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Flavonoids as Anticancer Agents
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/cam4.1411openalex-snapshotQuercetin as an innovative therapeutic tool for cancer chemoprevention: Molecular mechanisms and implications in human health
inferredcites →https://doi.org/10.1002/jcb.25729openalex-snapshotNaringenin‐Induced Apoptotic Cell Death in Prostate Cancer Cells Is Mediated via the PI3K/AKT and MAPK Signaling Pathways
inferredcites →https://doi.org/10.1002/jcp.24818openalex-snapshotHesperetin Induces Apoptosis in Breast Carcinoma by Triggering Accumulation of ROS and Activation of ASK1/JNK Pathway
inferredcites →https://doi.org/10.1002/jcp.26150openalex-snapshotChrysin attenuates progression of ovarian cancer cells by regulating signaling cascades and mitochondrial dysfunction
inferredcites →https://doi.org/10.1002/mc.20866openalex-snapshotPlant flavone apigenin inhibits HDAC and remodels chromatin to induce growth arrest and apoptosis in human prostate cancer cells: In vitro and in vivo study
inferredcites →https://doi.org/10.1002/ptr.2815openalex-snapshotThe effect of crataegus fruit extract and some of its flavonoids on mitochondrial oxidative phosphorylation in the heart
inferredcites →https://doi.org/10.1002/ptr.6227openalex-snapshotChemo‐preventive and therapeutic effect of the dietary flavonoid kaempferol: A comprehensive review
inferredcites →https://doi.org/10.1007/s10753-016-0311-9openalex-snapshotHesperetin Suppresses Inflammatory Responses in Lipopolysaccharide-Induced RAW 264.7 Cells via the Inhibition of NF-κB and Activation of Nrf2/HO-1 Pathways
inferredcites →https://doi.org/10.1007/s12032-015-0516-zopenalex-snapshotHesperetin induces the apoptosis of hepatocellular carcinoma cells via mitochondrial pathway mediated by the increased intracellular reactive oxygen species, ATP and calcium
inferredcites →https://doi.org/10.1007/s12272-010-0808-yopenalex-snapshotQuercetin-mediated cell cycle arrest and apoptosis involving activation of a caspase cascade through the mitochondrial pathway in human breast cancer MCF-7 cells
inferredcites →https://doi.org/10.1007/s13277-015-4176-6openalex-snapshotHesperetin induces apoptosis of esophageal cancer cells via mitochondrial pathway mediated by the increased intracellular reactive oxygen species
inferredcites →https://doi.org/10.1007/s13277-016-5013-2openalex-snapshotNaringenin inhibits proliferation, migration, and invasion as well as induces apoptosis of gastric cancer SGC7901 cell line by downregulation of AKT pathway
inferredcites →https://doi.org/10.1016/j.bbadis.2013.07.014openalex-snapshotNegative modulation of mitochondrial oxidative phosphorylation by epigallocatechin-3 gallate leads to growth arrest and apoptosis in human malignant pleural mesothelioma cells
inferredcites →https://doi.org/10.1016/j.bcp.2006.06.021openalex-snapshotSuppression of MyD88- and TRIF-dependent signaling pathways of toll-like receptor by (−)-epigallocatechin-3-gallate, a polyphenol component of green tea
inferredcites →https://doi.org/10.1016/j.biopha.2016.06.019openalex-snapshotProcyanidin-rich extract of natural cocoa powder causes ROS-mediated caspase-3 dependent apoptosis and reduction of pro-MMP-2 in epithelial ovarian carcinoma cell lines
inferredcites →https://doi.org/10.1016/j.fct.2011.11.038openalex-snapshotRole of hesperetin (a natural flavonoid) and its analogue on apoptosis in HT-29 human colon adenocarcinoma cell line – A comparative study
inferredcites →https://doi.org/10.1016/j.jnutbio.2008.10.009openalex-snapshotCocoa flavonoids up-regulate antioxidant enzyme activity via the ERK1/2 pathway to protect against oxidative stress-induced apoptosis in HepG2 cells
inferredcites →https://doi.org/10.1016/j.lfs.2019.117073openalex-snapshotGenistein potentiates Centchroman induced antineoplasticity in breast cancer via PI3K/Akt deactivation and ROS dependent induction of apoptosis
inferredcites →https://doi.org/10.1017/s0007114509991747openalex-snapshotEpicatechin induces NF-κB, activator protein-1 (AP-1) and nuclear transcription factor erythroid 2p45-related factor-2 (Nrf2) via phosphatidylinositol-3-kinase/protein kinase B (PI3K/AKT) and extracellular regulated kinase (ERK) signalling in HepG2 cells
