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New Insights into the Pros and Cons of the Clinical Use of Vitamin K Antagonists (VKAs) Versus Direct Oral Anticoagulants (DOACs)

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Outgoing claims: the papers this work cites, builds on, or argues with.

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INTRAMUSCULAR ADMINISTRATION OF THE ANTICOAGULANT WARFARIN (COUMADIN) SODIUM

inferredcites →https://doi.org/10.1002/1097-4636(20010315)54:4<547::aid-jbm110>3.0.co;2-2openalex-snapshot

Correlations between osteocalcin content, degree of mineralization, and mechanical properties ofC. Carpio rib bone

inferredcites →https://doi.org/10.1002/jbmr.2039openalex-snapshot

Elastin Haploinsufficiency Impedes the Progression of Arterial Calcification in MGP-Deficient Mice

inferredcites →https://doi.org/10.1002/jbmr.539openalex-snapshot

The antioxidant tempol ameliorates arterial medial calcification in uremic rats: Important role of oxidative stress in the pathogenesis of vascular calcification in chronic kidney disease

inferredcites →https://doi.org/10.1002/mnfr.201300743openalex-snapshot

The realm of vitamin K dependent proteins: Shifting from coagulation toward calcification

inferredcites →https://doi.org/10.1007/s00125-014-3348-zopenalex-snapshot

RANKL–OPG and RAGE modulation in vascular calcification and diabetes: novel targets for therapy

inferredcites →https://doi.org/10.1007/s00228-005-0043-5openalex-snapshot

Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939—an oral, direct Factor Xa inhibitor—after multiple dosing in healthy male subjects

inferredcites →https://doi.org/10.1007/s00281-011-0281-9openalex-snapshot

The roles of thrombin and protease-activated receptors in inflammation

inferredcites →https://doi.org/10.1007/s10557-012-6411-3openalex-snapshot

The Beneficial Effects of a Direct Thrombin Inhibitor, Dabigatran Etexilate, on the Development and Stability of Atherosclerotic Lesions in Apolipoprotein E-deficient Mice

inferredcites →https://doi.org/10.1007/s11239-013-1026-5openalex-snapshot

Thrombin generation and atherosclerosis

inferredcites →https://doi.org/10.1007/s11239-013-1029-2openalex-snapshot

A clinical and pharmacologic assessment of once-daily versus twice-daily dosing for rivaroxaban

inferredcites →https://doi.org/10.1007/s12020-014-0401-0openalex-snapshot

A four-season molecule: osteocalcin. Updates in its physiological roles

inferredcites →https://doi.org/10.1016/0003-9861(91)90325-dopenalex-snapshot

Purification and characterization of recombinant antistasin: A leech-derived inhibitor of coagulation factor Xa

inferredcites →https://doi.org/10.1016/0006-291x(87)90458-xopenalex-snapshot

The effect of Gla-containing proteins on the precipitation of insoluble salts

inferredcites →https://doi.org/10.1016/0304-4165(90)90072-5openalex-snapshot

Comparison of the vitamins K1, K2 and K3 as cofactors for the hepatic vitamin K-dependent carboxylase

inferredcites →https://doi.org/10.1016/j.ajpath.2011.02.004openalex-snapshot

Microcalcifications in Early Intimal Lesions of Atherosclerotic Human Coronary Arteries

inferredcites →https://doi.org/10.1016/j.atherosclerosis.2008.07.010openalex-snapshot

High dietary menaquinone intake is associated with reduced coronary calcification

inferredcites →https://doi.org/10.1016/j.atherosclerosis.2015.02.040openalex-snapshot

Prevention of vasculopathy by vitamin K supplementation: Can we turn fiction into fact?

inferredcites →https://doi.org/10.1016/j.blre.2012.03.002openalex-snapshot

Vascular calcification: The price to pay for anticoagulation therapy with vitamin K-antagonists

inferredcites →https://doi.org/10.1016/j.bone.2011.11.017openalex-snapshot

Ucma is not necessary for normal development of the mouse skeleton

inferredcites →https://doi.org/10.1016/j.cca.2014.08.034openalex-snapshot

Vascular calcification: from pathophysiology to biomarkers

inferredcites →https://doi.org/10.1016/j.jbiomech.2007.11.029openalex-snapshot

Influence of microcalcifications on vulnerable plaque mechanics using FSI modeling

inferredcites →https://doi.org/10.1016/j.jcmg.2012.01.023openalex-snapshot

Accelerated In Vivo Thrombin Formation Independently Predicts the Presence and Severity of CT Angiographic Coronary Atherosclerosis

inferredcites →https://doi.org/10.1016/j.jmbbm.2008.10.010openalex-snapshot

Effect of osteocalcin deficiency on the nanomechanics and chemistry of mouse bones

inferredcites →https://doi.org/10.1016/j.molmed.2008.08.001openalex-snapshot

Factor Xa: at the crossroads between coagulation and signaling in physiology and disease

inferredcites →https://doi.org/10.1016/j.molmed.2012.12.008openalex-snapshot

Vitamin K-dependent carboxylation of matrix Gla-protein: a crucial switch to control ectopic mineralization

inferredcites →https://doi.org/10.1016/j.pharmthera.2012.01.007openalex-snapshot

Physiology, pharmacology, and therapeutic potential of protease-activated receptors in vascular disease

