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Disordered Mechanical Stress and Tissue Engineering Therapies in Intervertebral Disc Degeneration

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Outgoing claims: the papers this work cites, builds on, or argues with.

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In vivo remodeling of intervertebral discs in response to short‐ and long‐term dynamic compression

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Mechanosensitive ion channels in nonspecialized cells

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Single lamellar mechanics of the human lumbar anulus fibrosus

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Decellularized bovine intervertebral disc as a natural scaffold for xenogenic cell studies

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In situ forming hydrogels composed of oxidized high molecular weight hyaluronic acid and gelatin for nucleus pulposus regeneration

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Photochemically crosslinked collagen annulus plug: A potential solution solving the leakage problem of cell-based therapies for disc degeneration

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Injectable hydrogels with high fixed charge density and swelling pressure for nucleus pulposus repair: Biomimetic glycosaminoglycan analogues

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Photocrosslinkable laminin-functionalized polyethylene glycol hydrogel for intervertebral disc regeneration

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Translation of an engineered nanofibrous disc-like angle-ply structure for intervertebral disc replacement in a small animal model

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Riboflavin crosslinked high-density collagen gel for the repair of annular defects in intervertebral discs: An in vivo study

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Modulation of the gene expression of annulus fibrosus-derived stem cells using poly(ether carbonate urethane)urea scaffolds of tunable elasticity

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Mechanical restoration and failure analyses of a hydrogel and scaffold composite strategy for annulus fibrosus repair

inferredcites →https://doi.org/10.1016/j.actbio.2016.09.033openalex-snapshot

Self-assembling peptide hydrogel for intervertebral disc tissue engineering

inferredcites →https://doi.org/10.1016/j.actbio.2017.04.019openalex-snapshot

Regulation of human nucleus pulposus cells by peptide-coupled substrates

inferredcites →https://doi.org/10.1016/j.bbamcr.2009.01.012openalex-snapshot

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inferredcites →https://doi.org/10.1016/j.bbrc.2005.08.128openalex-snapshot

Strain-controlled enzymatic cleavage of collagen in loaded matrix

inferredcites →https://doi.org/10.1016/j.bbrc.2008.05.044openalex-snapshot

Vascular endothelial growth factor-A is a survival factor for nucleus pulposus cells in the intervertebral disc

inferredcites →https://doi.org/10.1016/j.biomaterials.2010.03.078openalex-snapshot

Intervertebral disc regeneration after implantation of a cell-free bioresorbable implant in a rabbit disc degeneration model

inferredcites →https://doi.org/10.1016/j.biomaterials.2013.06.038openalex-snapshot

Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration

inferredcites →https://doi.org/10.1016/j.biomaterials.2014.11.049openalex-snapshot

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inferredcites →https://doi.org/10.1016/j.biomaterials.2016.01.040openalex-snapshot

Polyurethane scaffold with in situ swelling capacity for nucleus pulposus replacement

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A photopolymerized composite hydrogel and surgical implanting tool for a nucleus pulposus replacement

inferredcites →https://doi.org/10.1016/j.biomaterials.2017.03.013openalex-snapshot

Biomaterials for intervertebral disc regeneration and repair

inferredcites →https://doi.org/10.1016/j.biomaterials.2017.03.029openalex-snapshot

Injectable nanofibrous spongy microspheres for NR4A1 plasmid DNA transfection to reverse fibrotic degeneration and support disc regeneration

inferredcites →https://doi.org/10.1016/j.biomaterials.2017.05.017openalex-snapshot

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inferredcites →https://doi.org/10.1016/j.jbiomech.2009.12.001openalex-snapshot

Mechanical design criteria for intervertebral disc tissue engineering

inferredcites →https://doi.org/10.1016/j.joca.2012.05.011openalex-snapshot

Association between spinal morning stiffness and lumbar disc degeneration: the Rotterdam Study

inferredcites →https://doi.org/10.1016/j.joca.2012.06.001openalex-snapshot

Tissue engineering approaches to degenerative disc disease – A meta-analysis of controlled animal trials

inferredcites →https://doi.org/10.1016/j.joca.2013.10.019openalex-snapshot

Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort: the Wakayama Spine Study

