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Characterization of Platelet–Monocyte Complexes in HIV-1–Infected Individuals: Possible Role in HIV-Associated Neuroinflammation

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/archneurol.2010.84openalex-snapshot
Food Combination and Alzheimer Disease Risk
inferredcites →https://doi.org/10.1002/ana.22053openalex-snapshot
Human immunodeficiency virus‐associated neurocognitive disorders: Mind the gap
inferredcites →https://doi.org/10.1002/ana.410380510openalex-snapshot
Immunocytochemical quantitation of human immunodeficiency virus in the brain: Correlations with dementia
inferredcites →https://doi.org/10.1002/eji.1830251232openalex-snapshot
CD14 low CD16 high : A cytokine‐producing monocyte subset which expands during human immunodeficiency virus infection
inferredcites →https://doi.org/10.1006/viro.2002.1399openalex-snapshot
Involvement of Integrin αvβ3 in the Pathogenesis of Human Immunodeficiency Virus Type 1 Infection in Monocytes
inferredcites →https://doi.org/10.1016/j.jviromet.2012.02.005openalex-snapshot
Detection of circulating platelet–monocyte complexes in persons infected with human immunodeficiency virus type-1
inferredcites →https://doi.org/10.1016/j.thromres.2007.07.016openalex-snapshot
Circulating platelet–leukocyte aggregates: A marker of microvascular injury in diabetic patients
inferredcites →https://doi.org/10.1016/s0140-6736(96)10178-1openalex-snapshot
Unique monocyte subset in patients with AIDS dementia
inferredcites →https://doi.org/10.1016/s0735-1097(01)01485-1openalex-snapshot
Circulating monocyte-platelet aggregates are an early marker of acute myocardial infarction
inferredcites →https://doi.org/10.1038/89490openalex-snapshot
CXCR4-activated astrocyte glutamate release via TNFα: amplification by microglia triggers neurotoxicity
inferredcites →https://doi.org/10.1038/sj.cdd.4401623openalex-snapshot
HIV-1 infection and AIDS: consequences for the central nervous system
inferredcites →https://doi.org/10.1073/pnas.96.14.8212openalex-snapshot
Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis
inferredcites →https://doi.org/10.1080/135502801753248114openalex-snapshot
CNS invasion by CD14+/CD16+ peripheral blood-derived monocytes in HIV dementia: perivascular accumulation and reservoir of HIV infection
inferredcites →https://doi.org/10.1080/13550280802132857openalex-snapshot
Monocyte/macrophage trafficking in acquired immunodeficiency syndrome encephalitis: Lessons from human and nonhuman primate studies
inferredcites →https://doi.org/10.1083/jcb.142.2.595openalex-snapshot
A Role for the αvβ3 Integrin in the Transmigration of Monocytes
inferredcites →https://doi.org/10.1084/jem.20022156openalex-snapshot
Fractalkine Preferentially Mediates Arrest and Migration of CD16+ Monocytes
inferredcites →https://doi.org/10.1096/fasebj.12.1.79openalex-snapshot
Enhanced activation of platelets with abnormal release of RANTES in human immunodeficiency virus type 1 infection
inferredcites →https://doi.org/10.1097/00005072-198611000-00003openalex-snapshot
Neuropathology of Acquired Immunodeficiency Syndrome (AIDS)
inferredcites →https://doi.org/10.1097/coh.0b013e328347876copenalex-snapshot
Cardiovascular disease in HIV infection
inferredcites →https://doi.org/10.1097/qai.0b013e31828a292copenalex-snapshot
Aspirin Attenuates Platelet Activation and Immune Activation in HIV-1-Infected Subjects on Antiretroviral Therapy
inferredcites →https://doi.org/10.1111/1755-5922.12021openalex-snapshot
Prasugrel Reduces Agonists′ Inducible Platelet Activation and Leukocyte–Platelet Interaction more efficiently than Clopidogrel
inferredcites →https://doi.org/10.1111/j.1399-0012.2011.01406.xopenalex-snapshot
