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TGF-β-Mediated Epithelial-Mesenchymal Transition and Cancer Metastasis
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3 of the 200 references listed on this page are in the Retraction Watch database as retracted (export 2026-10-28): 10.1002/jcb.26894 (notice 2020-12-15), 10.1038/nature12785 (notice 2015-07-10), 10.1089/dna.2016.3553 (notice 2022-04-01).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/2211-5463.12533openalex-snapshotLnc RNA UCA 1 is necessary for TGF ‐β‐induced epithelial–mesenchymal transition and stemness via acting as a ce RNA for Slug in glioma cells
inferredcites →https://doi.org/10.1002/cam4.1758openalex-snapshotTGF‐β‐mediated exosomal lnc‐MMP2‐2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression
inferredcites →https://doi.org/10.1002/cam4.724openalex-snapshotA phase I study of the human anti‐activin receptor‐like kinase 1 antibody PF ‐03446962 in Asian patients with advanced solid tumors
inferredcites →https://doi.org/10.1002/hep.26369openalex-snapshotMicroRNA-216a/217-Induced Epithelial-Mesenchymal Transition Targets Pten and SMAD7 to Promote Drug Resistance and Recurrence of Liver Cancer
inferredcites →https://doi.org/10.1002/hep.30153openalex-snapshotA Transforming Growth Factor‐β and H19 Signaling Axis in Tumor‐Initiating Hepatocytes That Regulates Hepatic Carcinogenesis
inferredcites →https://doi.org/10.1002/ijc.1599openalex-snapshotTransforming growth factor‐β and Ras regulate the VEGF/VEGF‐receptor system during tumor angiogenesis
inferredcites →https://doi.org/10.1002/ijc.31605openalex-snapshotLncRNA NKILA suppresses TGF‐β‐induced epithelial–mesenchymal transition by blocking NF‐κB signaling in breast cancer
inferredcites →https://doi.org/10.1002/jcb.20458openalex-snapshotInduction of an epithelial to mesenchymal transition in human immortal and malignant keratinocytes by TGF‐β1 involves MAPK, Smad and AP‐1 signalling pathways
inferredcites →https://doi.org/10.1002/jcb.26894openalex-snapshotRetracted: LncRNA ATB promotes proliferation and metastasis in A549 cells by down‐regulation of microRNA‐494
inferredcites →https://doi.org/10.1002/path.1327openalex-snapshotPromoter methylation of TGFβ receptor I and mutation of TGFβ receptor II are frequent events in MSI sporadic gastric carcinomas
inferredcites →https://doi.org/10.1007/s00262-011-1119-yopenalex-snapshotThe small molecule TGF-β signaling inhibitor SM16 synergizes with agonistic OX40 antibody to suppress established mammary tumors and reduce spontaneous metastasis
inferredcites →https://doi.org/10.1007/s00262-015-1653-0openalex-snapshotCutaneous keratoacanthomas/squamous cell carcinomas associated with neutralization of transforming growth factor β by the monoclonal antibody fresolimumab (GC1008)
inferredcites →https://doi.org/10.1007/s13277-016-5210-zopenalex-snapshotOverexpression of LncRNA-ROR predicts a poor outcome in gallbladder cancer patients and promotes the tumor cells proliferation, migration, and invasion
inferredcites →https://doi.org/10.1016/j.biopha.2018.01.162openalex-snapshotLncRNA-LET inhibits cell viability, migration and EMT while induces apoptosis by up-regulation of TIMP2 in human granulosa-like tumor cell line KGN
inferredcites →https://doi.org/10.1016/j.canlet.2018.01.036openalex-snapshotLong non-coding RNA XIST promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-367/141-ZEB2 axis in non-small-cell lung cancer
inferredcites →https://doi.org/10.1016/j.canlet.2018.06.013openalex-snapshotThe TGFβ-induced lncRNA TBILA promotes non-small cell lung cancer progression in vitro and in vivo via cis-regulating HGAL and activating S100A7/JAB1 signaling
inferredcites →https://doi.org/10.1016/j.ccell.2014.11.025openalex-snapshot14-3-3ζ Turns TGF-β’s Function from Tumor Suppressor to Metastasis Promoter in Breast Cancer by Contextual Changes of Smad Partners from p53 to Gli2
inferredcites →https://doi.org/10.1016/j.ccr.2006.11.023openalex-snapshotHigh TGFβ-Smad Activity Confers Poor Prognosis in Glioma Patients and Promotes Cell Proliferation Depending on the Methylation of the PDGF-B Gene
