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Perfluoroalkyl Acid Binding with Peroxisome Proliferator-Activated Receptors α, γ, and δ, and Fatty Acid Binding Proteins by Equilibrium Dialysis with a Comparison of Methods

https://doi.org/10.3390/toxics9030045
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Perfluorooctanoic Acid, Perfluorooctanesulfonate, and Serum Lipids in Children and Adolescents
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Analyzing Binding Data
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Fundamentals of Analytical Toxicology
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Surface characterization of human serum albumin and sodium perfluorooctanoate mixed solutions by pendant drop tensiometry and circular dichroism
inferredcites →https://doi.org/10.1002/etc.199openalex-snapshot
Experimental characterization of the mechanism of perfluorocarboxylic acids' liver protein bioaccumulation: The key role of the neutral species
inferredcites →https://doi.org/10.1002/etc.647openalex-snapshot
Strong associations of short-chain perfluoroalkyl acids with serum albumin and investigation of binding mechanisms
inferredcites →https://doi.org/10.1002/ieam.258openalex-snapshot
Perfluoroalkyl and polyfluoroalkyl substances in the environment: Terminology, classification, and origins
inferredcites →https://doi.org/10.1007/b137833openalex-snapshot
Practical Methods in Cardiovascular Research
inferredcites →https://doi.org/10.1007/s00204-014-1391-7openalex-snapshot
Interaction of perfluoroalkyl acids with human liver fatty acid-binding protein
inferredcites →https://doi.org/10.1007/s00204-017-2055-1openalex-snapshot
Cytotoxicity of novel fluorinated alternatives to long-chain perfluoroalkyl substances to human liver cell line and their binding capacity to human liver fatty acid binding protein
inferredcites →https://doi.org/10.1016/j.chemosphere.2010.11.003openalex-snapshot
6:2 Fluorotelomer sulfonate aerobic biotransformation in activated sludge of waste water treatment plants
inferredcites →https://doi.org/10.1016/j.chemosphere.2018.01.152openalex-snapshot
Interactions of perfluorooctanoic acid and perfluorooctanesulfonic acid with serum albumins by native mass spectrometry, fluorescence and molecular docking
inferredcites →https://doi.org/10.1016/j.ecoenv.2003.09.012openalex-snapshot
Effects of perfluorooctane sulfonate and perfluorooctanoic acid on the zooplanktonic community
inferredcites →https://doi.org/10.1016/j.ecoenv.2013.06.006openalex-snapshot
Profiles of perfluoroalkyl substances in the liver and serum of patients with liver cancer and cirrhosis in Australia
inferredcites →https://doi.org/10.1016/j.envint.2007.02.015openalex-snapshot
Identification and pattern of perfluorooctane sulfonate (PFOS) isomers in human serum and plasma
inferredcites →https://doi.org/10.1016/j.envint.2017.06.007openalex-snapshot
Per- and polyfluoroalkyl substances in human serum and urine samples from a residentially exposed community
inferredcites →https://doi.org/10.1016/j.envpol.2010.01.023openalex-snapshot
Perfluorinated compounds in water, sediment, soil and biota from estuarine and coastal areas of Korea
inferredcites →https://doi.org/10.1016/j.envpol.2010.09.008openalex-snapshot
Distribution of perfluorochemicals between sera and milk from the same mothers and implications for prenatal and postnatal exposures
inferredcites →https://doi.org/10.1016/j.envres.2014.06.012openalex-snapshot
Associations between Perfluoroalkyl acids (PFASs) and maternal thyroid hormones in early pregnancy: A population-based cohort study
inferredcites →https://doi.org/10.1016/j.ijheh.2011.08.016openalex-snapshot
Perfluorinated compounds in the vicinity of a fire training area – Human biomonitoring among 10 persons drinking water from contaminated private wells in Cologne, Germany
