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TGF-β: Guardian of T Cell Function
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/j.ccr.2005.10.012openalex-snapshot
TGF-β directly targets cytotoxic T cell functions during tumor evasion of immune surveillance
inferredcites →https://doi.org/10.1016/j.cell.2012.05.031openalex-snapshot
Extrathymic Generation of Regulatory T Cells in Placental Mammals Mitigates Maternal-Fetal Conflict
inferredcites →https://doi.org/10.1016/j.immuni.2004.07.016openalex-snapshot
Suppression of IL7Rα Transcription by IL-7 and Other Prosurvival Cytokines
inferredcites →https://doi.org/10.1016/j.immuni.2006.01.001openalex-snapshot
TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells
inferredcites →https://doi.org/10.1016/j.immuni.2006.07.011openalex-snapshot
Transforming Growth Factor-β Controls Development, Homeostasis, and Tolerance of T Cells by Regulatory T Cell-Dependent and -Independent Mechanisms
inferredcites →https://doi.org/10.1016/j.immuni.2006.07.012openalex-snapshot
Cellular Mechanisms of Fatal Early-Onset Autoimmunity in Mice with the T Cell-Specific Targeting of Transforming Growth Factor-β Receptor
inferredcites →https://doi.org/10.1016/j.immuni.2007.03.014openalex-snapshot
T Cell-Produced Transforming Growth Factor-β1 Controls T Cell Tolerance and Regulates Th1- and Th17-Cell Differentiation
inferredcites →https://doi.org/10.1016/j.immuni.2009.04.020openalex-snapshot
Opposing Effects of TGF-β and IL-15 Cytokines Control the Number of Short-Lived Effector CD8+ T Cells
inferredcites →https://doi.org/10.1016/j.immuni.2009.06.015openalex-snapshot
Cell-Intrinsic Transforming Growth Factor-β Signaling Mediates Virus-Specific CD8+ T Cell Deletion and Viral Persistence In Vivo
inferredcites →https://doi.org/10.1016/j.immuni.2010.04.012openalex-snapshot
Transforming Growth Factor-β Signaling Curbs Thymic Negative Selection Promoting Regulatory T Cell Development
inferredcites →https://doi.org/10.1016/j.immuni.2011.02.021openalex-snapshot
Transcription Factor Smad-Independent T Helper 17 Cell Induction by Transforming-Growth Factor-β Is Mediated by Suppression of Eomesodermin
inferredcites →https://doi.org/10.1016/j.immuni.2011.03.005openalex-snapshot
Autocrine Transforming Growth Factor-β1 Promotes In Vivo Th17 Cell Differentiation
inferredcites →https://doi.org/10.1016/j.immuni.2011.04.019openalex-snapshot
T Cell Surveillance of Oncogene-Induced Prostate Cancer Is Impeded by T Cell-Derived TGF-β1 Cytokine
inferredcites →https://doi.org/10.1016/j.immuni.2012.08.008openalex-snapshot
Subsets of Nonclonal Neighboring CD4+ T Cells Specifically Regulate the Frequency of Individual Antigen-Reactive T Cells
inferredcites →https://doi.org/10.1016/j.immuni.2013.07.016openalex-snapshot
TGF-β Cytokine Signaling Promotes CD8+ T Cell Development and Low-Affinity CD4+ T Cell Homeostasis by Regulation of Interleukin-7 Receptor α Expression
inferredcites →https://doi.org/10.1016/j.molimm.2008.12.019openalex-snapshot
Properties and origin of human Th17 cells
inferredcites →https://doi.org/10.1016/s1074-7613(00)80170-3openalex-snapshot
Abrogation of TGFβ Signaling in T Cells Leads to Spontaneous T Cell Differentiation and Autoimmune Disease
inferredcites →https://doi.org/10.1038/359693a0openalex-snapshot
Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease
inferredcites →https://doi.org/10.1038/nature04753openalex-snapshot
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
inferredcites →https://doi.org/10.1038/nature04754openalex-snapshot
Transforming growth factor-β induces development of the TH17 lineage
inferredcites →https://doi.org/10.1038/nature06110openalex-snapshot
Loss of integrin αvβ8 on dendritic cells causes autoimmunity and colitis in mice
inferredcites →https://doi.org/10.1038/nature06878openalex-snapshot
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
inferredcites →https://doi.org/10.1038/nature08750openalex-snapshot
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
inferredcites →https://doi.org/10.1038/nature09447openalex-snapshot
Generation of pathogenic TH17 cells in the absence of TGF-β signalling
inferredcites →https://doi.org/10.1038/nature10772openalex-snapshot
Extrathymically generated regulatory T cells control mucosal TH2 inflammation
inferredcites →https://doi.org/10.1038/ni.1607openalex-snapshot
A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells
inferredcites →https://doi.org/10.1038/ni.1817openalex-snapshot
Mechanisms maintaining peripheral tolerance
inferredcites →https://doi.org/10.1038/ni.1840openalex-snapshot
Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells
inferredcites →https://doi.org/10.1038/ni.1997openalex-snapshot
Control of the development of CD8αα+ intestinal intraepithelial lymphocytes by TGF-β
inferredcites →https://doi.org/10.1038/ni.2292openalex-snapshot
Clonal deletion and the fate of autoreactive thymocytes that survive negative selection
inferredcites →https://doi.org/10.1038/ni.2319openalex-snapshot
TGF-β signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation
inferredcites →https://doi.org/10.1038/ni.2362openalex-snapshot
The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-β and suppresses TH2 differentiation