inferredcites →https://doi.org/10.1021/acs.jafc.6b04096openalex-snapshotExploring the Colonic Metabolism of Grape and Strawberry Anthocyanins and Their in Vitro Apoptotic Effects in HT-29 Colon Cancer Cells
inferredcites →https://doi.org/10.1021/acs.jafc.8b02420openalex-snapshotDifferential Effects of Quercetin and Two of Its Derivatives, Isorhamnetin and Isorhamnetin-3-glucuronide, in Inhibiting the Proliferation of Human Breast-Cancer MCF-7 Cells
inferredcites →https://doi.org/10.1021/acs.jafc.8b02656openalex-snapshotReactive Oxygen Species and p53 Mediated Activation of p38 and Caspases is Critically Involved in Kaempferol Induced Apoptosis in Colorectal Cancer Cells
inferredcites →https://doi.org/10.1021/jf000025hopenalex-snapshotCatechin Contents of Foods Commonly Consumed in The Netherlands. 1. Fruits, Vegetables, Staple Foods, and Processed Foods
inferredcites →https://doi.org/10.1021/jf000026+openalex-snapshotCatechin Contents of Foods Commonly Consumed in The Netherlands. 2. Tea, Wine, Fruit Juices, and Chocolate Milk
inferredcites →https://doi.org/10.1021/jf0486850openalex-snapshotCharacterization of Anthocyanins and Proanthocyanidins in Some Cultivars ofRibes,Aronia, andSambucusand Their Antioxidant Capacity
inferredcites →https://doi.org/10.1021/jf049450ropenalex-snapshotIdentification and Quantification of Phenolic Compounds in Berries ofFragariaandRubusSpecies (Family Rosaceae)
inferredcites →https://doi.org/10.1021/jf062556xopenalex-snapshotMolecular Mechanisms of (−)-Epicatechin and Chlorogenic Acid on the Regulation of the Apoptotic and Survival/Proliferation Pathways in a Human Hepatoma Cell Line
inferredcites →https://doi.org/10.1021/jf070569kopenalex-snapshotOligomeric Procyanidins in Apple Polyphenol Are Main Active Components for Inhibition of Pancreatic Lipase and Triglyceride Absorption
inferredcites →https://doi.org/10.1021/pr500759eopenalex-snapshotHuman Milk Glycomics and Gut Microbial Genomics in Infant Feces Show a Correlation between Human Milk Oligosaccharides and Gut Microbiota: A Proof-of-Concept Study
inferredcites →https://doi.org/10.1038/srep31208openalex-snapshotNon-absorbable apple procyanidins prevent obesity associated with gut microbial and metabolomic changes
inferredcites →https://doi.org/10.1039/c5fo00890eopenalex-snapshotPurple carrot anthocyanins suppress lipopolysaccharide-induced inflammation in the co-culture of intestinal Caco-2 and macrophage RAW264.7 cells
inferredcites →https://doi.org/10.1039/c6fo01498dopenalex-snapshotCocoplum (Chrysobalanus icaco L.) anthocyanins exert anti-inflammatory activity in human colon cancer and non-malignant colon cells
inferredcites →https://doi.org/10.1039/c8fo00055gopenalex-snapshotBroad bean ( Vicia faba L.) pods: a rich source of bioactive ingredients with antimicrobial, antioxidant, enzyme inhibitory, anti-diabetic and health-promoting properties
inferredcites →https://doi.org/10.1055/s-0034-1368426openalex-snapshotThe Effect of Leonurus cardiaca Herb Extract and Some of its Flavonoids on Mitochondrial Oxidative Phosphorylation in the Heart
inferredcites →https://doi.org/10.1080/01480545.2019.1683187openalex-snapshotQuercetin and naringenin abate diethylnitrosamine/acetylaminofluorene-induced hepatocarcinogenesis in Wistar rats: the roles of oxidative stress, inflammation and cell apoptosis
inferredcites →https://doi.org/10.1080/01635581.2018.1460679openalex-snapshotSelective Cytotoxicity of Luteolin and Kaempferol on Cancerous Hepatocytes Obtained from Rat Model of Hepatocellular Carcinoma: Involvement of ROS-Mediated Mitochondrial Targeting
inferredcites →https://doi.org/10.1089/ars.2008.2279openalex-snapshotModulation of NF-κB–Dependent Gene Expression by H 2 O 2 : A Major Role for a Simple Chemical Process in a Complex Biological Response
inferredcites →https://doi.org/10.1089/jmf.2013.3077openalex-snapshotDelphinidin Suppresses PMA-Induced MMP-9 Expression by Blocking the NF-κB Activation Through MAPK Signaling Pathways in MCF-7 Human Breast Carcinoma Cells
inferredcites →https://doi.org/10.1093/abbs/gmq107openalex-snapshotQuercetin induces apoptosis by activating caspase-3 and regulating Bcl-2 and cyclooxygenase-2 pathways in human HL-60 cells
inferredcites →https://doi.org/10.1093/jn/136.11.2715openalex-snapshotQuercetin Induces Apoptosis via Caspase Activation, Regulation of Bcl-2, and Inhibition of PI-3-Kinase/Akt and ERK Pathways in a Human Hepatoma Cell Line (HepG2)
