://doi.org/10.18632/aging.204364openalex-snapshot

HBP1 inhibits the development of type 2 diabetes mellitus through transcriptional activation of the IGFBP1 gene

inferred← citeshttps://doi.org/10.1900/rds.2020.16.24openalex-snapshot

Insulin-like Growth Factor and its Therapeutic Potential for Diabetes Complications Mechanisms and Metabolic Links: A Review

inferred← citeshttps://doi.org/10.20945/2359-3997000000192openalex-snapshot

Laboratory investigations in the diagnosis and follow-up of GH-related disorders

inferred← citeshttps://doi.org/10.21037/atm-2020-ubih-06openalex-snapshot

Dairy consumption and hepatocellular carcinoma risk

inferred← citeshttps://doi.org/10.21037/tp-23-424openalex-snapshot

Long non-coding RNA growth arrest-specific 5 inhibits liver fibrogenesis in biliary atresia by interacting with microRNA-222 and repressing IGF1/AKT signaling

inferred← citeshttps://doi.org/10.21203/rs.3.rs-1216787/v1openalex-snapshot

Combined CTP- IGF-1 Score: A New Score for Assessment of Disease Severity in HCV Related Liver Cirrhosis

inferred← citeshttps://doi.org/10.2147/ijgm.s294505openalex-snapshot

Using Integrated Bioinformatics Analysis to Identify Abnormally Methylated Differentially Expressed Genes in Hepatocellular Carcinoma

inferred← citeshttps://doi.org/10.2147/jhc.s274933openalex-snapshot

Mechanisms Underlying Hepatocellular Carcinoma Progression in Patients with Type 2 Diabetes

inferred← citeshttps://doi.org/10.2147/jir.s415378openalex-snapshot

Polyhydroxylated Fullerene C60(OH)40 Nanofilms Promote the Mesenchymal–Epithelial Transition of Human Liver Cancer Cells via the TGF-β1/Smad Pathway

inferred← citeshttps://doi.org/10.21518/ms2025-223openalex-snapshot

L-Ornithine salts as somatotropic axis modulators for the correction of sarcopenia in chronic liver disease

inferred← citeshttps://doi.org/10.21608/ejchem.2023.151042.6607openalex-snapshot

Biochemical Studies on Amphiregulin protein in Hepatitis C virus patients

inferred← citeshttps://doi.org/10.21608/ejhm.2022.241722openalex-snapshot

Combined CTP-IGF-1 Score: A New Score for Assessment of Disease Severity in Patients With HCV- Related Liver Cirrhosis

inferred← citeshttps://doi.org/10.21608/mjcu.2022.264607openalex-snapshot

Role of LncRNA H19 in the Regulation of IGF-1R Expression: A Possible Association between Type 2 Diabetes and Hepatocellular Carcinoma: A Review Article

inferred← citeshttps://doi.org/10.2174/0115748855313087240719072514openalex-snapshot

Search for Novel Therapeutic Targets of Type 2 Diabetes Mellitus

inferred← citeshttps://doi.org/10.2174/1874467215666220103111009openalex-snapshot

Potential Therapeutic Strategies to Combat HCC

inferred← citeshttps://doi.org/10.2174/1875318302111010001openalex-snapshot

Insulin Growth Factor-1 as a Predictor for the Progression of Hepatic Disease in Chronic Hepatitis B Virus Infection

inferred← citeshttps://doi.org/10.21873/anticanres.14999openalex-snapshot

Obesity and Liver Cancer in Japan: A Comprehensive Review

inferred← citeshttps://doi.org/10.22358/jafs/194203/2024openalex-snapshot

Effects of dietary protein levels on growth and physiology of domesticated European perch (Perca fluviatilis) reared in a recirculating aquaculture system

inferred← citeshttps://doi.org/10.24875/rme.22000056openalex-snapshot

Resistencia a la insulina, hepatopatía grasa y su asociación con las proteínas acarreadoras de IGF

inferred← citeshttps://doi.org/10.25394/pgs.15044022.v1openalex-snapshot

Maternal Hepatic Adaptations to Pregnancy

inferred← citeshttps://doi.org/10.31351/vol30iss2pp1-15openalex-snapshot

An Overview of Some Plant Based Products With Hepatoprotective Activity

inferred← citeshttps://doi.org/10.3329/bjms.v21i2.58057openalex-snapshot

Mesenchymal Stem Cells Combined with Bovine Colostrum Decrease the PDGF and Fibrosis Level after Hepatectomy in Liver Fibrosis Rats Model

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