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Novel Bile Salt Stabilized Vesicles-Mediated Effective Topical Delivery of Diclofenac Sodium: A New Therapeutic Approach for Pain and Inflammation

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/jps.2600521210openalex-snapshot
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
inferredcites →https://doi.org/10.1007/s00210-021-02139-6openalex-snapshot
Diclofenac down-regulates COX-2 induced expression of CD44 and ICAM-1 in human HT29 colorectal cancer cells
inferredcites →https://doi.org/10.1007/s10753-013-9705-0openalex-snapshot
RETRACTED ARTICLE: Release-Active Dilutions of Diclofenac Enhance Anti-inflammatory Effect of Diclofenac in Carrageenan-Induced Rat Paw Edema Model
inferredcites →https://doi.org/10.1007/s10787-013-0175-7openalex-snapshot
The anti-inflammatory effect of diclofenac is considerably augmented by topical capsaicinoids-containing patch in carrageenan-induced paw oedema of rat
inferredcites →https://doi.org/10.1007/s10787-020-00688-5openalex-snapshot
RETRACTED ARTICLE: Polystichum braunii extracts inhibit Complete Freund’s adjuvant-induced arthritis via upregulation of I-κB, IL-4, and IL-10, downregulation of COX-2, PGE2, IL-1β, IL-6, NF-κB, and TNF-α, and subsiding oxidative stress
inferredcites →https://doi.org/10.1007/s10787-020-00761-zopenalex-snapshot
Asphodelus tenuifolius extracts arrested inflammation and arthritis through modulation of TNF-α, NF-κB, ILs, and COX-2 activities in in vivo models
inferredcites →https://doi.org/10.1007/s10856-015-5496-1openalex-snapshot
Macrophage response to chitosan/poly-(γ-glutamic acid) nanoparticles carrying an anti-inflammatory drug
inferredcites →https://doi.org/10.1007/s10856-021-06547-1openalex-snapshot
Hydrogels in the treatment of rheumatoid arthritis: drug delivery systems and artificial matrices for dynamic in vitro models
inferredcites →https://doi.org/10.1007/s12011-021-02784-1openalex-snapshot
Activated Nrf-2 Pathway by Vitamin E to Attenuate Testicular Injuries of Rats with Sub-chronic Cadmium Exposure
inferredcites →https://doi.org/10.1007/s13346-019-00688-1openalex-snapshot
A novel nanogel loaded with chitosan decorated bilosomes for transdermal delivery of terbutaline sulfate: artificial neural network optimization, in vitro characterization and in vivo evaluation
inferredcites →https://doi.org/10.1007/s13596-020-00502-1openalex-snapshot
Anti-inflammatory activity of Xanthium indicum on carrageenan-induced paw edema in rats
inferredcites →https://doi.org/10.1016/0378-5173(94)90228-3openalex-snapshot
Preparation and properties of vesicles (niosomes) of sorbitan monoesters (Span 20, 40, 60 and 80) and a sorbitan triester (Span 85)
inferredcites →https://doi.org/10.1016/j.bbadis.2021.166322openalex-snapshot
The spike protein of SARS-CoV-2 induces heme oxygenase-1: Pathophysiologic implications
inferredcites →https://doi.org/10.1016/j.bcp.2020.114147openalex-snapshot
Non-steroidal anti-inflammatory drugs (NSAIDs) and organ damage: A current perspective
inferredcites →https://doi.org/10.1016/j.biomaterials.2004.02.020openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.biopha.2021.111880openalex-snapshot
Topical nanocarriers for management of Rheumatoid Arthritis: A review
inferredcites →https://doi.org/10.1016/j.carres.2009.01.011openalex-snapshot
Synthesis and characterization of chitosan-based pH-sensitive semi-interpenetrating network microspheres for controlled release of diclofenac sodium
inferredcites →https://doi.org/10.1016/j.ddtec.2005.05.003openalex-snapshot
Vesicles as a tool for transdermal and dermal delivery
inferredcites →https://doi.org/10.1016/j.ijbiomac.2013.01.015openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.ijpharm.2009.04.022openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.ijpharm.2010.06.034openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.ijpharm.2013.11.028openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.ijpharm.2014.06.041openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.ijpharm.2015.03.033openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.ijpharm.2017.05.029openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.ijpharm.2021.121244openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.jconrel.2008.12.018openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.jddst.2018.02.003openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.jddst.2020.102110openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.jpain.2013.01.683openalex-snapshot
Topical diclofenac in the treatment of post-incisional neuropathic pain: case report
inferredcites →https://doi.org/10.1016/j.jpain.2013.06.008openalex-snapshot
