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Plasma total homocysteine is associated with DNA methylation in patients with schizophrenia

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/archpsyc.60.6.618openalex-snapshot
Folate, Vitamin B12, Homocysteine, and the MTHFR 677C→T Polymorphism in Anxiety and Depression
inferredcites →https://doi.org/10.1001/archpsyc.64.1.31openalex-snapshot
Elevated Prenatal Homocysteine Levels as a Risk Factor for Schizophrenia
inferredcites →https://doi.org/10.1001/archpsyc.65.11.1286openalex-snapshot
Homocysteine and Depression in Later Life
inferredcites →https://doi.org/10.1002/ajmg.b.30499openalex-snapshot
Identification of two risk haplotypes for schizophrenia and bipolar disorder in the synaptic vesicle monoamine transporter gene (SVMT)
inferredcites →https://doi.org/10.1002/ajmg.b.31192openalex-snapshot
Hypomethylation of the serotonin receptor type‐2A Gene (HTR2A) at T102C polymorphic site in DNA derived from the saliva of patients with schizophrenia and bipolar disorder
inferredcites →https://doi.org/10.1002/jbt.20298openalex-snapshot
Effects of S‐adenosylhomocysteine and homocysteine on DNA damage and cell cytotoxicity in murine hepatic and microglia cell lines
inferredcites →https://doi.org/10.1002/jcb.20578openalex-snapshot
Mitochondrial mechanism of oxidative stress and systemic hypertension in hyperhomocysteinemia
inferredcites →https://doi.org/10.1007/s00439-011-1131-5openalex-snapshot
Effects of MAOA promoter methylation on susceptibility to paranoid schizophrenia
inferredcites →https://doi.org/10.1007/s00702-004-0232-xopenalex-snapshot
Homocysteine associated genomic DNA hypermethylation in patients with chronic alcoholism
inferredcites →https://doi.org/10.1007/s11010-011-0836-zopenalex-snapshot
Methylation of the promoter A of estrogen receptor alpha gene in hBMSC and osteoblasts and its correlation with homocysteine
inferredcites →https://doi.org/10.1007/s11064-012-0707-3openalex-snapshot
The Oxidative Stress May be Induced by the Elevated Homocysteine in Schizophrenic Patients
inferredcites →https://doi.org/10.1007/s12017-012-8198-6openalex-snapshot
DNA Methylation Signatures of Peripheral Leukocytes in Schizophrenia
inferredcites →https://doi.org/10.1016/j.ajhg.2008.01.008openalex-snapshot
Epigenomic Profiling Reveals DNA-Methylation Changes Associated with Major Psychosis
inferredcites →https://doi.org/10.1016/j.ajhg.2009.02.011openalex-snapshot
Genome-wide Association Study of Vitamin B6, Vitamin B12, Folate, and Homocysteine Blood Concentrations
inferredcites →https://doi.org/10.1016/j.ajhg.2011.12.020openalex-snapshot
DNA Methylation Signatures in Development and Aging of the Human Prefrontal Cortex
inferredcites →https://doi.org/10.1016/j.biopsych.2004.11.022openalex-snapshot
A family-based association study and gene expression analyses of netrin-G1 and -G2 genes in schizophrenia
inferredcites →https://doi.org/10.1016/j.biopsych.2004.11.046openalex-snapshot
Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice
inferredcites →https://doi.org/10.1016/j.biopsych.2007.07.003openalex-snapshot
Methylation Status of the Reelin Promoter Region in the Brain of Schizophrenic Patients
inferredcites →https://doi.org/10.1016/j.biopsych.2009.12.004openalex-snapshot
Markers of Glutamate Synaptic Transmission and Plasticity Are Increased in the Anterior Cingulate Cortex in Bipolar Disorder
inferredcites →https://doi.org/10.1016/j.jad.2011.03.018openalex-snapshot
Increased DNA methylation status of the serotonin receptor 5HTR1A gene promoter in schizophrenia and bipolar disorder
inferredcites →https://doi.org/10.1016/j.jalz.2010.08.234openalex-snapshot
Serum homocysteine and dementia: Meta‐analysis of eight cohort studies including 8669 participants
inferredcites →https://doi.org/10.1016/j.jpsychires.2006.08.006openalex-snapshot