inferredcites →https://doi.org/10.1016/j.thromres.2012.08.304openalex-snapshot

The effects of warfarin and edoxaban, an oral direct factor Xa inhibitor, on gammacarboxylated (Gla-osteocalcin) and undercarboxylated osteocalcin (uc-osteocalcin) in rats

inferredcites →https://doi.org/10.1016/j.vph.2014.06.001openalex-snapshot

Functional role of protease activated receptors in vascular biology

inferredcites →https://doi.org/10.1016/j.yexcr.2014.01.011openalex-snapshot

Hydroxyapatite and calcified elastin induce osteoblast-like differentiation in rat aortic smooth muscle cells

inferredcites →https://doi.org/10.1016/s0021-9258(19)41365-3openalex-snapshot

A new carboxylation reaction. The vitamin K-dependent incorporation of H-14-CO3- into prothrombin.

inferredcites →https://doi.org/10.1016/s0049-3848(03)00252-4openalex-snapshot

Medical indications and considerations for future clinical decision making

inferredcites →https://doi.org/10.1016/s0140-6736(13)61754-7openalex-snapshot

18F-fluoride positron emission tomography for identification of ruptured and high-risk coronary atherosclerotic plaques: a prospective clinical trial

inferredcites →https://doi.org/10.1016/s0140-6736(60)92299-6openalex-snapshot

ANTICOAGULANT DRUGS IN THE TREATMENT OF PULMONARY EMBOLISM

inferredcites →https://doi.org/10.1016/s0140-6736(98)10266-0openalex-snapshot

Venous thrombosis: a multicausal disease

inferredcites →https://doi.org/10.1016/s0304-4165(02)00147-2openalex-snapshot

Differential lipoprotein transport pathways of K-vitamins in healthy subjects

inferredcites →https://doi.org/10.1017/s0007114513001013openalex-snapshot

The role of menaquinones (vitamin K 2 ) in human health

inferredcites →https://doi.org/10.1021/ja207628kopenalex-snapshot

Matrix Gla Protein Inhibits Ectopic Calcification by a Direct Interaction with Hydroxyapatite Crystals

inferredcites →https://doi.org/10.1038/202498a0openalex-snapshot

An Enzyme Cascade in the Blood Clotting Mechanism, and its Function as a Biochemical Amplifier

inferredcites →https://doi.org/10.1038/382448a0openalex-snapshot

Increased bone formation in osteocalcin-deficient mice

inferredcites →https://doi.org/10.1038/386078a0openalex-snapshot

Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein

inferredcites →https://doi.org/10.1038/ki.2012.477openalex-snapshot

Dietary vitamin K and therapeutic warfarin alter the susceptibility to vascular calcification in experimental chronic kidney disease

inferredcites →https://doi.org/10.1042/bj3170059openalex-snapshot

Nucleation and inhibition of hydroxyapatite formation by mineralized tissue proteins

inferredcites →https://doi.org/10.1042/cs20100589openalex-snapshot

Circulating levels of non-phosphorylated undercarboxylated matrix Gla protein are associated with disease severity in patients with chronic heart failure

inferredcites →https://doi.org/10.1053/j.ajkd.2011.10.041openalex-snapshot

Effect of Vitamin K2 Supplementation on Functional Vitamin K Deficiency in Hemodialysis Patients: A Randomized Trial

inferredcites →https://doi.org/10.1055/s-0034-1381233openalex-snapshot

Combined Administration of Antibiotics and Direct Oral Anticoagulants: A Renewed Indication for Laboratory Monitoring?

inferredcites →https://doi.org/10.1055/s-0035-1546827openalex-snapshot

Laboratory Testing in the Era of Direct or Non–Vitamin K Antagonist Oral Anticoagulants: A Practical Guide to Measuring Their Activity and Avoiding Diagnostic Errors

inferredcites →https://doi.org/10.1055/s-0037-1615000openalex-snapshot

Thrombin Stimulates Smooth Muscle Cell Procollagen Synthesis and mRNA Levels via a PAR-1 Mediated Mechanism

inferredcites →https://doi.org/10.1055/s-0037-1615780openalex-snapshot

Biochemistry and Physiology of Blood Coagulation

inferredcites →https://doi.org/10.1055/s-0037-1616233openalex-snapshot

Atherosclerosis and Thrombosis: Lessons from Animal Models

inferredcites →https://doi.org/10.1056/nejm198212303072704openalex-snapshot

Different Intensities of Oral Anticoagulant Therapy in the Treatment of Proximal-Vein Thrombosis

inferredcites →https://doi.org/10.1056/nejm199711063371901openalex-snapshot

A Comparison of Recombinant Hirudin with a Low-Molecular-Weight Heparin to Prevent Thromboembolic Complications after Total Hip Replacement

inferredcites →https://doi.org/10.1056/nejm200008313430903openalex-snapshot

Predictors of Outcome in Severe, Asymptomatic Aortic Stenosis

inferredcites →https://doi.org/10.1056/nejme1506600openalex-snapshot

Targeted Anti-Anticoagulants

inferredcites →https://doi.org/10.1056/nejmoa030104openalex-snapshot

Secondary Prevention of Venous Thromboembolism with the Oral Direct Thrombin Inhibitor Ximelagatran