inferredcites →https://doi.org/10.1016/j.ijheh.2012.08.004openalex-snapshot
Retrospective monitoring of perfluorocarboxylates and perfluorosulfonates in human plasma archived by the German Environmental Specimen Bank
inferredcites →https://doi.org/10.1016/j.ijheh.2016.12.014openalex-snapshot
ADONA and perfluoroalkylated substances in plasma samples of German blood donors living in South Germany
inferredcites →https://doi.org/10.1016/j.jsb.2015.07.006openalex-snapshot
Different binding and recognition modes of GL479, a dual agonist of Peroxisome Proliferator-Activated Receptor α/γ
inferredcites →https://doi.org/10.1016/j.sbi.2010.10.002openalex-snapshot
Protein binding specificity versus promiscuity
inferredcites →https://doi.org/10.1016/j.scitotenv.2018.09.214openalex-snapshot
Isomer-specific biotransformation of perfluoroalkyl sulfonamide compounds in aerobic soil
inferredcites →https://doi.org/10.1016/j.taap.2014.06.020openalex-snapshot
Structure-dependent binding and activation of perfluorinated compounds on human peroxisome proliferator-activated receptor γ
inferredcites →https://doi.org/10.1016/j.tiv.2019.104700openalex-snapshot
Activation of human nuclear receptors by perfluoroalkylated substances (PFAS)
inferredcites →https://doi.org/10.1016/j.tox.2003.11.005openalex-snapshot
The reproductive toxicology of ammonium perfluorooctanoate (APFO) in the rat
inferredcites →https://doi.org/10.1016/j.tox.2011.12.014openalex-snapshot
Hepatocellular hypertrophy and cell proliferation in Sprague–Dawley rats from dietary exposure to potassium perfluorooctanesulfonate results from increased expression of xenosensor nuclear receptors PPARα and CAR/PXR
inferredcites →https://doi.org/10.1016/s0300-483x(02)00081-1openalex-snapshot
Interactions of flurochemicals with rat liver fatty acid-binding protein
inferredcites →https://doi.org/10.1021/ac902238uopenalex-snapshot
Binding of Perfluorocarboxylates to Serum Albumin: A Comparison of Analytical Methods
inferredcites →https://doi.org/10.1021/acs.est.5b01040openalex-snapshot
Physical and Biological Release of Poly- and Perfluoroalkyl Substances (PFASs) from Municipal Solid Waste in Anaerobic Model Landfill Reactors
inferredcites →https://doi.org/10.1021/acs.est.5b04773openalex-snapshot
Effects of Aqueous Film-Forming Foams (AFFFs) on Trichloroethene (TCE) Dechlorination by a Dehalococcoides mccartyi-Containing Microbial Community
inferredcites →https://doi.org/10.1021/acs.est.8b01268openalex-snapshot
Predicting Relative Protein Affinity of Novel Per- and Polyfluoroalkyl Substances (PFASs) by An Efficient Molecular Dynamics Approach
inferredcites →https://doi.org/10.1021/acs.est.8b07273openalex-snapshot
In Vitro and In Silico Evaluations of Binding Affinities of Perfluoroalkyl Substances to Baikal Seal and Human Peroxisome Proliferator-Activated Receptor α
inferredcites →https://doi.org/10.1021/es050989vopenalex-snapshot
Avian Toxicity Reference Values for Perfluorooctane Sulfonate
inferredcites →https://doi.org/10.1021/es0512475openalex-snapshot
Sources, Fate and Transport of Perfluorocarboxylates
inferredcites →https://doi.org/10.1021/es0517973openalex-snapshot
Perfluorochemicals in Pooled Serum Samples from United States Residents in 2001 and 2002
inferredcites →https://doi.org/10.1021/es060031fopenalex-snapshot
Health Risks in Infants Associated with Exposure to Perfluorinated Compounds in Human Breast Milk from Zhoushan, China
inferredcites →https://doi.org/10.1021/es070895gopenalex-snapshot
Are PFCAs Bioaccumulative? A Critical Review and Comparison with Regulatory Criteria and Persistent Lipophilic Compounds
inferredcites →https://doi.org/10.1021/es101334sopenalex-snapshot
Noncovalent Interactions of Long-Chain Perfluoroalkyl Acids with Serum Albumin
inferredcites →https://doi.org/10.1021/es104326wopenalex-snapshot
Monitoring of Perfluorinated Compounds in Aquatic Biota: An Updated Review
