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Optimizing an Osteosarcoma-Fibroblast Coculture Model to Study Antitumoral Activity of Magnesium-Based Biomaterials
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Corrosion of Mg alloy AZ91D in the presence of living cells
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Influence of MC 3 T 3‐ E 1 preosteoblast culture on the corrosion of a T 6‐treated AZ 91 alloy
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The Epidemiology of Osteosarcoma
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Contact inhibition in tissue culture
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In vitro degradation behavior and cytocompatibility of Mg–Zn–Zr alloys
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Hydroxyapatite coating on magnesium with MgF2 interlayer for enhanced corrosion resistance and biocompatibility
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Effect of extracellular Mg2+ concentration on agonist-induced cytosolic free Ca2+ transients
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Research on Colorectal Cancer in China
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The history of biodegradable magnesium implants: A review☆
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Effect of magnesium-degradation products and hypoxia on the angiogenesis of human umbilical vein endothelial cells
inferredcites →https://doi.org/10.1016/j.actbio.2019.10.014openalex-snapshot
Inflammatory response to magnesium-based biodegradable implant materials
inferredcites →https://doi.org/10.1016/j.bbadis.2004.08.003openalex-snapshot
Magnesium deficiency inhibits primary tumor growth but favors metastasis in mice
inferredcites →https://doi.org/10.1016/j.bioactmat.2018.01.003openalex-snapshot
Magnesium degradation under physiological conditions – Best practice
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Hydrogen gas inhibits lung cancer progression through targeting SMC3
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Hallmarks of Cancer: The Next Generation
inferredcites →https://doi.org/10.1016/j.cellsig.2015.08.006openalex-snapshot
Calcium signaling and cell proliferation
inferredcites →https://doi.org/10.1016/j.colsurfb.2015.01.015openalex-snapshot
Influence of living cells (L929) on the biodegradation of magnesium–calcium alloy
inferredcites →https://doi.org/10.1016/j.ctrv.2009.01.003openalex-snapshot
Magnesium and tumors: Ally or foe?
inferredcites →https://doi.org/10.1016/j.ejca.2011.05.030openalex-snapshot
Chemotherapeutic adjuvant treatment for osteosarcoma: Where do we stand?
inferredcites →https://doi.org/10.1016/j.ejmech.2014.07.012openalex-snapshot
Synthesis and characterization of silver nanoparticles using crystal compound of sodium para-hydroxybenzoate tetrahydrate isolated from Vitex negundo. L leaves and its apoptotic effect on human colon cancer cell lines
inferredcites →https://doi.org/10.1016/j.jmst.2014.03.004openalex-snapshot
Cytotoxic Effects of Biodegradation of Pure Mg and MAO-Mg on Tumor Cells of MG63 and KB
inferredcites →https://doi.org/10.1016/j.jmst.2014.04.010openalex-snapshot
Cytotoxic Effect on Osteosarcoma MG-63 Cells by Degradation of Magnesium
inferredcites →https://doi.org/10.1016/j.mseb.2011.04.008openalex-snapshot
Improved cytotoxicity testing of magnesium materials
inferredcites →https://doi.org/10.1016/j.mseb.2011.05.032openalex-snapshot
In vitro degradation performance and biological response of a Mg–Zn–Zr alloy
inferredcites →https://doi.org/10.1016/s1005-0302(12)60128-5openalex-snapshot
Preliminary Study on Cytotoxic Effect of Biodegradation of Magnesium on Cancer Cells
inferredcites →https://doi.org/10.1017/upo9780987073051openalex-snapshot
Magnesium in the Central Nervous System
inferredcites →https://doi.org/10.1017/upo9780987073051.017openalex-snapshot
Magnesium in cancer: more questions than answers
inferredcites →https://doi.org/10.1021/acsami.6b01747openalex-snapshot
Cell Adhesion on Surface-Functionalized Magnesium
inferredcites →https://doi.org/10.1023/a:1017972622312openalex-snapshot
Inhibitory effects of extracellular Mg2+ on intracellular Ca2+ dynamic changes and thapsigargin-induced apoptosis in human cancer MCF7 cells
inferredcites →https://doi.org/10.1038/35077241openalex-snapshot
The microenvironment of the tumour–host interface
inferredcites →https://doi.org/10.1038/nrc.2016.73openalex-snapshot
The biology and function of fibroblasts in cancer
inferredcites →https://doi.org/10.1038/nrc3038openalex-snapshot
Otto Warburg's contributions to current concepts of cancer metabolism
inferredcites →https://doi.org/10.1038/srep04384openalex-snapshot
Near-infrared fluorescence imaging of cancer cells and tumors through specific biosynthesis of silver nanoclusters
inferredcites →https://doi.org/10.1038/srep27902openalex-snapshot