An Overview of Animal Models of Pain: Disease Models and Outcome Measures
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inferredcites →https://doi.org/10.1016/j.matpr.2017.07.273openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.solidstatesciences.2012.01.016openalex-snapshot
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inferredcites →https://doi.org/10.1038/s41577-020-00491-xopenalex-snapshot
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inferredcites →https://doi.org/10.1038/s41598-017-16041-wopenalex-snapshot
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inferredcites →https://doi.org/10.1038/s41598-018-22913-6openalex-snapshot
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inferredcites →https://doi.org/10.1074/jbc.m110.138636openalex-snapshot
Ethanol-induced HO-1 and NQO1 Are Differentially Regulated by HIF-1α and Nrf2 to Attenuate Inflammatory Cytokine Expression
inferredcites →https://doi.org/10.1080/03639045.2016.1268153openalex-snapshot
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inferredcites →https://doi.org/10.1080/03639045.2019.1601737openalex-snapshot
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inferredcites →https://doi.org/10.1080/08982104.2018.1430831openalex-snapshot
Investigating superiority of novel bilosomes over niosomes in the transdermal delivery of diacerein:in vitrocharacterization,ex vivopermeation andin vivoskin deposition study
inferredcites →https://doi.org/10.1080/08982104.2018.1524482openalex-snapshot
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inferredcites →https://doi.org/10.1080/08982104.2020.1867166openalex-snapshot
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inferredcites →https://doi.org/10.1080/1061186x.2019.1650053openalex-snapshot
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inferredcites →https://doi.org/10.1080/1061186x.2020.1817041openalex-snapshot
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inferredcites →https://doi.org/10.1080/10717544.2018.1477858openalex-snapshot
Novel in situ gelling vaginal sponges of sildenafil citrate-based cubosomes for uterine targeting
inferredcites →https://doi.org/10.1080/10717544.2019.1686087openalex-snapshot
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inferredcites →https://doi.org/10.1080/10717544.2022.2044938openalex-snapshot
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inferredcites →https://doi.org/10.1080/21553769.2013.879925openalex-snapshot
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inferredcites →https://doi.org/10.1089/ars.2020.8124openalex-snapshot
The Interplay Between Systemic Inflammation, Oxidative Stress, and Tissue Remodeling in Tuberculosis
inferredcites →https://doi.org/10.1106/gx1t-2jc6-qwc6-69gcopenalex-snapshot
Polymers for Use in Controlled Release Systems: The Effect of Surfactants on their Swelling Properties
inferredcites →https://doi.org/10.1111/j.1476-5381.1963.tb01508.xopenalex-snapshot
CHEMOTHERAPY OF ARTHRITIS INDUCED IN RATS BY MYCOBACTERIAL ADJUVANT
inferredcites →https://doi.org/10.1111/pme.12110openalex-snapshot
Topical Diclofenac Treatment for Post-Incisional Neuropathic Pain
inferredcites →https://doi.org/10.1155/2020/4071818openalex-snapshot
Improved Analgesic and Anti-Inflammatory Effect of Diclofenac Sodium by Topical Nanoemulgel: Formulation Development—In VitroandIn VivoStudies
inferredcites →https://doi.org/10.1155/2020/8508906openalex-snapshot
Diallyl Disulfide Suppresses Inflammatory and Oxidative Machineries following Carrageenan Injection-Induced Paw Edema in Mice
inferredcites →https://doi.org/10.1155/2021/5583215openalex-snapshot
Reactive Oxygen Species as a Link between Antioxidant Pathways and Autophagy
inferredcites →https://doi.org/10.1158/1055-9965.epi-14-0064openalex-snapshot
A Review of the Application of Inflammatory Biomarkers in Epidemiologic Cancer Research
inferredcites →https://doi.org/10.1159/000452591openalex-snapshot
Triptolide Attenuates Inflammatory Response in Membranous Glomerulo-Nephritis Rat via Downregulation of NF-κB Signaling Pathway
inferredcites →https://doi.org/10.1177/15593258221103846openalex-snapshot
Effect of Diclofenac and Andrographolide Combination on Carrageenan-Induced Paw Edema and Hyperalgesia in Rats
inferredcites →https://doi.org/10.1208/pt070367openalex-snapshot
Thermoreversible-mucoadhesive Gel for nasal delivery of sumatriptan
inferredcites →https://doi.org/10.1208/s12249-008-9105-1openalex-snapshot
Niosome-Encapsulated Gentamicin for Ophthalmic Controlled Delivery
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inferredcites →https://doi.org/10.1208/s12249-015-0440-8openalex-snapshot
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inferredcites →https://doi.org/10.1208/s12249-018-1019-yopenalex-snapshot
