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Application of the Gastrointestinal Simulator (GIS) Coupled with In Silico Modeling to Measure the Impact of Coca-Cola® on the Luminal and Systemic Behavior of Loratadine (BCS Class 2b)

https://doi.org/10.3390/pharmaceutics12060566
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Loratadine: Multiple‐Dose Pharmacokinetics
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Pharmacokinetics and Dose Proportionality of Loratadine
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Excretion of Loratadine in Human Breast Milk
inferredcites →https://doi.org/10.1002/jps.23892openalex-snapshot
Toward an Improved Understanding of the Precipitation Behavior of Weakly Basic Drugs from Oral Lipid-Based Formulations
inferredcites →https://doi.org/10.1007/s002280050280openalex-snapshot
Influence of an acidic beverage (Coca-Cola) on the absorption of itraconazole
inferredcites →https://doi.org/10.1007/s11095-012-0759-8openalex-snapshot
pH-Induced Precipitation Behavior of Weakly Basic Compounds: Determination of Extent and Duration of Supersaturation Using Potentiometric Titration and Correlation to Solid State Properties
inferredcites →https://doi.org/10.1016/j.clinthera.2010.02.001openalex-snapshot
A retrospective, open-label analysis of the population pharmacokinetics of a single 10-mg dose of loratadine in healthy white Jordanian male volunteers
inferredcites →https://doi.org/10.1016/j.ejpb.2020.02.014openalex-snapshot
Exploring the impact of real-life dosing conditions on intraluminal and systemic concentrations of atazanavir in parallel with gastric motility recording in healthy subjects
inferredcites →https://doi.org/10.1016/j.ejps.2018.01.039openalex-snapshot
Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro-in silico-in vivo approach
inferredcites →https://doi.org/10.1016/j.ejps.2019.04.003openalex-snapshot
The mechanisms of pharmacokinetic food-drug interactions – A perspective from the UNGAP group
inferredcites →https://doi.org/10.1016/j.ijpharm.2018.06.050openalex-snapshot
Formulation predictive dissolution (fPD) testing to advance oral drug product development: An introduction to the US FDA funded ‘21st Century BA/BE’ project
inferredcites →https://doi.org/10.1016/j.jpba.2005.03.041openalex-snapshot
Simultaneous determination of loratadine and pseudoephedrine sulfate in human plasma by liquid chromatography–electrospray mass spectrometry for pharmacokinetic studies
inferredcites →https://doi.org/10.1016/j.jpba.2006.08.013openalex-snapshot
Determination of loratadine and its active metabolite in human plasma by high-performance liquid chromatography with mass spectrometry detection
inferredcites →https://doi.org/10.1016/j.xphs.2016.05.026openalex-snapshot
Regulatory Considerations of Bioequivalence Studies for Oral Solid Dosage Forms in Japan
inferredcites →https://doi.org/10.1016/j.xphs.2017.03.039openalex-snapshot
The Effect of Sparkling Water on Intraluminal Formulation Behavior and Systemic Drug Performance
inferredcites →https://doi.org/10.1016/s0149-2918(03)80215-1openalex-snapshot
Pharmacokinetic properties of single-dose loratadine and ambroxol alone and combined in tablet formulations in healthy men
inferredcites →https://doi.org/10.1016/s0149-2918(97)80052-5openalex-snapshot
Pharmacokinetics of loratadine and pseudoephedrine following single and multiple doses of once- versus twice-daily combination tablet formulations in healthy adult males
inferredcites →https://doi.org/10.1016/s0378-4347(01)00053-6openalex-snapshot
Determination of loratadine in human plasma by high-performance liquid chromatographic method with ultraviolet detection
inferredcites →https://doi.org/10.1021/acs.molpharmaceut.6b01063openalex-snapshot
Utilization of Gastrointestinal Simulator, an in Vivo Predictive Dissolution Methodology, Coupled with Computational Approach To Forecast Oral Absorption of Dipyridamole
inferredcites →https://doi.org/10.1021/acs.molpharmaceut.7b00426openalex-snapshot
Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs
inferredcites →https://doi.org/10.1021/acs.molpharmaceut.8b00515openalex-snapshot
Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans—Part 1: Fasted State Conditions
inferredcites →https://doi.org/10.1021/acs.molpharmaceut.8b00736openalex-snapshot
Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans—Part 2: Fed State
inferredcites →https://doi.org/10.1021/mp100116gopenalex-snapshot
Use of Artificial Stomach−Duodenum Model for Investigation of Dosing Fluid Effect on Clinical Trial Variability
inferredcites →https://doi.org/10.1021/mp4003249openalex-snapshot
Mechanistic Understanding of the Effect of PPIs and Acidic Carbonated Beverages on the Oral Absorption of Itraconazole Based on Absorption Modeling with Appropriate in Vitro Data
inferredcites →https://doi.org/10.1023/a:1011984216775openalex-snapshot
Dissolution Testing as a Prognostic Tool for Oral Drug Absorption: Immediate Release Dosage Forms
inferredcites →https://doi.org/10.1023/a:1026155822121openalex-snapshot
Comparison of the Rates of Disintegration, Gastric Emptying, and Drug Absorption Following Administration of a New and a Conventional Paracetamol Formulation, Using γ Scintigraphy
inferredcites →https://doi.org/10.1039/c4fo00290copenalex-snapshot
Variations in caffeine and chlorogenic acid contents of coffees: what are we drinking?
