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The Molecular Mechanism of Perillaldehyde Inducing Cell Death in Aspergillus flavus by Inhibiting Energy Metabolism Revealed by Transcriptome Sequencing

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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AtfA bZIP-type transcription factor regulates oxidative and osmotic stress responses in Aspergillus nidulans

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ROS-dependent signal transduction

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Hypolipidemic potential of perillaldehyde-loaded self-nanoemulsifying delivery system in high-fat diet induced hyperlipidemic mice: Formulation, in vitro and in vivo evaluation

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Biological effects of essential oils – A review

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Genotoxicity assessment of the flavouring agent, perillaldehyde

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Regulation of the yeast phospholipid hydroperoxide glutathione peroxidase GPX2 by oxidative stress is mediated by Yap1 and Skn7

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The system biology of thiol redox system in Escherichia coli and yeast: Differential functions in oxidative stress, iron metabolism and DNA synthesis

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Piperine inhibits aflatoxin B1 production in Aspergillus flavus by modulating fungal oxidative stress response

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Inhibitory effect of nerol against Aspergillus niger on grapes through a membrane lesion mechanism

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Efficacy and possible mechanisms of perillaldehyde in control of Aspergillus niger causing grape decay

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The Thioredoxin Specificity of Drosophila GPx: A Paradigm for a Peroxiredoxin-like Mechanism of many Glutathione Peroxidases

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Perillaldehyde, a potential preservative agent in foods: Assessment of antifungal activity against microbial spoilage of cherry tomatoes

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Dif1 Is a DNA-Damage-Regulated Facilitator of Nuclear Import for Ribonucleotide Reductase

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The pentose phosphate pathway and cancer

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6-phosphofructokinase (pyrophosphate). Properties of the enzyme from Entamoeba histolytica and its reaction mechanism.

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Perillaldehyde, a Promising Antifungal Agent Used in Food Preservation, Triggers Apoptosis through a Metacaspase-Dependent Pathway in Aspergillus flavus

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Intestinal Anti-Inflammatory Activity of Perillaldehyde

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Carvone and Perillaldehyde Interfere with the Serum-Induced Formation of Filamentous Structures in Candida a lbicans at Substantially Lower Concentrations than Those Causing Significant Inhibition of Growth

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Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration

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Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors

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Global Phosphoproteomic Analysis Reveals the Involvement of Phosphorylation in Aflatoxins Biosynthesis in the Pathogenic Fungus Aspergillus flavus

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How mitochondria produce reactive oxygen species

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Importance of catalase in the adaptive response to hydrogen peroxide: analysis of acatalasaemic Saccharomyces cerevisiae

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The hexokinase 2 protein regulates the expression of the GLK1, HXK1 and HXK2 genes of Saccharomyces cerevisiae

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Yeast glutathione reductase is required for protection against oxidative stress and is a target gene for yAP‐1 transcriptional regulation

inferredcites →https://doi.org/10.1046/j.1365-2958.2003.03554.xopenalex-snapshot

Glycerol dehydrogenase, encoded by gldB is essential for osmotolerance in Aspergillus nidulans

inferredcites →https://doi.org/10.1074/jbc.270.48.28635openalex-snapshot

Thioredoxin-linked "Thiol Peroxidase" from Periplasmic Space of Escherichia coli

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Yap1 and Skn7 Control Two Specialized Oxidative Stress Response Regulons in Yeast

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Serine Palmitoyltransferase Regulates de NovoCeramide Generation during Etoposide-induced Apoptosis

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Mitochondria of Saccharomyces cerevisiae Contain One-conserved Cysteine Type Peroxiredoxin with Thioredoxin Peroxidase Activity

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Thioredoxin Reductase-2 Is Essential for Keeping Low Levels of H2O2 Emission from Isolated Heart Mitochondria

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The Yeast Glutaredoxins Are Active as Glutathione Peroxidases

inferredcites →https://doi.org/10.1074/jbc.m200636200openalex-snapshot

Thioredoxin-2 but Not Thioredoxin-1 Is a Substrate of Thioredoxin Peroxidase-1 from Drosophila melanogaster

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GSTB1-1 from Proteus mirabilis

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Thioredoxin 2, an Oxidative Stress-induced Protein, Contains a High Affinity Zinc Binding Site

