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Glycosylation Biomarkers Associated with Age-Related Diseases and Current Methods for Glycan Analysis

https://doi.org/10.3390/ijms22115788
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Functional Magnetic Resonance Imaging Methods
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Changes in Healthy Human IgG Fc-Glycosylation after Birth and during Early Childhood
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Glycosylation Changes in Serum Proteins Identify Patients with Pancreatic Cancer
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Comprehensive N-Glycome Profiling of Cells and Tissues for Breast Cancer Diagnosis
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Diagnostic and Prognostic Performance of Blood Plasma Glycan Features in the Women Epidemiology Lung Cancer (WELCA) Study
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Plasma Glycoprotein Profiling for Colorectal Cancer Biomarker Identification by Lectin Glycoarray and Lectin Blot
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GlycoSpectrumScan: Fishing Glycopeptides from MS Spectra of Protease Digests of Human Colostrum sIgA
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Glycomic Analysis of Sialic Acid Linkages in Glycans Derived from Blood Serum Glycoproteins
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Glycosylation of Immunoglobulin G Associates With Clinical Features of Inflammatory Bowel Diseases
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Plasma N-Glycan Signatures Are Associated With Features of Inflammatory Bowel Diseases
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Agalactosylated IgG antibodies depend on cellular Fc receptors for in vivo activity
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High Throughput Isolation and Glycosylation Analysis of IgG–Variability and Heritability of the IgG Glycome in Three Isolated Human Populations
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Specific Glycosylation of Membrane Proteins in Epithelial Ovarian Cancer Cell Lines: Glycan Structures Reflect Gene Expression and DNA Methylation Status
inferredcites →https://doi.org/10.1074/mcp.m113.037465openalex-snapshot
Comparative Performance of Four Methods for High-throughput Glycosylation Analysis of Immunoglobulin G in Genetic and Epidemiological Research
inferredcites →https://doi.org/10.1074/mcp.m116.065250openalex-snapshot
Human Plasma N-glycosylation as Analyzed by Matrix-Assisted Laser Desorption/Ionization-Fourier Transform Ion Cyclotron Resonance-MS Associates with Markers of Inflammation and Metabolic Health
inferredcites →https://doi.org/10.1074/mcp.m600171-mcp200openalex-snapshot
A Serum Glycomics Approach to Breast Cancer Biomarkers
inferredcites →https://doi.org/10.1074/mcp.r112.026310openalex-snapshot
Quantitative Glycomics Strategies
inferredcites →https://doi.org/10.1074/mcp.t600063-mcp200openalex-snapshot
Quantitative Glycomics of Human Whole Serum Glycoproteins Based on the Standardized Protocol for Liberating N-Glycans
inferredcites →https://doi.org/10.1080/08916934.2018.1468886openalex-snapshot
Glycosylation of random IgG distinguishes seropositive and seronegative rheumatoid arthritis
inferredcites →https://doi.org/10.1080/10409239891204198openalex-snapshot
Concepts and Principles of O-Linked Glycosylation
inferredcites →https://doi.org/10.1080/14789450.2018.1448710openalex-snapshot
Human disease glycomics: technology advances enabling protein glycosylation analysis – part 2
inferredcites →https://doi.org/10.1080/19420862.2016.1149662openalex-snapshot
The use of lectin microarray for assessing glycosylation of therapeutic proteins
inferredcites →https://doi.org/10.1089/omi.2016.0050openalex-snapshot
Glycan Biomarkers for Rheumatoid Arthritis and Its Remission Status in Han Chinese Patients
inferredcites →https://doi.org/10.1089/omi.2017.0044openalex-snapshot
Immunoglobulin G N -Glycans as Potential Postgenomic Biomarkers for Hypertension in the Kazakh Population
inferredcites →https://doi.org/10.1089/omi.2018.0053openalex-snapshot
Type 2 Diabetes Mellitus: Integrative Analysis of Multiomics Data for Biomarker Discovery
inferredcites →https://doi.org/10.1089/omi.2019.0075openalex-snapshot
Type 2 Diabetes Mellitus is Associated with the Immunoglobulin G N-Glycome through Putative Proinflammatory Mechanisms in an Australian Population
inferredcites →https://doi.org/10.1089/omi.2019.0099openalex-snapshot
Next-Generation (Glycomic) Biomarkers for Cardiometabolic Health: A Community-Based Study of Immunoglobulin G N -Glycans in a Chinese Han Population
inferredcites →https://doi.org/10.1089/rej.2007.0556openalex-snapshot
N-Glycomic Changes in Serum Proteins During Human Aging
inferredcites →https://doi.org/10.1093/ageing/afr084openalex-snapshot
