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Regulation of Alternative Macrophage Activation by Galectin-3

https://doi.org/10.4049/jimmunol.180.4.2650

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Galectin-3 in atrial fibrillation: Simple bystander, player or both?

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Systemic and hepatic vein galectin-3 are increased in patients with alcoholic liver cirrhosis and negatively correlate with liver function

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The intricate relationship between cytokines and galectins in immune modulation

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Galectin-3: mediator of microglia responses in injured brain

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Galectins and cutaneous immunity

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Immunoprotective neo-glycoproteins: Chemoenzymatic synthesis of multivalent glycomimetics for inhibition of cancer-related galectin-3

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Glycan recognition at the interface of the intestinal immune system: Target for immune modulation via dietary components

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Galectin-3 and post-myocardial infarction cardiac remodeling

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Galectin-3 mediates survival and apoptosis pathways during Trypanosoma cruzi–host cell interplay

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Re‐wiring regulatory cell networks in immunity by galectin–glycan interactions

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Galectin-3 protects auditory function in female mice

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Novel pathogenic role for galectin-3 in early disease stages of arrhythmogenic cardiomyopathy

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Profound connection between atherosclerosis and cancer: The role of galectin-3: A review

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Clinical significance of plasma galectin-3 in patients with coronary artery disease

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Galectin-3 in the fibrotic response: Cellular targets and molecular mechanisms

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Galectin-3 inhibits the chemotaxis of human polymorphonuclear neutrophils in vitro

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Soluble IgE receptors—Elements of the IgE network

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Regulatory Circuits Mediated by Lectin-Glycan Interactions in Autoimmunity and Cancer

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Endogenous lectins shape the function of dendritic cells and tailor adaptive immunity: Mechanisms and biomedical applications

inferred← citeshttps://doi.org/10.1016/j.intimp.2015.01.003openalex-snapshot

Enalapril treatment increases T cell number and promotes polarization towards M1-like macrophages locally in diabetic nephropathy

inferred← citeshttps://doi.org/10.1016/j.jacbts.2016.03.003openalex-snapshot

Galectin-3 Regulates Atrial Fibrillation Remodeling and Predicts Catheter Ablation Outcomes

inferred← citeshttps://doi.org/10.1016/j.jbc.2022.102622openalex-snapshot

Chimeric galectin-3 and collagens: Biomarkers and potential therapeutic targets in fibroproliferative diseases

inferred← citeshttps://doi.org/10.1016/j.jdermsci.2010.12.007openalex-snapshot

CD98hc (SLC3A2) is a key regulator of keratinocyte adhesion

inferred← citeshttps://doi.org/10.1016/j.jdermsci.2011.07.008openalex-snapshot

Galectin-3 and the skin

inferred← citeshttps://doi.org/10.1016/j.jff.2016.08.052openalex-snapshot

Extracts of Chilean native fruits inhibit oxidative stress, inflammation and insulin-resistance linked to the pathogenic interaction between adipocytes and macrophages

inferred← citeshttps://doi.org/10.1016/j.jid.2016.01.014openalex-snapshot

Genetic Deletion of Galectin-3 Does Not Impair Full-Thickness Excisional Skin Healing

inferred← citeshttps://doi.org/10.1016/j.jphs.2021.03.011openalex-snapshot

Pentoxifylline treatment alleviates kidney ischemia/reperfusion injury: Novel involvement of galectin-3 and ASK-1/JNK & ERK1/2/NF-κB/HMGB-1 trajectories

inferred← citeshttps://doi.org/10.1016/j.jprot.2011.06.012openalex-snapshot

Identification of Brugia malayi immunogens by an immunoproteomics approach

inferred← citeshttps://doi.org/10.1016/j.kint.2019.01.029openalex-snapshot

Interaction between galectin-3 and cystinosin uncovers a pathogenic role of inflammation in kidney involvement of cystinosis