Surveillance of megakaryocytic function by measurement of CD61‐exposing microparticles in allogeneic hematopoietic stem cell recipients
inferredcites →https://doi.org/10.1111/j.1468-1293.2012.00996.xopenalex-snapshot
Relative risk of cardiovascular disease among people living with HIV : a systematic review and meta‐analysis
inferredcites →https://doi.org/10.1111/j.1538-7836.2011.04235.xopenalex-snapshot
EMMPRIN (CD147/basigin) mediates platelet–monocyte interactions in vivo and augments monocyte recruitment to the vascular wall
inferredcites →https://doi.org/10.1160/th08-03-0165openalex-snapshot
Transendothelial migration drives dissociation of plateletmonocyte complexes
inferredcites →https://doi.org/10.1161/01.atv.0000106320.40933.e5openalex-snapshot
Platelet-Monocyte Complexes Support Monocyte Adhesion to Endothelium by Enhancing Secondary Tethering and Cluster Formation
inferredcites →https://doi.org/10.1161/01.atv.20.12.2702openalex-snapshot
Platelet-Leukocyte Cross Talk in Whole Blood
inferredcites →https://doi.org/10.1161/01.cir.0000028962.04520.01openalex-snapshot
Platelet-Derived CD40L
inferredcites →https://doi.org/10.1161/atvbaha.111.243485openalex-snapshot
Contribution of Platelet CX 3 CR1 to Platelet–Monocyte Complex Formation and Vascular Recruitment During Hyperlipidemia
inferredcites →https://doi.org/10.1164/rccm.200702-214ocopenalex-snapshot
Allergen Induces the Migration of Platelets to Lung Tissue in Allergic Asthma
inferredcites →https://doi.org/10.1182/blood-2009-07-235028openalex-snapshot
Comparison of gene expression profiles between human and mouse monocyte subsets
inferredcites →https://doi.org/10.1182/blood-2011-10-384826openalex-snapshot
Cysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytes
inferredcites →https://doi.org/10.1182/blood.v60.4.834.834openalex-snapshot
Isolation of human platelet membrane microparticles from plasma and serum
inferredcites →https://doi.org/10.1182/blood.v78.7.1730.1730openalex-snapshot
Dynamics of leukocyte-platelet adhesion in whole blood
inferredcites →https://doi.org/10.1182/blood.v94.11.3791openalex-snapshot
Activated Platelets Release Two Types of Membrane Vesicles: Microvesicles by Surface Shedding and Exosomes Derived From Exocytosis of Multivesicular Bodies and -Granules
inferredcites →https://doi.org/10.1182/blood.v94.8.2725.420k18_2725_2734openalex-snapshot
Circulating Activated Platelets Assist THP-1 Monocytoid/Endothelial Cell Interaction Under Shear Stress
inferredcites →https://doi.org/10.1189/jlb.0307191openalex-snapshot
Monocyte subpopulations and their differentiation patterns during infection
inferredcites →https://doi.org/10.1189/jlb.0605318openalex-snapshot
Platelet binding to monocytes increases the adhesive properties of monocytes by up-regulating the expression and functionality of β1 and β2 integrins
inferredcites →https://doi.org/10.1189/jlb.0708400openalex-snapshot
Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseases
inferredcites →https://doi.org/10.1189/jlb.1012523openalex-snapshot
Attenuation of HIV-1 replication in macrophages by cannabinoid receptor 2 agonists
inferredcites →https://doi.org/10.1212/01.wnl.0000204294.28189.03openalex-snapshot
Valproic acid adjunctive therapy for HIV-associated cognitive impairment: A first report
inferredcites →https://doi.org/10.1212/wnl.0b013e318200d727openalex-snapshot
HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy
inferredcites →https://doi.org/10.1212/wnl.42.9.1736openalex-snapshot
Early viral brain invasion in iatrogenic human immunodeficiency virus infection
inferredcites →https://doi.org/10.1371/journal.pone.0051793openalex-snapshot