inferredcites →https://doi.org/10.1038/ni.2416openalex-snapshot
Induction and molecular signature of pathogenic TH17 cells
inferredcites →https://doi.org/10.1038/ni.2518openalex-snapshot
Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4+ T cell immunity
inferredcites →https://doi.org/10.1038/ni1391openalex-snapshot
Signals mediated by transforming growth factor-β initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease
inferredcites →https://doi.org/10.1038/ni1488openalex-snapshot
IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
inferredcites →https://doi.org/10.1038/ni1539openalex-snapshot
TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell–mediated pathology
inferredcites →https://doi.org/10.1038/ni1549openalex-snapshot
Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer
inferredcites →https://doi.org/10.1038/nm1001-1118openalex-snapshot
Immune-mediated eradication of tumors through the blockade of transforming growth factor-β signaling in T cells
inferredcites →https://doi.org/10.1038/nri1707openalex-snapshot
Central tolerance: learning self-control in the thymus
inferredcites →https://doi.org/10.1038/nri3007openalex-snapshot
The light and dark sides of intestinal intraepithelial lymphocytes
inferredcites →https://doi.org/10.1038/nri3369openalex-snapshot
Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions
inferredcites →https://doi.org/10.1053/j.gastro.2011.06.076openalex-snapshot
Preferential Expression of Integrin αvβ8 Promotes Generation of Regulatory T Cells by Mouse CD103+ Dendritic Cells
inferredcites →https://doi.org/10.1073/pnas.0707421104openalex-snapshot
Ulcerative colitis and autoimmunity induced by loss of myeloid αv integrins
inferredcites →https://doi.org/10.1073/pnas.0901944106openalex-snapshot
GARP (LRRC32) is essential for the surface expression of latent TGF-β on platelets and activated FOXP3 + regulatory T cells
inferredcites →https://doi.org/10.1073/pnas.1108352109openalex-snapshot
Requirements of transcription factor Smad-dependent and -independent TGF-β signaling to control discrete T-cell functions
inferredcites →https://doi.org/10.1073/pnas.1304498110openalex-snapshot
Excessive Th1 responses due to the absence of TGF-β signaling cause autoimmune diabetes and dysregulated Treg cell homeostasis
inferredcites →https://doi.org/10.1073/pnas.90.2.770openalex-snapshot
Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.
inferredcites →https://doi.org/10.1083/jcb.200611044openalex-snapshot
Absence of integrin-mediated TGFβ1 activation in vivo recapitulates the phenotype of TGFβ1-null mice
inferredcites →https://doi.org/10.1084/jem.191.7.1187openalex-snapshot
Disruption of T Cell Homeostasis in Mice Expressing a T Cell–Specific Dominant Negative Transforming Growth Factor β II Receptor
inferredcites →https://doi.org/10.1084/jem.20011956openalex-snapshot
The Transcription Factor T-bet Regulates Mucosal T Cell Activation in Experimental Colitis and Crohn's Disease
inferredcites →https://doi.org/10.1084/jem.20021170openalex-snapshot
Transforming Growth Factor β Blocks Tec Kinase Phosphorylation, Ca2+ Influx, and NFATc Translocation Causing Inhibition of T Cell Differentiation
inferredcites →https://doi.org/10.1084/jem.20070590openalex-snapshot
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism
inferredcites →https://doi.org/10.1084/jem.20070602openalex-snapshot
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
inferredcites →https://doi.org/10.1084/jem.20081666openalex-snapshot
Down-regulation of Gfi-1 expression by TGF-β is important for differentiation of Th17 and CD103+ inducible regulatory T cells
inferredcites →https://doi.org/10.1084/jem.20082286openalex-snapshot
Transforming growth factor β is dispensable for the molecular orchestration of Th17 cell differentiation
inferredcites →https://doi.org/10.1084/jem.20090127openalex-snapshot
iNKT cell development is orchestrated by different branches of TGF-β signaling
inferredcites →https://doi.org/10.1084/jem.20110308openalex-snapshot
T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse
inferredcites →https://doi.org/10.1084/jem.20112646openalex-snapshot
Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut
inferredcites →https://doi.org/10.1091/mbc.e11-12-1018openalex-snapshot
GARP regulates the bioavailability and activation of TGFβ
inferredcites →https://doi.org/10.1093/intimm/6.4.631openalex-snapshot
Differential effect of transforming growth factor-β1 on the activation of human naive and memory CD4+ T lymphocytes
inferredcites →https://doi.org/10.1146/annurev-immunol-020711-075035openalex-snapshot
Selection of Self-Reactive T Cells in the Thymus
inferredcites →https://doi.org/10.1146/annurev.immunol.24.021605.090737openalex-snapshot
TRANSFORMING GROWTH FACTOR-β REGULATION OF IMMUNE RESPONSES
inferredcites →https://doi.org/10.1146/annurev.immunol.25.022106.141623openalex-snapshot
Regulatory T Cells: Mechanisms of Differentiation and Function
inferredcites →https://doi.org/10.1172/jci43786openalex-snapshot
Expression of αvβ8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice
inferredcites →https://doi.org/10.1172/jci43796openalex-snapshot
αv Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice
