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Interim analysis of a 3-year follow-up study of NS5A and NS3 resistance-associated substitutions after treatment with grazoprevir-containing regimens in participants with chronic HCV infection

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/cmdc.201300343openalex-snapshot
Discovery of MK‐8742: An HCV NS5A Inhibitor with Broad Genotype Activity
inferredcites →https://doi.org/10.1002/hep.27934openalex-snapshot
Hepatitis C virus drug resistance–associated substitutions: State of the art summary
inferredcites →https://doi.org/10.1002/hep.27950openalex-snapshot
Hepatitis C guidance: AASLD‐IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus
inferredcites →https://doi.org/10.1002/hep.29139openalex-snapshot
Elbasvir/Grazoprevir for Patients With Hepatitis C Virus Infection and Inherited Blood Disorders: A Phase III Study
inferredcites →https://doi.org/10.1002/hep.29358openalex-snapshot
Grazoprevir, ruzasvir, and uprifosbuvir for hepatitis C virus after NS5A treatment failure
inferredcites →https://doi.org/10.1002/hep.29837openalex-snapshot
Resistance analysis of genotype 3 hepatitis C virus indicates subtypes inherently resistant to nonstructural protein 5A inhibitors
inferredcites →https://doi.org/10.1002/hep4.1050openalex-snapshot
Sequencing of hepatitis C virus for detection of resistance to direct‐acting antiviral therapy: A systematic review
inferredcites →https://doi.org/10.1002/jmv.25048openalex-snapshot
Prevalence of NS5A resistance associated substitutions in patients with hepatitis C virus genotypes 1a and 3: Impact on current therapeutic strategies
inferredcites →https://doi.org/10.1007/978-1-62703-484-5_12openalex-snapshot
Amplification and Sequencing of the Hepatitis C Virus NS3/4A Protease and the NS5B Polymerase Regions for Genotypic Resistance Detection of Clinical Isolates of Subtypes 1a and 1b
inferredcites →https://doi.org/10.1016/j.antiviral.2014.10.010openalex-snapshot
Long-term follow-up of patients receiving boceprevir for treatment of chronic hepatitis C
inferredcites →https://doi.org/10.1016/j.jhep.2015.04.009openalex-snapshot
Grazoprevir and elbasvir plus ribavirin for chronic HCV genotype-1 infection after failure of combination therapy containing a direct-acting antiviral agent
inferredcites →https://doi.org/10.1016/s0140-6736(15)00349-9openalex-snapshot
Grazoprevir plus elbasvir in treatment-naive and treatment-experienced patients with hepatitis C virus genotype 1 infection and stage 4–5 chronic kidney disease (the C-SURFER study): a combination phase 3 study
inferredcites →https://doi.org/10.1016/s0168-8278(15)30073-8openalex-snapshot
O059 : Long-term persistence of HCV NS5A variants after treatment with NS5A inhibitor ledipasvir
inferredcites →https://doi.org/10.1016/s2352-3018(15)00114-9openalex-snapshot
Efficacy and safety of grazoprevir (MK-5172) and elbasvir (MK-8742) in patients with hepatitis C virus and HIV co-infection (C-EDGE CO-INFECTION): a non-randomised, open-label trial
inferredcites →https://doi.org/10.1053/j.gastro.2016.04.003openalex-snapshot
Hepatitis C Virus Resistance to Direct-Acting Antiviral Drugs in Interferon-Free Regimens
inferredcites →https://doi.org/10.1053/j.gastro.2016.09.045openalex-snapshot
Effectiveness of Elbasvir and Grazoprevir Combination, With or Without Ribavirin, for Treatment-Experienced Patients With Chronic Hepatitis C Infection
inferredcites →https://doi.org/10.1053/j.gastro.2017.12.015openalex-snapshot
Efficacy of NS5A Inhibitors Against Hepatitis C Virus Genotypes 1–7 and Escape Variants
