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Uncovering the Bioactive Potential of a Cyanobacterial Natural Products Library Aided by Untargeted Metabolomics

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/978-3-642-82340-4_1openalex-snapshot
Liquid-Overlay Culture of Cellular Spheroids
inferredcites →https://doi.org/10.1007/s10811-017-1369-yopenalex-snapshot
Cyanobacterial diversity held in microbial biological resource centers as a biotechnological asset: the case study of the newly established LEGE culture collection
inferredcites →https://doi.org/10.1016/j.ejps.2021.105876openalex-snapshot
Generation and analysis of 3D cell culture models for drug discovery
inferredcites →https://doi.org/10.1016/j.toxicon.2019.12.159openalex-snapshot
Portoamides A and B are mitochondrial toxins and induce cytotoxicity on the proliferative cell layer of in vitro microtumours
inferredcites →https://doi.org/10.1016/j.watres.2021.117017openalex-snapshot
CyanoMetDB, a comprehensive public database of secondary metabolites from cyanobacteria
inferredcites →https://doi.org/10.1021/acs.jnatprod.0c00072openalex-snapshot
Chlorosphaerolactylates A–D: Natural Lactylates of Chlorinated Fatty Acids Isolated from the Cyanobacterium Sphaerospermopsis sp. LEGE 00249
inferredcites →https://doi.org/10.1021/acs.jnatprod.9b01285openalex-snapshot
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
inferredcites →https://doi.org/10.1021/acschembio.8b00389openalex-snapshot
NCI Program for Natural Product Discovery: A Publicly-Accessible Library of Natural Product Fractions for High-Throughput Screening
inferredcites →https://doi.org/10.1021/np2002226openalex-snapshot
Minutissamides A–D, Antiproliferative Cyclic Decapeptides from the Cultured Cyanobacterium Anabaena minutissima
inferredcites →https://doi.org/10.1038/s41467-018-06082-8openalex-snapshot
Dereplication of microbial metabolites through database search of mass spectra
inferredcites →https://doi.org/10.1038/s41592-020-0933-6openalex-snapshot
Feature-based molecular networking in the GNPS analysis environment
inferredcites →https://doi.org/10.1038/s41596-020-0317-5openalex-snapshot
Reproducible molecular networking of untargeted mass spectrometry data using GNPS
inferredcites →https://doi.org/10.1073/pnas.0914343107openalex-snapshot
Synergistic allelochemicals from a freshwater cyanobacterium
inferredcites →https://doi.org/10.1080/09670262.2016.1163738openalex-snapshot
A polyphasic approach for the taxonomy of cyanobacteria: principles and applications
inferredcites →https://doi.org/10.1093/bioinformatics/btl529openalex-snapshot
Interactive Tree Of Life (iTOL): an online tool for phylogenetic tree display and annotation
inferredcites →https://doi.org/10.1093/bioinformatics/btx582openalex-snapshot
Ms2lda.org: web-based topic modelling for substructure discovery in mass spectrometry
inferredcites →https://doi.org/10.1093/molbev/msw054openalex-snapshot
MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets
inferredcites →https://doi.org/10.1093/nar/22.22.4673openalex-snapshot
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
inferredcites →https://doi.org/10.1093/nar/gkab301openalex-snapshot
Interactive Tree Of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation
inferredcites →https://doi.org/10.1128/aem.06516-11openalex-snapshot
DECIPHER, a Search-Based Approach to Chimera Identification for 16S rRNA Sequences
inferredcites →https://doi.org/10.1128/aem.63.8.3327-3332.1997openalex-snapshot
PCR primers to amplify 16S rRNA genes from cyanobacteria
inferredcites →https://doi.org/10.1128/microbe.3.277.1openalex-snapshot
Giant Marine Cyanobacteria Produce Exciting Potential Pharmaceuticals
inferredcites →https://doi.org/10.1177/108705719900400206openalex-snapshot
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays
inferredcites →https://doi.org/10.1186/s13321-016-0174-yopenalex-snapshot
ClassyFire: automated chemical classification with a comprehensive, computable taxonomy
inferredcites →https://doi.org/10.1371/journal.pcbi.1006089openalex-snapshot
Propagating annotations of molecular networks using in silico fragmentation