inferredcites →https://doi.org/10.1182/blood-2006-05-025676openalex-snapshot
Dysregulation of IL-15-mediated T-cell homeostasis in TGF-β dominant-negative receptor transgenic mice
inferredcites →https://doi.org/10.1371/journal.pone.0042268openalex-snapshot
TGF-β Sensitivity Restrains CD8+ T Cell Homeostatic Proliferation by Enforcing Sensitivity to IL-7 and IL-15
inferredcites →https://doi.org/10.4049/jimmunol.0904100openalex-snapshot
Smad2 and Smad3 Are Redundantly Essential for the TGF-β–Mediated Regulation of Regulatory T Plasticity and Th1 Development
inferredcites →https://doi.org/10.4049/jimmunol.1201415openalex-snapshot
Cell-Intrinsic Abrogation of TGF-β Signaling Delays but Does Not Prevent Dysfunction of Self/Tumor-Specific CD8 T Cells in a Murine Model of Autochthonous Prostate Cancer
inferredcites →https://doi.org/10.4049/jimmunol.1300397openalex-snapshot
Truncated Form of TGF-βRII, But Not Its Absence, Induces Memory CD8+ T Cell Expansion and Lymphoproliferative Disorder in Mice
inferredcites →https://doi.org/10.4049/jimmunol.155.2.609openalex-snapshot
Transforming growth factor β 1 costimulated growth and regulatory function of staphylococcal enterotoxin B-responsive CD8+ T cells
inferredcites →https://doi.org/10.4049/jimmunol.165.9.4773openalex-snapshot
Cutting Edge: TGF-β Inhibits Th Type 2 Development Through Inhibition of GATA-3 Expression
inferredcites →https://doi.org/10.4049/jimmunol.172.1.40openalex-snapshot
A Role for TCR Affinity in Regulating Naive T Cell Homeostasis
inferredcites →https://doi.org/10.4049/jimmunol.179.1.71openalex-snapshot
TGF-β1 Regulates Antigen-Specific CD4+ T Cell Responses in the Periphery
inferredcites →https://doi.org/10.4161/onci.1.2.18481openalex-snapshot
Tgf-β1 produced by activated CD4 + T Cells Antagonizes T Cell Surveillance of Tumor Development
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Multifaceted TGF‐β signaling, a master regulator: From bench‐to‐bedside, intricacies, and complexities
inferred← citeshttps://doi.org/10.1002/cti2.1223openalex-snapshot
Rapamycin and abundant TCR stimulation are required for the generation of stable human induced regulatory T cells
inferred← citeshttps://doi.org/10.1002/ijc.33859openalex-snapshot
NKG2A is a late immune checkpoint on CD8 T cells and marks repeated stimulation and cell division
inferred← citeshttps://doi.org/10.1002/jca.21466openalex-snapshot
Granulocytes and monocytes apheresis induces upregulation of TGFβ1 in patients with active ulcerative colitis: A possible involvement of soluble HLA‐I
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A Snapshot of Cytokine Dynamics: A Fine Balance Between Health and Disease
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Consumption of selenium‐enriched broccoli increases cytokine production in human peripheral blood mononuclear cells stimulated ex vivo, a preliminary human intervention study
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Transforming Growth Factor‐Beta Signaling in Cancer: Therapeutic Implications, Challenges, and Pathways to Progress
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Plasminogen Activator Urokinase Receptor Implies Immunosuppressive Features and Acts as an Unfavorable Prognostic Biomarker in Glioma
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Spontaneous development of an autoimmune hepatitis – primary biliary cholangitis overlap syndrome in dnTGFβRII Aire−/− mice
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Helper T Cell Plasticity: Impact of Extrinsic and Intrinsic Signals on Transcriptomes and Epigenomes
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Immunoregulatory Myeloid Cells in the Tumor Microenvironment
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Immune Checkpoint Combinations with Inflammatory Pathway Modulators
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Cytokine and Chemokine-Based Regulation of Natural Killer Cells
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Targeting TGF-β signaling in glioblastoma: therapeutic implications and novel drug development strategies
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EGR1 Mediated Reduction of Fibroblast Secreted-TGF-β1 Exacerbated CD8+ T Cell Inflammation and Migration in Vitiligo
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The role of transforming growth factor beta in thyroid autoimmunity: current knowledge and future perspectives
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Modeling LSD1-Mediated Tumor Stagnation
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Cellular and Molecular Detection of Multi-doses of Ionizing Radiation-Induced Immunomodulatory Response
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HTLV-1 subgroups associated with the risk of HAM/TSP are related to viral and host gene expression in peripheral blood mononuclear cells, independent of the transactivation functions of the viral factors
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Synergistic combination of oncolytic virotherapy with CAR T-cell therapy
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IL-27 in patients with Chikungunya fever: A possible chronicity biomarker?