inferredcites →https://doi.org/10.1053/j.gastro.2018.02.017openalex-snapshot
HCV Genotype 6a Escape From and Resistance to Velpatasvir, Pibrentasvir, and Sofosbuvir in Robust Infectious Cell Culture Models
inferredcites →https://doi.org/10.1056/nejmoa1613512openalex-snapshot
Sofosbuvir, Velpatasvir, and Voxilaprevir for Previously Treated HCV Infection
inferredcites →https://doi.org/10.1093/cid/ciu696openalex-snapshot
Virologic Resistance Analysis From a Phase 2 Study of MK-5172 Combined With Pegylated Interferon/Ribavirin in Treatment-Naive Patients With Hepatitis C Virus Genotype 1 Infection
inferredcites →https://doi.org/10.1093/med/9780199609147.003.0027openalex-snapshot
Summary of product characteristics
inferredcites →https://doi.org/10.1111/hae.12533openalex-snapshot
Adherence to prophylaxis is associated with better outcomes in moderate and severe haemophilia: results of a patient survey
inferredcites →https://doi.org/10.1128/aac.00051-16openalex-snapshot
The Combination of Grazoprevir, a Hepatitis C Virus (HCV) NS3/4A Protease Inhibitor, and Elbasvir, an HCV NS5A Inhibitor, Demonstrates a High Genetic Barrier to Resistance in HCV Genotype 1a Replicons
inferredcites →https://doi.org/10.1128/aac.00324-12openalex-snapshot
MK-5172, a Selective Inhibitor of Hepatitis C Virus NS3/4a Protease with Broad Activity across Genotypes and Resistant Variants
inferredcites →https://doi.org/10.1128/aac.02494-12openalex-snapshot
Persistence of Resistant Variants in Hepatitis C Virus-Infected Patients Treated with the NS5A Replication Complex Inhibitor Daclatasvir
inferredcites →https://doi.org/10.1128/aac.02929-15openalex-snapshot
Hepatitis C Virus Genotype 1 to 6 Protease Inhibitor Escape Variants: In Vitro Selection, Fitness, and Resistance Patterns in the Context of the Infectious Viral Life Cycle
inferredcites →https://doi.org/10.3851/imp3177openalex-snapshot
Pooled Analysis of HCV Genotype 1 Resistance-Associated Substitutions in NS5A, NS3 and NS5B pre- and Post-Treatment with 12 Weeks of Daclatasvir, Asunaprevir and Beclabuvir
inferredcites →https://doi.org/10.5604/01.3001.0010.7532openalex-snapshot
Meta-Analysis of Grazoprevir plus Elbasvir for Treatment of Hepatitis C Virus Genotype 1 Infection
inferredcites →https://doi.org/10.7326/m15-0785openalex-snapshot
Grazoprevir–Elbasvir Combination Therapy for Treatment-Naive Cirrhotic and Noncirrhotic Patients With Chronic Hepatitis C Virus Genotype 1, 4, or 6 Infection
inferredcites →https://doi.org/10.7326/m16-0816openalex-snapshot
Elbasvir–Grazoprevir to Treat Hepatitis C Virus Infection in Persons Receiving Opioid Agonist Therapy

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4613660openalex-extracted
Prevalence of Drug Resistance Associated Substitutions in Hepatitis C-Infected Patients Whose WHO-Recommended Direct Acting Agents for Initial Treatment and Retreatment Fails: A Systematic Review and Meta-Analysis
inferred← citeshttps://doi.org/10.1002/9781683670438.mcm0115openalex-snapshot
Mechanisms of Resistance to Antiviral Agents
inferred← citeshttps://doi.org/10.1002/9781683674849.mcm0115openalex-snapshot
Mechanisms of Resistance to Antiviral Agents
inferred← citeshttps://doi.org/10.1007/978-3-030-03757-4_2openalex-snapshot
Laboratory and Molecular Diagnosis of Hepatitis C and Resistance Testing
inferred← citeshttps://doi.org/10.1016/j.ijid.2020.03.061openalex-snapshot
NS5A resistance – associated substitutions in chronic hepatitis C patients with direct acting antiviral treatment failure in Turkey
inferred← citeshttps://doi.org/10.1016/j.jhep.2020.11.017openalex-snapshot