Human serum N-glycan profiles are age and sex dependent
inferredcites →https://doi.org/10.1093/bioinformatics/btn090openalex-snapshot
GlycoBase and autoGU: tools for HPLC-based glycan analysis
inferredcites →https://doi.org/10.1093/gerona/glt190openalex-snapshot
Glycans Are a Novel Biomarker of Chronological and Biological Ages
inferredcites →https://doi.org/10.1093/glycob/cwl020openalex-snapshot
Gender-specific expression of complex-type N-glycans in schistosomes
inferredcites →https://doi.org/10.1093/glycob/cwl086openalex-snapshot
Comparison of the methods for profiling glycoprotein glycans—HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study
inferredcites →https://doi.org/10.1093/glycob/cwn095openalex-snapshot
A strategy to reveal potential glycan markers from serum glycoproteins associated with breast cancer progression
inferredcites →https://doi.org/10.1093/glycob/cwq188openalex-snapshot
EUROCarbDB: An open-access platform for glycoinformatics
inferredcites →https://doi.org/10.1093/glycob/cwx022openalex-snapshot
The N-glycosylation of immunoglobulin G as a novel biomarker of Parkinson's disease
inferredcites →https://doi.org/10.1093/jb/mvn011openalex-snapshot
Biological Function of Fucosylation in Cancer Biology
inferredcites →https://doi.org/10.1093/nar/gkg099openalex-snapshot
GlycoSuiteDB: a curated relational database of glycoprotein glycan structures and their biological sources. 2003 update
inferredcites →https://doi.org/10.1093/nar/gkh392openalex-snapshot
GlycoFragment and GlycoSearchMS: web tools to support the interpretation of mass spectra of complex carbohydrates
inferredcites →https://doi.org/10.1097/md.0000000000003379openalex-snapshot
The Association Between Glycosylation of Immunoglobulin G and Hypertension
inferredcites →https://doi.org/10.1097/md.0000000000004112openalex-snapshot
Profiling IgG N-glycans as potential biomarker of chronological and biological ages
inferredcites →https://doi.org/10.1097/mib.0000000000000372openalex-snapshot
Inflammatory Bowel Disease Associates with Proinflammatory Potential of the Immunoglobulin G Glycome
inferredcites →https://doi.org/10.1111/ane.12125openalex-snapshot
Immune system alterations in amyotrophic lateral sclerosis
inferredcites →https://doi.org/10.1111/j.1572-0241.2007.01699.xopenalex-snapshot
IgG Oligosaccharide Alterations Are a Novel Diagnostic Marker for Disease Activity and the Clinical Course of Inflammatory Bowel Disease
inferredcites →https://doi.org/10.1111/j.1742-4658.2009.07429.xopenalex-snapshot
Mucin‐type O‐glycosylation – putting the pieces together
inferredcites →https://doi.org/10.1126/science.1058890openalex-snapshot
Glycoprotein Structure Determination by Mass Spectrometry
inferredcites →https://doi.org/10.1126/science.1172539openalex-snapshot
Extending Healthy Life Span—From Yeast to Humans
inferredcites →https://doi.org/10.1126/science.1235681openalex-snapshot
Emerging Principles for the Therapeutic Exploitation of Glycosylation
inferredcites →https://doi.org/10.1134/s0006297913070031openalex-snapshot
Mass spectrometry of glycans
inferredcites →https://doi.org/10.1146/annurev.immunol.25.022106.141702openalex-snapshot
The Impact of Glycosylation on the Biological Function and Structure of Human Immunoglobulins
inferredcites →https://doi.org/10.1155/2008/515318openalex-snapshot
Glycomic Approach for Potential Biomarkers on Prostate Cancer: Profiling of N‐Linked Glycans in Human Sera and pRNS Cell Lines
inferredcites →https://doi.org/10.1155/2015/712490openalex-snapshot
The Role of Posttranslational Protein Modifications in Rheumatological Diseases: Focus on Rheumatoid Arthritis
inferredcites →https://doi.org/10.1158/1078-0432.ccr-04-2211openalex-snapshot
β1,6-Branched Oligosaccharides Are Increased in Lymph Node Metastases and Predict Poor Outcome in Breast Carcinoma
inferredcites →https://doi.org/10.1161/01.atv.0000112379.88385.67openalex-snapshot
Clinical Management of Metabolic Syndrome
inferredcites →https://doi.org/10.1161/01.cir.0000129535.04194.38openalex-snapshot
Inflammation as a Cardiovascular Risk Factor
inferredcites →https://doi.org/10.1161/circresaha.111.246876openalex-snapshot
The Intersection Between Aging and Cardiovascular Disease
inferredcites →https://doi.org/10.1161/circresaha.117.312174openalex-snapshot
Glycosylation Profile of Immunoglobulin G Is Cross-Sectionally Associated With Cardiovascular Disease Risk Score and Subclinical Atherosclerosis in Two Independent Cohorts
inferredcites →https://doi.org/10.1161/circulationaha.105.539528openalex-snapshot
Metabolic Syndrome as a Precursor of Cardiovascular Disease and Type 2 Diabetes Mellitus
inferredcites →https://doi.org/10.1172/jci114671openalex-snapshot
Neonatal plasminogen displays altered cell surface binding and activation kinetics. Correlation with increased glycosylation of the protein.
