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The Neurovascular Unit Dysfunction in Alzheimer’s Disease
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Hereditary Cerebral Hemorrhage With Amyloidosis Associated With the E693K Mutation of APP
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RAGE, LRP-1, and amyloid-beta protein in Alzheimer’s disease
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Roles of tau protein in health and disease
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Age-related plaque morphology and C-terminal heterogeneity of amyloid β in Dutch-type hereditary cerebral hemorrhage with amyloidosis
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Nanotechnology to improve the Alzheimer’s disease therapy with natural compounds
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Tau protein and the neurofibrillary pathology of Alzheimer's disease
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The impact of neurovascular, blood-brain barrier, and glymphatic dysfunction in neurodegenerative and metabolic diseases
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Brain cancer diagnosis and therapy with nanoplatforms☆
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Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: The case for isradipine
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The role of insulin in the vascular contributions to age-related dementia
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Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease
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γ-Secretase inhibitors and modulators
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Protective effects of cationic bovine serum albumin-conjugated PEGylated tanshinone IIA nanoparticles on cerebral ischemia
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The effect of cationic albumin-conjugated PEGylated tanshinone IIA nanoparticles on neuronal signal pathways and neuroprotection in cerebral ischemia
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ABC efflux transporters in brain vasculature of Alzheimer's subjects
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Establishment and Dysfunction of the Blood-Brain Barrier
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Interaction of natural compounds with biomembrane models: A biophysical approach for the Alzheimer’s disease therapy
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Molecular Trojan horses for blood–brain barrier drug delivery
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Blood–brain barrier delivery
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Glucagon like peptide-1 (GLP-1) likes Alzheimer’s disease
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Traumatic Brain Injury and Alzheimer's Disease: The Cerebrovascular Link
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Selective targeting of a TNFR decoy receptor pharmaceutical to the primate brain as a receptor-specific IgG fusion protein
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Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases
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Memantine mediates neuroprotection via regulating neurovascular unit in a mouse model of focal cerebral ischemia
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Mechanism mediating oligomeric Aβ clearance by naïve primary microglia
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Angiotensin II type 1 receptor blocker losartan prevents and rescues cerebrovascular, neuropathological and cognitive deficits in an Alzheimer’s disease model
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Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment
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The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
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Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging
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The Pathobiology of Vascular Dementia
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The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease
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TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function
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Aquaporin-4 in the central nervous system: Cellular and subcellular distribution and coexpression with KIR4.1
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Una revisión de los avances en la terapéutica de la enfermedad de Alzheimer: estrategia frente a la proteína β-amiloide
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Review of the advances in treatment for Alzheimer disease: strategies for combating β-amyloid protein
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Effects of a behaviorally active antibody on the brain uptake and clearance of amyloid beta proteins
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Targeting the neurovascular unit for treatment of neurological disorders
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Functions and mechanisms of microglia/macrophages in neuroinflammation and neurogenesis after stroke
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HI 6 human serum albumin nanoparticles—Development and transport over an in vitro blood–brain barrier model
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Active Aβ immunotherapy CAD106 in Alzheimer's disease: A phase 2b study
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The effects of noncoding aquaporin‐4 single‐nucleotide polymorphisms on cognition and functional progression of Alzheimer's disease
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Ponezumab in mild‐to‐moderate Alzheimer's disease: Randomized phase II PET‐PIB study
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The TOMMORROW study: Design of an Alzheimer's disease delay‐of‐onset clinical trial
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Chapter 22: Localization patterns for immunoglobulins and albumins in the brain suggest diverse mechanisms for their transport across the blood-brain barrier (BBB)
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Passage of amyloid β protein antibody across the blood–brain barrier in a mouse model of Alzheimer’s disease
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Matrix metalloproteinases and their multiple roles in neurodegenerative diseases
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Neuroinflammation in Alzheimer's disease
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The glymphatic pathway in neurological disorders
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A Knowledge-Based Approach in Designing Combinatorial or Medicinal Chemistry Libraries for Drug Discovery. 1. A Qualitative and Quantitative Characterization of Known Drug Databases
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Acetylcholinesterase inhibitors, neuropsychiatric symptoms, and Alzheimer's disease subtypes: An alternate hypothesis to global cognitive enhancement.