inferred← citeshttps://doi.org/10.1016/j.mam.2018.07.001openalex-snapshot

Cardiac fibrosis: Cell biological mechanisms, molecular pathways and therapeutic opportunities

inferred← citeshttps://doi.org/10.1016/j.matbio.2015.03.003openalex-snapshot

Inflammatory microenvironment and tumor necrosis factor alpha as modulators of periostin and CCN2 expression in human non-healing skin wounds and dermal fibroblasts

inferred← citeshttps://doi.org/10.1016/j.metabol.2018.02.001openalex-snapshot

Galectin-3 is essential for proper bone cell differentiation and activity, bone remodeling and biomechanical competence in mice

inferred← citeshttps://doi.org/10.1016/j.metabol.2020.154137openalex-snapshot

Time for a paradigm shift in treating type 1 diabetes mellitus: coupling inflammation to islet regeneration

inferred← citeshttps://doi.org/10.1016/j.mex.2020.100935openalex-snapshot

A novel immunofluorescence detection method for renal cell-type specific in situ cytokine production by confocal microscopy

inferred← citeshttps://doi.org/10.1016/j.molbiopara.2010.06.013openalex-snapshot

Identification of Dirofilaria immitis immunoreactive proteins recognized by sera from infected cats using two-dimensional electrophoresis and mass spectrometry

inferred← citeshttps://doi.org/10.1016/j.molimm.2009.07.026openalex-snapshot

Regulation of expression and secretion of galectin-3 in human monocyte-derived dendritic cells

inferred← citeshttps://doi.org/10.1016/j.nbd.2013.11.009openalex-snapshot

Spinal but not cortical microglia acquire an atypical phenotype with high VEGF, galectin-3 and osteopontin, and blunted inflammatory responses in ALS rats

inferred← citeshttps://doi.org/10.1016/j.neuroscience.2014.09.027openalex-snapshot

The neuroimmunology of degeneration and regeneration in the peripheral nervous system

inferred← citeshttps://doi.org/10.1016/j.neuroscience.2018.02.048openalex-snapshot

Brain Response to Injuries: When Microglia Go Sexist

inferred← citeshttps://doi.org/10.1016/j.neuroscience.2018.05.047openalex-snapshot

Interleukin-33 Protects Ischemic Brain Injury by Regulating Specific Microglial Activities

inferred← citeshttps://doi.org/10.1016/j.pharmthera.2026.109125openalex-snapshot

Galectin-3 and its inhibitors: Overview and perspectives

inferred← citeshttps://doi.org/10.1016/j.phrs.2019.104285openalex-snapshot

Emerging role of glycosylation in the polarization of tumor-associated macrophages

inferred← citeshttps://doi.org/10.1016/j.reth.2022.06.009openalex-snapshot

Mesenchymal stem cells pretreated with proinflammatory cytokines accelerate skin wound healing by promoting macrophages migration and M2 polarization

inferred← citeshttps://doi.org/10.1016/j.semnephrol.2010.03.004openalex-snapshot

Macrophages and Renal Fibrosis

inferred← citeshttps://doi.org/10.1016/j.smim.2024.101926openalex-snapshot

Decoding the multifaceted roles of galectins in self-defense

inferred← citeshttps://doi.org/10.1016/j.taap.2012.06.009openalex-snapshot

Classical and alternative macrophage activation in the lung following ozone-induced oxidative stress

inferred← citeshttps://doi.org/10.1016/j.tcm.2009.10.001openalex-snapshot

Galectins in Atherosclerotic Disease

inferred← citeshttps://doi.org/10.1016/j.tibs.2016.11.003openalex-snapshot

Translating the ‘Sugar Code’ into Immune and Vascular Signaling Programs

inferred← citeshttps://doi.org/10.1016/j.vph.2016.02.006openalex-snapshot

The emerging role of galectins in cardiovascular disease

inferred← citeshttps://doi.org/10.1016/j.waojou.2024.100955openalex-snapshot

Serum Galectin-10: A biomarker for persistent airflow limitation in adult asthmatics

