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Hesperidin Improves Memory Function by Enhancing Neurogenesis in a Mouse Model of Alzheimer’s Disease
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1 of the 42 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-28): 10.1007/s11064-015-1525-1 (notice 2024-08-23).
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/j.bbi.2021.09.002openalex-snapshotTransplantation of gut microbiota derived from Alzheimer’s disease mouse model impairs memory function and neurogenesis in C57BL/6 mice
inferredcites →https://doi.org/10.1016/j.bcp.2011.11.009openalex-snapshotCyclic AMP response element-binding protein (CREB) phosphorylation: A mechanistic marker in the development of memory enhancing Alzheimer's disease therapeutics
inferredcites →https://doi.org/10.1016/j.jad.2019.09.013openalex-snapshotMetformin ameliorates stress-induced depression-like behaviors via enhancing the expression of BDNF by activating AMPK/CREB-mediated histone acetylation
inferredcites →https://doi.org/10.1038/mp.2009.67openalex-snapshotKnockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis
inferredcites →https://doi.org/10.1038/s41467-019-14026-zopenalex-snapshotIncreasing neurogenesis refines hippocampal activity rejuvenating navigational learning strategies and contextual memory throughout life
inferredcites →https://doi.org/10.1038/s41591-019-0375-9openalex-snapshotAdult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease
inferredcites →https://doi.org/10.1155/2013/102741openalex-snapshotNeuroprotective Effects of Hesperidin, a Plant Flavanone, on Rotenone-Induced Oxidative Stress and Apoptosis in a Cellular Model for Parkinson’s Disease
inferredcites →https://doi.org/10.1210/jc.2010-2879openalex-snapshotCitrus Polyphenol Hesperidin Stimulates Production of Nitric Oxide in Endothelial Cells while Improving Endothelial Function and Reducing Inflammatory Markers in Patients with Metabolic Syndrome
inferredcites →https://doi.org/10.1523/jneurosci.21-12-04125.2001openalex-snapshotBeta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease.
inferredcites →https://doi.org/10.3389/fnagi.2019.00062openalex-snapshotValproic Acid Stimulates Hippocampal Neurogenesis via Activating the Wnt/β-Catenin Signaling Pathway in the APP/PS1/Nestin-GFP Triple Transgenic Mouse Model of Alzheimer’s Disease
inferredcites →https://doi.org/10.3390/ijms18020268openalex-snapshotIntegral Characterization of Defective BDNF/TrkB Signalling in Neurological and Psychiatric Disorders Leads the Way to New Therapies
inferredcites →https://doi.org/10.3390/ijms21124492openalex-snapshotTrans-Cinnamaldehyde Alleviates Amyloid-Beta Pathogenesis via the SIRT1-PGC1α-PPARγ Pathway in 5XFAD Transgenic Mice
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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inferred← citeshttps://doi.org/10.1002/ame2.70244openalex-snapshotMultipathway modulation of neuroinflammation and oxidative stress by hesperidin in a rat single prolonged stress model of post‐traumatic stress disorder
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inferred← citeshttps://doi.org/10.1007/s11064-026-04833-4openalex-snapshotA Combination of Artemisinin, N-acetylcysteine, Resveratrol, and Hesperidin Ameliorates Hippocampal Damage and Pathological Features in an Experimental Model of Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1007/s40473-024-00284-9openalex-snapshotThe Impact of Hesperidin on Cognitive Deficit and Neurobehavioural Disorders: A Systematic Review and Meta-Analysis of Preclinical Individual Studies
inferred← citeshttps://doi.org/10.1016/j.fitote.2023.105792openalex-snapshotMetabolite profiling, enzyme inhibitory activity and antioxidant potential of different extracts from Glycyrrhiza foetida Desf. (Fabaceae, Galegeae, Glycyrrhizinae)
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inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2023.10.408openalex-snapshotHesperidin ameliorates Amyloid-β toxicity and enhances oxidative stress resistance and lifespan of Caenorhabditis elegans through acr-16 mediated activation of the autophagy pathway
inferred← citeshttps://doi.org/10.1016/j.jep.2026.122084openalex-snapshotDitan Decoction alleviates glutamate excitotoxicity in an Aβ-induced Alzheimer's disease-like model through the regulation of ERBB2/PI3K/AKT signaling pathway
inferred← citeshttps://doi.org/10.1016/j.jfca.2025.107553openalex-snapshotComparison of ultrasound-assisted extraction and modified QuEChERS technique for extraction of hesperidin from lemon peel (Citrus limon L.) as determined by HPLC
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inferred← citeshttps://doi.org/10.1016/j.prmcm.2025.100718openalex-snapshotTraditional wisdom to modern science: Hesperetin and naringenin as emerging traditional Chinese medicine-based treatments for Alzheimer’s disease
inferred← citeshttps://doi.org/10.1017/s0007114523002301openalex-snapshotTomato and lemon extracts synergistically improve cognitive function by increasing brain-derived neurotrophic factor levels in aged mice
inferred← citeshttps://doi.org/10.1021/acs.biomac.3c01452openalex-snapshotMultifunctional Nanoprobe Au@Gd-SiO2-HA-Lyp-1/DOX with Dual-Targeting Functions Derived from HA and LyP-1: Diagnostic and Therapeutic Potential for Tumor Lymphatic Metastasis
inferred← citeshttps://doi.org/10.1080/1028415x.2023.2296165openalex-snapshotThe impact of flavonoids and BDNF on neurogenic process in various physiological/pathological conditions including ischemic insults: a narrative review
inferred← citeshttps://doi.org/10.1111/cns.14509openalex-snapshotSurvivin enhances hippocampal neurogenesis and cognitive function in Alzheimer's disease mouse model
inferred← citeshttps://doi.org/10.1111/cns.14661openalex-snapshotOligodendrocyte‐derived exosomes‐containing SIRT2 ameliorates depressive‐like behaviors and restores hippocampal neurogenesis and synaptic plasticity via the AKT / GSK ‐3β pathway in depressed mice
inferred← citeshttps://doi.org/10.1186/s12951-025-03552-2openalex-snapshotUnveiling new therapeutic targets for esophageal cancer treatment through single-cell transcriptomics: pH-responsive nanobubbles enhance the efficacy of 125I radiotherapy
inferred← citeshttps://doi.org/10.1208/s12249-025-03297-zopenalex-snapshotImproved Oral Bioavailability and Brain Distribution of Hesperidin via Cochleate Formulation: Statistical Optimization and Pharmacokinetic Study
inferred← citeshttps://doi.org/10.3389/fnut.2025.1706146openalex-snapshotHarnessing hesperidin for brain metabolism: epigenetic signatures, cellular homeostasis, synaptic function, and neuroprotection in age-related diseases and neurodegenerative diseases
inferred← citeshttps://doi.org/10.3389/fphar.2023.1213252openalex-snapshotGlucosyl hesperidin exhibits more potent anxiolytic activity than hesperidin accompanied by the attenuation of noradrenaline induction in a zebrafish model
inferred← citeshttps://doi.org/10.3390/ijms26094352openalex-snapshotN-Acetylcysteine Attenuates Aβ-Mediated Oxidative Stress, Blood–Brain Barrier Leakage, and Renal Dysfunction in 5xFAD Mice
inferred← citeshttps://doi.org/10.3390/ijms26188907openalex-snapshotNeuroactive Phytochemicals as Multi-Target Modulators of Mental Health and Cognitive Function: An Integrative Review
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