inferredcites →https://doi.org/10.1021/es301465nopenalex-snapshot
Identification of Novel Fluorochemicals in Aqueous Film-Forming Foams Used by the US Military
inferredcites →https://doi.org/10.1021/es3034999openalex-snapshot
Zwitterionic, Cationic, and Anionic Fluorinated Chemicals in Aqueous Film Forming Foam Formulations and Groundwater from U.S. Military Bases by Nonaqueous Large-Volume Injection HPLC-MS/MS
inferredcites →https://doi.org/10.1021/es303627kopenalex-snapshot
Correction to Identification of Novel Fluorochemicals in Aqueous Film-Forming Foams Used by the US Military
inferredcites →https://doi.org/10.1021/es303716kopenalex-snapshot
Part I. A Temporal Study of PFCAs and Their Precursors in Human Plasma from Two German Cities 1982–2009
inferredcites →https://doi.org/10.1021/es3048043openalex-snapshot
Subsurface Transport Potential of Perfluoroalkyl Acids at Aqueous Film-Forming Foam (AFFF)-Impacted Sites
inferredcites →https://doi.org/10.1021/es4004153openalex-snapshot
Part II. A Temporal Study of PFOS and Its Precursors in Human Plasma from Two German Cities in 1982–2009
inferredcites →https://doi.org/10.1021/es4018877openalex-snapshot
Persistence of Perfluoroalkyl Acid Precursors in AFFF-Impacted Groundwater and Soil
inferredcites →https://doi.org/10.1021/es4026722openalex-snapshot
Structure-Based Investigation on the Interaction of Perfluorinated Compounds with Human Liver Fatty Acid Binding Protein
inferredcites →https://doi.org/10.1021/es404008gopenalex-snapshot
Bioaccumulation of Perfluorinated Alkyl Acids: Observations and Models
inferredcites →https://doi.org/10.1021/es505399wopenalex-snapshot
Isomer-Specific Binding Affinity of Perfluorooctanesulfonate (PFOS) and Perfluorooctanoate (PFOA) to Serum Proteins
inferredcites →https://doi.org/10.1021/es800695mopenalex-snapshot
Serum Concentrations of Polyfluoroalkyl Compounds in Faroese Whale Meat Consumers
inferredcites →https://doi.org/10.1021/jp051655vopenalex-snapshot
Conformational Changes in Human Serum Albumin Induced by Sodium Perfluorooctanoate in Aqueous Solutions
inferredcites →https://doi.org/10.1021/tx034005wopenalex-snapshot
Binding of Perfluorooctanoic Acid to Rat and Human Plasma Proteins
inferredcites →https://doi.org/10.1038/nrd2589openalex-snapshot
Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets
inferredcites →https://doi.org/10.1039/c9em00218aopenalex-snapshot
Investigation of binding and activity of perfluoroalkyl substances to the human peroxisome proliferator-activated receptor β/δ
inferredcites →https://doi.org/10.1071/en10145openalex-snapshot
Environmental levels and distribution of structural isomers of perfluoroalkyl acids after aqueous fire-fighting foam (AFFF) contamination
inferredcites →https://doi.org/10.1071/en13128openalex-snapshot
Organic fluorine content in aqueous film forming foams (AFFFs) and biodegradation of the foam component 6 : 2 fluorotelomermercaptoalkylamido sulfonate (6 : 2 FTSAS)
inferredcites →https://doi.org/10.1074/jbc.m111.270165openalex-snapshot
Fatty Acid Induced Remodeling within the Human Liver Fatty Acid-binding Protein
inferredcites →https://doi.org/10.1074/jbc.m111.294785openalex-snapshot
Identification and Mechanism of 10-Carbon Fatty Acid as Modulating Ligand of Peroxisome Proliferator-activated Receptors
inferredcites →https://doi.org/10.1074/jbc.m609491200openalex-snapshot
In Vitro Comparative Kinetic Analysis of the Chloroplast Toc GTPases
inferredcites →https://doi.org/10.1080/01932690903294139openalex-snapshot
Study on the Interaction Between Bovine Serum Albumin and Potassium Perfluoro Octane Sulfonate
inferredcites →https://doi.org/10.1088/2050-6120/4/2/022001openalex-snapshot
Fluorescence polarization assays in high-throughput screening and drug discovery: a review
inferredcites →https://doi.org/10.1089/15209150260007381openalex-snapshot