inferredcites →https://doi.org/10.1056/nejmoa0800374openalex-snapshot

Rivaroxaban versus Enoxaparin for Thromboprophylaxis after Hip Arthroplasty

inferredcites →https://doi.org/10.1056/nejmoa0901301openalex-snapshot

Effect of Clopidogrel Added to Aspirin in Patients with Atrial Fibrillation

inferredcites →https://doi.org/10.1056/nejmoa0905561openalex-snapshot

Dabigatran versus Warfarin in Patients with Atrial Fibrillation

inferredcites →https://doi.org/10.1056/nejmoa0906598openalex-snapshot

Dabigatran versus Warfarin in the Treatment of Acute Venous Thromboembolism

inferredcites →https://doi.org/10.1056/nejmoa1006885openalex-snapshot

Apixaban versus Enoxaparin for Thromboprophylaxis after Hip Replacement

inferredcites →https://doi.org/10.1056/nejmoa1007903openalex-snapshot

Oral Rivaroxaban for Symptomatic Venous Thromboembolism

inferredcites →https://doi.org/10.1056/nejmoa1009638openalex-snapshot

Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation

inferredcites →https://doi.org/10.1056/nejmoa1107039openalex-snapshot

Apixaban versus Warfarin in Patients with Atrial Fibrillation

inferredcites →https://doi.org/10.1056/nejmoa1502000openalex-snapshot

Idarucizumab for Dabigatran Reversal

inferredcites →https://doi.org/10.1056/nejmra1011670openalex-snapshot

The Hemostatic System as a Modulator of Atherosclerosis

inferredcites →https://doi.org/10.1073/pnas.0606310103openalex-snapshot

A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps

inferredcites →https://doi.org/10.1073/pnas.73.5.1447openalex-snapshot

Characterization of a gamma-carboxyglutamic acid-containing protein from bone.

inferredcites →https://doi.org/10.1074/jbc.m109.007013openalex-snapshot

Mineralization by Inhibitor Exclusion

inferredcites →https://doi.org/10.1074/jbc.m407180200openalex-snapshot

Processing and Transport of Matrix γ-Carboxyglutamic Acid Protein and Bone Morphogenetic Protein-2 in Cultured Human Vascular Smooth Muscle Cells

inferredcites →https://doi.org/10.1079/bjn20051630openalex-snapshot

Menadione is a metabolite of oral vitamin K

inferredcites →https://doi.org/10.1083/jcb.200402046openalex-snapshot

Extracellular matrix mineralization is regulated locally; different roles of two gla-containing proteins

inferredcites →https://doi.org/10.1084/jem.20060217openalex-snapshot

Are hemostasis and thrombosis two sides of the same coin?

inferredcites →https://doi.org/10.1093/cvr/cvt112openalex-snapshot

Factor-Xa-induced mitogenesis and migration require sphingosine kinase activity and S1P formation in human vascular smooth muscle cells

inferredcites →https://doi.org/10.1093/jn/134.11.3100openalex-snapshot

Dietary Intake of Menaquinone Is Associated with a Reduced Risk of Coronary Heart Disease: The Rotterdam Study

inferredcites →https://doi.org/10.1093/ndt/gfu224openalex-snapshot

The impact of warfarin on the rate of progression of aortic stiffness in hemodialysis patients: a longitudinal study

inferredcites →https://doi.org/10.1093/ndt/gfv111openalex-snapshot

Vascular calcification in chronic kidney disease: an update

inferredcites →https://doi.org/10.1097/01.asn.0000141960.01035.28openalex-snapshot

Human Vascular Smooth Muscle Cells Undergo Vesicle-Mediated Calcification in Response to Changes in Extracellular Calcium and Phosphate Concentrations

inferredcites →https://doi.org/10.1111/j.1538-7836.2005.01166.xopenalex-snapshot

In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939—an oral, direct Factor Xa inhibitor

inferredcites →https://doi.org/10.1111/j.1538-7836.2005.01419.xopenalex-snapshot

The vitamin K cycle

inferredcites →https://doi.org/10.1111/j.1538-7836.2007.02748.xopenalex-snapshot

Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: the RE‐MODEL randomized trial

inferredcites →https://doi.org/10.1111/j.1538-7836.2007.02758.xopenalex-snapshot

Post‐translational modifications regulate matrix Gla protein function: importance for inhibition of vascular smooth muscle cell calcification

inferredcites →https://doi.org/10.1111/j.1538-7836.2011.04263.xopenalex-snapshot

Circulating matrix γ‐carboxyglutamate protein (MGP) species are refractory to vitamin K treatment in a new case of Keutel syndrome

inferredcites →https://doi.org/10.1111/jth.12203openalex-snapshot

Effect of low-dose supplements of menaquinone-7 (vitamin K2) on the stability of oral anticoagulant treatment: dose–response relationship in healthy volunteers

inferredcites →https://doi.org/10.1124/dmd.113.054353openalex-snapshot

Identification of Carboxylesterase-Dependent Dabigatran Etexilate Hydrolysis

inferredcites →https://doi.org/10.1124/mol.114.096446openalex-snapshot

Characterization of Thrombin-Bound Dabigatran Effects on Protease-Activated Receptor-1 Expression and Signaling In Vitro

inferredcites →https://doi.org/10.1136/bmj.g4517openalex-snapshot

Dabigatran, bleeding, and the regulators

inferredcites →https://doi.org/10.1136/bmj.g4670openalex-snapshot

Dabigatran: how the drug company withheld important analyses

inferredcites →https://doi.org/10.1155/2011/432080openalex-snapshot

Evaluation of Plaque Stability of Advanced Atherosclerotic Lesions in Apo E-Deficient Mice after Treatment with the Oral Factor Xa Inhibitor Rivaroxaban

inferredcites →https://doi.org/10.1159/000054147openalex-snapshot

Determination of phylloquinone and menaquinones in food. Effect of food matrix on circulating vitamin K concentrations.