inferredcites →https://doi.org/10.1016/j.gene.2017.01.023openalex-snapshotLong noncoding RNA LINC01186, regulated by TGF-β/SMAD3, inhibits migration and invasion through Epithelial-Mesenchymal-Transition in lung cancer
inferredcites →https://doi.org/10.1016/j.immuni.2006.07.011openalex-snapshotTransforming Growth Factor-β Controls Development, Homeostasis, and Tolerance of T Cells by Regulatory T Cell-Dependent and -Independent Mechanisms
inferredcites →https://doi.org/10.1038/316701a0openalex-snapshotHuman transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells
inferredcites →https://doi.org/10.1038/387417a0openalex-snapshotRepression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-β in cells lacking the CDK inhibitor p15
inferredcites →https://doi.org/10.1038/cdd.2017.9openalex-snapshotDownregulation of Lnc-Spry1 mediates TGF-β-induced epithelial–mesenchymal transition by transcriptional and posttranscriptional regulatory mechanisms
inferredcites →https://doi.org/10.1038/cgt.2013.82openalex-snapshotCritical role of miR-10b in transforming growth factor-β1-induced epithelial–mesenchymal transition in breast cancer
inferredcites →https://doi.org/10.1038/nature16064openalex-snapshotEpithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
inferredcites →https://doi.org/10.1038/ncb1722openalex-snapshotThe miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
inferredcites →https://doi.org/10.1038/ncb1780openalex-snapshotThe type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner
inferredcites →https://doi.org/10.1038/ncb1905openalex-snapshotA SNAIL1–SMAD3/4 transcriptional repressor complex promotes TGF-β mediated epithelial–mesenchymal transition
inferredcites →https://doi.org/10.1038/ncb3613openalex-snapshotDifferential effects on lung and bone metastasis of breast cancer by Wnt signalling inhibitor DKK1
inferredcites →https://doi.org/10.1038/ncomms13884openalex-snapshotMicroRNA-182 targets SMAD7 to potentiate TGFβ-induced epithelial-mesenchymal transition and metastasis of cancer cells
inferredcites →https://doi.org/10.1038/ncomms3977openalex-snapshotmicroRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial–mesenchymal transition
inferredcites →https://doi.org/10.1038/ncomms8743openalex-snapshotMEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures
inferredcites →https://doi.org/10.1038/nm1001-1118openalex-snapshotImmune-mediated eradication of tumors through the blockade of transforming growth factor-β signaling in T cells
inferredcites →https://doi.org/10.1038/onc.2016.203openalex-snapshotPhosphorylation of serine 367 of FOXC2 by p38 regulates ZEB1 and breast cancer metastasis, without impacting primary tumor growth
inferredcites →https://doi.org/10.1038/onc.2016.260openalex-snapshotThe Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition
inferredcites →https://doi.org/10.1038/onc.2016.278openalex-snapshotThe long non-coding RNA, SNHG6-003, functions as a competing endogenous RNA to promote the progression of hepatocellular carcinoma
inferredcites →https://doi.org/10.1038/srep11924openalex-snapshotTGFβ1 secreted by cancer-associated fibroblasts induces epithelial-mesenchymal transition of bladder cancer cells through lncRNA-ZEB2NAT
inferredcites →https://doi.org/10.1074/jbc.m005912200openalex-snapshotPhosphatidylinositol 3-Kinase Function Is Required for Transforming Growth Factor β-mediated Epithelial to Mesenchymal Transition and Cell Migration
inferredcites →https://doi.org/10.1074/jbc.m104536200openalex-snapshotSynergistic Cooperation between Hypoxia and Transforming Growth Factor-β Pathways on Human Vascular Endothelial Growth Factor Gene Expression
inferredcites →https://doi.org/10.1074/jbc.m116.750950openalex-snapshotMEG3 Long Noncoding RNA Contributes to the Epigenetic Regulation of Epithelial-Mesenchymal Transition in Lung Cancer Cell Lines
inferredcites →https://doi.org/10.1074/jbc.ra118.004006openalex-snapshotMEG8 long noncoding RNA contributes to epigenetic progression of the epithelial-mesenchymal transition of lung and pancreatic cancer cells
inferredcites →https://doi.org/10.1083/jcb.114.4.827openalex-snapshotIdentification and analysis of discrete functional domains in the pro region of pre-pro-transforming growth factor beta 1.