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Scavenger receptor-mediated adhesion of microglia to β-amyloid fibrils
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Blood–Brain Barrier Dysfunction as a Cause and Consequence of Alzheimer's Disease
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Layer-Specific Dilation of Penetrating Arteries Induced by Stimulation of the Nucleus Basalis of Meynert in the Mouse Frontal Cortex
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Pial Arteries Respond Earlier than Penetrating Arterioles to Neural Activation in the Somatosensory Cortex in Awake Mice Exposed to Chronic Hypoxia: An Additional Mechanism to Proximal Integration Signaling?
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Dexamethasone Potentiates in Vitro Blood-Brain Barrier Recovery after Primary Blast Injury by Glucocorticoid Receptor-Mediated Upregulation of ZO-1 Tight Junction Protein
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Pericytes regulate the blood–brain barrier
inferredcites →https://doi.org/10.1038/nature09613openalex-snapshot
Glial and neuronal control of brain blood flow
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Neurotoxic reactive astrocytes are induced by activated microglia
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SRF and myocardin regulate LRP-mediated amyloid-β clearance in brain vascular cells
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Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models
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Cerebral vascular amyloid seeds drive amyloid β-protein fibril assembly with a distinct anti-parallel structure
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CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
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Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease
inferredcites →https://doi.org/10.1038/nm890openalex-snapshot
RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain
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Central nervous system pericytes in health and disease
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A fluoro-Nissl dye identifies pericytes as distinct vascular mural cells during in vivo brain imaging
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Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
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Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease
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Neurovascular regulation in the normal brain and in Alzheimer's disease
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Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
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The many faces of insulin-like peptide signalling in the brain
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Clearance systems in the brain—implications for Alzheimer disease
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Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders
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Tau-targeting therapies for Alzheimer disease
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Cerebral amyloid angiopathy and Alzheimer disease — one peptide, two pathways
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VEGF significantly restores impaired memory behavior in Alzheimer's mice by improvement of vascular survival
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Paravascular microcirculation facilitates rapid lipid transport and astrocyte signaling in the brain
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Angiotensin II AT1 receptor blockers as treatments for inflammatory brain disorders
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Astrocyte–endothelial interactions and blood–brain barrier permeability*
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Expression of the neonatal Fc receptor (FcRn) at the blood–brain barrier
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Complement protein C5a enhances the β-amyloid-induced neuro-inflammatory response in microglia in Alzheimer’s disease
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Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease
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Nanotechnology-mediated crossing of two impermeable membranes to modulate the stars of the neurovascular unit for neuroprotection
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Macromolecular permeability across the blood-nerve and blood-brain barriers.
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Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines.
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Abnormal phosphorylation of tau and the mechanism of Alzheimer neurofibrillary degeneration: Sequestration of microtubule-associated proteins 1 and 2 and the disassembly of microtubules by the abnormal tau
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Amino-terminal Deletions Enhance Aggregation of β-Amyloid Peptides in Vitro
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The Serpin-Enzyme Complex Receptor Recognizes Soluble, Nontoxic Amyloid-β Peptide but Not Aggregated, Cytotoxic Amyloid-β Peptide
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Trans-cellular Propagation of Tau Aggregation by Fibrillar Species
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A CD36-initiated Signaling Cascade Mediates Inflammatory Effects of β-Amyloid
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Combined treatment with the phenolics (−)-epigallocatechin-3-gallate and ferulic acid improves cognition and reduces Alzheimer-like pathology in mice
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Occludin: a novel integral membrane protein localizing at tight junctions.