Excess Soluble CD40L Contributes to Blood Brain Barrier Permeability In Vivo: Implications for HIV-Associated Neurocognitive Disorders
inferredcites →https://doi.org/10.1371/journal.pone.0059950openalex-snapshot
Valproic Acid Inhibits the Release of Soluble CD40L Induced by Non-Nucleoside Reverse Transcriptase Inhibitors in Human Immunodeficiency Virus Infected Individuals
inferredcites →https://doi.org/10.1523/jneurosci.5796-09.2010openalex-snapshot
Dyad of CD40/CD40 Ligand Fosters Neuroinflammation at the Blood-Brain Barrier and Is Regulated via JNK Signaling: Implications for HIV-1 Encephalitis
inferredcites →https://doi.org/10.2174/157016208785861195openalex-snapshot
Cellular Reservoirs of HIV-1 and their Role in Viral Persistence
inferredcites →https://doi.org/10.4049/jimmunol.1001911openalex-snapshot
Antiplatelet Activity of Valproic Acid Contributes to Decreased Soluble CD40 Ligand Production in HIV Type 1-Infected Individuals
inferredcites →https://doi.org/10.4049/jimmunol.163.1.367openalex-snapshot
P-Selectin Binding Promotes the Adhesion of Monocytes to VCAM-1 Under Flow Conditions
inferredcites →https://doi.org/10.4049/jimmunol.178.10.6581openalex-snapshot
The CD16+ Monocyte Subset Is More Permissive to Infection and Preferentially Harbors HIV-1 In Vivo
inferredcites →https://doi.org/10.4049/jimmunol.178.5.3226openalex-snapshot
Functional Synergy between CD40 Ligand and HIV-1 Tat Contributes to Inflammation: Implications in HIV Type 1 Dementia
inferredcites →https://doi.org/10.4049/jimmunol.180.3.1854openalex-snapshot
Activation of Peroxisome Proliferator-Activated Receptor γ (PPARγ) Suppresses Rho GTPases in Human Brain Microvascular Endothelial Cells and Inhibits Adhesion and Transendothelial Migration of HIV-1 Infected Monocytes

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.5083913openalex-extracted
inferred← citeshttps://doi.org/10.1002/cyto.a.22683openalex-snapshot
Novel flow cytometric analysis of the blood–brain barrier
inferred← citeshttps://doi.org/10.1002/jlb.3a0620-460rropenalex-snapshot
Monocytes complexed to platelets differentiate into functionally deficient dendritic cells
inferred← citeshttps://doi.org/10.1002/jlb.4mr0620-701ropenalex-snapshot
Innate immune receptors in platelets and platelet-leukocyte interactions
inferred← citeshttps://doi.org/10.1002/jmv.29550openalex-snapshot
Longitudinal analysis of CSF HIV RNA in untreated people with HIV: Identification of CSF controllers
inferred← citeshttps://doi.org/10.1007/978-1-4939-3302-0_2openalex-snapshot
Principles of Amnis Imaging Flow Cytometry
inferred← citeshttps://doi.org/10.1007/978-3-319-47462-5_72openalex-snapshot
Virus–Platelet Associations
inferred← citeshttps://doi.org/10.1007/s11481-017-9761-6openalex-snapshot
Differential Effects of Antiretroviral Drugs on Neurons In Vitro: Roles for Oxidative Stress and Integrated Stress Response
inferred← citeshttps://doi.org/10.1007/s11481-018-9785-6openalex-snapshot
HIV and the Macrophage: From Cell Reservoirs to Drug Delivery to Viral Eradication
inferred← citeshttps://doi.org/10.1007/s13365-017-0582-4openalex-snapshot
An SIV/macaque model targeted to study HIV-associated neurocognitive disorders
inferred← citeshttps://doi.org/10.1007/s13365-026-01315-9openalex-snapshot
Clinical and behavioral predictors of HIV-associated neurocognitive disorder among people with HIV who use substances: a secondary analysis of the HOPE trial
inferred← citeshttps://doi.org/10.1016/j.jtha.2024.08.014openalex-snapshot
Viral coagulation: pushing the envelope
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2014.09.016openalex-snapshot
Neural effects of inflammation, cardiovascular disease, and HIV: Parallel, perpendicular, or progressive?