Global hypomethylation of peripheral leukocyte DNA in male patients with schizophrenia: A potential link between epigenetics and schizophrenia
inferredcites →https://doi.org/10.1016/j.jpsychires.2011.06.013openalex-snapshot
DNA hypomethylation of MB-COMT promoter in the DNA derived from saliva in schizophrenia and bipolar disorder
inferredcites →https://doi.org/10.1016/j.molmed.2009.10.001openalex-snapshot
One-carbon metabolism and schizophrenia: current challenges and future directions
inferredcites →https://doi.org/10.1016/j.pathophys.2009.02.010openalex-snapshot
Hypermethylation of estrogen receptor-α gene in atheromatosis patients and its correlation with homocysteine
inferredcites →https://doi.org/10.1016/j.psychres.2010.04.008openalex-snapshot
Plasma homocysteine in schizophrenia: Determinants and clinical correlations in Tunisian patients free from antipsychotics
inferredcites →https://doi.org/10.1016/j.schres.2008.01.009openalex-snapshot
No association between global leukocyte DNA methylation and homocysteine levels in schizophrenia patients
inferredcites →https://doi.org/10.1016/j.schres.2011.04.007openalex-snapshot
Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder
inferredcites →https://doi.org/10.1016/j.ygeno.2011.07.007openalex-snapshot
High density DNA methylation array with single CpG site resolution
inferredcites →https://doi.org/10.1016/s0140-6736(03)13372-7openalex-snapshot
Folate treatment and unbalanced methylation and changes of allelic expression induced by hyperhomocysteinaemia in patients with uraemia
inferredcites →https://doi.org/10.1016/s0893-133x(00)00165-2openalex-snapshot
In Vivo Measurement of the Vesicular Monoamine Transporter in Schizophrenia
inferredcites →https://doi.org/10.1038/jhg.2012.140openalex-snapshot
Comprehensive DNA methylation analysis of peripheral blood cells derived from patients with first-episode schizophrenia
inferredcites →https://doi.org/10.1038/mp.2010.47openalex-snapshot
Imprinting in the schizophrenia candidate gene GABRB2 encoding GABAA receptor β2 subunit
inferredcites →https://doi.org/10.1038/nm.1962openalex-snapshot
A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia
inferredcites →https://doi.org/10.1038/sj.mp.4001713openalex-snapshot
Alternative transcripts and evidence of imprinting of GNAL on 18p11.2
inferredcites →https://doi.org/10.1038/sj.mp.4001746openalex-snapshot
Homocysteine, methylenetetrahydrofolate reductase and risk of schizophrenia: a meta-analysis
inferredcites →https://doi.org/10.1038/sj.npp.1301457openalex-snapshot
Decreased mRNA Expression of Netrin-G1 and Netrin-G2 in the Temporal Lobe in Schizophrenia and Bipolar Disorder
inferredcites →https://doi.org/10.1073/pnas.0503736102openalex-snapshot
Reelin promoter hypermethylation in schizophrenia
inferredcites →https://doi.org/10.1086/302046openalex-snapshot
Support for a Chromosome 18p Locus Conferring Susceptibility to Functional Psychoses in Families with Schizophrenia, by Association and Linkage Analysis
inferredcites →https://doi.org/10.1093/hmg/ddi100openalex-snapshot
The impact of metabolism on DNA methylation
inferredcites →https://doi.org/10.1093/hmg/ddl253openalex-snapshot
Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder
inferredcites →https://doi.org/10.1093/hmg/ddm347openalex-snapshot
A network of dopaminergic gene variations implicated as risk factors for schizophrenia
inferredcites →https://doi.org/10.1093/hmg/ddp428openalex-snapshot
Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway
inferredcites →https://doi.org/10.1093/hmg/ddp445openalex-snapshot
Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns
inferredcites →https://doi.org/10.1093/hmg/ddr416openalex-snapshot
Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder
inferredcites →https://doi.org/10.1093/oxfordjournals.schbul.a006988openalex-snapshot
Monozygotic Twins Exhibit Numerous Epigenetic Differences: Clues to Twin Discordance?