Physiological and Therapeutic Roles of Peroxisome Proliferator-Activated Receptors
inferredcites →https://doi.org/10.1091/mbc.e10-08-0683openalex-snapshot
A Guide to Simple and Informative Binding Assays
inferredcites →https://doi.org/10.1093/aje/kwp279openalex-snapshot
Association of Perfluorooctanoic Acid and Perfluorooctane Sulfonate With Serum Lipids Among Adults Living Near a Chemical Plant
inferredcites →https://doi.org/10.1093/toxsci/kfm128openalex-snapshot
Perfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings
inferredcites →https://doi.org/10.1107/s1744309110051481openalex-snapshot
Preparation, crystallization and preliminary X-ray diffraction analysis of two intestinal fatty-acid binding proteins in the presence of 11-(dansylamino)undecanoic acid
inferredcites →https://doi.org/10.1128/mcb.15.6.3012openalex-snapshot
Targeted Disruption of the α Isoform of the Peroxisome Proliferator-Activated Receptor Gene in Mice Results in Abolishment of the Pleiotropic Effects of Peroxisome Proliferators
inferredcites →https://doi.org/10.1146/annurev.cellbio.12.1.335openalex-snapshot
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS: A Nuclear Receptor Signaling Pathway in Lipid Physiology
inferredcites →https://doi.org/10.1186/1472-6807-9-31openalex-snapshot
Interaction of perfluorooctanoic acid with human serum albumin
inferredcites →https://doi.org/10.1186/1758-2946-4-17openalex-snapshot
Avogadro: an advanced semantic chemical editor, visualization, and analysis platform
inferredcites →https://doi.org/10.1289/ehp.0800517openalex-snapshot
Do Perfluoroalkyl Compounds Impair Human Semen Quality?
inferredcites →https://doi.org/10.1289/ehp.1003328openalex-snapshot
Peroxisome Proliferator-Activated Receptor γ Is a Target for Halogenated Analogs of Bisphenol A
inferredcites →https://doi.org/10.1289/ehp.1206372openalex-snapshot
Serum Perfluorooctanoic Acid and Perfluorooctane Sulfonate Concentrations in Relation to Birth Outcomes in the Mid-Ohio Valley, 2005–2010
inferredcites →https://doi.org/10.1371/journal.pone.0033643openalex-snapshot
Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding
inferredcites →https://doi.org/10.1371/journal.pone.0072426openalex-snapshot
A Novel High Throughput Biochemical Assay to Evaluate the HuR Protein-RNA Complex Formation

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Per- and Polyfluorinated Alkyl Substances in an Urban Terrestrial Ecosystem and Trophic Magnification with a Food Chain Approach
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inferred← citeshttps://doi.org/10.1002/ieam.4579openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/978-3-031-07392-2_67openalex-snapshot
Per- and Polyfluoroalkyl Substances (PFAS) and Their Toxicology as Evidenced Through Disease and Biomarkers
inferred← citeshttps://doi.org/10.1007/s00204-026-04429-5openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/b978-0-323-88462-4.00018-3openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.cbi.2025.111793openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.chemosphere.2024.142253openalex-snapshot
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Perfluorooctanesulfonate Induces an Atypical Adipocyte Phenotype: Promoting Adipogenesis and Thermogenesis via PPARγ Signaling and m6A RNA Modifications in 3T3-L1 Cells
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Binding of Per- and Polyfluoroalkyl Substances (PFAS) to the PPARγ/RXRα–DNA Complex
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Broad PFAS Binding with Fatty Acid Binding Protein 4 Is Enabled by Variable Binding Modes
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Per- and polyfluoroalkyl substances alter innate immune function: evidence and data gaps
inferred← citeshttps://doi.org/10.1093/etojnl/vgag143openalex-snapshot