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Direct Binding of Three Tight Junction-Associated Maguks, Zo-1, Zo-2, and Zo-3, with the Cooh Termini of Claudins
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Amyloid beta oligomers induce impairment of neuronal insulin receptors
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Association of Vascular Amyloid β and Cells of the Mononuclear Phagocyte System in Hereditary Cerebral Hemorrhage with Amyloidosis (Dutch) and Alzheimer Disease
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Effects of oxidized and reduced forms of methylthioninium in two transgenic mouse tauopathy models
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PF-04494700, an Oral Inhibitor of Receptor for Advanced Glycation End Products (RAGE), in Alzheimer Disease
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Neurovascular Dysfunction and Faulty Amyloid -Peptide Clearance in Alzheimer Disease
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The neurovascular unit - concept review
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Calcium channel blockers and dementia
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Lenti‐GDNF Gene Therapy Protects Against Alzheimer's Disease‐Like Neuropathology in 3xTg‐AD Mice and MC65 Cells
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Review: Sporadic cerebral amyloid angiopathy
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Hereditary cerebral hemorrhage with amyloidosis‐Dutch type
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A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia
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Microglial C5aR (CD88) expression correlates with amyloid‐β deposition in murine models of Alzheimer’s disease
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Passive immunization targeting pathological phospho‐tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain
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Overview and introduction: The blood–brain barrier in health and disease
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ANAKINRA: THE FIRST INTERLEUKIN‐1 INHIBITOR IN THE TREATMENT OF RHEUMATOID ARTHRITIS
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Tau Protein and the Neurofibrillary Pathology of Alzheimer's Disease
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MDR1‐P‐Glycoprotein (ABCB1) Mediates Transport of Alzheimer’s Amyloid‐β Peptides—Implications for the Mechanisms of Aβ Clearance at the Blood–Brain Barrier
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Neuroinflammation: the devil is in the details
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The Blood-Brain Barrier/Neurovascular Unit in Health and Disease
inferredcites →https://doi.org/10.1126/science.1197623openalex-snapshot
Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease
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New Insights into Neuron-Glia Communication
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Glymphatic failure as a final common pathway to dementia
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Perivascular nerves and the regulation of cerebrovascular tone
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Astrocytes Function in Matching Blood Flow to Metabolic Activity
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Claudins and the Modulation of Tight Junction Permeability
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Endothelial Cell-to-Cell Junctions: Molecular Organization and Role in Vascular Homeostasis
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Current Research Therapeutic Strategies for Alzheimer’s Disease Treatment
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The Blood-Brain Barrier and Cancer: Transporters, Treatment, and Trojan Horses
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Natalizumab: Targeting α4-Integrins in Multiple Sclerosis
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Neuroinflammation and Blood-Brain Barrier Changes in Capillary Amyloid Angiopathy
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A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease
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Ion channel networks in the control of cerebral blood flow
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Current and Future Treatments in Alzheimer Disease: An Update
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Advances in cerebral amyloid angiopathy imaging
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Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity
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Tramiprosate, a drug of potential interest for the treatment of Alzheimer's disease, promotes an abnormal aggregation of tau
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Immunotherapy for Alzheimer’s disease: hoops and hurdles
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First-in-man tau vaccine targeting structural determinants essential for pathological tau–tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheimer’s disease model
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First Administration of the Fc-Attenuated Anti-β Amyloid Antibody GSK933776 to Patients with Mild Alzheimer’s Disease: A Randomized, Placebo-Controlled Study
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Tonic Local Brain Blood Flow Control by Astrocytes Independent of Phasic Neurovascular Coupling
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Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor.
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Immunotherapy Targeting Pathological Tau Conformers in a Tangle Mouse Model Reduces Brain Pathology with Associated Functional Improvements
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CD14 and Toll-Like Receptors 2 and 4 Are Required for Fibrillar Aβ-Stimulated Microglial Activation
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A Nanomedicine Transports a Peptide Caspase-3 Inhibitor across the Blood–Brain Barrier and Provides Neuroprotection
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Are the Extracelluar Pathways a Conduit for the Delivery of Therapeutics to the Brain?