inferredcites →https://doi.org/10.1093/schbul/sbs067openalex-snapshot
Intermediate Phenotype Analysis of Patients, Unaffected Siblings, and Healthy Controls Identifies VMAT2 as a Candidate Gene for Psychotic Disorder and Neurocognition
inferredcites →https://doi.org/10.1096/fj.11-202069openalex-snapshot
Epigenetic aberrations in leukocytes of patients with schizophrenia: association of global DNA methylation with antipsychotic drug treatment and disease onset
inferredcites →https://doi.org/10.1161/circgenetics.108.829804openalex-snapshot
Novel Associations of CPS1, MUT, NOX4, and DPEP1 With Plasma Homocysteine in a Healthy Population
inferredcites →https://doi.org/10.1186/1471-2350-11-114openalex-snapshot
FOXP2 gene and language impairment in schizophrenia: association and epigenetic studies
inferredcites →https://doi.org/10.1186/1471-2350-7-10openalex-snapshot
The quantification of COMT mRNA in post mortem cerebellum tissue: diagnosis, genotype, methylation and expression
inferredcites →https://doi.org/10.1186/1744-9081-2-37openalex-snapshot
Haloperidol treatment induces tissue- and sex-specific changes in DNA methylation: a control study using rats
inferredcites →https://doi.org/10.1371/journal.pmed.0020141openalex-snapshot
A Systematic Review of the Prevalence of Schizophrenia
inferredcites →https://doi.org/10.1371/journal.pone.0000895openalex-snapshot
DNA Methylation in the Human Cerebral Cortex Is Dynamically Regulated throughout the Life Span and Involves Differentiated Neurons
inferredcites →https://doi.org/10.1523/jneurosci.0766-05.2005openalex-snapshot
DNA Methylation Status ofSOX10Correlates with Its Downregulation and Oligodendrocyte Dysfunction in Schizophrenia
inferredcites →https://doi.org/10.1523/jneurosci.20-18-06920.2000openalex-snapshot
Homocysteine Elicits a DNA Damage Response in Neurons That Promotes Apoptosis and Hypersensitivity to Excitotoxicity
inferredcites →https://doi.org/10.2217/epi.11.105openalex-snapshot
Evaluation of the Infinium Methylation 450K technology
inferredcites →https://doi.org/10.3109/15622975.2011.604350openalex-snapshot
TheKCNH2gene is associated with neurocognition and the risk of schizophrenia
inferredcites →https://doi.org/10.4161/epi.6.1.13392openalex-snapshot
Quantitative, high-resolution epigenetic profiling of CpG loci identifies associations with cord blood plasma homocysteine and birth weight in humans
inferredcites →https://doi.org/10.4161/epi.6.6.16196openalex-snapshot
Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Homocysteine Levels in Neurological Disorders
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Homocysteine facilitates endoplasmic reticulum stress and apoptosis of hepatocytes by suppressing ERO1α expression via cooperation between DNMT1 and G9a
inferred← citeshttps://doi.org/10.1002/jcb.29010openalex-snapshot
Impact of DNA methyltransferase inhibitor 5‐azacytidine on cardiac development of zebrafish in vivo and cardiomyocyte proliferation, apoptosis, and the homeostasis of gene expression in vitro
inferred← citeshttps://doi.org/10.1007/s11434-014-0690-yopenalex-snapshot
DNA methylation in schizophrenia: progress and challenges
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Epigenetics of Schizophrenia
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Approaches to Detecting DNA Base Modification in the Brain
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Pharmacoepigenetics of Antipsychotic Drugs
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Chronic mild hyperhomocysteinemia induces anxiety-like symptoms, aversive memory deficits and hippocampus atrophy in adult rats: New insights into physiopathological mechanisms
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Homocysteine as a peripheral biomarker in bipolar disorder: A meta-analysis
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Catechol-O-methyltransferase gene promoter methylation as a peripheral biomarker in male schizophrenia
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e30193openalex-snapshot
Associations among plasma markers for N-methyl-d-aspartate receptor hypofunction, redox dysregulation, and insufficient myelination in patients with schizophrenia
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Analytical methods involving separation techniques for determination of low-molecular-weight biothiols in human plasma and blood
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The effect of folate and VitB12 in the treatment of MCI patients with hyperhomocysteinemia
inferred← citeshttps://doi.org/10.1016/j.jpsychires.2021.03.010openalex-snapshot
Comparison of inflammatory, nutrient, and neurohormonal indicators in patients with schizophrenia, bipolar disorder and major depressive disorder
inferred← citeshttps://doi.org/10.1016/j.lfs.2022.121084openalex-snapshot
High-protein nutrition during pregnancy increases neuroinflammation and homocysteine levels and impairs behavior in male adolescent rats offspring
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A systematic review of the effect of genes mediating neurodevelopment and neurotransmission on brain morphology: Focus on schizophrenia
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Evaluation of hyperhomocysteinemia prevalence and its influence on the selected cognitive functions in patients with schizophrenia
inferred← citeshttps://doi.org/10.1016/j.psychres.2016.10.017openalex-snapshot
Cumulative effect of the plasma total homocysteine-related genetic variants on schizophrenia risk
inferred← citeshttps://doi.org/10.1016/j.psychres.2021.114218openalex-snapshot
Epigenetics of Schizophrenia
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Homocysteine-lowering gene therapy rescues signaling pathways in brain of mice with intermediate hyperhomocysteinemia
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Homocysteine inhibits endothelial progenitor cells proliferation via DNMT1-mediated hypomethylation of Cyclin A
inferred← citeshttps://doi.org/10.1016/j.ymgme.2014.07.016openalex-snapshot
Hyperhomocysteinemia: Related genetic diseases and congenital defects, abnormal DNA methylation and newborn screening issues
