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Intestinal Permeability Regulation by Tight Junction: Implication on Inflammatory Bowel Diseases

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/bf02064182openalex-snapshot
Elevation of interleukin-6 in inflammatory bowel disease is macrophage- and epithelial cell-dependent
inferredcites →https://doi.org/10.1007/bf02100148openalex-snapshot
Multiple sclerosis patients have peripheral blood CD45RO+ B cells and increased intestinal permeability
inferredcites →https://doi.org/10.1007/s00125-006-0465-3openalex-snapshot
Increased intestinal permeability precedes clinical onset of type 1 diabetes
inferredcites →https://doi.org/10.1007/s00384-003-0554-4openalex-snapshot
Cytokine/chemokine transcript profiles reflect mucosal inflammation in Crohn?s disease
inferredcites →https://doi.org/10.1007/s00441-009-0751-8openalex-snapshot
TNFα up-regulates claudin-2 expression in epithelial HT-29/B6 cells via phosphatidylinositol-3-kinase signaling
inferredcites →https://doi.org/10.1016/j.febslet.2006.03.048openalex-snapshot
Casein kinase Iε associates with and phosphorylates the tight junction protein occludin
inferredcites →https://doi.org/10.1016/j.yexcr.2003.12.014openalex-snapshot
Thr203 of claudin-1, a putative phosphorylation site for MAP kinase, is required to promote the barrier function of tight junctions
inferredcites →https://doi.org/10.1016/s0002-9270(02)04271-5openalex-snapshot
Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's disease
inferredcites →https://doi.org/10.1016/s0002-9440(10)61243-6openalex-snapshot
Transforming Growth Factor-β Regulation of Epithelial Tight Junction Proteins Enhances Barrier Function and Blocks Enterohemorrhagic Escherichia coli O157:H7-Induced Increased Permeability
inferredcites →https://doi.org/10.1016/s0002-9440(10)62264-xopenalex-snapshot
Interferon-γ and Tumor Necrosis Factor-α Synergize to Induce Intestinal Epithelial Barrier Dysfunction by Up-Regulating Myosin Light Chain Kinase Expression
inferredcites →https://doi.org/10.1016/s0016-5085(00)70351-9openalex-snapshot
Claudins regulate the intestinal barrier in response to immune mediators
inferredcites →https://doi.org/10.1016/s0016-5085(99)70551-2openalex-snapshot
Epithelial permeability to proteins in the noninflamed ileum of Crohn's disease?
inferredcites →https://doi.org/10.1016/s0079-6107(02)00037-8openalex-snapshot
Tight junction proteins
inferredcites →https://doi.org/10.1016/s0955-0674(03)00104-2openalex-snapshot
The JAM family of junctional adhesion molecules
inferredcites →https://doi.org/10.1038/35067088openalex-snapshot
Multifunctional strands in tight junctions
inferredcites →https://doi.org/10.1038/labinvest.3700373openalex-snapshot
Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease
inferredcites →https://doi.org/10.1038/nri2653openalex-snapshot
Intestinal mucosal barrier function in health and disease
inferredcites →https://doi.org/10.1042/bj20050959openalex-snapshot
MAPK interacts with occludin and mediates EGF-induced prevention of tight junction disruption by hydrogen peroxide
inferredcites →https://doi.org/10.1042/bj20110587openalex-snapshot
Protein kinase Cζ phosphorylates occludin and promotes assembly of epithelial tight junctions
inferredcites →https://doi.org/10.1046/j.1365-2249.1998.00481.xopenalex-snapshot
IL-4, IL-10 and IL-13 down-regulate monocyte-chemoattracting protein-1 (MCP-1) production in activated intestinal epithelial cells
inferredcites →https://doi.org/10.1046/j.1440-1746.2003.03032.xopenalex-snapshot
Intestinal barrier: An interface between health and disease
inferredcites →https://doi.org/10.1053/gast.2001.27060openalex-snapshot
Rho kinase regulates tight junction function and is necessary for tight junction assembly in polarized intestinal epithelia
inferredcites →https://doi.org/10.1053/j.gastro.2008.04.002openalex-snapshot
Unique Role of Junctional Adhesion Molecule-A in Maintaining Mucosal Homeostasis in Inflammatory Bowel Disease
inferredcites →https://doi.org/10.1053/j.gastro.2010.08.006openalex-snapshot
Loss of Claudin-15, but Not Claudin-2, Causes Na+ Deficiency and Glucose Malabsorption in Mouse Small Intestine
inferredcites →https://doi.org/10.1073/pnas.90.16.7834openalex-snapshot
The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions.
inferredcites →https://doi.org/10.1074/jbc.m002718200openalex-snapshot
A Novel Protein with Homology to the Junctional Adhesion Molecule
inferredcites →https://doi.org/10.1074/jbc.m111.238147openalex-snapshot
Interleukin-6 (IL-6) Regulates Claudin-2 Expression and Tight Junction Permeability in Intestinal Epithelium
inferredcites →https://doi.org/10.1074/jbc.m406563200openalex-snapshot
Establishment and Characterization of Cultured Epithelial Cells Lacking Expression of ZO-1
inferredcites →https://doi.org/10.1074/jbc.m602164200openalex-snapshot
Tumor Necrosis Factor-induced Long Myosin Light Chain Kinase Transcription Is Regulated by Differentiation-dependent Signaling Events
inferredcites →https://doi.org/10.1074/jbc.m804783200openalex-snapshot
Phosphorylation of Tyr-398 and Tyr-402 in Occludin Prevents Its Interaction with ZO-1 and Destabilizes Its Assembly at the Tight Junctions
inferredcites →https://doi.org/10.1083/jcb.123.6.1777openalex-snapshot
Occludin: a novel integral membrane protein localizing at tight junctions.