inferredcites →https://doi.org/10.1080/00498250701463317openalex-snapshot
Disposition of loratadine in healthy volunteers
inferredcites →https://doi.org/10.1081/ddc-120003449openalex-snapshot
A New Rapidly Absorbed Paracetamol Tablet Containing Sodium Bicarbonate. II. Dissolution Studies and In Vitro/In Vivo Correlation
inferredcites →https://doi.org/10.1093/chromsci/48.1.35openalex-snapshot
LC-MS-ESI for the Determination of Loratadine and Descarboethoxyloratadine in Human Plasma
inferredcites →https://doi.org/10.1111/jcpt.12535openalex-snapshot
Evaluation of real-life dosing of oral medicines with respect to fluid and food intake in a Dutch-speaking population
inferredcites →https://doi.org/10.1128/aac.39.8.1671openalex-snapshot
Effects of an acidic beverage (Coca-Cola) on absorption of ketoconazole
inferredcites →https://doi.org/10.1136/gut.29.3.302openalex-snapshot
Effect of meal temperature on gastric emptying of liquids in man.
inferredcites →https://doi.org/10.1177/030006058801600106openalex-snapshot
The Pharmacokinetics of Loratadine in Normal Geriatric Volunteers
inferredcites →https://doi.org/10.1177/106002808902300601openalex-snapshot
Loratadine: A Nonsedating Antihistamine with Once-Daily Dosing
inferredcites →https://doi.org/10.1177/1078155217692152openalex-snapshot
Pepsi® or Coke®? Influence of acid on dasatinib absorption
inferredcites →https://doi.org/10.1200/jco.2015.65.2560openalex-snapshot
Influence of the Acidic Beverage Cola on the Absorption of Erlotinib in Patients With Non–Small-Cell Lung Cancer
inferredcites →https://doi.org/10.1211/0022357022511openalex-snapshot
Predicting the precipitation of poorly soluble weak bases upon entry in the small intestine
inferredcites →https://doi.org/10.1248/bpb.27.1630openalex-snapshot
Classification of Loratadine Based on the Biopharmaceutics Drug Classification Concept and Possible in Vitro-in Vivo Correlation
inferredcites →https://doi.org/10.1358/mf.2002.24.1.677125openalex-snapshot
Effect of an acidic beverage (Coca-Cola) on the pharmacokinetics of carbamazepine in healthy volunteers
inferredcites →https://doi.org/10.2165/11592630-000000000-00000openalex-snapshot
Effect of pH and Comedication on Gastrointestinal Absorption of Posaconazole
inferredcites →https://doi.org/10.4196/kjpp.2017.21.1.107openalex-snapshot
Prediction of pharmacokinetics and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach: A case study of caffeine and ciprofloxacin

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4625721openalex-extracted
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2021.120958openalex-snapshot
Biorelevant dissolution testing and physiologically based absorption modeling to predict in vivo performance of supersaturating drug delivery systems
inferred← citeshttps://doi.org/10.1016/j.jcou.2024.102884openalex-snapshot
Valorization of large-scale supply of carbonated water: A review
inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.1c00262openalex-snapshot
Improving Dissolution Behavior and Oral Absorption of Drugs with pH-Dependent Solubility Using pH Modifiers: A Physiologically Realistic Mass Transport Analysis
inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.2c00292openalex-snapshot
Antiallergic Treatment of Bariatric Patients: Potentially Hampered Solubility/Dissolution and Bioavailability of Loratadine, but Not Desloratadine, Post-Bariatric Surgery
inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.2c00490openalex-snapshot
Development of an In Vitro System To Emulate an In Vivo Subcutaneous Environment: Small Molecule Drug Assessment
inferred← citeshttps://doi.org/10.3390/gels7040243openalex-snapshot
Ambroxol Hydrochloride Loaded Gastro-Retentive Nanosuspension Gels Potentiate Anticancer Activity in Lung Cancer (A549) Cells
inferred← citeshttps://doi.org/10.3390/liquids5040034openalex-snapshot
In-Vitro Dissolution Profile Comparison of Fixed Dose Combination Suspension Containing Ibuprofen and Loratadine with Their Corresponding Marketed Suspensions
inferred← citeshttps://doi.org/10.3390/molecules28196962openalex-snapshot
Revisiting Supersaturation of a Biopharmaceutical Classification System IIB Drug: Evaluation via a Multi-Cup Dissolution Approach and Molecular Dynamic Simulation
inferred← citeshttps://doi.org/10.3390/pharmaceutics12121137openalex-snapshot
Erratum: Hens, B.; et al. Application of the Gastrointestinal Simulator (GIS) Coupled with In Silico Modeling to Measure the Impact of Coca-Cola® on the Luminal and Systemic Behavior of Loratadine (BCS Class 2b). Pharmaceutics, 2020, 12, 566
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