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Homocysteine and DNA methylation: A review of animal and human literature
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Homocysteine levels in schizophrenia patients newly admitted to an acute psychiatric ward
inferred← citeshttps://doi.org/10.1038/s41380-019-0601-3openalex-snapshot
Epigenetic mechanisms in schizophrenia and other psychotic disorders: a systematic review of empirical human findings
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Higher peripheral blood homocysteine levels are associated with schizophrenia: evidence from a case-control study and a meta-analysis
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Can the biological mechanisms of ageing be corrected by food supplementation. The concept of health care over sick care
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Assisted reproductive technology (ART) and epigenetic modifications in the placenta
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Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia, part III: Molecular mechanisms
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Meta-analyses of Blood Homocysteine Levels for Gender and Genetic Association Studies of the MTHFR C677T Polymorphism in Schizophrenia
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Biomarkers for Psychosis: Are We There Yet? Umbrella Review of 1478 Biomarkers
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Genome-wide analysis of DNA methylation and its relationship with serum homocysteine levels in patients with hypertension
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Canonical Correlation Analysis of Imaging Genetics Data Based on Statistical Independence and Structural Sparsity
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Specific molecular signatures of non‐tumor liver tissue may predict a risk of hepatocarcinogenesis
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Orthognathic surgery induces genomewide changes longitudinally in DNA methylation in saliva
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De novo mutations identified by whole-genome sequencing implicate chromatin modifications in obsessive-compulsive disorder
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Differential regulation of DNA methylation versus histone acetylation in cardiomyocytes during HHcy in vitro and in vivo: an epigenetic mechanism
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Homocysteine and Psychiatric Disorders
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Circulating levels of homocysteine, folate, and vitamin B12 in adults with and without schizophrenia: A systematic review and meta-analysis
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DNA methylation in peripheral tissue of schizophrenia and bipolar disorder: a systematic review
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Deciphering the shared genetic architecture between schizophrenia and suicide attempt: a statistical genomic study
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High-sensitive C-reactive protein and homocysteine levels in patients with newly diagnosed bipolar disorder, their first-degree relatives, and healthy control persons—Results from a clinical study
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Domain Specific Changes in Cognition at High Altitude and Its Correlation with Hyperhomocysteinemia
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Central and Systemic Responses to Methionine-Induced Hyperhomocysteinemia in Mice
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Cognitive Changes during Prolonged Stay at High Altitude and Its Correlation with C-Reactive Protein
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Epigenetic modifications associated with aortic remodeling in hyperhomocysteinemia.
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Characteristics of TCM Constitution and Related Biomarkers for Mild Cognitive Impairment
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Effect of epigenetic modulation on cancer sphere
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Folic Acid and Vitamin B12 Supplementation on Male Patients with Schizophrenia Predominant Negative Symptoms
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Understanding epigenetics of schizophrenia in the backdrop of its antipsychotic drug therapy
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Lower LINE-1 Methylation in First-Episode Schizophrenia Patients with the History of Childhood Trauma
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Relationship between homocysteine and cognitive impairment in elderly patients with chronic kidney disease
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Decreased whole-blood global DNA methylation is related to serum hormones in anorexia nervosa adolescents
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DNA Methylation and Gene Expression of Matrix Metalloproteinase 9 Gene in Deficit and Non-deficit Schizophrenia
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Homocysteine levels in schizophrenia and affective disorders—focus on cognition
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Vitamin B12 Levels in Methamphetamine Addicts
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DNMT gene expression in peripheral leukocytes in schizophrenia and correlations with one-carbon metabolites: folate, total homocysteine, and vitamin B6
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Involvements of Hyperhomocysteinemia in Neurological Disorders
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Investigation of Adverse Cancer Related DNA Methylation Variation in the Human Telomerase Reverse Transcriptase (hTERT) Promotor in Follicular Fluid Cells of Women Subjected to Ovarian Stimulation for In Vitro Fertilization (IVF)
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La signalisation insuline comme garant de la fonction barrière intestinale
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