inferredcites →https://doi.org/10.1155/2017/1512745openalex-snapshotOxidative Stress Triggered by Apigenin Induces Apoptosis in a Comprehensive Panel of Human Cervical Cancer‐Derived Cell Lines
inferredcites →https://doi.org/10.1186/1749-8546-3-12openalex-snapshotGreen tea (Camellia sinensis) and cancer prevention: a systematic review of randomized trials and epidemiological studies
inferredcites →https://doi.org/10.1186/s12935-015-0186-0openalex-snapshotApigenin, a dietary flavonoid, inhibits proliferation of human bladder cancer T-24 cells via blocking cell cycle progression and inducing apoptosis
inferredcites →https://doi.org/10.1186/s13046-018-1010-1openalex-snapshotRETRACTED ARTICLE: Genistein inhibits stemness of SKOV3 cells induced by macrophages co-cultured with ovarian cancer stem-like cells through IL-8/STAT3 axis
inferredcites →https://doi.org/10.1186/s13046-021-01958-yopenalex-snapshotCorrection to: Genistein inhibits stemness of SKOV3 cells induced by macrophages co-cultured with ovarian cancer stem-like cells through IL-8/STAT3 axis
inferredcites →https://doi.org/10.1194/jlr.m800319-jlr200openalex-snapshotCardiolipin and electron transport chain abnormalities in mouse brain tumor mitochondria: lipidomic evidence supporting the Warburg theory of cancer
inferredcites →https://doi.org/10.1371/journal.pone.0110003openalex-snapshotInduction of Apoptosis and Antiproliferative Activity of Naringenin in Human Epidermoid Carcinoma Cell through ROS Generation and Cell Cycle Arrest
inferredcites →https://doi.org/10.1371/journal.pone.0149676openalex-snapshotThe Dietary Isoflavone Daidzein Reduces Expression of Pro-Inflammatory Genes through PPARα/γ and JNK Pathways in Adipocyte and Macrophage Co-Cultures
inferredcites →https://doi.org/10.3109/03602532.2014.1003649openalex-snapshotFlavonoid interactions during digestion, absorption, distribution and metabolism: a sequential structure–activity/property relationship-based approach in the study of bioavailability and bioactivity
inferredcites →https://doi.org/10.3389/fimmu.2019.00051openalex-snapshotImmunomodulatory Effects of Flavonoids: Possible Induction of T CD4+ Regulatory Cells Through Suppression of mTOR Pathway Signaling Activity
inferredcites →https://doi.org/10.3390/12071274openalex-snapshot(-)-Catechin in Cocoa and Chocolate: Occurence and Analysis of an Atypical Flavan-3-ol Enantiomer
inferredcites →https://doi.org/10.3390/antiox8020035openalex-snapshotPotential Role of Flavonoids in Treating Chronic Inflammatory Diseases with a Special Focus on the Anti-Inflammatory Activity of Apigenin
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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inferred← citeshttps://doi.org/10.1002/cbdv.71452openalex-snapshotComparative Evaluation of the Cytotoxic Effect of Dysphania ambrosioides Extracts Against Human Breast and Cervical Cancer Cells
inferred← citeshttps://doi.org/10.1002/cbdv.71728openalex-snapshotQuantitative Structure–Activity Relationship Approaches for Exploring the Anticancer Potential of Flavonoids
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inferred← citeshttps://doi.org/10.1002/jat.70401openalex-snapshotComparative Evaluation of Cytotoxic, Genotoxic, and Apoptotic Effects of Naringenin and Naringenin‐Oxime in Colorectal Cancer Cells
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inferred← citeshttps://doi.org/10.1007/s13596-024-00798-3openalex-snapshotAnnona muricata ethanolic extract protects BALB/c mice against colitis-associated colon cancer through modulation of cytokine levels and KRAS and APC expression
inferred← citeshttps://doi.org/10.1007/s13668-025-00713-5openalex-snapshotThe Role of Mediterranean Diet and Intermittent Fasting in Modulating Inflammation and Clinical Biochemistry Markers in Hereditary Cancer Syndromes: A Review
inferred← citeshttps://doi.org/10.1007/s40203-025-00379-5openalex-snapshotExploring the therapeutic potential of Premna barbata Wall. ex Schauer stem bark in colon cancer: apoptosis induction, cell cycle analysis, and in-silico insights
inferred← citeshttps://doi.org/10.1007/s44371-026-00643-3openalex-snapshotProcess optimization for the green synthesis of Tragopogon dubius extract silver nanoparticles and investigating its anticancer activity
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