inferredcites →https://doi.org/10.1016/j.joca.2015.03.028openalex-snapshot

Mechanics and biology in intervertebral disc degeneration: a vicious circle

inferredcites →https://doi.org/10.1016/j.joca.2015.09.019openalex-snapshot

Aging and age related stresses: a senescence mechanism of intervertebral disc degeneration

inferredcites →https://doi.org/10.1016/j.micron.2007.08.009openalex-snapshot

Investigation of nano-mechanical properties of annulus fibrosus using atomic force microscopy

inferredcites →https://doi.org/10.1016/j.msec.2010.04.018openalex-snapshot

Culture of nucleus pulposus cells from intervertebral disc on self-assembling KLD-12 peptide hydrogel scaffold

inferredcites →https://doi.org/10.1016/j.semcancer.2007.10.001openalex-snapshot

Cell–matrix adhesion complexes: Master control machinery of cell migration

inferredcites →https://doi.org/10.1016/j.spinee.2004.07.010openalex-snapshot

Molecular basis of intervertebral disc degeneration

inferredcites →https://doi.org/10.1016/j.spinee.2012.12.002openalex-snapshot

Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its repair?

inferredcites →https://doi.org/10.1016/j.tibtech.2014.05.006openalex-snapshot

Intervertebral disc regeneration: a great challenge for tissue engineers

inferredcites →https://doi.org/10.1016/s0002-9440(10)63109-4openalex-snapshot

Mechanical Overload Induces VEGF in Cartilage Discs via Hypoxia-Inducible Factor

inferredcites →https://doi.org/10.1016/s0006-3495(99)77476-xopenalex-snapshot

Polymer-in-a-Box Mechanism for the Thermal Stabilization of Collagen Molecules in Fibers

inferredcites →https://doi.org/10.1016/s0021-9290(97)00069-9openalex-snapshot

The viscoelastic behavior of the non-degenerate human lumbar nucleus pulposus in shear

inferredcites →https://doi.org/10.1016/s0140-6736(12)61729-2openalex-snapshot

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

inferredcites →https://doi.org/10.1016/s0934-8832(11)80014-4openalex-snapshot

Cells Transmit Spatial Information by Orienting Collagen Fibers

inferredcites →https://doi.org/10.1016/s0945-053x(99)00039-6openalex-snapshot

Regulation of extracellular matrix gene expression by mechanical stress

inferredcites →https://doi.org/10.1038/ncomms12503openalex-snapshot

Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs

inferredcites →https://doi.org/10.1038/nrm2593openalex-snapshot

Environmental sensing through focal adhesions

inferredcites →https://doi.org/10.1038/nrrheum.2013.160openalex-snapshot

Role of cytokines in intervertebral disc degeneration: pain and disc content

inferredcites →https://doi.org/10.1038/nrrheum.2014.91openalex-snapshot

Intervertebral disc regeneration: do nutrients lead the way?

inferredcites →https://doi.org/10.1038/nrrheum.2015.13openalex-snapshot

Stem cell therapy for intervertebral disc regeneration: obstacles and solutions

inferredcites →https://doi.org/10.1039/b716663jopenalex-snapshot

Cellulose fibrils direct plant organ movements

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Types I and II collagens in intervertebral disc. Interchanging radial distributions in annulus fibrosus

inferredcites →https://doi.org/10.1042/bst0300864openalex-snapshot

Disc morphology in health and disease

inferredcites →https://doi.org/10.1046/j.1469-7580.2003.00162.xopenalex-snapshot

The three‐dimensional architecture of the notochordal nucleus pulposus: novel observations on cell structures in the canine intervertebral disc

inferredcites →https://doi.org/10.1073/pnas.1107094108openalex-snapshot

Tissue-engineered intervertebral discs produce new matrix, maintain disc height, and restore biomechanical function to the rodent spine

inferredcites →https://doi.org/10.1074/jbc.m607581200openalex-snapshot

Actin Filaments Are Required for Fibripositor-mediated Collagen Fibril Alignment in Tendon

inferredcites →https://doi.org/10.1080/03008200802714925openalex-snapshot

Expression of Laminin Isoforms, Receptors, and Binding Proteins Unique to Nucleus Pulposus Cells of Immature Intervertebral Disc

inferredcites →https://doi.org/10.1080/10520290802539186openalex-snapshot

Connective tissue growth factor expression in human intervertebral disc: implications for angiogenesis in intervertebral disc degeneration

inferredcites →https://doi.org/10.1083/jcb.200312071openalex-snapshot

Coalignment of plasma membrane channels and protrusions (fibripositors) specifies the parallelism of tendon

inferredcites →https://doi.org/10.1089/107632703768247368openalex-snapshot

The Notochordal Cell in the Nucleus Pulposus: A Review in the Context of Tissue Engineering