inferred← citeshttps://doi.org/10.1016/j.thromres.2018.07.003openalex-snapshot
The HIV protease inhibitor, ritonavir, dysregulates human platelet function in vitro
inferred← citeshttps://doi.org/10.1016/j.thromres.2021.05.010openalex-snapshot
Hypotheses behind the very rare cases of thrombosis with thrombocytopenia syndrome after SARS-CoV-2 vaccination
inferred← citeshttps://doi.org/10.1016/j.tube.2018.05.002openalex-snapshot
Platelet-monocyte interaction in Mycobacterium tuberculosis infection
inferred← citeshttps://doi.org/10.1038/s41575-021-00549-8openalex-snapshot
Liver ischaemia–reperfusion injury: a new understanding of the role of innate immunity
inferred← citeshttps://doi.org/10.1038/s41598-019-43275-7openalex-snapshot
Platelet function in HIV plus dengue coinfection associates with reduced inflammation and milder dengue illness
inferred← citeshttps://doi.org/10.1038/s41598-024-80372-8openalex-snapshot
Tensor-valued diffusion MRI detects brain microstructural abnormalities in HIV infected individuals with cognitive impairment
inferred← citeshttps://doi.org/10.1038/srep22508openalex-snapshot
Frog Virus 3 dissemination in the brain of tadpoles, but not in adult Xenopus, involves blood brain barrier dysfunction
inferred← citeshttps://doi.org/10.1038/srep26876openalex-snapshot
Smoothened Agonist Reduces Human Immunodeficiency Virus Type-1-Induced Blood-Brain Barrier Breakdown in Humanized Mice
inferred← citeshttps://doi.org/10.1055/s-0038-1673342openalex-snapshot
Monocytes of Different Subsets in Complexes with Platelets in Patients with Myocardial Infarction
inferred← citeshttps://doi.org/10.1055/s-0044-1791512openalex-snapshot
Modulating Immune Responses: The Double-Edged Sword of Platelet CD40L
inferred← citeshttps://doi.org/10.1080/09537104.2021.1952179openalex-snapshot
Platelet–leukocyte interactions in the pathogenesis of viral infections
inferred← citeshttps://doi.org/10.1080/1061186x.2022.2071426openalex-snapshot
Macrophage membrane biomimetic drug delivery system: for inflammation targeted therapy
inferred← citeshttps://doi.org/10.1089/aid.2017.0026openalex-snapshot
Refining Current Scientific Priorities and Identifying New Scientific Gaps in HIV-Related Heart, Lung, Blood, and Sleep Research
inferred← citeshttps://doi.org/10.1093/infdis/jiz051openalex-snapshot
CD8+ T-Cell–Derived Tumor Necrosis Factor Can Induce Tissue Factor Expression on Monocytes
inferred← citeshttps://doi.org/10.1093/jleuko/qiag116openalex-snapshot
Circulating platelet-natural killer cell complexes are elevated in people living with human immunodeficiency virus on antiretroviral therapy
inferred← citeshttps://doi.org/10.1093/ofid/ofw278openalex-snapshot
A Randomized Placebo Controlled Trial of Aspirin Effects on Immune Activation in Chronically Human Immunodeficiency Virus-Infected Adults on Virologically Suppressive Antiretroviral Therapy
inferred← citeshttps://doi.org/10.1097/id9.0000000000000013openalex-snapshot
Extinguish the Fire: Anti-inflammatory Strategies for Over Immune Activation in Chronic HIV-1 Infection
inferred← citeshttps://doi.org/10.1097/qad.0000000000000701openalex-snapshot
Activated platelet–T-cell conjugates in peripheral blood of patients with HIV infection
inferred← citeshttps://doi.org/10.1101/2022.11.09.515900openalex-snapshot
Analysis of clinical manifestations and risk factors of HIV-1 associated thrombocytopenia in a general teaching hospital in western China
inferred← citeshttps://doi.org/10.1101/2023.03.24.23287660openalex-snapshot