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Loss of the proprotein convertase Furin in T cells represses mammary tumorigenesis in oncogene-driven triple negative breast cancer
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Tumor-tagging by oncolytic viruses: A novel strategy for CAR-T therapy against solid tumors
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TGFβ restricts expansion, survival, and function of T cells within the tuberculous granuloma
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Differential immune gene expression in rainbow trout, Oncorhynchus mykiss (walbaum), exposed to five pathogens: Aeromonas salmonicida, Flavobacterium psychrophilum, Vibrio anguillarum, Yersinia ruckeri and Ichthyophthirius multifiliis
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An integrated bioinformatics and machine learning-based approach to depict key immunological players associated with candidemia during immunodeficiency
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Current progress in the elucidation of Acute Myeloid Leukemia (AML) immune landscapes
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Lack of evidence supporting a role of IFN-β and TGF-β in differential polarization of Bordetella pertussis specific-T cell responses
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The TGF-β superfamily in dendritic cell biology
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Correlates of Protection Against SIVmac251 Infection in Rhesus Macaques Immunized With Chimpanzee-Derived Adenovirus Vectors
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Down-regulation of Gremlin1 inhibits inflammatory response and vascular permeability in chronic idiopathic urticaria through suppression of TGF-β signaling pathway
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Polymorphisms in the TGFB1 and FOXP3 genes are associated with the presence of antinuclear antibodies in chronic hepatitis C
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Chimeric antigen receptor-modified T cells therapy in prostate cancer: A comprehensive review on the current state and prospects
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Human macrophage polarization in vitro: Maturation and activation methods compared
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Tumor-Associated Macrophages: From Mechanisms to Therapy
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Low expression of RGL4 is associated with a poor prognosis and immune infiltration in lung adenocarcinoma patients
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p38 inhibition enhances TCR-T cell function and antagonizes the immunosuppressive activity of TGF-β
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Immunotherapy of Cancer by Targeting Regulatory T cells
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Vitamin D exerts endogenous control over TH2 cell fate and immune plasticity
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GPR82-mediated activation of TGF-β/SMAD signaling contributes to CD8+ T cell dysfunction in HBV-ACLF
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Emerging roles of astrocytes as immune effectors in the central nervous system
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Tissue remodeling in eosinophilic esophagitis
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A unique CD8+ T lymphocyte signature in pediatric type 1 diabetes
inferred← citeshttps://doi.org/10.1016/j.jaut.2022.102870openalex-snapshot
Abnormalities of T cells in systemic lupus erythematosus: new insights in pathogenesis and therapeutic strategies
inferred← citeshttps://doi.org/10.1016/j.jbc.2022.102843openalex-snapshot
TGF-β1 suppresses the T-cell response in teleost fish by initiating Smad3- and Foxp3-mediated transcriptional networks
inferred← citeshttps://doi.org/10.1016/j.jdermsci.2019.04.008openalex-snapshot
Keratinocyte-derived TGFβ is not required to maintain skin immune homeostasis
inferred← citeshttps://doi.org/10.1016/j.jneuroim.2014.03.014openalex-snapshot
Increasing serum levels of vitamin A, D and E are associated with alterations of different inflammation markers in patients with multiple sclerosis
inferred← citeshttps://doi.org/10.1016/j.jneuroim.2015.02.006openalex-snapshot
Analysis of apoptosis-related genes in patients with clinically isolated syndrome and their association with conversion to multiple sclerosis
inferred← citeshttps://doi.org/10.1016/j.jneuroim.2015.04.007openalex-snapshot
The role of laquinimod in modulation of the immune response in relapsing–remitting multiple sclerosis: Lessons from gene expression signatures
inferred← citeshttps://doi.org/10.1016/j.joca.2024.12.002openalex-snapshot
A programmable arthritis-specific receptor for guided articular cartilage regenerative medicine
inferred← citeshttps://doi.org/10.1016/j.lfs.2022.120643openalex-snapshot
Identification of EPZ004777 and FG2216 as inhibitors of TGF-β1 induced Treg cells by screening a library of epigenetic compounds
inferred← citeshttps://doi.org/10.1016/j.lfs.2022.121011openalex-snapshot
TGF-β at the crossroads of multiple prognosis in breast cancer, and beyond
inferred← citeshttps://doi.org/10.1016/j.mce.2014.12.024openalex-snapshot
The role of TGF-β/Smad signaling in dopamine agonist-resistant prolactinomas
inferred← citeshttps://doi.org/10.1016/j.micinf.2014.08.002openalex-snapshot
Effects of soluble extracts from Leishmania infantum promastigotes, Toxoplasma gondii tachyzoites on TGF-β mediated pathways in activated CD4+ T lymphocytes
inferred← citeshttps://doi.org/10.1016/j.mtbio.2022.100432openalex-snapshot
Cell-free immunomodulatory biomaterials mediated in situ periodontal multi-tissue regeneration and their immunopathophysiological processes
