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Behavioral, Anti-Inflammatory, and Neuroprotective Effects of a Novel FPR2 Agonist in Two Mouse Models of Autism

https://doi.org/10.3390/ph15020161

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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The N-Formyl Peptide Receptor 2 (FPR2) Agonist MR-39 Improves Ex Vivo and In Vivo Amyloid Beta (1–42)-Induced Neuroinflammation in Mouse Models of Alzheimer’s Disease

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Nrf2 activator, sulforaphane ameliorates autism-like symptoms through suppression of Th17 related signaling and rectification of oxidant-antioxidant imbalance in periphery and brain of BTBR T+tf/J mice

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Microglial Activation and Increased Microglial Density Observed in the Dorsolateral Prefrontal Cortex in Autism

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Citalopram attenuates social behavior deficits in the BTBR T+Itpr3tf/J mouse model of autism

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On the Dependency of Cellular Protein Levels on mRNA Abundance

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Novel ureidopropanamide based N-formyl peptide receptor 2 (FPR2) agonists with potential application for central nervous system disorders characterized by neuroinflammation

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Elevated immune response in the brain of autistic patients

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Peripheral and central inflammation in autism spectrum disorders

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A Synaptic Perspective of Fragile X Syndrome and Autism Spectrum Disorders

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AMPAKINE enhancement of social interaction in the BTBR mouse model of autism

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The serotonin receptor 7 promotes neurite outgrowth via ERK and Cdk5 signaling pathways

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Beneficial Effects of Fingolimod on Social Interaction, CNS and Peripheral Immune Response in the BTBR Mouse Model of Autism

inferredcites →https://doi.org/10.1016/j.ntt.2013.01.004openalex-snapshot

In utero exposure to valproic acid and autism — A current review of clinical and animal studies

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Anti-inflammatory circuitry: Lipoxin, aspirin-triggered lipoxins and their receptor ALX

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Lipoxin A4 biology in the human synovium. Role of the ALX signaling pathways in modulation of inflammatory arthritis

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Pleiotropic roles of formyl peptide receptors

inferredcites →https://doi.org/10.1017/s1461145711001714openalex-snapshot

Autism-like behaviours with transient histone hyperacetylation in mice treated prenatally with valproic acid

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Vortioxetine Reduces Marble Burying but Only Transiently Enhances Social Interaction Preference in Adult Male BTBR T+Itpr3tf/J Mice

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Resolution of inflammation: the beginning programs the end

inferredcites →https://doi.org/10.1038/nm.2123openalex-snapshot

Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions

inferredcites →https://doi.org/10.1038/nm1355openalex-snapshot

Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependent

inferredcites →https://doi.org/10.1038/s41386-018-0098-5openalex-snapshot

Pharmacological modulation of AMPA receptor rescues social impairments in animal models of autism

inferredcites →https://doi.org/10.1038/sj.npp.1300518openalex-snapshot

Behavioral Alterations in Rats Prenatally Exposed to Valproic Acid: Animal Model of Autism

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inferredcites →https://doi.org/10.1046/j.0021-9630.2003.00317.xopenalex-snapshot

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Single administration of resveratrol improves social behavior in adult mouse models of autism spectrum disorder

inferredcites →https://doi.org/10.1084/jem.20061826openalex-snapshot

Lipoxins and aspirin-triggered lipoxin inhibit inflammatory pain processing

inferredcites →https://doi.org/10.1089/cap.2015.0166openalex-snapshot

Abnormal Mechanisms of Plasticity and Metaplasticity in Autism Spectrum Disorders and Fragile X Syndrome

inferredcites →https://doi.org/10.1093/med/9780199696758.003.0214openalex-snapshot

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inferredcites →https://doi.org/10.1097/mop.0000000000000278openalex-snapshot

Genetic research in autism spectrum disorders

inferredcites →https://doi.org/10.1097/wnr.0000000000000350openalex-snapshot

Decreased plasma levels of lipoxin A4 in children with autism spectrum disorders

inferredcites →https://doi.org/10.1100/tsw.2010.113openalex-snapshot

Lipoxin and Aspirin-Triggered Lipoxins

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Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7

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Lipoxin A 4 suppresses the development of endometriosis in an ALX receptor‐dependent manner via the p38 MAPK pathway

inferredcites →https://doi.org/10.1111/j.1469-7610.2006.01594.xopenalex-snapshot

Social‐cognition and the broad autism phenotype: identifying genetically meaningful phenotypes

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The precursor of resolvin D series and aspirin-triggered resolvin D1 display anti-hyperalgesic properties in adjuvant-induced arthritis in rats

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Autism‐like behavioral phenotypes in BTBR T+tf/J mice

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Serotonin 5‐ HT 7 receptor increases the density of dendritic spines and facilitates synaptogenesis in forebrain neurons

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Differential Activation of Formyl Peptide Receptor Signaling by Peptide Ligands

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The Lipoxin Receptor ALX: Potent Ligand-Specific and Stereoselective Actions in Vivo

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Resolution Phase of Inflammation: Novel Endogenous Anti-Inflammatory and Proresolving Lipid Mediators and Pathways

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Effect of enriching the diet with menhaden oil or daily treatment with resolvin D1 on neuropathy in a mouse model of type 2 diabetes

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Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

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Aberrant Immune Responses in a Mouse with Behavioral Disorders

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G-Protein Coupled Receptors Involved in the Resolution of Inflammation: Ligands and Therapeutic Perspectives

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Novel Anti-Inflammatory-Pro-Resolving Mediators and Their Receptors

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The Contribution of Formyl Peptide Receptor Dysfunction to the Course of Neuroinflammation: A Potential Role in the Brain Pathology

inferredcites →https://doi.org/10.3389/fnbeh.2015.00062openalex-snapshot

Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamics

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Relevance of Neuroinflammation and Encephalitis in Autism

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What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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