Silver nanoparticles defeat p53-positive and p53-negative osteosarcoma cells by triggering mitochondrial stress and apoptosis
inferredcites →https://doi.org/10.1039/c2mt20039bopenalex-snapshot
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inferredcites →https://doi.org/10.1039/c3mt00046jopenalex-snapshot
Anti-proliferative and anti-tumor activity of silver(i) compounds
inferredcites →https://doi.org/10.1039/c3tb21604gopenalex-snapshot
The role of material structure and mechanical properties in cell–matrix interactions
inferredcites →https://doi.org/10.1051/sicotj/2017028openalex-snapshot
Osteosarcoma: a comprehensive review
inferredcites →https://doi.org/10.1073/pnas.0604460103openalex-snapshot
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inferredcites →https://doi.org/10.1074/jbc.m112.393918openalex-snapshot
Increase in Serum Ca2+/Mg2+ Ratio Promotes Proliferation of Prostate Cancer Cells by Activating TRPM7 Channels
inferredcites →https://doi.org/10.1080/14737140.2018.1413939openalex-snapshot
Current and future therapeutic approaches for osteosarcoma
inferredcites →https://doi.org/10.1084/jem.20140692openalex-snapshot
Fibroblast heterogeneity in the cancer wound
inferredcites →https://doi.org/10.1093/rb/rbx004openalex-snapshot
Corrosion and biocompatibility improvement of magnesium-based alloys as bone implant materials: a review
inferredcites →https://doi.org/10.1111/febs.14986openalex-snapshot
Metal ions and the extracellular matrix in tumor migration
inferredcites →https://doi.org/10.1111/j.1582-4934.2010.01168.xopenalex-snapshot
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inferredcites →https://doi.org/10.1152/physrev.00013.2019openalex-snapshot
Stiffness Sensing by Cells
inferredcites →https://doi.org/10.1155/2007/175276openalex-snapshot
The Carcinoma–Stromal Ratio of Colon Carcinoma Is an Independent Factor for Survival Compared to Lymph Node Status and Tumor Stage
inferredcites →https://doi.org/10.1155/2017/8091265openalex-snapshot
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inferredcites →https://doi.org/10.1158/0008-5472.can-08-4859openalex-snapshot
The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells
inferredcites →https://doi.org/10.1159/000320711openalex-snapshot
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inferredcites →https://doi.org/10.1161/01.cir.95.11.2567openalex-snapshot
Extracellular Mg 2+ Inhibits Capacitative Ca 2+ Entry in Vascular Smooth Muscle Cells
inferredcites →https://doi.org/10.1186/1750-1172-2-6openalex-snapshot
Osteosarcoma (Osteogenic sarcoma)
inferredcites →https://doi.org/10.1186/1756-9966-29-148openalex-snapshot
Antitumor activity of colloidal silver on MCF-7 human breast cancer cells
inferredcites →https://doi.org/10.1200/jco.2009.27.0421openalex-snapshot
Outcomes for Children and Adolescents With Cancer: Challenges for the Twenty-First Century
inferredcites →https://doi.org/10.1371/journal.pone.0050804openalex-snapshot
Epithelial-Stromal Interactions in Human Breast Cancer: Effects on Adhesion, Plasma Membrane Fluidity and Migration Speed and Directness
inferredcites →https://doi.org/10.1371/journal.pone.0142117openalex-snapshot
Influence of Magnesium Alloy Degradation on Undifferentiated Human Cells
inferredcites →https://doi.org/10.1371/journal.pone.0157874openalex-snapshot
The Degradation Interface of Magnesium Based Alloys in Direct Contact with Human Primary Osteoblast Cells
inferredcites →https://doi.org/10.1371/journal.pone.0182039openalex-snapshot
Pancreatic cancer cell/fibroblast co-culture induces M2 like macrophages that influence therapeutic response in a 3D model
inferredcites →https://doi.org/10.14694/edbook_am.2015.35.e644openalex-snapshot
Systemic Therapy for Osteosarcoma and Ewing Sarcoma
inferredcites →https://doi.org/10.1533/9780857096760openalex-snapshot
Biomaterials for cancer therapeutics
inferredcites →https://doi.org/10.1684/mrh.2015.0375openalex-snapshot
Magnesium-based implants: a mini-review
inferredcites →https://doi.org/10.18632/oncotarget.4902openalex-snapshot
Changes in the gene expression of co-cultured human fibroblast cells and osteosarcoma cells: the role of microenvironment
inferredcites →https://doi.org/10.22203/ecm.v024a01openalex-snapshot
In search of an osteoblast cell model for in vitro research
inferredcites →https://doi.org/10.22203/ecm.v025a20openalex-snapshot
Antibacterial biodegradable Mg-Ag alloys
inferredcites →https://doi.org/10.3390/ijms19072030openalex-snapshot
A Current Overview of the Biological and Cellular Effects of Nanosilver
inferredcites →https://doi.org/10.3390/ijms20020255openalex-snapshot
Improved In Vitro Test Procedure for Full Assessment of the Cytocompatibility of Degradable Magnesium Based on ISO 10993-5/-12
inferredcites →https://doi.org/10.3892/ol.2016.4289openalex-snapshot