inferredcites →https://doi.org/10.1186/1471-2105-9-384openalex-snapshot
GlycomeDB – integration of open-access carbohydrate structure databases
inferredcites →https://doi.org/10.1186/1559-0275-11-15openalex-snapshot
Glycoproteomic and glycomic databases
inferredcites →https://doi.org/10.1186/s12933-014-0159-yopenalex-snapshot
Hypertriglyceridemia: a too long unfairly neglected major cardiovascular risk factor
inferredcites →https://doi.org/10.1186/s12967-018-1616-2openalex-snapshot
The changes of immunoglobulin G N-glycosylation in blood lipids and dyslipidaemia
showing the first 200 of 220

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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A Novel Insight Into the Etiology of Haff Disease by Mapping N-Glycome With Orthogonal Mass Spectrometry
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High‐Throughput N ‐Glycan Analysis by IR‐MALDESI With a 1.5‐kHz Pulsed Mid‐IR Laser
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Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022
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Recent Advances in Labeling‐Based Quantitative Glycomics: From High‐Throughput Quantification to Structural Elucidation
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Omega-3 Fatty Acids and Ageing Brain
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Salivary protein macromolecules as diagnostic and therapeutic biomarkers linking oral health and neurodegenerative diseases-emerging mechanisms and future perspectives
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Effects of testosterone and metformin on the GlycanAge index of biological age and the composition of the IgG glycome
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From Sequence Analysis to Application
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Glycosylation and its research progress in endometrial cancer
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Establishment of reference intervals for serum immunoglobulin G N-glycosylation features in healthy Chinese adults: a nationwide survey in the framework of predictive, preventive, and personalized medicine
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Recent omics advances in hair aging biology and hair biomarkers analysis
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Biomarkers of aging in frailty and age-associated disorders: State of the art and future perspective
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Caenorhabditis elegans as a potential model organism for studying the function of glycosylation in aging-related diseases
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Exploring glycobiomarkers beyond senescence-associated β-galactosidase for studying aging in vitro
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Novel Insight into the Etiology of Haff Disease by Mapping the N-Glycome with Orthogonal Mass Spectrometry
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Panax ginseng and aging related disorders: A systematic review
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Dietary glycans and their role in human health: implications for gut health, metabolism, and functional foods
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Selective editing of N-glycan signals on living cell surface
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Deep learning enhanced the diagnostic merit of serum glycome for multiple cancers
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Haptoglobin polymorphism affects its N-glycosylation pattern in serum
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Hair growth-promoting effects of Sargassum glaucescens oligosaccharides extracts
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Glycoproteoforms of Osteoarthritis-associated Lubricin in Plasma and Synovial Fluid
inferred← citeshttps://doi.org/10.1016/j.phymed.2025.156673openalex-snapshot
New insights into phytochemicals via protein glycosylation focused on aging and diabetes
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Exploration of biomarkers for inhibitor development in persons with hemophilia A
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High-throughput N-glycan analysis in aging and inflammaging: State of the art and future directions
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Characterization of Blood DNA Methylation Changes in a Murine Model of Prediabetes Induced by Fructose and Its Reversal
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Identification of genes associated with longevity in dogs: 9 candidate genes described in Cavalier King Charles Spaniel
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High-Resolution N-Glycan MALDI Mass Spectrometry Imaging of Subchondral Bone Tissue Microarrays in Patients with Knee Osteoarthritis
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The “Glyco-Remodeling” Hypothesis in Alzheimer’s Disease: Linking Protein N -Glycosylation to Pathogenesis and Translation
inferred← citeshttps://doi.org/10.1038/s41467-022-32867-zopenalex-snapshot
Circulating multimeric immune complexes contribute to immunopathology in COVID-19
inferred← citeshttps://doi.org/10.1038/s41467-023-44211-0openalex-snapshot
IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition
inferred← citeshttps://doi.org/10.1038/s41467-025-56249-3openalex-snapshot
Compositional data analysis enables statistical rigor in comparative glycomics
inferred← citeshttps://doi.org/10.1038/s41514-025-00254-9openalex-snapshot
A 2-year calorie restriction intervention may reduce glycomic biological age biomarkers – a pilot study
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Glycosylation changes of vWF in circulating extracellular vesicles to predict depression
inferred← citeshttps://doi.org/10.1080/00365513.2023.2230550openalex-snapshot
Galactosylation of serum immunoglobulin G in myasthenia gravis with different autoantibodies
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Breast cancer glycan biomarkers: their link to tumour cell metabolism and their perspectives in clinical practice
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The connections of sialic acids and diabetes mellitus: therapeutic or diagnostic value?