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Alternative Start Sites in the Saccharomyces cerevisiae GLR1 Gene Are Responsible for Mitochondrial and Cytosolic Isoforms of Glutathione Reductase

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The Saccharomyces cerevisiae Proteome of Oxidized Protein Thiols

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Antibacterial and Antifungal Properties of Essential Oil Components

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Glutathione and apoptosis

inferredcites →https://doi.org/10.1089/omi.2011.0118openalex-snapshot

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

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Atg17 Functions in Cooperation with Atg1 and Atg13 in Yeast Autophagy

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A novel NADH kinase is the mitochondrial source of NADPH in Saccharomyces cerevisiae

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Yeast Adapts to a Changing Stressful Environment by Evolving Cross-Protection and Anticipatory Gene Regulation

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The KEGG resource for deciphering the genome

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limma powers differential expression analyses for RNA-sequencing and microarray studies

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STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

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Conserved homeodomain proteins interact with MADS box protein Mcm1 to restrict ECB-dependent transcription to the M/G1 phase of the cell cycle

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Aspergillus flavus : the major producer of aflatoxin

inferredcites →https://doi.org/10.1111/j.1742-4658.2005.04749.xopenalex-snapshot

Identification of ATP‐NADH kinase isozymes and their contribution to supply of NADP(H) in Saccharomyces cerevisiae

inferredcites →https://doi.org/10.1111/mmi.13484openalex-snapshot

The Aspergillus fumigatus SchASCH9 kinase modulates SakAHOG1 MAP kinase activity and it is essential for virulence

inferredcites →https://doi.org/10.1111/ppa.12937openalex-snapshot

Induced cell death in Ceratocystis fimbriata by pro‐apoptotic activity of a natural organic compound, perillaldehyde, through Ca 2+ overload and accumulation of reactive oxygen species

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Autophagy as a Regulated Pathway of Cellular Degradation

inferredcites →https://doi.org/10.1128/aem.56.12.3686-3692.1990openalex-snapshot

Isolation and sequence analysis of a beta-tubulin gene from Aspergillus flavus and its use as a selectable marker

inferredcites →https://doi.org/10.1128/aem.68.6.2802-2808.2002openalex-snapshot

A Gene from Aspergillus nidulans with Similarity to URE2 of Saccharomyces cerevisiae Encodes a Glutathione S -Transferase Which Contributes to Heavy Metal and Xenobiotic Resistance

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Genome Sequence of Aspergillus flavus NRRL 3357, a Strain That Causes Aflatoxin Contamination of Food and Feed

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Oxidative Stress-Activated Zinc Cluster Protein Stb5 Has Dual Activator/Repressor Functions Required for Pentose Phosphate Pathway Regulation and NADPH Production

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Two-Component Signaling Regulates Osmotic Stress Adaptation via SskA and the High-Osmolarity Glycerol MAPK Pathway in the Human Pathogen Talaromyces marneffei

inferredcites →https://doi.org/10.1146/annurev-phyto-072910-095221openalex-snapshot

Aspergillus flavus

inferredcites →https://doi.org/10.1146/annurev.phyto.25.1.249openalex-snapshot

Epidemiology Of Aflatoxin Formation By Aspergillus Flavus

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TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

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Swe1 and Mih1 regulate mitotic spindle dynamics in budding yeast via Bik1

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Antimicrobial Effect of trans-Cinnamaldehyde, (-)-Perillaldehyde, (-)-Citronellal, Citral, Eugenol and Carvacrol on Airborne Microbes Using an Airwasher

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Thousands of exon skipping events differentiate among splicing patterns in sixteen human tissues

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Thousands of exon skipping events differentiate among splicing patterns in sixteen human tissues

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Aflatoxin Contamination of Commercial Maize Products during an Outbreak of Acute Aflatoxicosis in Eastern and Central Kenya

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Sen1p Contributes to Genomic Integrity by Regulating Expression of Ribonucleotide Reductase 1 (RNR1) in Saccharomyces cerevisiae

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Peroxiredoxins in Regulation of MAPK Signalling Pathways; Sensors and Barriers to Signal Transduction

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Metals, Toxicity and Oxidative Stress

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Effect of Perillaldehyde on Prophylaxis and Treatment of Vaginal Candidiasis in a Murine Model

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