inferredcites →https://doi.org/10.1159/000124863openalex-snapshot

The Circulating Inactive Form of Matrix Gla Protein (ucMGP) as a Biomarker for Cardiovascular Calcification

inferredcites →https://doi.org/10.1159/000289575openalex-snapshot

Undercarboxylated Osteocalcin Is a Biomarker of Carotid Calcification in Patients with Essential Hypertension

inferredcites →https://doi.org/10.1159/000313877openalex-snapshot

Upregulation of Proteinase-Activated Receptor-2 and Increased Response to Trypsin in Endothelial Cells after Exposure to Oxidative Stress in Rat Aortas

inferredcites →https://doi.org/10.1159/000350089openalex-snapshot

Sox9 Modulates Proliferation and Expression of Osteogenic Markers of Adipose-Derived Stem Cells (ASC)

inferredcites →https://doi.org/10.1160/th06-05-0234openalex-snapshot

Emerging anticoagulants for the treatment of venous thromboembolism

inferredcites →https://doi.org/10.1160/th07-08-0481openalex-snapshot

Thrombin and protease-activated receptors (PARs) in atherothrombosis

inferredcites →https://doi.org/10.1160/th07-11-0693openalex-snapshot

The direct thrombin inhibitor hirudin

inferredcites →https://doi.org/10.1160/th08-03-0147openalex-snapshot

Metabolism and cell biology of vitamin K

inferredcites →https://doi.org/10.1160/th08-04-0116openalex-snapshot

Pharmacogenetic differences between warfarin, acenocoumarol and phenprocoumon

inferredcites →https://doi.org/10.1160/th13-09-0730openalex-snapshot

Targeting factor Xa and thrombin: impact on coagulation and beyond

inferredcites →https://doi.org/10.1160/th14-03-0268openalex-snapshot

Differential cellular effects of old and new oral anticoagulants: consequences to the genesis and progression of atherosclerosis

inferredcites →https://doi.org/10.1161/01.atv.0000173313.46222.43openalex-snapshot

Novel Conformation-Specific Antibodies Against Matrix γ-Carboxyglutamic Acid (Gla) Protein

inferredcites →https://doi.org/10.1161/01.atv.18.9.1400openalex-snapshot

Warfarin Causes Rapid Calcification of the Elastic Lamellae in Rat Arteries and Heart Valves

inferredcites →https://doi.org/10.1161/01.atv.19.12.3014openalex-snapshot

Altered Vascular Injury Responses in Mice Deficient in Protease-Activated Receptor-1

inferredcites →https://doi.org/10.1161/01.cir.0000148131.41425.e9openalex-snapshot

Spotty Calcification Typifies the Culprit Plaque in Patients With Acute Myocardial Infarction

inferredcites →https://doi.org/10.1161/01.cir.19.1.97openalex-snapshot

The Discovery of Dicumarol and Its Sequels

inferredcites →https://doi.org/10.1161/01.cir.90.4.1631openalex-snapshot

Randomized trial of intravenous heparin versus recombinant hirudin for acute coronary syndromes. The Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIa Investigators.

inferredcites →https://doi.org/10.1161/01.cir.99.19.2590openalex-snapshot

Protease-Activated Receptor-2 Involvement in Hypotension in Normal and Endotoxemic Rats In Vivo

inferredcites →https://doi.org/10.1161/atvbaha.111.233601openalex-snapshot

Osteocalcin

inferredcites →https://doi.org/10.1161/atvbaha.113.302244openalex-snapshot

Warfarin Induces Cardiovascular Damage in Mice

inferredcites →https://doi.org/10.1161/atvbaha.114.303402openalex-snapshot

Antidotes for Novel Oral Anticoagulants

inferredcites →https://doi.org/10.1161/atvbaha.114.304823openalex-snapshot

Gla-Rich Protein Acts as a Calcification Inhibitor in the Human Cardiovascular System

inferredcites →https://doi.org/10.1161/atvbaha.115.303397openalex-snapshot

Overview of the New Oral Anticoagulants

inferredcites →https://doi.org/10.1161/circresaha.110.219071openalex-snapshot

Inhibition of Bone Morphogenetic Proteins Protects Against Atherosclerosis and Vascular Calcification

inferredcites →https://doi.org/10.1161/circresaha.110.234278openalex-snapshot

The Regulation of Valvular and Vascular Sclerosis by Osteogenic Morphogens

inferredcites →https://doi.org/10.1161/circresaha.112.276741openalex-snapshot

Oral Direct Factor Xa Inhibitors

inferredcites →https://doi.org/10.1161/circulationaha.106.654913openalex-snapshot