inferred← citeshttps://doi.org/10.1016/j.mucimm.2026.02.005openalex-snapshot
Temporal Dissection of TGF-β signaling reveals differential impact during female reproductive mucosal CD8 resident memory T cell differentiation
inferred← citeshttps://doi.org/10.1016/j.omto.2021.03.014openalex-snapshot
Secretion of bispecific protein of anti-PD-1 fused with TGF-β trap enhances antitumor efficacy of CAR-T cell therapy
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2022.108211openalex-snapshot
The roles of TGF-β and VEGF pathways in the suppression of antitumor immunity in melanoma and other solid tumors
inferred← citeshttps://doi.org/10.1016/j.phrs.2019.01.038openalex-snapshot
Transforming growth factor-β in pancreatic diseases: Mechanisms and therapeutic potential
inferred← citeshttps://doi.org/10.1016/j.prp.2024.155428openalex-snapshot
Core needle biopsy changes the expression of TGFβ1 and TGFβRII at protein level, and the distribution of CD4 and CD8 positive T cells in primary breast cancer
inferred← citeshttps://doi.org/10.1016/j.smim.2019.03.001openalex-snapshot
Tissue-resident cytotoxic innate lymphoid cells in tumor immunosurveillance
inferred← citeshttps://doi.org/10.1016/j.soc.2019.02.005openalex-snapshot
Induced Pluripotent Stem Cell-Derived T Cells for Cancer Immunotherapy
inferred← citeshttps://doi.org/10.1016/j.trecan.2021.06.007openalex-snapshot
Immunity beyond cancer cells: perspective from tumor tissue
inferred← citeshttps://doi.org/10.1016/j.trim.2017.08.004openalex-snapshot
Pre-transplant infusion of donor-derived dendritic cells maintained at the immature stage by sinomenine increases splenic Foxp3 + Tregs in recipient rats after renal allotransplantation
inferred← citeshttps://doi.org/10.1016/j.waojou.2019.100058openalex-snapshot
Transforming growth factor-β1 and eosinophil-derived neurotoxins contribute to the development of work-related respiratory symptoms in bakery workers
inferred← citeshttps://doi.org/10.1016/j.xcrm.2023.101053openalex-snapshot
Tissue-resident memory CAR T cells with stem-like characteristics display enhanced efficacy against solid and liquid tumors
inferred← citeshttps://doi.org/10.1016/j.xcrm.2023.101080openalex-snapshot
Steering CAR T cell epigenetic programs by tweaking manufacturing protocol
inferred← citeshttps://doi.org/10.1016/j.yexcr.2018.07.029openalex-snapshot
Interaction of cancer cell-derived Foxp3 and tumor microenvironment in human tongue squamous cell carcinoma
inferred← citeshttps://doi.org/10.1016/s1875-5364(22)60179-1openalex-snapshot
Panax notoginseng saponins prevent colitis-associated colorectal cancer via inhibition IDO1 mediated immune regulation
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.7b01612openalex-snapshot
Design, Synthesis, and Structure–Activity Relationship Study of 2-Oxo-3,4-dihydropyrimido[4,5-d]pyrimidines as New Colony Stimulating Factor 1 Receptor (CSF1R) Kinase Inhibitors
inferred← citeshttps://doi.org/10.1021/acsomega.3c07098openalex-snapshot
Proteome of Personalized Tissue-Engineered Veins
inferred← citeshttps://doi.org/10.1021/bk-2015-1200.ch018openalex-snapshot
Toward a Synthetic View of the Therapeutic Use of Cerium Oxide Nanoparticles for the Treatment of Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.1038/icb.2016.98openalex-snapshot
Impact of T‐cell‐specific Smad4 deficiency on the development of autoimmune diabetes in NOD mice
inferred← citeshttps://doi.org/10.1038/mi.2016.100openalex-snapshot
Predominance of weakly cytotoxic, T-betLowEomesNeg CD8+ T-cells in human gastrointestinal mucosa: implications for HIV infection
inferred← citeshttps://doi.org/10.1038/mi.2017.96openalex-snapshot
Detection of HIV-1-specific gastrointestinal tissue resident CD8+ T-cells in chronic infection
inferred← citeshttps://doi.org/10.1038/mto.2016.6openalex-snapshot
Chimeric antigen receptor T-cell therapy for solid tumors
inferred← citeshttps://doi.org/10.1038/npjbcancer.2015.25openalex-snapshot
Tumor-associated macrophages: unwitting accomplices in breast cancer malignancy
inferred← citeshttps://doi.org/10.1038/s41392-023-01452-1openalex-snapshot
Macrophages in immunoregulation and therapeutics
inferred← citeshttps://doi.org/10.1038/s41392-026-02710-8openalex-snapshot
Immune modulatory vaccines targeting tumor microenvironment antigens: recent advances in oncology and beyond
inferred← citeshttps://doi.org/10.1038/s41420-023-01356-7openalex-snapshot
Targeting tumor-associated macrophages in hepatocellular carcinoma: biology, strategy, and immunotherapy
inferred← citeshttps://doi.org/10.1038/s41420-024-02254-2openalex-snapshot
Phytochemical-mediated efferocytosis and autophagy in inflammation control
inferred← citeshttps://doi.org/10.1038/s41467-023-43656-7openalex-snapshot
CAR+ and CAR− T cells share a differentiation trajectory into an NK-like subset after CD19 CAR T cell infusion in patients with B cell malignancies
inferred← citeshttps://doi.org/10.1038/s41467-024-45555-xopenalex-snapshot
TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo
inferred← citeshttps://doi.org/10.1038/s41467-024-51442-2openalex-snapshot
The TGFβ type I receptor kinase inhibitor vactosertib in combination with pomalidomide in relapsed/refractory multiple myeloma: a phase 1b trial
inferred← citeshttps://doi.org/10.1038/s41514-023-00111-7openalex-snapshot
Effects of an aged tissue niche on the immune potency of dendritic cells using simulated microgravity
inferred← citeshttps://doi.org/10.1038/s41569-021-00646-wopenalex-snapshot
Transforming growth factor-β in myocardial disease
inferred← citeshttps://doi.org/10.1038/s41577-019-0240-6openalex-snapshot
Efferocytosis in health and disease
inferred← citeshttps://doi.org/10.1038/s41584-022-00843-yopenalex-snapshot
TGFβ priming promotes TNF-induced bone erosion: a promising new target in RA?