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What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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HIF-1α downregulates the APP protein after oxygen and glucose deprivation in the APPswe/PSEN1 mouse model of Alzheimer's disease
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Astrocytic-derived vascular remodeling factors are independently associated with blood brain barrier permeability in Alzheimer’s disease
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Rhynchophylline Administration Ameliorates Amyloid-β Pathology and Inflammation in an Alzheimer’s Disease Transgenic Mouse Model
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Blocking α1 Adrenergic Receptor as a Novel Target for Treating Alzheimer’s Disease
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The vascular contribution of apolipoprotein E to Alzheimer’s disease
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A systematic review of normal tissue neurovascular unit damage following brain irradiation—Factors affecting damage severity and timing of effects
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Anatomy of a Setback: A Taxonomy of Clinical Trial Failures in Alzheimer's Disease and Strategic Lessons for the Future
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Pharmacologic Toll-like receptor 4 inhibition skews toward a favorable A1/A2 astrocytic ratio improving neurocognitive outcomes following traumatic brain injury
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Dynamics of brain-fluid circulation are altered in the mature-onset Tet-off APP mouse model of amyloidosis
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ACUTE AMYLOID-Β 40 EXPOSURE DISRUPTS METABOLIC INSULIN SIGNALING IN BLOOD-BRAIN BARRIER ENDOTHELIAL CELLS
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Advances and applications of fluids biomarkers in diagnosis and therapeutic targets of Alzheimer's disease
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Human hippocampal astrocytes: Computational dissection of their transcriptome, sexual differences and exosomes across ageing and mild‐cognitive impairment
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Choroidal Vascular Volume, White Matter Hyperintensity, and Their Interaction With Cognitive Function in Aging Adults
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Neurofilament Light Chain as a Biomarker of Global Cognition in Individuals With Possible Vascular Mild Cognitive Impairment
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Targeting Inflammation in Alzheimer’s Disease: Insights Into Pathophysiology and Therapeutic Avenues-A Comprehensive Review
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The Theoretical Intersection of Plant-Based Diets, Alzheimer’s, and Cardiovascular Disease
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The relationships between neuroglial alterations and neuronal changes in Alzheimer’s disease, and the related controversies I: Gliopathogenesis and glioprotection
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Identification of NDUFV2, NDUFS7, OPA1, and NDUFA1 as biomarkers for Alzheimer's disease: Insights from oxidative stress and mitochondrial dysfunction in the hippocampus
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Neuroinflammation and Alzheimer's disease: Unravelling the molecular mechanisms
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Biochemical modulators of synaptic plasticity: New horizons in Alzheimer's disease treatment
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Experience, challenges, and regional integration of the National Dementia Biobank (Mexico) and the National Brain Bank-UNPHU (Dominican Republic)
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Chronic effects of blast injury on the microvasculature in a transgenic mouse model of Alzheimer’s disease related Aβ amyloidosis
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Acute amyloid-β exposure disrupts insulin signaling in hCMEC/D3 blood–brain barrier endothelial cells
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Cell-specific transcriptional signatures of vascular cells in Alzheimer’s disease: perspectives, pathways, and therapeutic directions
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Altered dynamics of glymphatic flow in a mature-onset Tet-off APP mouse model of amyloidosis
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Machine learning models for dementia screening to classify brain amyloid positivity on positron emission tomography using blood markers and demographic characteristics: a retrospective observational study
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Neurovascular decoupling in cerebral small vessel disease-related gait disturbances in middle-aged and older adults: associations with blood biomarkers YKL-40 and neurofilament light chain
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Dysfunction of the neurovascular unit as a temporal driver in Alzheimer’s pathogenesis
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The importance of Vitamin-D and Neutrophil-Lymphocyte Ratio for Alzheimer’s Disease
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Identification and Correlation of Novel Genes Associated with Progression of Alzheimer’s Disease
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Dysfunction of the Blood-brain Barrier in Cerebral Microbleeds: from Bedside to Bench
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Endothelial Senescence in Neurological Diseases
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State of the Science on Brain Insulin Resistance and Cognitive Decline Due to Alzheimer’s Disease
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Frequency and spatial characteristics of EEG in patients with coronary artery disease with preserved cognitive status and cognitive disorders