ASF-4-1 fibroblast-rich culture increases chemoresistance and mTOR expression of pancreatic cancer BxPC-3 cells at the invasive front in vitro, and promotes tumor growth and invasion in vivo
inferredcites →https://doi.org/10.4103/0019-5413.132491openalex-snapshot
Classification, imaging, biopsy and staging of osteosarcoma
inferredcites →https://doi.org/10.4161/21592527.2014.967616openalex-snapshot
Comparison of the reaction of bone-derived cells to enhanced MgCl2-salt concentrations
inferredcites →https://doi.org/10.4161/cc.9.16.12553openalex-snapshot
Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4796132openalex-extracted
Bone Cells Influence on the Degradation Interface of Mg-Based Materials: Insights from Multimodal In Vitro Analysis
inferred← citeshttps://doi.org/10.1002/jbm.a.37862openalex-snapshot
Investigating the Potential of Magnesium Microparticles on Cartilage and Bone Regeneration Utilizing an In Vitro Osteoarthritis Model
inferred← citeshttps://doi.org/10.1002/jcp.31256openalex-snapshot
Osteosarcoma cell death induced by innovative scaffolds doped with chemotherapeutics
inferred← citeshttps://doi.org/10.1007/978-3-030-92533-8_3openalex-snapshot
The Comparability of In Vitro and In Vivo Experiments for Degradable Mg Implants
inferred← citeshttps://doi.org/10.1016/j.actbio.2024.02.018openalex-snapshot
Magnesium-lithium thin films for neurological applications–An in vitro investigation of glial cytocompatibility and neuroinflammatory response
inferred← citeshttps://doi.org/10.1016/j.actbio.2024.08.015openalex-snapshot
Bone cells influence the degradation interface of pure Mg and WE43 materials: Insights from multimodal in vitro analysis
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2021.12.031openalex-snapshot
Slow degrading Mg-based materials induce tumor cell dormancy on an osteosarcoma-fibroblast coculture model
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2022.05.002openalex-snapshot
Mg-based materials diminish tumor spreading and cancer metastases
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2025.12.039openalex-snapshot
A promising magnesium-related alloy with metabolic reprogramming and antitumor effects in hepatocellular and pancreatic cancer
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2025.123263openalex-snapshot
Implant derived high local concentration of magnesium inhibits tumorigenicity of osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.ceramint.2021.08.181openalex-snapshot
Mixed phase bioceramics in the CaMgSi2O6 – MoO3 system: Mechanical properties and in-vitro bioactivity
inferred← citeshttps://doi.org/10.1016/j.corsci.2026.113922openalex-snapshot
An investigation into the direct influence of normal human dermal fibroblasts on magnesium degradation in a microfluidic system
inferred← citeshttps://doi.org/10.1016/j.jma.2023.08.008openalex-snapshot
Magnesium alloys in tumor treatment: Current research status, challenges and future prospects
inferred← citeshttps://doi.org/10.1016/j.jma.2026.102338openalex-snapshot
Reprogramming the post-resection niche of primary malignant bone tumors: Biological opportunities, engineering limits and translational requirements of magnesium-based implants
inferred← citeshttps://doi.org/10.1016/j.jmbbm.2023.105939openalex-snapshot
Strength and ductility loss of Magnesium-Gadolinium due to corrosion in physiological environment: Experiments and modeling
inferred← citeshttps://doi.org/10.1063/5.0191800openalex-snapshot
Mg alloys with antitumor and anticorrosion properties for orthopedic oncology: A review from mechanisms to application strategies
inferred← citeshttps://doi.org/10.1111/jcmm.71111openalex-snapshot
Gene Expression Alterations Associated With Resveratrol‐Induced Antiproliferative Effects and S‐Phase Cell Cycle Arrest in Osteosarcoma Cancer Cells
inferred← citeshttps://doi.org/10.1186/s13619-025-00225-1openalex-snapshot
Revolutionizing bone healing: the role of 3D models
inferred← citeshttps://doi.org/10.3389/fcell.2021.646032openalex-snapshot
Long Non-coding RNAs and MicroRNAs Interplay in Osteogenic Differentiation of Mesenchymal Stem Cells
inferred← citeshttps://doi.org/10.3389/fphys.2025.1661054openalex-snapshot
Tissue stiffness heterogeneity in the jaw and temporomandibular joint: its impact on tumor metabolism and considerations for in vitro model development
inferred← citeshttps://doi.org/10.3390/cryst11111381openalex-snapshot
Rationale for Processing of a Mg-Zn-Ca Alloy by Equal-Channel Angular Pressing for Use in Biodegradable Implants for Osteoreconstruction
inferred← citeshttps://doi.org/10.3390/ijms22052362openalex-snapshot
MicroRNAs Modulate Signaling Pathways in Osteogenic Differentiation of Mesenchymal Stem Cells
inferred← citeshttps://doi.org/10.5772/intechopen.1011167openalex-snapshot
Transplantation of MSCs for a Longstanding Engraftment and Maintenance of Bone Marrow Stroma
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