Failure on voxilaprevir, velpatasvir, sofosbuvir and efficacy of rescue therapy
inferred← citeshttps://doi.org/10.1016/j.jhep.2021.03.004openalex-snapshot
Treatment failure with DAA therapy: Importance of resistance
inferred← citeshttps://doi.org/10.1016/j.jhep.2021.04.057openalex-snapshot
Linkage of resistance-associated substitutions in GT1 sofosbuvir + NS5A inhibitor failures treated with glecaprevir/pibrentasvir
inferred← citeshttps://doi.org/10.1016/j.jhep.2022.08.016openalex-snapshot
Long-term persistence of HCV resistance-associated substitutions after DAA treatment failure
inferred← citeshttps://doi.org/10.1038/s44259-025-00125-zopenalex-snapshot
Strategies and efforts in circumventing the emergence of antiviral resistance against conventional antivirals
inferred← citeshttps://doi.org/10.1093/cid/ciae431openalex-snapshot
Prevalence of Drug Resistance Associated Substitutions in Persons With Chronic Hepatitis C Infection and Virological Failure Following Initial or Re-treatment With Pan-genotypic Direct-Acting Antivirals: A Systematic Review and Meta-analysis
inferred← citeshttps://doi.org/10.1093/jac/dkaa091openalex-snapshot
Grazoprevir/elbasvir for the immediate treatment of recently acquired HCV genotype 1 or 4 infection in MSM
inferred← citeshttps://doi.org/10.1111/liv.15211openalex-snapshot
Durability of sustained virological response to glecaprevir/pibrentasvir and resistance development: A long‐term follow‐up study
inferred← citeshttps://doi.org/10.1128/aac.01269-19openalex-snapshot
Interplay of Amino Acid Residues at Positions 28 and 31 in NS5A Defines Resistance Pathways in Hepatitis C Virus Genotype 2
inferred← citeshttps://doi.org/10.1128/aac.01280-18openalex-snapshot
In Vitro Antiviral Profile of Ruzasvir, a Potent and Pangenotype Inhibitor of Hepatitis C Virus NS5A
inferred← citeshttps://doi.org/10.1155/2022/3556780openalex-snapshot
Treatment-Resistant Hepatitis C Viral Infection: A Case Report and Literature Review
inferred← citeshttps://doi.org/10.18470/1992-1098-2024-1-4openalex-snapshot
Genetic diversity of hepatitis C virus and the prevalence of resistance mutations to NS5A inhibitors in the Krasnoyarsk region
inferred← citeshttps://doi.org/10.22625/2072-6732-2018-10-4-30-36openalex-snapshot
Drug resistant variants of hepatitis C virus genotype 1b in Russia: analysis of aminoacid substitutions in NS5a and core proteins
inferred← citeshttps://doi.org/10.22625/2072-6732-2020-12-1-104-110openalex-snapshot
Eradication of hepatitits C virus in patient with cryoglobulinemic vasculitis and mutations D168E, L31V
inferred← citeshttps://doi.org/10.3390/biomedicines8040080openalex-snapshot
Factors Influencing the Prevalence of Resistance-Associated Substitutions in NS5A Protein in Treatment-Naive Patients with Chronic Hepatitis C
inferred← citeshttps://doi.org/10.3390/pathogens13080674openalex-snapshot
An Increase in the Prevalence of Clinically Relevant Resistance-Associated Substitutions in Four Direct-Acting Antiviral Regimens: A Study Using GenBank HCV Sequences
inferred← citeshttps://doi.org/10.3390/v11111004openalex-snapshot
Resistance Mutations A30K and Y93N Associated with Treatment Failure with Sofosbuvir and Daclatasvir for Hepatitis C Virus Infection Non-Responder Patients: Case Reports
inferred← citeshttps://doi.org/10.3390/v16081250openalex-snapshot
Pharmacophore-Assisted Covalent Docking Identifies a Potential Covalent Inhibitor for Drug-Resistant Genotype 3 Variants of Hepatitis C Viral NS3/4A Serine Protease
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