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Kronik Böbrek Hastalığına Merkezi Sinir Sistemi Cevabı
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Developments in NEW triad research
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Peptide-Based Therapeutics for Alzheimer’s Disease: Medicinal Chemistry, AI-Guided Computational Design, and Blood–Brain Barrier Delivery
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Uncommon Noninvasive Biomarkers for the Evaluation and Monitoring of the Etiopathogenesis of Alzheimer's Disease
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Interactions between Beta-Amyloid and Pericytes in Alzheimer’s Disease
inferred← citeshttps://doi.org/10.31083/jin42796openalex-snapshot
Physiological Regulatory Mechanisms of Neurovascular Coupling and the Role of Its Dysfunction in Neurological Diseases
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Novel Serum Biomarkers of Neurovascular Unit Associated with Cortical Amyloid Deposition
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Protective Effect of Rivaroxaban Against Amyloid Pathology and Neuroinflammation Through Inhibiting PAR-1 and PAR-2 in Alzheimer’s Disease Mice
inferred← citeshttps://doi.org/10.3233/jad-221064openalex-snapshot
Microglia-Mediated Neurovascular Unit Dysfunction in Alzheimer’s Disease
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Retinal Functional and Structural Neural Indices: Potential Biomarkers for the Monitoring of Cerebral Neurodegeneration: The Maastricht Study
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The “Neuro-Glial-Vascular” Unit: The Role of Glia in Neurovascular Unit Formation and Dysfunction
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Multipath interaction network of annexin A2: multifaceted regulation and translational perspectives in neurological diseases
inferred← citeshttps://doi.org/10.3389/fnagi.2021.653334openalex-snapshot
Role of Neuron and Glia in Alzheimer’s Disease and Associated Vascular Dysfunction
inferred← citeshttps://doi.org/10.3389/fnagi.2021.749026openalex-snapshot
From Neurodevelopmental to Neurodegenerative Disorders: The Vascular Continuum
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Relationship Between Amyloid-β Deposition and Blood–Brain Barrier Dysfunction in Alzheimer’s Disease
inferred← citeshttps://doi.org/10.3389/fncel.2022.949412openalex-snapshot
Simple and efficient protocol to isolate and culture brain microvascular endothelial cells from newborn mice
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Perivascular spaces as a potential biomarker of Alzheimer’s disease
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Hypoxia-Induced Neuroinflammation in Alzheimer’s Disease: Potential Neuroprotective Effects of Centella asiatica
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Unraveling neurovascular mysteries: the role of endothelial glycocalyx dysfunction in Alzheimer’s disease pathogenesis
inferred← citeshttps://doi.org/10.3390/biology15141118openalex-snapshot
HIF1 Stabilization by Roxadustat Improves Cognition and Prevents Neuron Loss in Alzheimer’s Diseases In Vivo
inferred← citeshttps://doi.org/10.3390/biom11070980openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/biomedicines11030725openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/biomedicines11051411openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/brainsci13121624openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/brainsci16050434openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/cells11050813openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/cells12212531openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/ijms22073654openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/ijms23031134openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/ijms232415876openalex-snapshot
Molecular Mechanisms of Alzheimer’s Disease III
inferred← citeshttps://doi.org/10.3390/ijms24010078openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/ijms24043754openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/ijms24065383openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/ijms241210176openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/ijms26168066openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/ijms262411843openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/ijms27136066openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/ijms27167165openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/molecules27144463openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/ph17121741openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/pharmaceutics13111779openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/proteomes9030036openalex-snapshot
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Evidence for the Involvement of the Tachykinin NK1 Receptor in Acute Inflammation of the Central Nervous System
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Neurovascular unit permeability in neuroinflammatory diseases: a common pathologic and therapeutic target?
inferred← citeshttps://doi.org/10.4103/1673-5374.373672openalex-snapshot
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inferred← citeshttps://doi.org/10.4103/bc.bc_79_25openalex-snapshot
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inferred← citeshttps://doi.org/10.64898/2025.12.19.695574openalex-snapshot
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inferred← citeshttps://doi.org/10.64898/2026.03.04.26347509openalex-snapshot
Genetic liability to hip osteoarthritis confers neurovascular protection against Alzheimer’s disease despite depression-mediated phenotypic comorbidity
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Dysfunction of the neurovascular unit in brain aging
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