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Anatomy of Intervertebral Disc and Pathophysiology of Herniated Disc Disease

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Stem Cell Approaches to Intervertebral Disc Regeneration: Obstacles from the Disc Microenvironment

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Tissue-Engineering Approach to Regenerating the Intervertebral Disc

inferredcites →https://doi.org/10.1089/ten.tea.2008.0215openalex-snapshot

Intervertebral Disc Tissue Engineering Using a Novel Hyaluronic Acid–Nanofibrous Scaffold (HANFS) Amalgam

inferredcites →https://doi.org/10.1089/ten.tea.2009.0250openalex-snapshot

A Phenotypic Comparison of Proteoglycan Production of Intervertebral Disc Cells Isolated from Rats, Rabbits, and Bovine Tails; Which Animal Model is Most Suitable to Study Tissue Engineering and Biological Repair of Human Disc Disorders?

inferredcites →https://doi.org/10.1089/ten.tea.2009.0770openalex-snapshot

Experimental Intervertebral Disc Regeneration with Tissue-Engineered Composite in a Canine Model

inferredcites →https://doi.org/10.1089/ten.tea.2011.0632openalex-snapshot

Angiogenic Potential of Gellan-Gum-Based Hydrogels for Application in Nucleus Pulposus Regeneration: In Vivo Study

inferredcites →https://doi.org/10.1089/ten.tea.2013.0279openalex-snapshot

Biological Evaluation of Human Degenerated Nucleus Pulposus Cells in Functionalized Self-Assembling Peptide Nanofiber Hydrogel Scaffold

inferredcites →https://doi.org/10.1089/ten.tec.2011.0070openalex-snapshot

An In Vitro Model System to Quantify Stress Generation, Compaction, and Retraction in Engineered Heart Valve Tissue

inferredcites →https://doi.org/10.1093/rheumatology/16.1.22openalex-snapshot

BIOCHEMICAL ASPECTS OF DEVELOPMENT AND AGEING OF HUMAN LUMBAR INTERVERTEBRAL DISCS

inferredcites →https://doi.org/10.1097/00007632-198101000-00020openalex-snapshot

Disc Pressure Measurements

inferredcites →https://doi.org/10.1097/00007632-198401000-00011openalex-snapshot

The Torsional Injury of the Lumbar Spine

inferredcites →https://doi.org/10.1097/00007632-198902000-00005openalex-snapshot

Biochemical and Structural Properties of the Cartilage End-Plate and its Relation to the Intervertebral Disc

inferredcites →https://doi.org/10.1097/00007632-200002150-00016openalex-snapshot

Low Back Pain in Relation to Lumbar Disc Degeneration

inferredcites →https://doi.org/10.1097/00007632-200011010-00004openalex-snapshot

Observations on Fiber-Forming Collagens in the Anulus Fibrosus

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Preclinical Evaluation of a Poly (Vinyl Alcohol) Hydrogel Implant as a Replacement for the Nucleus Pulposus

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Tissue-Engineered Composites of Anulus Fibrosus and Nucleus Pulposus for Intervertebral Disc Replacement

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The Elastic Fiber Network of the Anulus Fibrosus of the Normal and Scoliotic Human Intervertebral Disc

inferredcites →https://doi.org/10.1097/01.brs.0000192236.92867.15openalex-snapshot

Effects of Degeneration on the Biphasic Material Properties of Human Nucleus Pulposus in Confined Compression

inferredcites →https://doi.org/10.1097/01.brs.0000244615.43199.07openalex-snapshot

