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Development of a COX-2-Selective Fluorescent Probe for the Observation of Early Intervertebral Disc Degeneration

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/adhm.202102530openalex-snapshot

Intervertebral Disc Degeneration: Biomaterials and Tissue Engineering Strategies toward Precision Medicine

inferredcites →https://doi.org/10.1002/cyto.10026openalex-snapshot

Sequential immunofluorescence staining and image analysis for detection of large numbers of antigens in individual cell nuclei

inferredcites →https://doi.org/10.1002/jor.24028openalex-snapshot

Quantitative MRI correlates with histological grade in a percutaneous needle injury mouse model of disc degeneration

inferredcites →https://doi.org/10.1016/j.dyepig.2017.11.053openalex-snapshot

COX-2 targeting indomethacin conjugated fluorescent probe

inferredcites →https://doi.org/10.1016/j.joca.2020.09.002openalex-snapshot

The role of structure and function changes of sensory nervous system in intervertebral disc-related low back pain

inferredcites →https://doi.org/10.1016/j.snb.2020.129329openalex-snapshot

Development of two-photon fluorescence probe for detecting cyclooxygenase-2 level in human colorectal cancer tissue

inferredcites →https://doi.org/10.1016/j.tet.2012.05.127openalex-snapshot

New and efficient routes for the synthesis of murrayaquinone A and murrayanine

inferredcites →https://doi.org/10.1016/s0140-6736(20)32340-0openalex-snapshot

Global estimates of the need for rehabilitation based on the Global Burden of Disease study 2019: a systematic analysis for the Global Burden of Disease Study 2019

inferredcites →https://doi.org/10.1021/ac501944yopenalex-snapshot

Highly Sensitive Naphthalene-Based Two-Photon Fluorescent Probe for in Situ Real-Time Bioimaging of Ultratrace Cyclooxygenase-2 in Living Biosystems

inferredcites →https://doi.org/10.1021/acschembio.1c00961openalex-snapshot

Discovery of a Redox-Activatable Chemical Probe for Detection of Cyclooxygenase-2 in Cells and Animals

inferredcites →https://doi.org/10.1021/j100678a001openalex-snapshot

Measurement of photoluminescence quantum yields. Review

inferredcites →https://doi.org/10.1021/ja4056905openalex-snapshot

An Off–On COX-2-Specific Fluorescent Probe: Targeting the Golgi Apparatus of Cancer Cells

inferredcites →https://doi.org/10.1021/ml400066aopenalex-snapshot

The 2′-Trifluoromethyl Analogue of Indomethacin Is a Potent and Selective COX-2 Inhibitor

inferredcites →https://doi.org/10.1038/s41413-019-0071-xopenalex-snapshot

Inhibition of cyclooxygenase-2 activity in subchondral bone modifies a subtype of osteoarthritis

inferredcites →https://doi.org/10.1038/s41413-020-00125-xopenalex-snapshot

Painful intervertebral disc degeneration and inflammation: from laboratory evidence to clinical interventions

inferredcites →https://doi.org/10.1038/s41423-019-0294-1openalex-snapshot

Cyclooxygenase-2 is critical for the propagation of β-amyloid protein and reducing the glycosylation of tau in Alzheimer’s disease

inferredcites →https://doi.org/10.1038/s41467-022-29606-9openalex-snapshot

Chemotherapy-induced COX-2 upregulation by cancer cells defines their inflammatory properties and limits the efficacy of chemoimmunotherapy combinations

inferredcites →https://doi.org/10.1038/s41598-017-09528-zopenalex-snapshot

Cyclooxygenase-2 contributes to oxidopamine-mediated neuronal inflammation and injury via the prostaglandin E2 receptor EP2 subtype

inferredcites →https://doi.org/10.1038/s41598-017-17289-yopenalex-snapshot

A selective inhibition of c-Fos/activator protein-1 as a potential therapeutic target for intervertebral disc degeneration and associated pain

inferredcites →https://doi.org/10.1038/srep22573openalex-snapshot

Inhibition of cyclooxygenase-2 by NS398 attenuates noise-induced hearing loss in mice

inferredcites →https://doi.org/10.1039/c4cc08915dopenalex-snapshot

A Nile blue based infrared fluorescent probe: imaging tumors that over-express cyclooxygenase-2

inferredcites →https://doi.org/10.1073/pnas.97.2.925openalex-snapshot

Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: Facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors

inferredcites →https://doi.org/10.1111/j.1582-4934.2008.00430.xopenalex-snapshot

Cyclooxygenase in normal human tissues – is COX‐1 really a constitutive isoform, and COX‐2 an inducible isoform?