inferredcites →https://doi.org/10.1089/cbr.2018.2503openalex-snapshotLong Noncoding RNA SNHG7 Promotes the Tumor Growth and Epithelial-to-Mesenchymal Transition via Regulation of miR-34a Signals in Osteosarcoma
inferredcites →https://doi.org/10.1089/gtmb.2018.0026openalex-snapshotKnockdown of LncRNA-XIST Suppresses Proliferation and TGF-β1-Induced EMT in NSCLC Through the Notch-1 Pathway by Regulation of miR-137
inferredcites →https://doi.org/10.1091/mbc.e11-02-0103openalex-snapshotAn autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition
inferredcites →https://doi.org/10.1093/jjco/hyv214openalex-snapshotHigh expression of long non-coding RNA lncRNA-ATB is correlated with metastases and promotes cell migration and invasion in renal cell carcinoma
inferredcites →https://doi.org/10.1111/cas.13626openalex-snapshotLong noncoding RNA NORAD regulates transforming growth factor‐β signaling and epithelial‐to‐mesenchymal transition‐like phenotype
inferredcites →https://doi.org/10.1111/cpr.12425openalex-snapshotLong noncoding RNA LINC 00978 promotes cancer growth and acts as a diagnostic biomarker in gastric cancer
inferredcites →https://doi.org/10.1111/jcmm.13439openalex-snapshotTRAF 6 regulates tumour metastasis through EMT and CSC phenotypes in head and neck squamous cell carcinoma
inferredcites →https://doi.org/10.1111/jgh.13206openalex-snapshotLncRNA‐ATB mediated E‐cadherin repression promotes the progression of colon cancer and predicts poor prognosis
inferredcites →https://doi.org/10.1126/scisignal.aak9557openalex-snapshotThe lncRNA H19 mediates breast cancer cell plasticity during EMT and MET plasticity by differentially sponging miR-200b/c and let-7b
inferredcites →https://doi.org/10.1128/mcb.00941-08openalex-snapshotMicroRNA-155 Is Regulated by the Transforming Growth Factor β/Smad Pathway and Contributes to Epithelial Cell Plasticity by Targeting RhoA
inferredcites →https://doi.org/10.1139/bcb-2018-0168openalex-snapshotDown-regulation of lncRNA-ATB inhibits epithelial–mesenchymal transition of breast cancer cells by increasing miR-141-3p expression
inferredcites →https://doi.org/10.1158/0008-5472.can-04-1013openalex-snapshotSD-208, a Novel Transforming Growth Factor β Receptor I Kinase Inhibitor, Inhibits Growth and Invasiveness and Enhances Immunogenicity of Murine and Human Glioma CellsIn vitroandIn vivo
inferredcites →https://doi.org/10.1158/0008-5472.can-05-3560openalex-snapshotThe Tumor Suppressor Smad4 Is Required for Transforming Growth Factor β–Induced Epithelial to Mesenchymal Transition and Bone Metastasis of Breast Cancer Cells
inferredcites →https://doi.org/10.1158/1078-0432.ccr-12-1703openalex-snapshotDetection of miR-34a Promoter Methylation in Combination with Elevated Expression of c-Met and β-Catenin Predicts Distant Metastasis of Colon Cancer
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4702361openalex-extractedTetrandrine Can Strengthen the Sensitivity and Reverse Drug Resistance of Gastric Carcinoma Organoids and Cells to 5-Fluorouracil
inferred← citeshttps://doi.org/10.1002/adbi.202000049openalex-snapshotReciprocal Signaling between Myeloid Derived Suppressor and Tumor Cells Enhances Cellular Motility and is Mediated by Structural Cues in the Microenvironment
inferred← citeshttps://doi.org/10.1002/adfm.202010283openalex-snapshotSequentially Targeting Cancer‐Associated Fibroblast and Mitochondria Alleviates Tumor Hypoxia and Inhibits Cancer Metastasis by Preventing “Soil” Formation and “Seed” Dissemination
inferred← citeshttps://doi.org/10.1002/advs.202002747openalex-snapshotLong Noncoding RNA HITTERS Protects Oral Squamous Cell Carcinoma Cells from Endoplasmic Reticulum Stress‐Induced Apoptosis via Promoting MRE11‐RAD50‐NBS1 Complex Formation