Multimodality Molecular Imaging Identifies Proteolytic and Osteogenic Activities in Early Aortic Valve Disease

inferredcites →https://doi.org/10.1161/hh1001.091447openalex-snapshot

New Tricks for Old Dogs

inferredcites →https://doi.org/10.1161/hh2401.101070openalex-snapshot

Smooth Muscle Cell Phenotypic Transition Associated With Calcification

inferredcites →https://doi.org/10.1172/jci16913openalex-snapshot

Essential role for proteinase-activated receptor-2 in arthritis

inferredcites →https://doi.org/10.1177/107602960100700303openalex-snapshot

State-of-the-Art Review: Anticoagulation: The Present and Future

inferredcites →https://doi.org/10.1177/107602960100700403openalex-snapshot

State-of-the-Art Review: The Oral Anticoagulant Saga: Past, Present, and Future

inferredcites →https://doi.org/10.1182/blood-2006-07-035345openalex-snapshot

Regression of warfarin-induced medial elastocalcinosis by high intake of vitamin K in rats

inferredcites →https://doi.org/10.1182/blood-2006-08-040709openalex-snapshot

Vitamin K–containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7

inferredcites →https://doi.org/10.1182/blood-2014-04-571232openalex-snapshot

Direct oral anticoagulants compared with vitamin K antagonists for acute venous thromboembolism: evidence from phase 3 trials

inferredcites →https://doi.org/10.1182/blood.v89.12.4378openalex-snapshot

Thrombin Generation by Apoptotic Vascular Smooth Muscle Cells

inferredcites →https://doi.org/10.1185/03007995.2014.951425openalex-snapshot

The potential of target-specific oral anticoagulants for the acute and long-term treatment of venous thromboembolism

inferredcites →https://doi.org/10.1302/0301-620x.91b5.21691openalex-snapshot

Oral rivaroxaban for the prevention of symptomatic venous thromboembolism after elective hip and knee replacement

inferredcites →https://doi.org/10.1378/chest.114.5_supplement.715sopenalex-snapshot

New Antithrombotic Agents

inferredcites →https://doi.org/10.1378/chest.1412s3openalex-snapshot

Executive Summary

inferredcites →https://doi.org/10.1517/13543784.15.8.843openalex-snapshot

Novel factor Xa inhibitors for prevention and treatment of thromboembolic diseases

inferredcites →https://doi.org/10.1517/14728222.2011.553608openalex-snapshot

Blood coagulation factor Xa as an emerging drug target

inferredcites →https://doi.org/10.1681/asn.2010040339openalex-snapshot

Circulating Nonphosphorylated Carboxylated Matrix Gla Protein Predicts Survival in ESRD

inferredcites →https://doi.org/10.2147/vhrm.s4822openalex-snapshot

Vascular calcifications as a marker of increased cardiovascular risk: A meta-analysis

inferredcites →https://doi.org/10.2353/ajpath.2009.090474openalex-snapshot

Gla-Rich Protein Is a Novel Vitamin K-Dependent Protein Present in Serum That Accumulates at Sites of Pathological Calcifications

inferredcites →https://doi.org/10.3109/10409238.2013.791659openalex-snapshot

Structural and functional insights into human vitamin K epoxide reductase and vitamin K epoxide reductase-like1

inferredcites →https://doi.org/10.3945/an.111.001685openalex-snapshot

Gla-Rich Protein, a New Player in Tissue Calcification?

inferredcites →https://doi.org/10.3945/jn.113.187740openalex-snapshot

Dietary Intake of Vitamin K Is Inversely Associated with Mortality Risk

inferredcites →https://doi.org/10.5114/aoms.2014.40742openalex-snapshot

Experimental research Thrombin inhibition by dabigatran attenuates atherosclerosis in ApoE deficient mice

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Transcatheter aortic valve implantation in patients with uninterrupted vitamin K antagonists

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Effect of Genotype on the Pharmacokinetics and Bleeding Events of Direct Oral Anticoagulants: A Systematic Review and Meta‐analysis

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Antikoagulation und Thrombozytenaggregationshemmung bei chronischer Nierenkrankheit

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Orale Antikoagulation mit Vitamin K-Antagonisten – ein Update

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Arrhythmia Recurrence After Atrial Fibrillation Ablation: Impact of Warfarin vs. Non-Vitamin K Antagonist Oral Anticoagulants

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Efficacy and safety of more potent antiplatelet therapy with vorapaxar in patients with impaired renal function

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The Effects of Osteoporotic and Non-osteoporotic Medications on Fracture Risk and Bone Mineral Density