Histopathology and transcriptomics in male zebrafish livers from a perfluorooctanesulfonic acid multigenerational exposure inform adverse outcome pathway development for liver steatosis
inferred← citeshttps://doi.org/10.1093/etojnl/vgag246openalex-snapshot
What biology receives: Per- and polyfluoroalkyl substances, microplastics, and contact dose at living interfaces
inferred← citeshttps://doi.org/10.1093/toxsci/kfaf013openalex-snapshot
Distribution of perfluorooctanoic acid in exposed female postpubertal pigs in thermal neutral or heat-stressed conditions
inferred← citeshttps://doi.org/10.1097/ee9.0000000000000476openalex-snapshot
Prediction of endometrial tissue PFAS concentrations using serum levels, demographic, and reproductive factors: Findings from the Investigating Mixtures of Pollutants and Endometriosis in Tissue (IMPLANT) study
inferred← citeshttps://doi.org/10.1101/2025.10.27.684906openalex-snapshot
Structural and Biophysical Basis for PFAS Binding by Human Sterol Carrier Protein-2
inferred← citeshttps://doi.org/10.1186/s12940-022-00958-5openalex-snapshot
Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS)
inferred← citeshttps://doi.org/10.1186/s12940-024-01145-4openalex-snapshot
Integrated analysis of per- and polyfluoroalkyl substances and plasma lipidomics profiles in multi-ethnic Asian subjects for exposome research
inferred← citeshttps://doi.org/10.1210/endocr/bqab194openalex-snapshot
PFAS and Potential Adverse Effects on Bone and Adipose Tissue Through Interactions With PPARγ
inferred← citeshttps://doi.org/10.1360/ssc-2026-0134openalex-snapshot
Emerging technologies in environmental toxicology based on pollutant-protein interactions
inferred← citeshttps://doi.org/10.3389/fendo.2021.683297openalex-snapshot
Early-Life Exposure to Per- and Poly-Fluorinated Alkyl Substances and Growth, Adiposity, and Puberty in Children: A Systematic Review
inferred← citeshttps://doi.org/10.3389/fendo.2023.1302965openalex-snapshot
PFOS-elicited metabolic perturbation in liver and fatty acid metabolites in testis of adult mice
inferred← citeshttps://doi.org/10.3389/ftox.2026.1814052openalex-snapshot
Perfluorooctanoic acid (PFOA) induces lipid accumulation, oxidative stress, and reduced neurogenesis in primary human neuronal progenitor cells
inferred← citeshttps://doi.org/10.3390/ijms25158241openalex-snapshot
Large-Scale Screening of Per- and Polyfluoroalkyl Substance Binding Interactions and Their Mixtures with Nuclear Receptors
inferred← citeshttps://doi.org/10.3390/jox16020054openalex-snapshot
Toward Comprehensive In Vitro Evaluation of Serum Albumin Binding of Per- and Polyfluoroalkyl Substances
inferred← citeshttps://doi.org/10.3390/molecules31111880openalex-snapshot
Urine-to-Blood Partitioning of Per- and Polyfluoroalkyl Substances in Human Biomonitoring: Implications for Environmental Exposure Analysis and Bioaccumulation Assessment
inferred← citeshttps://doi.org/10.3390/physiologia4040035openalex-snapshot
Per- and Polyfluoroalkyl Substances (PFAS) as Emerging Obesogens: Mechanisms, Epidemiological Evidence, and Regulatory Challenges
inferred← citeshttps://doi.org/10.3390/toxics12100732openalex-snapshot
Effects of Perfluorinated Alkyl Substances (PFAS) on Amphibian Body and Liver Conditions: Is Lipid Metabolism Being Perturbed throughout Metamorphosis?
inferred← citeshttps://doi.org/10.3390/toxics13090732openalex-snapshot
Toxicological, Chemical, Social, and Economic Challenges Associated with PFAS and Replacement Aqueous Film-Forming Foams (AFFF)
inferred← citeshttps://doi.org/10.5281/zenodo.187792openalex-snapshot
FIGURE 3. Placospherastra antillensis n.g., n in New sciophilous sponges from the Caribbean (Porifera: Demospongiae)
inferred← citeshttps://doi.org/10.5937/arhfarm71-34197openalex-snapshot
Endocrine disruption by PFAS: A major concern associated with legacy and replacement substances
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