inferred← citeshttps://doi.org/10.1002/advs.202413389openalex-snapshotFerritin‐Based Supramolecular Assembly Drug Delivery System for Aminated Fullerene Derivatives to Enhance Tumor‐Targeted Therapy
inferred← citeshttps://doi.org/10.1002/cam4.2894openalex-snapshotFangjihuangqi Decoction inhibits MDA‐MB‐231 cell invasion in vitro and decreases tumor growth and metastasis in triple‐negative breast cancer xenografts tumor zebrafish model
inferred← citeshttps://doi.org/10.1002/cam4.6316openalex-snapshotIdentification of angiogenesis‐related genes signature for predicting survival and its regulatory network in glioblastoma
inferred← citeshttps://doi.org/10.1002/cbf.3742openalex-snapshotEvidence that cervical cancer cells cultured as tumorspheres maintain high CD73 expression and increase their protumor characteristics through TGF‐β production
inferred← citeshttps://doi.org/10.1002/cbf.3998openalex-snapshotThe PI3K/AKT/mTOR signaling pathway in breast cancer: Review of clinical trials and latest advances
inferred← citeshttps://doi.org/10.1002/cnr2.70632openalex-snapshotThe Prognostic Role of Vimentin Expression in Triple‐Negative Breast Cancer: A Retrospective Cohort Study
inferred← citeshttps://doi.org/10.1002/cso2.1015openalex-snapshotInvestigating epithelial‐mesenchymal heterogeneity of tumors and circulating tumor cells with transcriptomic analysis and biophysical modeling
inferred← citeshttps://doi.org/10.1002/cso2.1031openalex-snapshotMulticellular mechanochemical hybrid cellular Potts model of tissue formation during epithelial‐mesenchymal transition
inferred← citeshttps://doi.org/10.1002/cso2.1044openalex-snapshotA review of computational modeling, machine learning and image analysis in cancer metastasis dynamics
inferred← citeshttps://doi.org/10.1002/ctm2.1475openalex-snapshotLoss of SETD2 aggravates colorectal cancer progression caused by SMAD4 deletion through the RAS/ERK signalling pathway
inferred← citeshttps://doi.org/10.1002/ddr.22019openalex-snapshotAnlotinib improves bile duct ligature‐induced liver fibrosis in rats via antiangiogenesis regulated by VEGFR2/mTOR pathway
inferred← citeshttps://doi.org/10.1002/jbt.70047openalex-snapshotThe Pro‐Migratory and Pro‐Invasive Roles of Cancer‐Associated Fibroblasts Secreted IL‐17A in Prostate Cancer
inferred← citeshttps://doi.org/10.1002/jbt.70166openalex-snapshotExploring the Role of Epithelial–Mesenchymal Transition During Colorectal Cancer Peritoneal Metastasis: Update on Their Mechanisms
inferred← citeshttps://doi.org/10.1002/jbt.70336openalex-snapshotMiR‐155‐5p Inhibits Multiple Myeloma Cell Malignancy and Tumorigenesis by Targeting JARID2 and Inactivating the TGFβ/SMAD2 Signaling
inferred← citeshttps://doi.org/10.1002/jbt.70804openalex-snapshotOnonin Inhibits the Growth and Metastasis of Hepatocellular Carcinoma by Suppressing MMP‐2 and MMP‐9 via PI3K/AKT/mTOR Signaling
inferred← citeshttps://doi.org/10.1002/jbt.71066openalex-snapshot4‐FPAC‐Modulated Tumor‐Associated Macrophage Conditioned Media Suppresses Malignant Phenotypes and Promotes Cell‐Cycle Arrest and Apoptosis in NSCLC
inferred← citeshttps://doi.org/10.1002/jcla.24609openalex-snapshotThe intercorrelation among CCT6A , CDC20 , CCNB1 , and PLK1 expressions and their clinical value in papillary thyroid carcinoma prognostication
inferred← citeshttps://doi.org/10.1002/jcp.31481openalex-snapshotFMNL3 Promotes Migration and Invasion of Breast Cancer Cells via Inhibiting Rad23B‐Induced Ubiquitination of Twist1
inferred← citeshttps://doi.org/10.1002/mc.23205openalex-snapshotThe interplay between cancer associated fibroblasts and immune cells in the context of radiation therapy