inferred← citeshttps://doi.org/10.1016/j.yexcr.2015.07.010openalex-snapshot

CD99 inhibits CD98-mediated β1 integrin signaling through SHP2-mediated FAK dephosphorylation

inferred← citeshttps://doi.org/10.1016/j.yexcr.2017.03.059openalex-snapshot

The association between oxidative stress-induced galectins and differentiation of human promyelocytic HL-60 cells

inferred← citeshttps://doi.org/10.1016/j.yexcr.2018.03.009openalex-snapshot

Complement 5a stimulates macrophage polarization and contributes to tumor metastases of colon cancer

inferred← citeshttps://doi.org/10.1016/j.yexmp.2014.05.009openalex-snapshot

Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammation

inferred← citeshttps://doi.org/10.1016/j.yexmp.2016.07.005openalex-snapshot

M1-/M2-macrophage polarization in pseudolobules consisting of adipohilin-rich hepatocytes in thioacetamide (TAA)-induced rat hepatic cirrhosis

inferred← citeshttps://doi.org/10.1021/acs.biomac.0c00515openalex-snapshot

Glycopolymers for Efficient Inhibition of Galectin-3: In Vitro Proof of Efficacy Using Suppression of T Lymphocyte Apoptosis and Tumor Cell Migration

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.2c00660openalex-snapshot

Discovery and Optimization of the First Highly Effective and Orally Available Galectin-3 Inhibitors for Treatment of Fibrotic Disease

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5c02604openalex-snapshot

N -Aryl- N -Lactosylamides as Potent and Highly Selective Inhibitors of Galectin-3 with Antifibrotic Activity

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.6b00957openalex-snapshot

A Selective Galactose–Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.6c00330openalex-snapshot

A Structural Perspective on Non-covalent Targeting of Conserved Polar Residues in Protein Kinases

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.7b01626openalex-snapshot

Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity

inferred← citeshttps://doi.org/10.1021/bi201459popenalex-snapshot

The Carbohydrate-Binding Site in Galectin-3 Is Preorganized To Recognize a Sugarlike Framework of Oxygens: Ultra-High-Resolution Structures and Water Dynamics

inferred← citeshttps://doi.org/10.1021/bk-2012-1115.ch002openalex-snapshot

Low-Molecular Weight Inhibitors of Galectins

inferred← citeshttps://doi.org/10.1021/bk-2012-1115.ch012openalex-snapshot

Galectin-3C: Human Lectin for Treatment of Cancer

inferred← citeshttps://doi.org/10.1021/bk-2012-1115.ch014openalex-snapshot

Galectins and Pathologies: Role of Galectin-3 in the Communication between Leukemia Cells and the Microenvironment

inferred← citeshttps://doi.org/10.1021/bk-2012-1115.ch019openalex-snapshot

A Therapeutic Role for Galectins in Acute Inflammation?

inferred← citeshttps://doi.org/10.1021/bk-2012-1115.ch021openalex-snapshot

Autoimmune Disorders in Galectin-3 Deficient Mice

inferred← citeshttps://doi.org/10.1021/bk-2012-1115.ch022openalex-snapshot

Galectin-3: A Central Regulator of Chronic Inflammation and Tissue Fibrosis

inferred← citeshttps://doi.org/10.1038/cdd.2016.132openalex-snapshot

Modulation of macrophage antitumor potential by apoptotic lymphoma cells

inferred← citeshttps://doi.org/10.1038/jid.2012.211openalex-snapshot

Galectin-3 Regulates Intracellular Trafficking of EGFR through Alix and Promotes Keratinocyte Migration

inferred← citeshttps://doi.org/10.1038/labinvest.2015.77openalex-snapshot

Galectin 3 regulates HCC cell invasion by RhoA and MLCK activation

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