inferred← citeshttps://doi.org/10.1038/s41586-020-2836-1openalex-snapshot
TGF-β suppresses type 2 immunity to cancer
inferred← citeshttps://doi.org/10.1038/s41598-018-30466-xopenalex-snapshot
A cancer vaccine approach for personalized treatment of Lynch Syndrome
inferred← citeshttps://doi.org/10.1038/s41598-019-51092-1openalex-snapshot
Concentrates of two subsets of extracellular vesicles from cow’s milk modulate symptoms and inflammation in experimental colitis
inferred← citeshttps://doi.org/10.1038/s41598-020-57772-7openalex-snapshot
Positive and negative cooperativity of TNF and Interferon-γ in regulating synovial fibroblast function and B cell survival in fibroblast/B cell co-cultures
inferred← citeshttps://doi.org/10.1038/s41598-020-76130-1openalex-snapshot
Regulatory (FoxP3+) T cells and TGF-β predict the response to anti-PD-1 immunotherapy in patients with non-small cell lung cancer
inferred← citeshttps://doi.org/10.1038/s41598-021-85637-0openalex-snapshot
The effects of the miR-21/SMAD7/TGF-β pathway on Th17 cell differentiation in COPD
inferred← citeshttps://doi.org/10.1038/s41598-025-16002-8openalex-snapshot
Label-free estimation of regulatory T cell activation markers using Raman spectroscopy with machine learning
inferred← citeshttps://doi.org/10.1038/s42003-021-02773-zopenalex-snapshot
Isoform specific anti-TGFβ therapy enhances antitumor efficacy in mouse models of cancer
inferred← citeshttps://doi.org/10.1038/s42003-023-04555-1openalex-snapshot
Lipid nanoparticles (LNP) induce activation and maturation of antigen presenting cells in young and aged individuals
inferred← citeshttps://doi.org/10.1038/srep07583openalex-snapshot
Cardiac endothelial cell-derived exosomes induce specific regulatory B cells
inferred← citeshttps://doi.org/10.1051/parasite/2014051openalex-snapshot
Immune modulation by helminth parasites of ruminants: implications for vaccine development and host immune competence
inferred← citeshttps://doi.org/10.1053/j.gastro.2018.10.023openalex-snapshot
Alternative Splice Forms of CYLD Mediate Ubiquitination of SMAD7 to Prevent TGFB Signaling and Promote Colitis
inferred← citeshttps://doi.org/10.1073/pnas.1706356114openalex-snapshot
Foxp3-independent mechanism by which TGF-β controls peripheral T cell tolerance
inferred← citeshttps://doi.org/10.1074/mcp.m115.056036openalex-snapshot
The Pathogenesis of the Demyelinating Form of Guillain-Barre Syndrome (GBS): Proteo-peptidomic and Immunological Profiling of Physiological Fluids
inferred← citeshttps://doi.org/10.1080/08923973.2017.1386212openalex-snapshot
Artesunate enhances γδ T-cell-mediated antitumor activity through augmenting γδ T-cell function and reversing immune escape of HepG2 cells
inferred← citeshttps://doi.org/10.1080/14728222.2020.1744568openalex-snapshot
TGF-beta: a master immune regulator
inferred← citeshttps://doi.org/10.1080/21505594.2020.1726569openalex-snapshot
Balancing in a black box: Potential immunomodulatory roles for TGF-β signaling during blood-stage malaria
inferred← citeshttps://doi.org/10.1080/2162402x.2015.1016700openalex-snapshot
Reprogramming the tumor microenvironment: tumor-induced immunosuppressive factors paralyze T cells
inferred← citeshttps://doi.org/10.1084/jem.20210777openalex-snapshot
Arkadia-SKI/SnoN signaling differentially regulates TGF-β–induced iTreg and Th17 cell differentiation
inferred← citeshttps://doi.org/10.1093/ecco-jcc/jjv216openalex-snapshot
Lamina Propria CD4+LAP+ Regulatory T Cells Are Increased in Active Ulcerative Colitis but Show Increased IL-17 Expression and Reduced Suppressor Activity
inferred← citeshttps://doi.org/10.1093/jimmun/vkag099openalex-snapshot
Congenital cytomegalovirus infection drives oligoclonal expansion of cytotoxic γδ T cells from early fetal progenitors
inferred← citeshttps://doi.org/10.1097/mot.0000000000000688openalex-snapshot
Immune responses towards bioengineered tissues and strategies to control them
inferred← citeshttps://doi.org/10.1097/mpa.0000000000001960openalex-snapshot
Toll-Like Receptor 3 Is Critical to the Pancreatic Islet Milieu That Is Required for Coxsackievirus B4–Induced Type 1 Diabetes in Female Nonobese Diabetic Mice
inferred← citeshttps://doi.org/10.1097/qad.0000000000003716openalex-snapshot
Mycobacterium tuberculosis-induced monocyte transcriptional responses associated with resistance to tuberculin skin test/interferon-γ release assay conversion in people with HIV
inferred← citeshttps://doi.org/10.1097/tp.0000000000002370openalex-snapshot
Rethinking Regenerative Medicine From a Transplant Perspective (and Vice Versa)
inferred← citeshttps://doi.org/10.1101/2020.12.15.422949openalex-snapshot
