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Biological Activities and Cytotoxicity of Diterpenes from Copaifera spp. Oleoresins

https://doi.org/10.3390/molecules20046194

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Medicinal Natural Products

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Ultraviolet radiation directly induces pigment production by cultured human melanocytes

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Phytochemical and antioedematogenic studies of commercial copaiba oils available in Brazil

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The Protease-Activated Receptor 2 Regulates Pigmentation via Keratinocyte-Melanocyte Interactions

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Cyclooxygenase, lipoxygenase and tumor angiogenesis

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Molecular insights to explore abietane diterpenes as new LOX inhibitors

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A molecular pharmacology study into the anti-inflammatory actions of Euphorbia hirta L. on the LPS-induced RAW 264.7 cells through selective iNOS protein inhibition

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Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

inferredcites →https://doi.org/10.1016/j.bbrc.2008.02.002openalex-snapshot

Dehydroabietic acid, a phytochemical, acts as ligand for PPARs in macrophages and adipocytes to regulate inflammation

inferredcites →https://doi.org/10.1016/j.bbrc.2008.02.104openalex-snapshot

Modulation of inflammatory responses by diterpene acids from Helianthus annuus L.

inferredcites →https://doi.org/10.1016/j.ejmech.2010.06.029openalex-snapshot

Synthesis and biological evaluation of (+)-labdadienedial, derivatives and precursors from (+)-sclareolide

inferredcites →https://doi.org/10.1016/j.foreco.2010.10.014openalex-snapshot

Determinants of yield in a non-timber forest product: Copaifera oleoresin in Amazonian extractive reserves

inferredcites →https://doi.org/10.1016/j.ijpharm.2012.08.021openalex-snapshot

GC–MS profiling of the phytochemical constituents of the oleoresin from Copaifera langsdorffii Desf. and a preliminary in vivo evaluation of its antipsoriatic effect

inferredcites →https://doi.org/10.1016/j.jep.2007.03.005openalex-snapshot

Chemical composition and anti-inflammatory activity of copaiba oils from Copaifera cearensis Huber ex Ducke, Copaifera reticulata Ducke and Copaifera multijuga Hayne—A comparative study

inferredcites →https://doi.org/10.1016/j.taap.2007.12.006openalex-snapshot

Supression of inflammatory responses by labdane-type diterpenoids

inferredcites →https://doi.org/10.1016/s0006-291x(03)00751-4openalex-snapshot

Tyrosinase protects human melanocytes from ROS-generating compounds

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Assessment of the Alamar Blue assay for cellular growth and viability in vitro

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The cytotoxic and embryotoxic effects of kaurenoic acid, a diterpene isolated from Copaifera langsdorffii oleo-resin

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The isolation and in vivo Potent Antitumor activity of clerodane diterpenoid from the oleoresin of the brazilian medicinal plant, copaifera langsdorfi desfon.

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Synthesis of a novel family of diterpenes and their evaluation as anti-inflammatory agents

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Antioxidant Activity of Dodecyl Gallate

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Inhibition of Diphenolase Activity of Tyrosinase by Vitamin B6 Compounds

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Lipoxygenase Inhibitory Activity of Anacardic Acids

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Rapid chromatographic technique for preparative separations with moderate resolution

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Lipoxygenase Inhibitory Constituents fromPeriplocaaphylla

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Antityrosinase and Antioxidant Effects of ent-Kaurane Diterpenes from Leaves of Broussonetia papyrifera

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Tyrosinases from crustaceans form hexamers

inferredcites →https://doi.org/10.1055/s-2006-960122openalex-snapshot

Cytotoxic Clerodane Diterpenes fromPolyalthia longifolia

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Inhibition of the Nuclear Factor κB (NF-κB) Pathway by Tetracyclic Kaurene Diterpenes in Macrophages

inferredcites →https://doi.org/10.1080/10236240902765301openalex-snapshot

Cytotoxic clerodane diterpenoids from the leaves ofPolyalthia longifolia

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Inhibition of skin pigmentation by an extract of Lepidium apetalum and its possible implication in IL‐6 mediated signaling