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Recurrent Thrombosis With Direct Oral Anticoagulants in Antiphospholipid Syndrome: A Systematic Literature Review and Meta-analysis

inferred← citeshttps://doi.org/10.1016/j.ejmech.2019.111722openalex-snapshot

Discovery of novel, potent, isosteviol-based antithrombotic agents

inferred← citeshttps://doi.org/10.1016/j.ijcard.2022.01.063openalex-snapshot

Renal decline in patients with non-valvular atrial fibrillation treated with rivaroxaban or warfarin: A population-based study from the United Kingdom

inferred← citeshttps://doi.org/10.1016/j.ijcard.2024.131894openalex-snapshot

Comparative effectiveness of factor Xa non-vitamin K antagonist oral anticoagulants versus phenprocoumon in patients with non-valvular atrial fibrillation

inferred← citeshttps://doi.org/10.1016/j.jchromb.2021.122822openalex-snapshot

Affinity ultrafiltration and UPLC-HR-Orbitrap-MS based screening of thrombin-targeted small molecules with anticoagulation activity from Poecilobdella manillensis

inferred← citeshttps://doi.org/10.1016/j.jcms.2019.01.049openalex-snapshot

Bleeding assessment in oral surgery: A cohort study comparing individuals on anticoagulant therapy and a non-anticoagulated group

inferred← citeshttps://doi.org/10.1016/j.kint.2016.11.028openalex-snapshot

Anticoagulation, atrial fibrillation, and chronic kidney disease—whose side are you on?

inferred← citeshttps://doi.org/10.1016/j.kint.2021.06.037openalex-snapshot

Vitamin K and cardiovascular complications in chronic kidney disease patients

inferred← citeshttps://doi.org/10.1016/j.mtbio.2025.102378openalex-snapshot

Selective targeting of coagulation factor X Gla domain by negatively charged gold nanoparticles: a novel method for controlled antithrombotic therapy

inferred← citeshttps://doi.org/10.1016/j.rpth.2025.102713openalex-snapshot

Exploration of the plasma proteomic profile of patients at risk of thromboembolic events

inferred← citeshttps://doi.org/10.1016/j.semerg.2018.10.008openalex-snapshot

Anticoagulantes orales directos en la fibrilación auricular no valvular: cómo mejorar su uso en España

inferred← citeshttps://doi.org/10.1016/j.transproceed.2020.02.171openalex-snapshot

Incidence of Direct Oral Anticoagulant Prescriptions in Kidney Transplant Recipients in Ontario, Canada

inferred← citeshttps://doi.org/10.1055/a-1200-7895openalex-snapshot

Wie antikoaguliert man ältere und fragile Patienten?

inferred← citeshttps://doi.org/10.1055/a-1547-4726openalex-snapshot

Wie antikoaguliert man ältere und fragile Patienten?

inferred← citeshttps://doi.org/10.1055/a-1792-7094openalex-snapshot

Sicherheit und Effektivität der oralen Antikoagulation bei Vorhofflimmern und Niereninsuffizienz im Praxisalltag

inferred← citeshttps://doi.org/10.1055/a-1814-6149openalex-snapshot

Wie antikoaguliert man ältere und fragile Patienten?

inferred← citeshttps://doi.org/10.1055/a-1949-8104openalex-snapshot

Gerinnungsmanagement in der schweren, fortgeschrittenen Niereninsuffizienz

inferred← citeshttps://doi.org/10.1055/s-0038-1675578openalex-snapshot

Vitamin K Antagonists, Non–Vitamin K Antagonist Oral Anticoagulants, and Vascular Calcification in Patients with Atrial Fibrillation

inferred← citeshttps://doi.org/10.1055/s-0040-1721665openalex-snapshot

Use of Non-vitamin K Antagonist Oral Anticoagulants for Stroke Prevention across the Stroke Spectrum: Progress and Prospects

inferred← citeshttps://doi.org/10.1080/03007995.2021.1947217openalex-snapshot

Kidney, limb and ophthalmic complications, and death in patients with nonvalvular atrial fibrillation and type 2 diabetes prescribed rivaroxaban or warfarin: an electronic health record analysis

inferred← citeshttps://doi.org/10.1080/03007995.2022.2061705openalex-snapshot

Worsening of kidney function in patients with atrial fibrillation and chronic kidney disease: evidence from the real-world CALLIPER study

inferred← citeshttps://doi.org/10.1080/03007995.2026.2627734openalex-snapshot

Contemporary approaches to perioperative anticoagulant management in surgical patients: a literature review

inferred← citeshttps://doi.org/10.1080/08998280.2023.2247958openalex-snapshot

The efficacy and safety of direct factor Xa inhibitors versus vitamin K antagonists for atrial fibrillation in patients on hemodialysis: a meta-analysis of randomized controlled trials

inferred← citeshttps://doi.org/10.1093/ehjqcco/qcz047openalex-snapshot

Rivaroxaban vs. warfarin and renal outcomes in non-valvular atrial fibrillation patients with diabetes

inferred← citeshttps://doi.org/10.1093/eurheartj/suaa182openalex-snapshot

Concomitant diabetes with atrial fibrillation and anticoagulation management considerations

inferred← citeshttps://doi.org/10.1093/europace/euab184openalex-snapshot

Medical therapies for prevention of cardiovascular and renal events in patients with atrial fibrillation and diabetes mellitus

inferred← citeshttps://doi.org/10.1097/md.0000000000017628openalex-snapshot

Effect of anticoagulation therapy in older patients with chronic kidney disease and atrial fibrillation

inferred← citeshttps://doi.org/10.1111/jth.15289openalex-snapshot

Off‐target effects of oral anticoagulants – vascular effects of vitamin K antagonist and non‐vitamin K antagonist oral anticoagulant dabigatran etexilate

inferred← citeshttps://doi.org/10.1139/bcb-2021-0441openalex-snapshot

Overexpression of protein disulfide isomerase enhances vitamin K epoxide reductase activity

inferred← citeshttps://doi.org/10.1159/000491400openalex-snapshot

NOACs in Anesthesiology

inferred← citeshttps://doi.org/10.11606/d.5.2019.tde-10072019-144852openalex-snapshot