Microbiome and Metabolome driven differentiation of TGF-β producing Tregs leads to Senescence and HIV latency
inferred← citeshttps://doi.org/10.1101/2022.03.29.22273013openalex-snapshot
CAR + and CAR - T cells differentiate into an NK-like subset that is associated with increased inflammatory cytokines following infusion
inferred← citeshttps://doi.org/10.1101/2022.08.14.503915openalex-snapshot
Expression QTLs in single-cell sequencing data
inferred← citeshttps://doi.org/10.1101/2024.05.14.594150openalex-snapshot
EZH2-driven immune evasion at disease presentation defines a targetable high-risk subset of acute leukemia exemplified by t(16;21) FUS::ERG AML
inferred← citeshttps://doi.org/10.1101/2024.06.02.597009openalex-snapshot
A dominant role of TGFβ in regulating T-cell size and physiology
inferred← citeshttps://doi.org/10.1101/2025.06.16.659752openalex-snapshot
Characterisation of distinct senescent-like T cell populations during healthy and unhealthy ageing
inferred← citeshttps://doi.org/10.1101/2025.09.26.678886openalex-snapshot
Multi-omics integration at cell type resolution uncovers gene-metabolite mechanisms underlying osteoarthritis heterogeneity
inferred← citeshttps://doi.org/10.1101/2025.11.20.689355openalex-snapshot
Congenital CMV infection drives oligoclonal expansion of cytotoxic γδ T cells from early fetal progenitors
inferred← citeshttps://doi.org/10.1101/cshperspect.a022236openalex-snapshot
Regulation of the Immune Response by TGF-β: From Conception to Autoimmunity and Infection
inferred← citeshttps://doi.org/10.1111/cas.14911openalex-snapshot
AKT3 is a key regulator of head and neck squamous cell carcinoma
inferred← citeshttps://doi.org/10.1111/cea.12453openalex-snapshot
Maternal diet and its influence on the development of allergic disease
inferred← citeshttps://doi.org/10.1111/cei.12351openalex-snapshot
Post-traumatic immunosuppression is reversed by anti-coagulated salvaged blood transfusion: deductions from studying immune status after knee arthroplasty
inferred← citeshttps://doi.org/10.1111/cei.13194openalex-snapshot
From stability to dynamics: understanding molecular mechanisms of regulatory T cells throughFoxp3transcriptional dynamics
inferred← citeshttps://doi.org/10.1111/febs.17234openalex-snapshot
Therapeutic targeting of TGF ‐β in lung cancer
inferred← citeshttps://doi.org/10.1111/imr.12706openalex-snapshot
The group 2 innate lymphoid cell ( ILC 2) regulatory network and its underlying mechanisms
inferred← citeshttps://doi.org/10.1111/imr.70119openalex-snapshot
Mixed Signals: T Cells as Architects of IgE Immunity
inferred← citeshttps://doi.org/10.1111/resp.14541openalex-snapshot
Overexpression of SMAD7 improves the function of EGFR ‐targeted human CAR‐T cells against non‐small‐cell lung cancer
inferred← citeshttps://doi.org/10.1111/tri.13068openalex-snapshot
Regenerative immunology: the immunological reaction to biomaterials
inferred← citeshttps://doi.org/10.1111/vco.12459openalex-snapshot
Metastatic immune infiltrates correlate with those of the primary tumour in canine osteosarcoma
inferred← citeshttps://doi.org/10.1126/sciadv.adn9857openalex-snapshot
Multi-armored allogeneic MUC1 CAR T cells enhance efficacy and safety in triple-negative breast cancer
inferred← citeshttps://doi.org/10.1126/sciimmunol.abi4919openalex-snapshot
Batf-mediated epigenetic control of effector CD8 + T cell differentiation
inferred← citeshttps://doi.org/10.1136/jitc-2022-005433openalex-snapshot
Selective targeting of GARP-LTGFβ axis in the tumor microenvironment augments PD-1 blockade via enhancing CD8 + T cell antitumor immunity
inferred← citeshttps://doi.org/10.1146/annurev-med-062315-120245openalex-snapshot
CAR T Cell Therapy for Solid Tumors
inferred← citeshttps://doi.org/10.1152/physrev.00012.2025openalex-snapshot
Crossroads between autoimmunity and cancer: underlying mechanisms and clinical implications
inferred← citeshttps://doi.org/10.1155/2020/8892189openalex-snapshot
Human Mesenchymal Stem Cells: The Present Alternative for High-Incidence Diseases, Even SARS-Cov-2
inferred← citeshttps://doi.org/10.1158/0008-5472.can-19-3584openalex-snapshot
ERRα Expression in Bone Metastases Leads to an Exacerbated Antitumor Immune Response
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-21-0573openalex-snapshot
Genome-Wide miRNA Expression Profiling of Molecular Subgroups of Peripheral T-cell Lymphoma
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-23-3841openalex-snapshot
Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma
inferred← citeshttps://doi.org/10.1158/2159-8290.cd-22-0876openalex-snapshot
Context-Specific Determinants of the Immunosuppressive Tumor Microenvironment in Pancreatic Cancer