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inferredcites →https://doi.org/10.1208/s12249-019-1306-2openalex-snapshot
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inferredcites →https://doi.org/10.1208/s12249-020-01656-6openalex-snapshot
Novel Enhanced Therapeutic Efficacy of Dapoxetine HCl by Nano-Vesicle Transdermal Gel for Treatment of Carrageenan-Induced Rat Paw Edema
inferredcites →https://doi.org/10.1248/bpb.b18-00979openalex-snapshot
Olive-Derived Hydroxytyrosol Shows Anti-inflammatory Effect without Gastric Damage in Rats
inferredcites →https://doi.org/10.1371/journal.pone.0153015openalex-snapshot
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inferredcites →https://doi.org/10.1517/17425247.2012.686490openalex-snapshot
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inferredcites →https://doi.org/10.2147/ijn.s278688openalex-snapshot
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inferredcites →https://doi.org/10.2147/ijn.s345505openalex-snapshot
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inferredcites →https://doi.org/10.3109/08982104.2014.941861openalex-snapshot
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inferredcites →https://doi.org/10.3109/10717544.2014.923958openalex-snapshot
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inferredcites →https://doi.org/10.3390/nano10122472openalex-snapshot
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inferredcites →https://doi.org/10.3390/ph15030282openalex-snapshot
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inferredcites →https://doi.org/10.3390/pharmaceutics12090855openalex-snapshot
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inferredcites →https://doi.org/10.3390/pharmaceutics14030563openalex-snapshot
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inferredcites →https://doi.org/10.3390/pharmaceutics14040875openalex-snapshot
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inferredcites →https://doi.org/10.3892/ijmm.2016.2809openalex-snapshot
Luteolin protects mice from severe acute pancreatitis by exerting HO-1-mediated anti-inflammatory and antioxidant effects
inferredcites →https://doi.org/10.4103/0975-7406.92724openalex-snapshot
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inferredcites →https://doi.org/10.5152/eurasianjmed.2018.0010openalex-snapshot
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What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.3897/pharmacia.71.e116917zenodo-depositor-declared
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inferred← citeshttps://doi.org/10.1007/s10787-025-01802-1openalex-snapshot
RETRACTED ARTICLE: Phytochemical studies of Veitchia arecina Becc. leaves with evaluation of in-vitro, in-vivo anti-inflammatory, and wound healing properties in rats
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inferred← citeshttps://doi.org/10.1016/j.apsb.2023.05.025openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.ijpharm.2023.122776openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.ijpharm.2025.125700openalex-snapshot
Role of chitosan coated invasomes in enhancement of transdermal delivery of tenoxicam for management of osteoarthritis: In vitro characterization, statistical optimization, ex vivo, and in vivo assessments
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Exploitation of transdermal nanobilosomal gel platforms for ameliorating anti-diabetic activity of empagliflozin following I-optimal design
inferred← citeshttps://doi.org/10.1016/j.jddst.2024.105395openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.jddst.2025.107193openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.jddst.2026.108542openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.onano.2025.100255openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.onano.2025.100265openalex-snapshot
Quality by design of ultra deformable nanovesicles loaded with flunarizine for brain targeting utilizing risk assessment and multivariate analytical methods
inferred← citeshttps://doi.org/10.1016/j.sajb.2023.09.046openalex-snapshot
Pegylated bilosomes for improvement of oral delivery of Biochanin A: Development to preclinical evaluation
inferred← citeshttps://doi.org/10.1021/acsomega.4c01133openalex-snapshot
Tailoring of Bilosomal Nanogel for Augmenting the Off-Label Use of Sildenafil Citrate in Pediatric Pulmonary Hypertension
inferred← citeshttps://doi.org/10.1080/02652048.2024.2423618openalex-snapshot
Dermal drug delivery via bilosomes: a synergistic integration for better therapeutic outcomes
inferred← citeshttps://doi.org/10.1080/03639045.2023.2256404openalex-snapshot
