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TGF-β Signaling in Cancer: Mechanisms of Progression and Therapeutic Targets
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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TGF ‐β transactivates EGFR and facilitates breast cancer migration and invasion through canonical Smad3 and ERK /Sp1 signaling pathways
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Dual inhibition of TGF‐β and PD‐L1: a novel approach to cancer treatment
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S100A8 promotes epithelial‐mesenchymal transition and metastasis under TGF‐β/USF2 axis in colorectal cancer
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The tale of transforming growth factor‐beta (TGFβ) signaling: A soigné enigma
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TGF-β Signaling in Breast Cancer Cell Invasion and Bone Metastasis
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FGFs in Injury Repair and Regeneration
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Autophagy regulates transforming growth factor β signaling and receptor trafficking
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Lung cancer: Biology and treatment options
inferredcites →https://doi.org/10.1016/j.biopha.2020.111046openalex-snapshot
Recent progress in TGF-β inhibitors for cancer therapy
inferredcites →https://doi.org/10.1016/j.ccell.2018.03.002openalex-snapshot
The Platelet Lifeline to Cancer: Challenges and Opportunities
inferredcites →https://doi.org/10.1016/j.ccell.2020.12.001openalex-snapshot
Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer
inferredcites →https://doi.org/10.1016/j.ccell.2023.03.008openalex-snapshot
Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation
inferredcites →https://doi.org/10.1016/j.cellsig.2016.04.012openalex-snapshot
Reconstitution of TGFBR2 in HCT116 colorectal cancer cells causes increased LFNG expression and enhanced N-acetyl-d-glucosamine incorporation into Notch1
inferredcites →https://doi.org/10.1016/j.cmet.2018.04.022openalex-snapshot
Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer
inferredcites →https://doi.org/10.1016/j.gendis.2022.10.019openalex-snapshot
The role of TGF-β in the tumor microenvironment of pancreatic cancer
inferredcites →https://doi.org/10.1016/j.humpath.2016.07.007openalex-snapshot
PD-L1 expression is associated with epithelial-to-mesenchymal transition in adenocarcinoma of the lung
inferredcites →https://doi.org/10.1016/j.mcp.2023.101929openalex-snapshot
Current landscape of miRNAs and TGF‐β signaling in lung cancer progression and therapeutic targets
inferredcites →https://doi.org/10.1016/j.molcel.2019.09.030openalex-snapshot
Mechanisms Controlling PD-L1 Expression in Cancer
inferredcites →https://doi.org/10.1016/j.molonc.2015.04.016openalex-snapshot
Autophagy induction impairs migration and invasion by reversing EMT in glioblastoma cells
inferredcites →https://doi.org/10.1016/j.semnephrol.2013.11.009openalex-snapshot
Regulation of Autophagy by TGF-β: Emerging Role in Kidney Fibrosis
inferredcites →https://doi.org/10.1016/j.tcb.2018.12.001openalex-snapshot
EMT Transition States during Tumor Progression and Metastasis
inferredcites →https://doi.org/10.1016/j.trecan.2016.11.008openalex-snapshot
Targeting TGF-β Signaling in Cancer
inferredcites →https://doi.org/10.1038/cddis.2014.239openalex-snapshot
ΔNp63α activates CD82 metastasis suppressor to inhibit cancer cell invasion
inferredcites →https://doi.org/10.1038/cr.2008.328openalex-snapshot
Non-Smad pathways in TGF-β signaling
inferredcites →https://doi.org/10.1038/cr.2009.5openalex-snapshot
TGF-β-induced epithelial to mesenchymal transition
inferredcites →https://doi.org/10.1038/nature16064openalex-snapshot
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
inferredcites →https://doi.org/10.1038/nrc2853openalex-snapshot
TGFβ signalling: a complex web in cancer progression
inferredcites →https://doi.org/10.1038/nrneph.2016.48openalex-snapshot
TGF-β: the master regulator of fibrosis
inferredcites →https://doi.org/10.1038/s41418-021-00781-4openalex-snapshot