Microendoscopic Discectomy for Lumbar Disc Herniation

inferredcites →https://doi.org/10.1097/brs.0b013e31817bb92copenalex-snapshot

ISSLS Prize Winner: Microstructure and Mechanical Disruption of the Lumbar Disc Annulus

inferredcites →https://doi.org/10.1097/brs.0b013e31817e2ce3openalex-snapshot

Characterization of Intervertebral Disc Aging

inferredcites →https://doi.org/10.1097/brs.0b013e318194e20copenalex-snapshot

Mechanical Stimulation Alters Pleiotrophin and Aggrecan Expression by Human Intervertebral Disc Cells and Influences Their Capacity to Stimulate Endothelial Cell Migration

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Prevalence and Pattern of Lumbar Magnetic Resonance Imaging Changes in a Population Study of One Thousand Forty-Three Individuals

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The Association Between Lumbar Disc Degeneration and Low Back Pain

inferredcites →https://doi.org/10.1097/brs.0b013e3181b26ed1openalex-snapshot

Differentiation of Intervertebral Notochordal Cells Through Live Automated Cell Imaging System In Vitro

inferredcites →https://doi.org/10.1097/brs.0b013e3181e70488openalex-snapshot

The Trend in Total Cost of Back Pain in the Netherlands in the Period 2002 to 2007

inferredcites →https://doi.org/10.1097/brs.0b013e31820566b2openalex-snapshot

Biological and Biomechanical Effects of Fibrin Injection Into Porcine Intervertebral Discs

inferredcites →https://doi.org/10.1097/brs.0b013e31820ea9a2openalex-snapshot

Early Failure of Metal-on-Metal Artificial Disc Prostheses Associated with Lymphocytic Reaction

inferredcites →https://doi.org/10.1097/brs.0b013e3182608ac4openalex-snapshot

ISSLS Prize Winner

inferredcites →https://doi.org/10.1098/rsta.2009.0093openalex-snapshot

Mechanical strain enhances survivability of collagen micronetworks in the presence of collagenase: implications for load-bearing matrix growth and stability

inferredcites →https://doi.org/10.1111/j.0021-8782.2004.00306.xopenalex-snapshot

Integrin expression in cells of the intervertebral disc

inferredcites →https://doi.org/10.1111/j.0021-8782.2004.00352.xopenalex-snapshot

Cytomorphology of notochordal and chondrocytic cells from the nucleus pulposus: a species comparison

inferredcites →https://doi.org/10.1111/j.1432-0436.1988.tb00083.xopenalex-snapshot

Expression of cytokeratin and vimentin in nucleus pulposus cells

inferredcites →https://doi.org/10.1111/j.1469-7580.2006.00536.xopenalex-snapshot

The structural basis of interlamellar cohesion in the intervertebral disc wall

inferredcites →https://doi.org/10.1111/j.1469-7580.2007.00707.xopenalex-snapshot

Microfibrils, elastin fibres and collagen fibres in the human intervertebral disc and bovine tail disc

inferredcites →https://doi.org/10.1115/1.2796072openalex-snapshot

An Anisotropic Biphasic Theory of Tissue-Equivalent Mechanics: The Interplay Among Cell Traction, Fibrillar Network Deformation, Fibril Alignment, and Cell Contact Guidance

inferredcites →https://doi.org/10.1115/1.4026360openalex-snapshot

The Role Of Extracellular Matrix Elasticity and Composition In Regulating the Nucleus Pulposus Cell Phenotype in the Intervertebral Disc: A Narrative Review

inferredcites →https://doi.org/10.1126/science.1214804openalex-snapshot

Designing Cell-Compatible Hydrogels for Biomedical Applications

inferredcites →https://doi.org/10.1139/o95-043openalex-snapshot

Mechanoreception at the cellular level: the detection, interpretation, and diversity of responses to mechanical signals

inferredcites →https://doi.org/10.1152/ajpcell.1997.272.5.c1499openalex-snapshot

Proteoglycan synthesis in the intervertebral disk nucleus: the role of extracellular osmolality

inferredcites →https://doi.org/10.1159/000356667openalex-snapshot

Calcium's Role in Mechanotransduction during Muscle Development

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Actin and Type I Collagen Propeptide Distribution in the Developing Chick Cornea

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Matrix Metalloproteinases: A Review

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Notochordal cells protect nucleus pulposus cells from degradation and apoptosis: implications for the mechanisms of intervertebral disc degeneration

inferredcites →https://doi.org/10.1186/ar4460openalex-snapshot

Notochordal cell disappearance and modes of apoptotic cell death in a rat tail static compression-induced disc degeneration model

inferredcites →https://doi.org/10.1186/ar629openalex-snapshot

Degeneration of the intervertebral disc.