inferredcites →https://doi.org/10.1371/journal.pone.0188817openalex-snapshot
Cytotoxicity of portoamides in human cancer cells and analysis of the molecular mechanisms of action
inferredcites →https://doi.org/10.2307/3668646openalex-snapshot
Molecular Diversity of Microcystis Strains (Cyanophyceae, Chroococcales) Based on 16S rDNA Sequences
inferredcites →https://doi.org/10.3389/fmicb.2019.00683openalex-snapshot
Actinobacteria Isolated From Laminaria ochroleuca: A Source of New Bioactive Compounds
inferredcites →https://doi.org/10.3389/fonc.2019.00224openalex-snapshot
Antiproliferative Effects of the Natural Oxadiazine Nocuolin A Are Associated With Impairment of Mitochondrial Oxidative Phosphorylation
inferredcites →https://doi.org/10.3390/biology10101061openalex-snapshot
Bioactive Metabolites Produced by Cyanobacteria for Growth Adaptation and Their Pharmacological Properties
inferredcites →https://doi.org/10.3390/md14090158openalex-snapshot
Hierridin B Isolated from a Marine Cyanobacterium Alters VDAC1, Mitochondrial Activity, and Cell Cycle Genes on HT-29 Colon Adenocarcinoma Cells
inferredcites →https://doi.org/10.3390/md17020111openalex-snapshot
A Multi-Bioassay Integrated Approach to Assess the Antifouling Potential of the Cyanobacterial Metabolites Portoamides
inferredcites →https://doi.org/10.3390/md17040229openalex-snapshot
Chlorophyll Derivatives from Marine Cyanobacteria with Lipid-Reducing Activities
inferredcites →https://doi.org/10.3390/md17060320openalex-snapshot
Natural Products from Cyanobacteria: Focus on Beneficial Activities
inferredcites →https://doi.org/10.3390/md18050257openalex-snapshot
Pheophorbide a: State of the Art
inferredcites →https://doi.org/10.3390/md18120643openalex-snapshot
Marine Compounds and Cancer: Updates 2020
inferredcites →https://doi.org/10.3390/md19050241openalex-snapshot
Cyanobacteria—From the Oceans to the Potential Biotechnological and Biomedical Applications
inferredcites →https://doi.org/10.3390/metabo9070144openalex-snapshot
MolNetEnhancer: Enhanced Molecular Networks by Integrating Metabolome Mining and Annotation Tools
inferredcites →https://doi.org/10.3390/molecules25092197openalex-snapshot
Marine Cyanobacteria: A Source of Lead Compounds and their Clinically-Relevant Molecular Targets

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.5281/zenodo.16950285zenodo-depositor-declared
BIOGUIDED-DISCOVERY OF NEW CYANOBACTERIAL SALICYL CAPPEDTHIAZOL(IN)E SIDEROPHORES
inferred← citeshttps://doi.org/10.5281/zenodo.16950376zenodo-depositor-declared
Discovery and isolation of new cyanobacterial salicyl capped-thiazol(in)e siderophores
inferred← citeshttps://doi.org/10.1002/cbdv.202402282openalex-snapshot
Identification of Metabolites From Halamphora Sp. and Its Correlation With Quorum Sensing Inhibitory Activity via UHPLC‐ESI‐MS/MS‐Based Metabolomics and Molecular Networking
inferred← citeshttps://doi.org/10.1002/cbdv.202501582openalex-snapshot
Amazonian Cyanobacteria as a Source of Bioactive Compounds With Antimicrobial and Cytotoxic Properties
inferred← citeshttps://doi.org/10.1007/978-3-031-41741-2_9openalex-snapshot
Microbial Metabolites Annotation by Mass Spectrometry-Based Metabolomics
inferred← citeshttps://doi.org/10.1016/j.algal.2024.103702openalex-snapshot
Harnessing Leptolyngbya for antiproliferative and antimicrobial metabolites through lens of modern techniques: A review
inferred← citeshttps://doi.org/10.1016/j.algal.2024.103703openalex-snapshot
Metabolite profiling and bioactivity assessment of cyanobacteria from the Azores reveals unique producers of cytotoxic and lipid reducing compounds
inferred← citeshttps://doi.org/10.1016/j.bioorg.2022.106208openalex-snapshot
Guaiane-type sesquiterpenoids with various ring skeletons from Daphne bholua uncovered by molecular networking and structural revisions of previously reported analogues
inferred← citeshttps://doi.org/10.1016/j.crmicr.2022.100174openalex-snapshot
Untargeted GC–MS reveals differential regulation of metabolic pathways in cyanobacterium Anabaena and its biofilms with Trichoderma viride and Providencia sp.