inferred← citeshttps://doi.org/10.1167/iovs.14-14578openalex-snapshot
Elevated Transforming Growth Factor β1 in Plasma of Primary Open-Angle Glaucoma Patients
inferred← citeshttps://doi.org/10.1172/jci128644openalex-snapshot
Hedgehog signaling promotes tumor-associated macrophage polarization to suppress intratumoral CD8+ T cell recruitment
inferred← citeshttps://doi.org/10.1177/11795549221120708openalex-snapshot
Igniting Hope for Tumor Immunotherapy: Promoting the “Hot and Cold” Tumor Transition
inferred← citeshttps://doi.org/10.1177/2515135518768769openalex-snapshot
Novel tumour antigens and the development of optimal vaccine design
inferred← citeshttps://doi.org/10.1182/bloodadvances.2020004142openalex-snapshot
Severe cytokine release syndrome is associated with hematologic toxicity following CD19 CAR T-cell therapy
inferred← citeshttps://doi.org/10.1182/bloodadvances.2023012463openalex-snapshot
Extracorporeal photopheresis as a promising strategy for the treatment of graft-versus-host disease after CAR T-cell therapy
inferred← citeshttps://doi.org/10.1186/2045-3701-5-2openalex-snapshot
Quantitative proteomic analysis of single or fractionated radiation-induced proteins in human breast cancer MDA-MB-231 cells
inferred← citeshttps://doi.org/10.1186/s11658-023-00421-4openalex-snapshot
Outside the limit: questioning the distance restrictions for cooperative miRNA binding sites
inferred← citeshttps://doi.org/10.1186/s12864-023-09844-xopenalex-snapshot
Genome-wide association study identifies genetic variants underlying footrot in Portuguese Merino sheep
inferred← citeshttps://doi.org/10.1186/s12917-023-03760-8openalex-snapshot
Knock down of transforming growth factor beta improves expressions of co-stimulatory molecules, type I interferon-regulated genes, and pro-inflammatory cytokine in PRRSV-inoculated monocyte-derived macrophages
inferred← citeshttps://doi.org/10.1186/s12967-023-04716-0openalex-snapshot
Macrophage metabolism, phenotype, function, and therapy in hepatocellular carcinoma (HCC)
inferred← citeshttps://doi.org/10.1186/s13020-021-00453-yopenalex-snapshot
Honeysuckle-derived microRNA2911 inhibits tumor growth by targeting TGF-β1
inferred← citeshttps://doi.org/10.1186/s13045-021-01053-xopenalex-snapshot
Novel therapies emerging in oncology to target the TGF-β pathway
inferred← citeshttps://doi.org/10.1186/s13045-024-01559-0openalex-snapshot
Deciphering the performance of macrophages in tumour microenvironment: a call for precision immunotherapy
inferred← citeshttps://doi.org/10.1186/s13059-021-02262-wopenalex-snapshot
Integrative analyses of TEDDY Omics data reveal lipid metabolism abnormalities, increased intracellular ROS and heightened inflammation prior to autoimmunity for type 1 diabetes
inferred← citeshttps://doi.org/10.1186/s40364-023-00537-xopenalex-snapshot
The CAR macrophage cells, a novel generation of chimeric antigen-based approach against solid tumors
inferred← citeshttps://doi.org/10.1189/jlb.2hima1214-578ropenalex-snapshot
TCR signaling intensity controls CD8+ T cell responsiveness to TGF-β
inferred← citeshttps://doi.org/10.12688/f1000research.3-37.v1openalex-snapshot
The second touch hypothesis: T cell activation, homing and polarization
inferred← citeshttps://doi.org/10.12701/yujm.2017.34.2.149openalex-snapshot
Role of the transforming growth factor (TGF)-β1 and TGF-β1 signaling pathway on the pathophysiology of respiratory pneumococcal infections
inferred← citeshttps://doi.org/10.1371/journal.pbio.2005046openalex-snapshot
The human lymph node microenvironment unilaterally regulates T-cell activation and differentiation
inferred← citeshttps://doi.org/10.1371/journal.pone.0123650openalex-snapshot
Drak2 Does Not Regulate TGF-β Signaling in T Cells
inferred← citeshttps://doi.org/10.1371/journal.pone.0128341openalex-snapshot
Septic Shock in Advanced Age: Transcriptome Analysis Reveals Altered Molecular Signatures in Neutrophil Granulocytes
inferred← citeshttps://doi.org/10.14393/ufu.te.2018.904openalex-snapshot
Efeitos imunomodulatórios de peptídeos com ação semelhante à IL-10 e ao TGF-β1 em processos inflamatórios
inferred← citeshttps://doi.org/10.14712/23362936.2022.15openalex-snapshot
Disturbance in Serum Levels of IL-17 and TGF-β1 and in Gene Expression of ROR-γt and FOX-P3 Is Associated with Pathogenicity of Systematic Lupus Erythematosus
inferred← citeshttps://doi.org/10.15036/arerugi.64.824openalex-snapshot
TGFβ (Transforming growth factor-β)
inferred← citeshttps://doi.org/10.1590/1806-9282.20230683openalex-snapshot
Effect of Laurus nobilis on bacteria and human transforming growth factor-β1
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