inferredcites →https://doi.org/10.1242/jcs.109.4.713openalex-snapshot

Mechanism of endothelial cell shape change and cytoskeletal remodeling in response to fluid shear stress

inferredcites →https://doi.org/10.1302/0301-620x.52b2.371openalex-snapshot

SULPHATED ACID MUCOPOLYSACCHARIDE METABOLISM IN THE RABBIT INTERVERTEBRAL DISC

inferredcites →https://doi.org/10.1302/0301-620x.65b2.6826631openalex-snapshot

The effect of fatigue on the lumbar intervertebral disc

inferredcites →https://doi.org/10.1371/journal.pone.0012337openalex-snapshot

Mechanical Strain Stabilizes Reconstituted Collagen Fibrils against Enzymatic Degradation by Mammalian Collagenase Matrix Metalloproteinase 8 (MMP-8)

inferredcites →https://doi.org/10.1371/journal.pone.0086723openalex-snapshot

Comparison of Decellularization Protocols for Preparing a Decellularized Porcine Annulus Fibrosus Scaffold

inferredcites →https://doi.org/10.1371/journal.pone.0131827openalex-snapshot

A Structurally and Functionally Biomimetic Biphasic Scaffold for Intervertebral Disc Tissue Engineering

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Transforming growth factor-β1 increases lysyl oxidase expression by downregulating MIR29A in human granulosa lutein cells

inferredcites →https://doi.org/10.1679/aohc1950.36.39openalex-snapshot

Three-Dimensional Observation of Collagen Framework of Intervertebral Discs in Rats, Dogs and Humans

inferredcites →https://doi.org/10.18632/oncotarget.14389openalex-snapshot

Epoxyeicosanoids prevent intervertebral disc degenerationin vitroandin vivo

inferredcites →https://doi.org/10.2106/00004623-200604002-00009openalex-snapshot

EFFECTS OF MECHANICAL LOADING ON INTERVERTEBRAL DISC METABOLISM IN VIVO

inferredcites →https://doi.org/10.2106/00004623-200604002-00011openalex-snapshot

MECHANOBIOLOGY OF THE INTERVERTEBRAL DISC AND RELEVANCE TO DISC DEGENERATION

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Suppression of adverse angiogenesis in an albumin-based hydrogel for articular cartilage and intervertebral disc regeneration

inferredcites →https://doi.org/10.4161/bioa.25503openalex-snapshot

The vacuole within

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4620814openalex-extracted

Improved Repair Effect of Crosslinking Stabilization Strategy for Annulus Fibrosus (Af) Defect

inferred← citeshttps://doi.org/10.1002/adhm.202201824openalex-snapshot

Collagen Niches Affect Direct Transcriptional Conversion toward Human Nucleus Pulposus Cells via Actomyosin Contractility

inferred← citeshttps://doi.org/10.1002/adhm.202501662openalex-snapshot

Injectable ROS‐Scavenging Trimetallic Nanocomposite Hydrogel Modulates Oxidative Microenvironment for Treatment of Intervertebral Disc Degeneration

inferred← citeshttps://doi.org/10.1002/advs.202404496openalex-snapshot

Preserving the Immune‐Privileged Niche of the Nucleus Pulposus: Safeguarding Intervertebral Discs from Degeneration after Discectomy with Synthetic Mucin Hydrogel Injection

inferred← citeshttps://doi.org/10.1002/jbm.b.34323openalex-snapshot

The establishment and biological assessment of a whole tissue‐engineered intervertebral disc with PBST fibers and a chitosan hydrogel in vitro and in vivo

inferred← citeshttps://doi.org/10.1002/jor.25136openalex-snapshot

Correlational analysis of chemokine and inflammatory cytokine expression in the intervertebral disc and blood in patients with lumbar disc disease