inferredcites →https://doi.org/10.1155/2012/413913openalex-snapshot

Diagnostic Testing for Degenerative Disc Disease

inferredcites →https://doi.org/10.1155/2021/2933199openalex-snapshot

The Upregulation of COX2 in Human Degenerated Nucleus Pulposus: The Association of Inflammation with Intervertebral Disc Degeneration

inferredcites →https://doi.org/10.1155/2021/6640751openalex-snapshot

Follistatin‐Like 1 Attenuation Suppresses Intervertebral Disc Degeneration in Mice through Interacting with TNF‐α and Smad Signaling Pathway

inferredcites →https://doi.org/10.1186/ar629openalex-snapshot

Degeneration of the intervertebral disc.

inferredcites →https://doi.org/10.1186/s13075-018-1743-4openalex-snapshot

The inflammatory response in the regression of lumbar disc herniation

inferredcites →https://doi.org/10.14245/ns.2040050.025openalex-snapshot

Actions of Prostaglandins on Human Nucleus Pulposus Metabolism Inferred by Cyclooxygenase 2 Inhibition of Cytokine Activated Cells

inferredcites →https://doi.org/10.14245/ns.2040108.054openalex-snapshot

Moving Forward: Gene Therapy for Intervertebral Disc Degeneration

inferredcites →https://doi.org/10.14245/ns.2040628.314openalex-snapshot

A Comparison of Mortality and Morbidity Between Complex and Degenerative Spine Surgery in Prospectively Collected Data From 2,280 Procedures

inferredcites →https://doi.org/10.14245/ns.2142256.128openalex-snapshot

The Beneficial Effect of Early Surgical Decompression for Acute Spinal Cord Injury: Time Is Spine

inferredcites →https://doi.org/10.14245/ns.2244366.183openalex-snapshot

Extra Cellular Matrix Remodeling: An Adjunctive Target for Spinal Cord Injury and Intervertebral Disc Degeneration

inferredcites →https://doi.org/10.3390/ijms21197391openalex-snapshot

An Injectable Hyaluronan–Methylcellulose (HAMC) Hydrogel Combined with Wharton’s Jelly-Derived Mesenchymal Stromal Cells (WJ-MSCs) Promotes Degenerative Disc Repair

inferredcites →https://doi.org/10.3390/ijms22041579openalex-snapshot

Genetic Therapy for Intervertebral Disc Degeneration

inferredcites →https://doi.org/10.5455/medarh.2019.73.421-424openalex-snapshot

A Brief Review of the Degenerative Intervertebral Disc Disease

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4729580openalex-extracted

A Two-Channel Fluorescent Probe for Simultaneous Detection of Cysteine and Glutathione in Food and Living Cells

inferred← citeshttps://doi.org/10.1002/adma.202408678openalex-snapshot

Sequential Targeted Enzyme‐Instructed Self‐Assembly Supramolecular Nanofibers to Attenuate Intervertebral Disc Degeneration

inferred← citeshttps://doi.org/10.1016/j.bioactmat.2023.11.021openalex-snapshot

Progress in regulating inflammatory biomaterials for intervertebral disc regeneration

inferred← citeshttps://doi.org/10.1016/j.bonr.2024.101784openalex-snapshot

Seeing the unseen: The role of bioimaging techniques for the diagnostic interventions in intervertebral disc degeneration

inferred← citeshttps://doi.org/10.1016/j.saa.2024.125098openalex-snapshot

Simultaneous detection of cysteine and glutathione in food with a two-channel near-infrared fluorescent probe

inferred← citeshttps://doi.org/10.1016/j.saa.2025.126696openalex-snapshot

A near-infrared AIE probe targeting COX-2 for imaging of Cancer cells

inferred← citeshttps://doi.org/10.1021/acsabm.4c01323openalex-snapshot

pH-Activatable Molecular Probe for COX-2 Imaging in Human Oral Squamous Carcinoma Cells and Patient-Derived Tissues

inferred← citeshttps://doi.org/10.1186/s13287-025-04600-2openalex-snapshot

Enhanced disc regeneration through CRISPR/Cas9-mediated SOX9 and TGFβ1 coexpression in tonsil-derived mesenchymal stromal cells

inferred← citeshttps://doi.org/10.3390/ijms242216024openalex-snapshot

Enhanced Intervertebral Disc Repair via Genetically Engineered Mesenchymal Stem Cells with Tetracycline Regulatory System

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