Avaliação do impacto da inclusão de polimorfismos nos genes ABCB1 e CYP4F2 em algoritmo farmacogenético para dosagem personalizada do anticoagulante varfarina

inferred← citeshttps://doi.org/10.1161/atvbaha.119.312787openalex-snapshot

Role of Vascular Smooth Muscle Cell Phenotypic Switching and Calcification in Aortic Aneurysm Formation

inferred← citeshttps://doi.org/10.1161/atvbaha.120.315506openalex-snapshot

Endoplasmic Reticulum Stress Mediates Vascular Smooth Muscle Cell Calcification via Increased Release of Grp78 (Glucose-Regulated Protein, 78 kDa)-Loaded Extracellular Vesicles

inferred← citeshttps://doi.org/10.1177/10742484231202655openalex-snapshot

Evidence-based Management of Major Bleeding in Patients Receiving Direct Oral Anticoagulants: An Updated Narrative Review on the Role of Specific Reversal Agents

inferred← citeshttps://doi.org/10.1177/1076029619868535openalex-snapshot

Rivaroxaban’s Impact on Renal Decline in Patients With Nonvalvular Atrial Fibrillation: A US MarketScan Claims Database Analysis

inferred← citeshttps://doi.org/10.1177/1076029619890423openalex-snapshot

Performance of the LumiraDx Platform INR Test in an Anticoagulation Clinic Point-of-Care Setting Compared With an Established Laboratory Reference Method

inferred← citeshttps://doi.org/10.1182/blood.2021014835openalex-snapshot

How I approach the prevention and treatment of thrombotic complications in hospitalized patients

inferred← citeshttps://doi.org/10.1186/s12933-022-01581-xopenalex-snapshot

Managing thrombotic risk in patients with diabetes

inferred← citeshttps://doi.org/10.1186/s12959-021-00351-1openalex-snapshot

The impact on renal function after long-term use of anticoagulants in atrial fibrillation patients

inferred← citeshttps://doi.org/10.12659/ajcr.917492openalex-snapshot

Rivaroxaban-Induced Acute Interstitial Nephritis: A Case Report

inferred← citeshttps://doi.org/10.12775/jehs.2024.68.49539openalex-snapshot

Anticoagulants - The Past, The Present, The Future - A Systematic Review

inferred← citeshttps://doi.org/10.17816/mechnikov201911179-92openalex-snapshot

The effect of warfarin, heparin, and modern directly acting oral anticoagulants (dabigatran etexilate, rivaroxaban, apixaban) on the level of coagulation factors: V, VII, VIII, IX, XII, WF

inferred← citeshttps://doi.org/10.18087/cardio.2020.4.n1023openalex-snapshot

Stroke Prevention in Patients with Atrial Fibrillation in Real Clinical Practice, Emphasis on Efficacy and Safety of Anticoagulant Therapy

inferred← citeshttps://doi.org/10.18087/cardio.2021.10.n1767openalex-snapshot

Features of anticoagulant therapy of atrial fibrillation in combination with impaired renal function

inferred← citeshttps://doi.org/10.2147/clep.s383996openalex-snapshot

Acute Kidney Injury in Patients with Non-Valvular Atrial Fibrillation Treated with Rivaroxaban or Warfarin: A Population-Based Study from the United Kingdom

inferred← citeshttps://doi.org/10.2174/0127724328317631240925051326openalex-snapshot

Bleeding vs Thrombosis: Treatment Strategy for Women Having Large Uterine Fibroids and DVT

inferred← citeshttps://doi.org/10.2217/pgs-2017-0207openalex-snapshot

Genotype-Guided Warfarin Therapy: Current Status

inferred← citeshttps://doi.org/10.2217/pgs-2022-0106openalex-snapshot

Impact of CYP2C19 Gene Polymorphisms on Warfarin Dose Requirement: A Systematic Review and Meta-Analysis

inferred← citeshttps://doi.org/10.23736/s2724-5683.22.05891-4openalex-snapshot

The connubium among diabetes, chronic kidney disease and atrial fibrillation

inferred← citeshttps://doi.org/10.26481/dis.20190418fpopenalex-snapshot

The snowball effect in aortic valve disease

inferred← citeshttps://doi.org/10.26481/dis.20200708rgopenalex-snapshot

Oral anticoagulants as double-edged swords

inferred← citeshttps://doi.org/10.26481/dis.20201002ajopenalex-snapshot

Key role for VSMCs in vascular remodeling and calcification

inferred← citeshttps://doi.org/10.26481/dis.20201102ppopenalex-snapshot

Role of vascular remodeling in atherosclerosis and aortic aneurysm

inferred← citeshttps://doi.org/10.31434/rms.v5i2.365openalex-snapshot

Historia de los anticoagulantes y su uso clínico en el presente

inferred← citeshttps://doi.org/10.33590/emjcardiol/10313737openalex-snapshot

The Bigger Picture in Stroke Prevention and Anticoagulation: Think Beyond Atrial Fibrillation