inferred← citeshttps://doi.org/10.1002/mc.23350openalex-snapshotFOXD3 suppresses epithelial–mesenchymal transition through direct transcriptional promotion of SMAD7 in esophageal squamous cell carcinoma
inferred← citeshttps://doi.org/10.1002/mc.23484openalex-snapshotThe TGF‐β/Smad2/3 signaling pathway is involved in Musashi2‐induced invasion and metastasis of colorectal cancer
inferred← citeshttps://doi.org/10.1002/mc.23711openalex-snapshotEffect of CHRDL1 on angiogenesis and metastasis of colorectal cancer cells via TGF‐β/VEGF pathway
inferred← citeshttps://doi.org/10.1002/mc.23731openalex-snapshotMicroRNA‐431‐5p inhibits angiogenesis, lymphangiogenesis, and lymph node metastasis by affecting TGF‐β1/SMAD2/3 signaling via ZEB1 in gastric cancer
inferred← citeshttps://doi.org/10.1002/med.21886openalex-snapshotTargeting key proteins involved in transcriptional regulation for cancer therapy: Current strategies and future prospective
inferred← citeshttps://doi.org/10.1002/mnfr.202200248openalex-snapshotPiceatannol Prevents Colon Cancer Progression via Dual‐Targeting to M2‐Polarized Tumor‐Associated Macrophages and the TGF‐β1 Positive Feedback Signaling Pathway
inferred← citeshttps://doi.org/10.1002/mog2.70027openalex-snapshotTransforming Growth Factor‐Beta Signaling in Cancer: Therapeutic Implications, Challenges, and Pathways to Progress
inferred← citeshttps://doi.org/10.1002/path.6223openalex-snapshotMechanisms of carboplatin‐ and paclitaxel‐dependent induction of premature senescence and pro‐cancerogenic conversion of normal peritoneal mesothelium and fibroblasts
inferred← citeshttps://doi.org/10.1002/path.6240openalex-snapshotA partial epithelial‐mesenchymal transition signature for highly aggressive colorectal cancer cells that survive under nutrient restriction
inferred← citeshttps://doi.org/10.1002/path.70013openalex-snapshotRelative MYC downregulation and RUNX2 upregulation orchestrate partial epithelial‐mesenchymal transition in colorectal cancer tumor budding and poorly differentiated clusters
inferred← citeshttps://doi.org/10.1002/ptr.8363openalex-snapshotNovel Perspectives in the Management of Colorectal Cancer: Mechanistic Investigations Into the Reversal of Drug Resistance via Active Constituents Derived From Herbal Medicine
inferred← citeshttps://doi.org/10.1002/smll.74724openalex-snapshotInhalable Degradation‐Tunable Hybrid Nanoparticles With Rapid Lysosomal Escape for Dual siRNA Therapy Against NSCLC
inferred← citeshttps://doi.org/10.1002/tox.24082openalex-snapshotComprehensive analyses and experimental verification of NETs and an EMT gene signature for prognostic prediction, immunotherapy, and chemotherapy in pancreatic adenocarcinoma
inferred← citeshttps://doi.org/10.1007/s00018-020-03544-5openalex-snapshotTGF-β1 promotes epithelial-to-mesenchymal transition and stemness of prostate cancer cells by inducing PCBP1 degradation and alternative splicing of CD44
inferred← citeshttps://doi.org/10.1007/s00018-025-05781-yopenalex-snapshotFibroblasts activated by miRs-185-5p, miR-652-5p, and miR-1246 shape the tumor microenvironment in triple-negative breast cancer via PATZ1 downregulation
inferred← citeshttps://doi.org/10.1007/s00210-024-03279-1openalex-snapshotNatural products and long noncoding RNA signatures in gallbladder cancer: a review focuses on pathogenesis, diagnosis, and drug resistance
inferred← citeshttps://doi.org/10.1007/s10142-026-01859-3openalex-snapshotSingle-cell and spatial transcriptomics reveal TNF-α promotes glioblastoma proliferation and migration via CP-mediated KLF10 upregulation
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