PLK1/vimentin signaling facilitates immune escape by recruiting Smad2/3 to PD-L1 promoter in metastatic lung adenocarcinoma
inferredcites →https://doi.org/10.1038/s41467-024-51442-2openalex-snapshot
The TGFβ type I receptor kinase inhibitor vactosertib in combination with pomalidomide in relapsed/refractory multiple myeloma: a phase 1b trial
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Platelets in cancer development and diagnosis
inferredcites →https://doi.org/10.1055/s-0034-1370765openalex-snapshot
NETosis: A New Factor in Tumor Progression and Cancer-Associated Thrombosis
inferredcites →https://doi.org/10.1080/13543784.2022.2152323openalex-snapshot
Next-generation immunotherapy for solid tumors: combination immunotherapy with crosstalk blockade of TGFβ and PD-1/PD-L1
inferredcites →https://doi.org/10.1093/annonc/mdw327openalex-snapshot
Prevention and screening in BRCA mutation carriers and other breast/ovarian hereditary cancer syndromes: ESMO Clinical Practice Guidelines for cancer prevention and screening
inferredcites →https://doi.org/10.1093/jnci/dju169openalex-snapshot
Therapeutic Targeting of Integrin αvβ6 in Breast Cancer
inferredcites →https://doi.org/10.1101/cshperspect.a022061openalex-snapshot
TGF-β Signaling from Receptors to Smads
inferredcites →https://doi.org/10.1101/cshperspect.a022129openalex-snapshot
Non-Smad Signaling Pathways of the TGF-β Family
inferredcites →https://doi.org/10.1101/gad.348226.120openalex-snapshot
Genetic and biological hallmarks of colorectal cancer
inferredcites →https://doi.org/10.1111/iwj.14075openalex-snapshot
The use of epidermal growth factor in dermatological practice
inferredcites →https://doi.org/10.1126/scisignal.2005304openalex-snapshot
TGF-β–induced epithelial-to-mesenchymal transition proceeds through stepwise activation of multiple feedback loops
inferredcites →https://doi.org/10.1126/scisignal.aav5183openalex-snapshot
Specificity, versatility, and control of TGF-β family signaling
inferredcites →https://doi.org/10.1136/jclinpath-2012-201078openalex-snapshot
Myoepithelial and epithelial–myoepithelial, mesenchymal and fibroepithelial breast lesions: updates from the WHO Classification of Tumours of the Breast 2012
inferredcites →https://doi.org/10.1146/annurev.immunol.24.021605.090737openalex-snapshot
TRANSFORMING GROWTH FACTOR-β REGULATION OF IMMUNE RESPONSES
inferredcites →https://doi.org/10.1155/2015/137823openalex-snapshot
Transforming Growth Factor Beta Family: Insight into the Role of Growth Factors in Regulation of Fracture Healing Biology and Potential Clinical Applications
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Tumor Cyclooxygenase-2/Prostaglandin E2–Dependent Promotion of FOXP3 Expression and CD4+CD25+ T Regulatory Cell Activities in Lung Cancer
inferredcites →https://doi.org/10.1158/1055-9965.epi-19-0221openalex-snapshot
Cancer Progress and Priorities: Lung Cancer
inferredcites →https://doi.org/10.1158/1078-0432.ccr-21-1504openalex-snapshot
First-In-Human Phase I Study of a Next-Generation, Oral, TGFβ Receptor 1 Inhibitor, LY3200882, in Patients with Advanced Cancer
inferredcites →https://doi.org/10.1159/000080763openalex-snapshot
Role of Insulin-Like Growth Factor Iin Maintaining Normal Glucose Homeostasis
inferredcites →https://doi.org/10.1161/circresaha.117.310795openalex-snapshot
Circulating Platelets as Mediators of Immunity, Inflammation, and Thrombosis
inferredcites →https://doi.org/10.1172/jci0215234openalex-snapshot
Blockade of TGF-β inhibits mammary tumor cell viability, migration, and metastases
inferredcites →https://doi.org/10.1172/jci15234openalex-snapshot
Blockade of TGF-β inhibits mammary tumor cell viability, migration, and metastases
inferredcites →https://doi.org/10.1172/jci65416openalex-snapshot
TGF-β inhibition enhances chemotherapy action against triple-negative breast cancer
inferredcites →https://doi.org/10.1172/jci67484openalex-snapshot
Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis
inferredcites →https://doi.org/10.1186/gb-2005-6-2-209openalex-snapshot
The vascular endothelial growth factor (VEGF) family: angiogenic factors in health and disease.