Breaking barriers: bilosomes gel potentials to pave the way for transdermal breast cancer treatment with Tamoxifen
inferred← citeshttps://doi.org/10.1080/08982104.2026.2614785openalex-snapshot
Development of ganciclovir/resveratrol coloaded bilosomes for improvement of ophthalmic delivery and therapeutic efficacy
inferred← citeshttps://doi.org/10.1080/08982104.2026.2616857openalex-snapshot
Enhanced buccal bioavailability of olmesartan through ultradeformable bilosomes loaded film: a novel approach for hypertension management
inferred← citeshttps://doi.org/10.1080/10837450.2025.2611896openalex-snapshot
Galactosylated bilosomes for liver-targeted delivery of ledipasvir: optimization, conjugate synthesis, and cellular evaluation
inferred← citeshttps://doi.org/10.1080/20415990.2025.2469488openalex-snapshot
Drug delivery systems incorporating bile salts: advancements since the conception of bilosomes
inferred← citeshttps://doi.org/10.1080/20415990.2025.2527578openalex-snapshot
Luliconazole bilosomal gel for treating fungal infection: development, optimization and antifungal activity
inferred← citeshttps://doi.org/10.1208/s12249-024-02823-9openalex-snapshot
Assembly of In-Situ Gel Containing Nano-Spanlastics of an Angiotensin II Inhibitor as a Novel Epitome for Hypertension Management: Factorial Design Optimization, In-vitro Gauging, Pharmacokinetics, and Pharmacodynamics Appraisal
inferred← citeshttps://doi.org/10.1208/s12249-025-03097-5openalex-snapshot
RETRACTED ARTICLE: Nasal In-Situ Gels of Brij®-Enriched Novasomes as Optimistic Nanovesicular Carriers for Enhancing Anti-Depressant Action of Agomelatine
inferred← citeshttps://doi.org/10.1208/s12249-026-03390-xopenalex-snapshot
Dapagliflozin Loaded Bilosomes Gel for Transdermal Delivery: Formulation, Optimization, Physicochemical Characterization, and In Vivo Evaluation
inferred← citeshttps://doi.org/10.1922/pjs.16.4s.2026.633openalex-snapshot
Naringenin Loaded topical Nano bilosome formulation in-vitro Characterization and optimization using Box-Behnken Design
inferred← citeshttps://doi.org/10.2174/1872210518666230905155459openalex-snapshot
Nano-based Therapeutics for Rheumatoid Arthritis: Recent Patents and Development
inferred← citeshttps://doi.org/10.3390/gels10040239openalex-snapshot
The Exploitation of Sodium Deoxycholate-Stabilized Nano-Vesicular Gel for Ameliorating the Antipsychotic Efficiency of Sulpiride
inferred← citeshttps://doi.org/10.3390/gels12020156openalex-snapshot
Exploring the Potential of Transdermal Nanobilosomal Gel for Magnified Anti-Inflammatory Efficacy of Thymol for Managing Rheumatoid Arthritis
inferred← citeshttps://doi.org/10.3390/gels9040322openalex-snapshot
Formulation Development, Optimization by Box–Behnken Design, and In Vitro and Ex Vivo Characterization of Hexatriacontane-Loaded Transethosomal Gel for Antimicrobial Treatment for Skin Infections
inferred← citeshttps://doi.org/10.3390/md21070394openalex-snapshot
Chitosan/Virgin-Coconut-Oil-Based System Enriched with Cubosomes: A 3D Drug-Delivery Approach
inferred← citeshttps://doi.org/10.3390/molecules30051181openalex-snapshot
The Pharmaceutical and Pharmacological Potential Applications of Bilosomes as Nanocarriers for Drug Delivery
inferred← citeshttps://doi.org/10.3390/pharmaceutics15020581openalex-snapshot
Formulation of Miconazole-Loaded Chitosan–Carbopol Vesicular Gel: Optimization to In Vitro Characterization, Irritation, and Antifungal Assessment
inferred← citeshttps://doi.org/10.3390/pharmaceutics16010090openalex-snapshot
Cross-Linked Alginate Dialdehyde/Chitosan Hydrogel Encompassing Curcumin-Loaded Bilosomes for Enhanced Wound Healing Activity
inferred← citeshttps://doi.org/10.3390/pharmaceutics16060697openalex-snapshot
Emerging Trends in Bilosomes as Therapeutic Drug Delivery Systems
inferred← citeshttps://doi.org/10.3390/polym15030677openalex-snapshot
Tailoring of Novel Bile Salt Stabilized Vesicles for Enhanced Transdermal Delivery of Simvastatin: A New Therapeutic Approach against Inflammation
inferred← citeshttps://doi.org/10.3390/polysaccharides7030078openalex-snapshot
Chitosan-Modified Nanobilosomal Gel for the Transdermal Delivery of Thymol and Silibinin for Rheumatoid Arthritis Management: Synergistic Effect and Improved In Vivo Articular Restoration
inferred← citeshttps://doi.org/10.34172/apb.2024.057openalex-snapshot
Development of Gentamicin Bilosomes Laden In Situ Gel for Topical Ocular Delivery: Optimization, In Vitro Characterization, Toxicity, and Anti-microbial Evaluation
inferred← citeshttps://doi.org/10.54133/ajms.v5i.176openalex-snapshot
Effects of Different Types of Bile Salts on the Physical Properties of Ropinirole-Loaded
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