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The inhibition of paw oedema formation caused by the oil of Copaifera multijuga Hayne and its fractions

inferredcites →https://doi.org/10.1155/2013/735176openalex-snapshot

Inhibition of Inflammatory Response by Artepillin C in Activated RAW264.7 Macrophages

inferredcites →https://doi.org/10.1155/2013/761323openalex-snapshot

Trans - β -Caryophyllene: An Effective Antileishmanial Compound Found in Commercial Copaiba Oil ( Copaifera spp.)

inferredcites →https://doi.org/10.1182/blood-2003-04-1228openalex-snapshot

IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF-α production in macrophages

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Interleukin-6 and chronic inflammation.

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A Novel Labdane-Type Trialdehyde from Myoga (Zingiber miogaRoscoe) That Potently Inhibits Human Platelet Aggregation and Human 5-Lipoxygenase

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Mecanismos de ação de compostos bioativos dos alimentos no contexto de processos inflamatórios relacionados à obesidade

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Controle de autenticidade de óleos de copaíba comerciais por cromatografia gasosa de alta resolução

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O gênero copaifera L.

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Efeito do óleo de copaíba nos níveis séricos de uréia e creatinina em ratos submetidos à síndrome de isquemia e reperfusão renal

inferredcites →https://doi.org/10.1590/s1984-82502010000200024openalex-snapshot

In vitro evaluation of copaiba oil as a kojic acid skin enhancer

inferredcites →https://doi.org/10.2307/4114524openalex-snapshot

Medicinal Natural Products: A Biosynthetic Approach

inferredcites →https://doi.org/10.3390/molecules17043866openalex-snapshot

Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins

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Terpenoids and Unusual Flavonoids Bearing Prenylated Malonic Acids in Dodonaea Species

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Production of More Potent Anti‐Candida Labdane Diterpenes by Biotransformation Using Cunninghamella elegans

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Molecular distillation of copaiba oleoresin—A clean process for diterpenes enrichment

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Copalic Acid: Occurrence, Chemistry, and Biological Activities

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Kaurenoic Acid

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Copaifera langsdorffii Desf.: A chemical and pharmacological review

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Trypanocidal activity of copaiba oil and kaurenoic acid does not depend on macrophage killing machinery

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Occurrence, chemical composition, biological activities and analytical methods on Copaifera genus—A review

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Plants from the Brazilian Traditional Medicine: species from the books of the Polish physician Piotr Czerniewicz (Pedro Luiz Napoleão Chernoviz, 1812–1881)

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Dehydroabietic acid isolated from Pinus elliottii exerts in vitro antileishmanial action by pro-oxidant effect, inducing ROS production in promastigote and downregulating Nrf2/ferritin expression in amastigote forms of Leishmania amazonensis

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Hexane extract of Pittosporopsis kerrii Craib mitigates LPS-driven inflammatory responses via JAK/STAT1 pathway inhibition in RAW 264.7 macrophages

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Chemical compositions and herbicidal (phytotoxic) activity of essential oils of three Copaifera species (Leguminosae-Caesalpinoideae) from Amazon-Brazil

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Kaurenoic acid nanocarriers regulates cytokine production and inhibit breast cancer cell migration

inferred← citeshttps://doi.org/10.1016/j.jep.2019.02.017openalex-snapshot

Acid diterpenes from Copaiba oleoresin (Copaifera langsdorffii): Chemical and plasma stability and intestinal permeability using Caco-2 cells

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Antinociceptive and anti-inﬂammatory activities of Copaifera pubiflora Benth oleoresin and its major metabolite ent-hardwickiic acid

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Labdane diterpenoids as potential anti-inflammatory agents

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Grandiflorenic acid promotes death of promastigotes via apoptosis-like mechanism and affects amastigotes by increasing total iron bound capacity

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The amide derivative of anticopalic acid induces non-apoptotic cell death in triple-negative breast cancer cells by inhibiting FAK activation

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UHPLC-HRMS/MS on untargeted metabolomics: a case study with Copaifera (Fabaceae)

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Origine et prédiction de la variabilité de la durabilité naturelle chez Dicorynia guianensis Amsh

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