Role of non-classical monocytes in HIV-associated vascular cognitive impairment
inferred← citeshttps://doi.org/10.1111/eci.12871openalex-snapshot
Decision shaping neutrophil‐platelet interplay in inflammation: From physiology to intervention
inferred← citeshttps://doi.org/10.1111/jcmm.15037openalex-snapshot
Histamine deficiency facilitates coronary microthrombosis after myocardial infarction by increasing neutrophil‐platelet interactions
inferred← citeshttps://doi.org/10.1159/000444807openalex-snapshot
Platelet Interaction with Innate Immune Cells
inferred← citeshttps://doi.org/10.11606/t.17.2022.tde-03012023-105738openalex-snapshot
Avaliação dos aspectos clínicos, epidemiológicos e sorológicos da dengue em pacientes infectados pelo HIV: um estudo coorte prospectivo na cidade de Birigui, estado de São Paulo
inferred← citeshttps://doi.org/10.1161/hypertensionaha.116.08373openalex-snapshot
Renal Denervation Reduces Monocyte Activation and Monocyte–Platelet Aggregate Formation
inferred← citeshttps://doi.org/10.1161/jaha.125.046482openalex-snapshot
Monocytes Defined by Platelet Interactions and Oxidative Stress Signaling Underlie HIV‐Associated Atherosclerosis
inferred← citeshttps://doi.org/10.1172/jci.insight.122943openalex-snapshot
Platelet-derived β2M regulates monocyte inflammatory responses
inferred← citeshttps://doi.org/10.1182/bloodadvances.2020002420openalex-snapshot
Platelets function as an acute viral reservoir during HIV-1 infection by harboring virus and T-cell complex formation
inferred← citeshttps://doi.org/10.1186/s12865-015-0092-1openalex-snapshot
Human platelets and their capacity of binding viruses: meaning and challenges?
inferred← citeshttps://doi.org/10.1186/s12916-020-01801-9openalex-snapshot
Platelet activation in adult HIV-infected patients on antiretroviral therapy: a systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1186/s12967-025-06591-3openalex-snapshot
Over-activation and dysfunction of platelet-NK cell aggregates in HIV-infected individuals
inferred← citeshttps://doi.org/10.1371/journal.pone.0130061openalex-snapshot
Platelet Activation in Human Immunodeficiency Virus Type-1 Patients Is Not Altered with Cocaine Abuse
inferred← citeshttps://doi.org/10.15789/1563-0625-pli-2511openalex-snapshot
Platelet-leukocyte interactions: immunoregulatory role and pathophysiological relevance
inferred← citeshttps://doi.org/10.2147/idr.s517427openalex-snapshot
Analysis of Manifestations and Associated Factors of HIV-1 Associated Thrombocytopenia in a General Teaching Hospital in Western China
inferred← citeshttps://doi.org/10.2147/jir.s556871openalex-snapshot
P-Selectin and Platelet–Monocyte Interaction in Inflammation: Mechanisms, Hypothesis, and Open Questions
inferred← citeshttps://doi.org/10.3103/s0096392518030069openalex-snapshot
Role of Platelets in Neuroinflammatory Disorders. A Review
inferred← citeshttps://doi.org/10.3109/09537104.2015.1025376openalex-snapshot
Platelet interactions with viruses and parasites
inferred← citeshttps://doi.org/10.3389/fimmu.2015.00098openalex-snapshot
Platelets in Inflammation and Atherogenesis
inferred← citeshttps://doi.org/10.3389/fimmu.2018.01000openalex-snapshot
Platelets Promote Brucella abortus Monocyte Invasion by Establishing Complexes With Monocytes
inferred← citeshttps://doi.org/10.3389/fimmu.2021.634386openalex-snapshot
Interactions of HIV and Antiretroviral Therapy With Neutrophils and Platelets
inferred← citeshttps://doi.org/10.3389/fimmu.2021.649465openalex-snapshot
Platelets in HIV: A Guardian of Host Defence or Transient Reservoir of the Virus?
