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How the Structure of Per- and Polyfluoroalkyl Substances (PFAS) Influences Their Binding Potency to the Peroxisome Proliferator-Activated and Thyroid Hormone Receptors—An In Silico Screening Study

https://doi.org/10.3390/molecules28020479
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Perfluoroalkyl Substances (PFAS) and Their Effects on the Placenta, Pregnancy, and Child Development: a Potential Mechanistic Role for Placental Peroxisome Proliferator–Activated Receptors (PPARs)
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The new generation PFAS C6O4 does not produce adverse effects on thyroid cells in vitro
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The PFAS-Tox Database: A systematic evidence map of health studies on 29 per- and polyfluoroalkyl substances
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Using Machine Learning to Classify Bioactivity for 3486 Per- and Polyfluoroalkyl Substances (PFASs) from the OECD List
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Structure-Based Investigation on the Interaction of Perfluorinated Compounds with Human Liver Fatty Acid Binding Protein
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inferredcites →https://doi.org/10.1093/toxsci/kfh130openalex-snapshot
trans-Activation of PPAR and Induction of PPAR Target Genes by Perfluorooctane-Based Chemicals
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inferredcites →https://doi.org/10.1093/toxsci/kfl135openalex-snapshot
Activation of Mouse and Human Peroxisome Proliferator–Activated Receptors (α, β/δ, γ) by Perfluorooctanoic Acid and Perfluorooctane Sulfonate
inferredcites →https://doi.org/10.1093/toxsci/kfn166openalex-snapshot
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Per- and Polyfluoroalkyl Substances and Alternatives in Coatings, Paints and Varnishes (CPVs): Report on the Commercial Availability and Current Uses
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What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Analysis of transcriptomic alterations induced by 33 different per- and polyfluoroalkyl substances (PFAS) in differentiated HepaRG cells
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Myclobutanil induces cardiovascular toxicity via thyroid disruption in zebrafish larvae
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Impact of understudied PFAS on Lipid Metabolism in Hepatocyte 2D and 3D in vitro model
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Effects of Chemical Speciation on Chronic Thyroid Toxicity of Representative Perfluoroalkyl Acids
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Binding of Per- and Polyfluoroalkyl Substances (PFAS) to the PPARγ/RXRα–DNA Complex
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PPARs, L-FABP mediate the association between Per- and polyfluoroalkyl substances and gestational diabetes: a nested case-control study
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