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e37851openalex-snapshot
Colombian cyanobacteria with cytotoxic activity in cancer cell lines
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.5c00204openalex-snapshot
Decoding Lusichelins A–E: An In-Depth Look at the Metallophores of Lusitaniella coriacea LEGE 07167–Structure, Production, and Functionality
inferred← citeshttps://doi.org/10.1038/s41598-023-40542-6openalex-snapshot
Bioprospecting for industrially relevant exopolysaccharide-producing cyanobacteria under Portuguese simulated climate
inferred← citeshttps://doi.org/10.1080/1040841x.2026.2655676openalex-snapshot
Recent advances in omics-driven research of photosynthetic microorganisms in green biotechnology
inferred← citeshttps://doi.org/10.3389/fmicb.2022.1075621openalex-snapshot
Comparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains
inferred← citeshttps://doi.org/10.3390/app12062847openalex-snapshot
A Novel Approach for Fast Screening of a Complex Cyanobacterial Extract for Immunomodulatory Properties and Antibacterial Activity
inferred← citeshttps://doi.org/10.3390/md20120761openalex-snapshot
Cosmetic Application of Cyanobacteria Extracts with a Sustainable Vision to Skincare: Role in the Antioxidant and Antiaging Process
inferred← citeshttps://doi.org/10.3390/md21060359openalex-snapshot
Cyanobacteria: A Promising Source of Antifungal Metabolites
inferred← citeshttps://doi.org/10.3390/md21080452openalex-snapshot
Marine Drug Discovery through Computer-Aided Approaches
inferred← citeshttps://doi.org/10.3390/md21090498openalex-snapshot
Metabolite Profile Characterization of Cyanobacterial Strains with Bioactivity on Lipid Metabolism Using In Vivo and In Vitro Approaches
inferred← citeshttps://doi.org/10.3390/md22090412openalex-snapshot
Screening of Lipid-Reducing Activity and Cytotoxicity of the Exometabolome from Cyanobacteria
inferred← citeshttps://doi.org/10.3390/plants15010033openalex-snapshot
Cyanobacterial Biofactories Beyond Model Strains: Exploratory Screening of Immunomodulatory Activity in Phormidium ambiguum Extracts
inferred← citeshttps://doi.org/10.3390/s23031338openalex-snapshot
A Multiplex Molecular Cell-Based Sensor to Detect Ligands of PPARs: An Optimized Tool for Drug Discovery in Cyanobacteria
inferred← citeshttps://doi.org/10.3390/toxins14050330openalex-snapshot
Pseudanabaena galeata CCNP1313—Biological Activity and Peptides Production
inferred← citeshttps://doi.org/10.5802/crchim.250openalex-snapshot
Effects of Lagarosiphon major extracts on the metabolome and photosynthesis of Microcystis aeruginosa
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