inferredcites →https://doi.org/10.1186/s12865-021-00434-8openalex-snapshot
Downregulation of NKG2DLs by TGF-β in human lung cancer cells
inferredcites →https://doi.org/10.1186/s12885-023-11153-1openalex-snapshot
A phase Ib/II study of galunisertib in combination with nivolumab in solid tumors and non-small cell lung cancer
inferredcites →https://doi.org/10.1186/s12943-022-01569-xopenalex-snapshot
Targeting TGF-β signal transduction for fibrosis and cancer therapy
inferredcites →https://doi.org/10.1186/s40425-018-0356-4openalex-snapshot
Targeting the TGFβ pathway with galunisertib, a TGFβRI small molecule inhibitor, promotes anti-tumor immunity leading to durable, complete responses, as monotherapy and in combination with checkpoint blockade
inferredcites →https://doi.org/10.1200/jco.2005.05.5335openalex-snapshot
Phase II Study of Belagenpumatucel-L, a Transforming Growth Factor Beta-2 Antisense Gene-Modified Allogeneic Tumor Cell Vaccine in Non–Small-Cell Lung Cancer
inferredcites →https://doi.org/10.1200/jco.2015.61.4743openalex-snapshot
Lobular Carcinoma in Situ: A 29-Year Longitudinal Experience Evaluating Clinicopathologic Features and Breast Cancer Risk
inferredcites →https://doi.org/10.1371/journal.pone.0090353openalex-snapshot
Phase I Study of GC1008 (Fresolimumab): A Human Anti-Transforming Growth Factor-Beta (TGFβ) Monoclonal Antibody in Patients with Advanced Malignant Melanoma or Renal Cell Carcinoma
inferredcites →https://doi.org/10.1371/journal.pone.0181579openalex-snapshot
β3 integrin expression is required for invadopodia-mediated ECM degradation in lung carcinoma cells
inferredcites →https://doi.org/10.18632/oncotarget.23795openalex-snapshot
Preclinical assessment of galunisertib (LY2157299 monohydrate), a first-in-class transforming growth factor-β receptor type I inhibitor
inferredcites →https://doi.org/10.21037/tcr.2019.02.09openalex-snapshot
Multiplex fluorescent immunohistochemistry quantitatively analyses microvascular density (MVD) and the roles of TGF-β signalling in orchestrating angiogenesis in colorectal cancer
inferredcites →https://doi.org/10.2147/ott.s493643openalex-snapshot
Exploring TGF-β Signaling in Cancer Progression: Prospects and Therapeutic Strategies
inferredcites →https://doi.org/10.2183/pjab.86.588openalex-snapshot
The discovery of Hepatocyte Growth Factor (HGF) and its significance for cell biology, life sciences and clinical medicine
inferredcites →https://doi.org/10.22088/ijmcm.bums.10.4.234openalex-snapshot
Regulation and Signaling of TGF-β Autoinduction.
inferredcites →https://doi.org/10.3389/fimmu.2015.00059openalex-snapshot
Macrophages at the Fork in the Road to Health or Disease
inferredcites →https://doi.org/10.3390/cells10061420openalex-snapshot
NKG2D Natural Killer Cell Receptor—A Short Description and Potential Clinical Applications
inferredcites →https://doi.org/10.3390/ijms19113466openalex-snapshot
The Roles of Autophagy in Cancer
inferredcites →https://doi.org/10.3390/ijms20235822openalex-snapshot
Transforming Growth Factor-β Signaling Pathway in Colorectal Cancer and Its Tumor Microenvironment
inferredcites →https://doi.org/10.3390/ijms21041193openalex-snapshot
MiRNAs and LncRNAs: Dual Roles in TGF-β Signaling-Regulated Metastasis in Lung Cancer
inferredcites →https://doi.org/10.3390/ijms232012346openalex-snapshot
Integrin Alpha v Beta 6 (αvβ6) and Its Implications in Cancer Treatment
inferredcites →https://doi.org/10.3390/medicina59091646openalex-snapshot
Colorectal Cancer: From Risk Factors to Oncogenesis
inferredcites →https://doi.org/10.5604/17322693.1068073openalex-snapshot
TGF-β signaling pathways in cancers
inferredcites →https://doi.org/10.5604/17322693.1086360openalex-snapshot
The role of vascular endothelial growth factor in inflammatory processes
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
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