inferred← citeshttps://doi.org/10.1007/978-3-032-05466-1_12openalex-snapshot

Lumbar Prosthesis Assessment in Swine Vertebrae Under Torsional Payload

inferred← citeshttps://doi.org/10.1007/978-981-99-9404-5_17openalex-snapshot

Lumbar Disc Disease: An Overview

inferred← citeshttps://doi.org/10.1007/s00586-025-08833-wopenalex-snapshot

Predictive factors associated with the onset of Kummell’s disease

inferred← citeshttps://doi.org/10.1007/s00586-025-08843-8openalex-snapshot

Ultrasound guidance for intervertebral disc location and paravertebral tissue swelling quantification in a mouse model of intervertebral disc herniation

inferred← citeshttps://doi.org/10.1007/s11916-023-01188-1openalex-snapshot

Roles of Chemokines in Intervertebral Disk Degeneration

inferred← citeshttps://doi.org/10.1007/s13273-022-00254-wopenalex-snapshot

Amphiregulin secreted by cartilage endplate stem cells inhibits intervertebral disk degeneration and TNF-α production via PI3K/AKT and ERK1/2 signaling pathways

inferred← citeshttps://doi.org/10.1007/s40846-026-01033-xopenalex-snapshot

High-Precision Design and Additive Manufacturing of Patient-Specific L5-S1 Annulus Fibrosus Scaffolds: A CFD-Optimized and Biomechanical Approach

inferred← citeshttps://doi.org/10.1016/j.bioactmat.2024.07.031openalex-snapshot

An anti-senescence hydrogel with pH-responsive drug release for mitigating intervertebral disc degeneration and low back pain

inferred← citeshttps://doi.org/10.1016/j.bioactmat.2024.10.012openalex-snapshot

The anti-oxidation related bioactive materials for intervertebral disc degeneration regeneration and repair

inferred← citeshttps://doi.org/10.1016/j.biomaterials.2024.122509openalex-snapshot

Injectable pathological microenvironment-responsive anti-inflammatory hydrogels for ameliorating intervertebral disc degeneration

inferred← citeshttps://doi.org/10.1016/j.cej.2025.171710openalex-snapshot

Injectable piezoelectric nanomicelle hydrogels encapsulating α-tocopherol for the treatment of intervertebral disc degeneration by regulating the metabolic homeostasis of nucleus pulposus cells

inferred← citeshttps://doi.org/10.1016/j.eurpolymj.2022.111681openalex-snapshot

A perspective on the wet spinning process and its advancements in biomedical sciences

inferred← citeshttps://doi.org/10.1016/j.exger.2025.112872openalex-snapshot

From strength to strain: How sarcopenia contributes to chronic low back pain

inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112444openalex-snapshot

Hyperforin improves matrix stiffness induced nucleus pulposus inflammatory degeneration by activating mitochondrial fission

inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112717openalex-snapshot

Isorhapontigenin delays senescence and matrix degradation of nucleus pulposus cells via PI3K/AKT/mTOR-mediated autophagy pathway in vitro and alleviates intervertebral disc degeneration in vivo

inferred← citeshttps://doi.org/10.1016/j.jconrel.2025.114066openalex-snapshot

Hydrogel delivery systems in intervertebral disc degeneration: Current status and future perspectives

inferred← citeshttps://doi.org/10.1016/j.mtbio.2025.101625openalex-snapshot

Crosslinking stabilization strategy: A novel approach to cartilage-like repair of annulus fibrosus (AF) defects

inferred← citeshttps://doi.org/10.1016/j.mtbio.2025.102630openalex-snapshot

ROS/pH dynamically responsive injectable hydrogel ameliorates disc degeneration by re-establishing the oxidative stress microenvironment

inferred← citeshttps://doi.org/10.1016/j.phrs.2025.107887openalex-snapshot

Primary cilia as mechanosensors in musculoskeletal homeostasis and disease

inferred← citeshttps://doi.org/10.1016/j.spinee.2025.01.036openalex-snapshot

Risk factors for progression of nucleus pulposus degeneration in the lumbar intervertebral disc: a retrospective analysis using the disc signal intensity index

inferred← citeshttps://doi.org/10.1016/j.wneu.2020.11.005openalex-snapshot

Does Osteoporosis Affect the Adjacent Segments Following Anterior Lumbar Interbody Fusion? A Finite Element Study

inferred← citeshttps://doi.org/10.1016/j.ymthe.2022.05.021openalex-snapshot

Self-amplifying loop of NF-κB and periostin initiated by PIEZO1 accelerates mechano-induced senescence of nucleus pulposus cells and intervertebral disc degeneration