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Decoding Glycosylation in Neurodegenerative Diseases: Mechanistic Insights and Therapeutic Opportunities
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A Novel Fluorescent Immuno-Lectin Assay to Identify Osteoarthritis Associated Glycoforms of Lubricin
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The genetics and epidemiology of N- and O- IgA glycomics
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Ratios in Disguise, Truths Arise: Glycomics Meets Compositional Data Analysis
inferred← citeshttps://doi.org/10.1101/2024.12.04.24318451openalex-snapshot
A 2-year calorie restriction intervention reduces glycomic biological age biomarkers
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Integrative Machine Learning Approach to Explore Glycosylation Signatures and Immune Landscape in Moyamoya Disease
inferred← citeshttps://doi.org/10.1186/s13062-025-00609-yopenalex-snapshot
Plasma N-Glycoproteomics in monozygotic twin pairs discordant for body mass index reveals an obesity signature related to inflammation and iron metabolism
inferred← citeshttps://doi.org/10.1186/s13073-024-01369-6openalex-snapshot
The genetics and epidemiology of N- and O-immunoglobulin A glycomics
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Implications of aberrant glycosylation on age-related disease progression
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Glycan Profile Alterations in Vaginitis and Their Role in Pathogen-Host Interactions.
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Glycosylation-related molecular subtypes and risk score of hepatocellular carcinoma: Novel insights to clinical decision-making
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Impact of estrogen on IgG glycosylation and serum protein glycosylation in a murine model of healthy postmenopause
inferred← citeshttps://doi.org/10.3389/fimmu.2022.995186openalex-snapshot
Effects of low-calorie and different weight-maintenance diets on IgG glycome composition
inferred← citeshttps://doi.org/10.3389/fphar.2025.1570158openalex-snapshot
Decoding glycosylation in cardiovascular diseases: mechanisms, biomarkers, and therapeutic opportunities
inferred← citeshttps://doi.org/10.3390/biomedicines10081805openalex-snapshot
Concerted Regulation of Glycosylation Factors Sustains Tissue Identity and Function
inferred← citeshttps://doi.org/10.3390/ijms25094917openalex-snapshot
Uncovering Forensic Evidence: A Path to Age Estimation through DNA Methylation
inferred← citeshttps://doi.org/10.3390/ijms26157266openalex-snapshot
Temporal and Sex-Dependent N-Glycosylation Dynamics in Rat Serum
inferred← citeshttps://doi.org/10.3390/ijms262311495openalex-snapshot
Quantitative Modeling of IgG N-Glycosylation Profiles from Population Data
inferred← citeshttps://doi.org/10.3390/ijms27010552openalex-snapshot
Differential Glycosylation Patterns in Parkinson’s Disease: Emphasis on Male-Specific Changes Identified via HILIC-LC-MS
inferred← citeshttps://doi.org/10.3390/physiologia4020009openalex-snapshot
Identification of Putative Causal Relationships between Blood-Based Biomarkers and Prediabetes-Induced Senescence: A Comprehensive Review
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Glycosylation in aging and neurodegenerative diseases
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OTOİMMÜN HASTALIKLARDA GLİKAN BİYOBELİRTEÇLERİN KEŞFİ: TANI VE TEDAVİDE SON GELİŞMELER
inferred← citeshttps://doi.org/10.6084/m9.figshare.26531062openalex-snapshot
Additional file 1 of The genetics and epidemiology of N- and O-immunoglobulin A glycomics
inferred← citeshttps://doi.org/10.6084/m9.figshare.26531095openalex-snapshot
Additional file 2 of The genetics and epidemiology of N- and O-immunoglobulin A glycomics
inferred← citeshttps://doi.org/10.6084/m9.figshare.26758997openalex-snapshot
Additional file 3 of The genetics and epidemiology of N- and O-immunoglobulin A glycomics
inferred← citeshttps://doi.org/10.6084/m9.figshare.26759000openalex-snapshot
Additional file 4 of The genetics and epidemiology of N- and O-immunoglobulin A glycomics
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.