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Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264.7 cells
Quercetin Inhibits Inflammatory Response Induced by LPS from Porphyromonas gingivalis in Human Gingival Fibroblasts via Suppressing NF- κ B Signaling Pathway
A Comparison of the Effects of Quercetin Hydrate With Those of Vitamin E on the Levels of IL-13, PDGF, TNF-α, and INF-γ in Bleomycin-Induced Pulmonary Fibrosis in Rats
Anti-Inflammatory Effects of Neochlorogenic Acid Extract from Mulberry Leaf (Morus alba L.) Against LPS-Stimulated Inflammatory Response through Mediating the AMPK/Nrf2 Signaling Pathway in A549 Cells
From small‐scale studies to an encompassing view: Inhibiting inflammation and clinically relevant enzymes with various extracts of Primula vulgaris using in vitro and in silico techniques
Camphene Mitigates Cyclophosphamide‐Induced Oxidative Stress, Neuroinflammation, and Cognitive Dysfunction via Nrf2, NF‐κB, and Astrocytic GFAP Modulation in Wistar Albino Rats
Immunomodulatory and locomotor regulations via Diosgenin treatment in lipopolysaccharide-induced chronic fatigue syndrome (CFS)/ depressive despair symptom: an in vivo assessment
Possible protective effect of quercetin on lung injury induced by skeletal muscle ischemia reperfusion (IR) injury of adult male albino rats: Histological and biochemical study
Downregulation of NOX2 Expression Alleviates Severe Acute Pancreatitis by Restoring Autophagy and Inhibiting mtDNA-mediated Activation of the cGAS-STING Signalling Pathway
Hibiscus sabdariffa L. (Roselle flower) extract exerts protective effects against lipopolysaccharide-induced inflammation by ameliorating TLR4/NF-κB and NLRP3 inflammasome activation
Lipopolysaccharide-Educated Cancer-Associated Fibroblasts Facilitate Malignant Progression of Ovarian Cancer Cells via the NF-kB/IL-6/JAK2 Signal Transduction
A Balanced Cannabinoids Mixture Protects Neural Stem/progenitor Cells from CoCl2 Induced Injury by Regulating Autophagy and Inflammation: An in Vitro Study
Targeting T2Rs, a feasible approach for natural bitter agents from traditional Chinese medicine modulate ABC transporters to treat respiratory diseases
Industrial-produced lemon nanovesicles ameliorate experimental colitis-associated damages in rats via the activation of anti-inflammatory and antioxidant responses and microbiota modification
Engineering injectable hyaluronic acid-based adhesive hydrogels with anchored PRP to pattern the micro-environment to accelerate diabetic wound healing
Lead exposure induced developmental nephrotoxicity in Japanese quail (Coturnix japonica) via oxidative stress-based PI3K/AKT pathway inhibition and NF-κB pathway activation
A biomimetic Trojan Horse inspired exosome-hydrogel-bone scaffold nested cascade delivery system: Modulating the "Don't Eat Me" signal for synergistic intracellular-targeted acid-responsive antibacterial therapy and bone regeneration
Polyphosphazene nanodrugs for targeting delivery and inflammation responsive release of curcumin to treat acute lung injury by effectively inhibiting cytokine storms
Synergistic efficacy of marigold-derived lutein, quercetin, and quercetagetin in alleviating dry eye disease: Mechanistic insights from in vitro and in vivo models
Elaidic acid induces testicular oxidative stress, inflammation, Wnt/β-catenin disruption and abnormalities in steroidogenesis, spermatogenesis and histo-architecture in Sprague Dawley rats
Anti-inflammatory mechanism of Achyranthes longifolia extract and its component chikusetsusaponin IVa by modulating Nrf2/NF-κB pathways in vitro and in vivo
Lacticaseibacillus rhamnosus 1.0320 isolated from fermented kumis combined with 3-Fucosyllactose and 3′-Sialyllactose ameliorates LPS-induced intestinal epithelial barrier dysfunction by inhibiting the NF-κB pathway and activating the Nrf2 pathway
5H Pyrolo(3,4-b)Pyrazin-5,7-(6H)-dione 6-(N-Chitosanimide nanoparticle) composite nano silver and encapsulation in γ-cyclodextrin: Synthesis, molecular docking, and biological evaluation for thyroid cancer treatment
Review of polysaccharides from Elaeagnus angustifolia: Extraction, purification, nutritional values, structural characteristics and biological activities
Assessing protective antioxidant and immunomodulatory actions of Isoberlinia tomentosa in a PFAS toxicity model: In-vivo outcomes and in-silico docking insights
Combined network pharmacology and experimental validation reveals the mechanism of Gentiana veitchiorum Hemsl. and its active ingredient in the treatment of acute lung injury
Underlying mechanisms of traditional Chinese medicine in the prevention and treatment of diabetic retinopathy: Evidences from molecular and clinical studies
Bioactivity of Talisia esculenta extracts: Antioxidant and anti-inflammatory action on RAW 264.7 macrophages and protective potential on the zebrafish exposed to oxidative stress inducers
The anti-inflammatory effects of paeonol from Cynanchum paniculatum extracts on LPS-induced macrophage RAW 264.7 cells and Helicobacter pylori-infected gastrointestinal mucosal damaged zebrafish
Investigating the pharmacodynamic mechanism of Erxian decoction to alleviate sarcopenia generated by ovarian aging through the ER-mediated estrogen signaling pathway
Integrated network pharmacology and transcriptomics analysis elucidated the underlying mechanisms by which Pegaeophyton scapiflorum alleviated LPS-induced acute lung injury
Curcumin-encapsulated exosomes in bisphosphonate-modified hydrogel microspheres promote bone repair through macrophage polarization and DNA damage mitigation
Ameliorative role of catechin to combat against lindane instigated liver toxicity via modulating PI3K/PIP3/Akt, Nrf-2/Keap-1, NF-κB pathway and histological profile
Rhizoma Alismatis Decoction improved mitochondrial dysfunction to alleviate SASP by enhancing autophagy flux and apoptosis in hyperlipidemia acute pancreatitis
Ursolic acid attenuates LPS-induced cognitive dysfunction through the modulation of oxidative stress, neuroinflammation, and hippocampal synaptic plasticity
Mechanisms of exacerbation of Th2-mediated eosinophilic allergic asthma induced by plastic pollution derivatives (PPD): A molecular toxicological study involving lung cell ferroptosis and metabolomics
Quercetin inhibits the NOX2/ROS-mediated NF-κB/TXNIP signaling pathway to ameliorate pyroptosis of cardiomyocytes to relieve sepsis-induced cardiomyopathy
Thioacetamide-induced hepatotoxicity in rats: Hepatoprotective role of ethyl gallate in association with the regulation of Nrf2/MAPK/NF-κB signaling pathway
Unravelling the potential of Vitex negundo leaf extract in LPS-induced acute lung injury in mice through modulation of the TLR-4/NF-κB p65/iNOS pathway: Insights from integrated phytochemical characterization, in silico, and in vivo analysis
Remote Ischemic Conditioning Relieves Necrotizing Enterocolitis Through Regulation of Redox and Inflammation
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