inferred← citeshttps://doi.org/10.1021/acsbiomaterials.1c00970openalex-snapshot

Recent Progress in Electrospun Nanofiber-Based Degenerated Intervertebral Disc Repair

inferred← citeshttps://doi.org/10.1021/acsbiomaterials.3c01091openalex-snapshot

Mechanical Factors Regulate Annulus Fibrosus (AF) Injury Repair and Remodeling: A Review

inferred← citeshttps://doi.org/10.1080/10255842.2025.2566253openalex-snapshot

Comparison of lumbar fusion and artificial disc replacement: a finite element analysis

inferred← citeshttps://doi.org/10.1101/2021.11.23.469730openalex-snapshot

Identification of biological processes and signaling pathways in the stretched nucleus pulposus cells

inferred← citeshttps://doi.org/10.1155/2022/3860898openalex-snapshot

Effects of Fluid Shear Stress on Human Intervertebral Disc Nucleus Pulposus Cells Based on Label-Free Quantitative Proteomics

inferred← citeshttps://doi.org/10.1177/08853282231173115openalex-snapshot

Development and Characterization of a AuNP-Genipin-Viscoelastic Collagen Material

inferred← citeshttps://doi.org/10.12336/biomatertransl.2021.04.001openalex-snapshot

Cellular modulation by the mechanical cues from biomaterials for tissue engineering.

inferred← citeshttps://doi.org/10.12659/msm.924236openalex-snapshot

Structure Design and Optimization of the C5–C6 Cervical Intervertebral Fusion Cage Using the Anterior Cervical Plate and Cage Fixation System

inferred← citeshttps://doi.org/10.1590/1806-9282.66.7.986openalex-snapshot

Nuclear factor erythroid-2 related factor 2 inhibits human disc nucleus pulpous cells apoptosis induced by excessive hydrogen peroxide

inferred← citeshttps://doi.org/10.17650/1818-8338-2020-14-1-2-42-54openalex-snapshot

Cellular and molecular aspects of degenerative disc disease and potential strategies of biological therapy

inferred← citeshttps://doi.org/10.21203/rs.3.rs-4356277/v1openalex-snapshot

HIF-1α/Bnip3/VEGF axis regulates autophagy to mitigate intervertebral disc degeneration induced by inflammatory factor TNF-α

inferred← citeshttps://doi.org/10.24060/2076-3093-2020-10-2-108-114openalex-snapshot

Non-Coding RNA Extraction from Nucleus Pulposus of Intervertebral Discs with Subsequent Expression Profiling

inferred← citeshttps://doi.org/10.3389/fbioe.2020.00262openalex-snapshot

Extracellular Matrix From Decellularized Wharton’s Jelly Improves the Behavior of Cells From Degenerated Intervertebral Disc

inferred← citeshttps://doi.org/10.3389/fimmu.2023.1136727openalex-snapshot

Identification of a potential novel biomarker in intervertebral disk degeneration by bioinformatics analysis and experimental validation

inferred← citeshttps://doi.org/10.3389/fimmu.2023.1188774openalex-snapshot

MAPK8 and CAPN1 as potential biomarkers of intervertebral disc degeneration overlapping immune infiltration, autophagy, and ceRNA

inferred← citeshttps://doi.org/10.3389/fimmu.2024.1441028openalex-snapshot

Machine learning-based diagnostic model of lymphatics-associated genes for new therapeutic target analysis in intervertebral disc degeneration

inferred← citeshttps://doi.org/10.3389/fimmu.2026.1809762openalex-snapshot

Deciphering the regulatory mechanism and therapeutic potential of ECM degradation in intervertebral disc degeneration via multi-omics integration

inferred← citeshttps://doi.org/10.3390/app11041919openalex-snapshot

Advances in Tissue Engineering for Disc Repair

inferred← citeshttps://doi.org/10.3390/polym13111852openalex-snapshot

Collagen–Alginate Composite Hydrogel: Application in Tissue Engineering and Biomedical Sciences

inferred← citeshttps://doi.org/10.4067/s0717-95022022000300824openalex-snapshot

Study of Nonlinear Viscoelastic Mechanical Properties of Degenerated Intervertebral Discs

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.