inferred← citeshttps://doi.org/10.3389/fimmu.2021.799124openalex-snapshot
Increased Platelet-CD4+ T Cell Aggregates Are Correlated With HIV-1 Permissiveness and CD4+ T Cell Loss
inferred← citeshttps://doi.org/10.3389/fimmu.2022.1033712openalex-snapshot
Circulating brain-derived extracellular vesicles expressing neuroinflammatory markers are associated with HIV-related neurocognitive impairment
inferred← citeshttps://doi.org/10.3389/fimmu.2022.879552openalex-snapshot
One Shoot, Two Birds: Alleviating Inflammation Caused by Ischemia/Reperfusion Injury to Reduce the Recurrence of Hepatocellular Carcinoma
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1165989openalex-snapshot
Effects of the interactions between platelets with other cells in tumor growth and progression
inferred← citeshttps://doi.org/10.3389/fimmu.2026.1938898openalex-snapshot
Inflammation identity crisis: pathogenic nature of platelet-derived transforming growth factor β in chronic inflammatory conditions
inferred← citeshttps://doi.org/10.3389/fmed.2018.00121openalex-snapshot
Platelets in Immune Response to Virus and Immunopathology of Viral Infections
inferred← citeshttps://doi.org/10.3389/fneur.2020.595463openalex-snapshot
Pathomechanisms of HIV-Associated Cerebral Small Vessel Disease: A Comprehensive Clinical and Neuroimaging Protocol and Analysis Pipeline
inferred← citeshttps://doi.org/10.3389/fped.2025.1560242openalex-snapshot
Platelet specific knockout of integrin beta-3 (β3) reduces severity of necrotizing enterocolitis in murine neonates
inferred← citeshttps://doi.org/10.3390/cells10081985openalex-snapshot
Contemporary Lifestyle and Neutrophil Extracellular Traps: An Emerging Link in Atherosclerosis Disease
inferred← citeshttps://doi.org/10.3390/ijms22157894openalex-snapshot
Platelet Innate Immune Receptors and TLRs: A Double-Edged Sword
inferred← citeshttps://doi.org/10.3390/ijms23042321openalex-snapshot
Platelet-Released Factors: Their Role in Viral Disease and Applications for Extracellular Vesicle (EV) Therapy
inferred← citeshttps://doi.org/10.3390/ijms23073868openalex-snapshot
Beyond Hemostasis: Platelet Innate Immune Interactions and Thromboinflammation
inferred← citeshttps://doi.org/10.3390/ijms25094697openalex-snapshot
HIV-Associated Neurocognitive Disorder: A Look into Cellular and Molecular Pathology
inferred← citeshttps://doi.org/10.3390/jcm10040877openalex-snapshot
Thrombocytopenia in Virus Infections
inferred← citeshttps://doi.org/10.3390/microorganisms11040958openalex-snapshot
Association of Antiretroviral Therapy with Platelet Function and Systemic Inflammatory Response in People Living with HIV: A Cross-Sectional Study
inferred← citeshttps://doi.org/10.3390/pathogens9090708openalex-snapshot
Brucella abortus-Stimulated Platelets Activate Brain Microvascular Endothelial Cells Increasing Cell Transmigration through the Erk1/2 Pathway
inferred← citeshttps://doi.org/10.5772/60747openalex-snapshot
Platelet Interactions with Viruses and Parasites
inferred← citeshttps://doi.org/10.6084/m9.figshare.13250660openalex-snapshot
Additional file 1 of Platelet activation in adult HIV-infected patients on antiretroviral therapy: a systematic review and meta-analysis
inferred← citeshttps://doi.org/10.70675/bf41a02ez6e11z4d57zb862z4383855ebed9openalex-snapshot
Rôle inflammatoire des plaquettes sanguines lors du sepsis
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