inferred← citeshttps://doi.org/10.3389/fcvm.2022.1052521openalex-snapshot

Clinical significance of the series of CYP2C9*non3 variants, an unignorable predictor of warfarin sensitivity in Chinese population

inferred← citeshttps://doi.org/10.3389/fcvm.2022.938567openalex-snapshot

Vitamin K antagonists and cardiovascular calcification: A systematic review and meta-analysis

inferred← citeshttps://doi.org/10.3389/fmed.2018.00281openalex-snapshot

Structure of Coagulation Factor II: Molecular Mechanism of Thrombin Generation and Development of Next-Generation Anticoagulants

inferred← citeshttps://doi.org/10.3389/fneur.2019.00239openalex-snapshot

The Relationships Between Vitamin K and Cognition: A Review of Current Evidence

inferred← citeshttps://doi.org/10.3389/fphar.2018.00542openalex-snapshot

Association Between ABCB1 Polymorphism and Stable Warfarin Dose Requirements in Brazilian Patients

inferred← citeshttps://doi.org/10.3389/fphar.2026.1685101openalex-snapshot

Rivaroxaban versus warfarin: differential effects on oxidative stress and fibrinolytic markers in atrial fibrillation

inferred← citeshttps://doi.org/10.3389/fphar.2026.1770826openalex-snapshot

Age and gender disparities in oral anticoagulant use: a nine-year nationwide drug utilization analysis

inferred← citeshttps://doi.org/10.3390/cells10040773openalex-snapshot

The Effects of Warfarin and Direct Oral Anticoagulants on Systemic Vascular Calcification: A Review

inferred← citeshttps://doi.org/10.3390/ijms20040896openalex-snapshot

Vitamin K: Double Bonds beyond Coagulation Insights into Differences between Vitamin K1 and K2 in Health and Disease

inferred← citeshttps://doi.org/10.3390/ijms22073692openalex-snapshot

Astragalin Inhibits Cigarette Smoke-Induced Pulmonary Thrombosis and Alveolar Inflammation and Disrupts PAR Activation and Oxidative Stress-Responsive MAPK-Signaling

inferred← citeshttps://doi.org/10.3390/ijms25116099openalex-snapshot

Michael Acceptors as Anti-Cancer Compounds: Coincidence or Causality?

inferred← citeshttps://doi.org/10.3390/jcm14092914openalex-snapshot

Challenges and Opportunities of Direct Oral Anticoagulant (DOAC) Therapy in Complex Clinical Scenarios: A Comprehensive Review and Practical Guide

inferred← citeshttps://doi.org/10.3390/medicina62030532openalex-snapshot

Comparative Renal Outcomes and Effectiveness of Non-Vitamin K Antagonist Oral Anticoagulants Versus Warfarin in Nonvalvular Atrial Fibrillation: Insights from Real-World Data

inferred← citeshttps://doi.org/10.3390/nu10040415openalex-snapshot

Is Matrix Gla Protein Associated with Vascular Calcification? A Systematic Review

inferred← citeshttps://doi.org/10.3390/nu12010138openalex-snapshot

Vitamin K as a Diet Supplement with Impact in Human Health: Current Evidence in Age-Related Diseases

inferred← citeshttps://doi.org/10.3390/nu16121798openalex-snapshot

Vitamin K for Vascular Calcification in Kidney Patients: Still Alive and Kicking, but Still a Lot to Learn

inferred← citeshttps://doi.org/10.33963/kp.a2021.0021openalex-snapshot

Laboratory assessment of the direct oral anticoagulants: who can benefit?

inferred← citeshttps://doi.org/10.34172/japid.2023.020openalex-snapshot

Effect of direct oral anticoagulant dabigatran on early bone healing: An experimental study in rats

inferred← citeshttps://doi.org/10.34172/jnp.2022.17343openalex-snapshot

Case report: rivaroxaban related nephropathy

inferred← citeshttps://doi.org/10.36290/kar.2018.047openalex-snapshot

Anticoagulation therapy 2018

inferred← citeshttps://doi.org/10.36290/vnl.2017.175openalex-snapshot

The current role of warfarin

inferred← citeshttps://doi.org/10.4172/2161-0509.1000192openalex-snapshot

New Perspectives for the Nutritional Value of Vitamin K in Human Health

inferred← citeshttps://doi.org/10.4172/2329-9517.1000245openalex-snapshot

Gla-rich Protein (GRP): A New Player In The Burden Of Vascular Calcification

inferred← citeshttps://doi.org/10.5649/jjphcs.48.419openalex-snapshot

Examination of the Bleeding Risk Involved in the Concomitant Use of Antidepressants and Direct Oral Anticoagulants

inferred← citeshttps://doi.org/10.6084/m9.figshare.17162852openalex-snapshot

Additional file 1 of The impact on renal function after long-term use of anticoagulants in atrial fibrillation patients

inferred← citeshttps://doi.org/10.70675/b18e050bz2ad0z4e29z87ddzc8ed910b9f04openalex-snapshot

Etude de la tératogenicité des anticoagulants antivitamine K : nécessité de rechercher de nouvelles cibles anticoagulantes : la piste du partenaire protéique d’activation de VKORC1

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