inferredcites →https://doi.org/10.1083/jcb.127.6.1617openalex-snapshot
Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions.
inferredcites →https://doi.org/10.1083/jcb.137.6.1393openalex-snapshot
Possible Involvement of Phosphorylation of Occludin in Tight Junction Formation
inferredcites →https://doi.org/10.1083/jcb.141.1.199openalex-snapshot
ZO-3, a Novel Member of the MAGUK Protein Family Found at the Tight Junction, Interacts with ZO-1 and Occludin
inferredcites →https://doi.org/10.1083/jcb.141.7.1539openalex-snapshot
Claudin-1 and -2: Novel Integral Membrane Proteins Localizing at Tight Junctions with No Sequence Similarity to Occludin
inferredcites →https://doi.org/10.1083/jcb.142.1.117openalex-snapshot
Junctional Adhesion Molecule, a Novel Member of the Immunoglobulin Superfamily That Distributes at Intercellular Junctions and Modulates Monocyte Transmigration
inferredcites →https://doi.org/10.1083/jcb.149.1.13openalex-snapshot
Pores in the Wall
inferredcites →https://doi.org/10.1083/jcb.200510043openalex-snapshot
Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells
inferredcites →https://doi.org/10.1084/jem.20071416openalex-snapshot
JAM-A regulates permeability and inflammation in the intestine in vivo
inferredcites →https://doi.org/10.1093/rheumatology/33.7.644openalex-snapshot
INTESTINAL PERMEABILITY IN PATIENTS WITH ANKYLOSING SPONDYLITIS AND THEIR HEALTHY RELATIVES
inferredcites →https://doi.org/10.1096/fasebj.8.15.8001745openalex-snapshot
The interleukin‐1 family: 10 years of discovery 1
inferredcites →https://doi.org/10.1096/fj.02-0121fjeopenalex-snapshot
Isolation and functional characterization of the actin‐binding region in the tight junction protein ZO‐1
inferredcites →https://doi.org/10.1096/fj.04-3260comopenalex-snapshot
Interferon‐γ induces internalization of epithelial tight junction proteins via a macropinocytosis‐like process
inferredcites →https://doi.org/10.1097/00042737-199710000-00004openalex-snapshot
A high serum concentration of interleukin-6 is predictive of relapse in quiescent Crohn??s disease
inferredcites →https://doi.org/10.1097/00054725-199911000-00004openalex-snapshot
Interleukin-10 Gene-Deficient Mice Develop a Primary Intestinal Permeability Defect in Response to Enteric Microflora
inferredcites →https://doi.org/10.1111/j.1365-2249.2007.03441.xopenalex-snapshot
The expanding family of interleukin-1 cytokines and their role in destructive inflammatory disorders
inferredcites →https://doi.org/10.1111/j.1365-2567.2011.03465.xopenalex-snapshot
The interleukin-17 cytokine family: critical players in host defence and inflammatory diseases
inferredcites →https://doi.org/10.1111/j.1572-0241.2006.00672.xopenalex-snapshot
Abnormal Intestinal Permeability in Subgroups of Diarrhea-Predominant Irritable Bowel Syndromes
inferredcites →https://doi.org/10.1111/j.1749-6632.2009.04054.xopenalex-snapshot
Occludin Phosphorylation in Regulation of Epithelial Tight Junctions
inferredcites →https://doi.org/10.1136/gut.2006.094375openalex-snapshot
Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease
inferredcites →https://doi.org/10.1136/gut.34.12.1705openalex-snapshot
Location of tumour necrosis factor alpha by immunohistochemistry in chronic inflammatory bowel disease.
inferredcites →https://doi.org/10.1136/gut.34.3.354openalex-snapshot
Intestinal permeability in patients with coeliac disease and relatives of patients with coeliac disease.
inferredcites →https://doi.org/10.1136/gut.45.1.70openalex-snapshot
Small intestinal transit, absorption, and permeability in patients with AIDS with and without diarrhoea
inferredcites →https://doi.org/10.1146/annurev.physiol.68.040104.131404openalex-snapshot
CLAUDINS AND EPITHELIAL PARACELLULAR TRANSPORT
inferredcites →https://doi.org/10.1152/ajpcell.1997.273.4.c1378openalex-snapshot
Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation
inferredcites →https://doi.org/10.1152/ajpgi.00055.2011openalex-snapshot
Occludin regulates macromolecule flux across the intestinal epithelial tight junction barrier
inferredcites →https://doi.org/10.1152/ajpgi.00243.2003openalex-snapshot
Total parenteral nutrition adversely affects gut barrier function in neonatal piglets
inferredcites →https://doi.org/10.1152/ajpgi.00386.2007openalex-snapshot
Decline in intestinal mucosal IL-10 expression and decreased intestinal barrier function in a mouse model of total parenteral nutrition
inferredcites →https://doi.org/10.1152/ajpgi.00412.2004openalex-snapshot
Mechanism of TNF-α modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression
inferredcites →https://doi.org/10.1152/ajpgi.00494.2010openalex-snapshot
ERK is involved in EGF-mediated protection of tight junctions, but not adherens junctions, in acetaldehyde-treated Caco-2 cell monolayers
inferredcites →https://doi.org/10.1152/ajpgi.2000.279.5.g851openalex-snapshot
IV. Regulation of tight junctions by extracellular stimuli: nutrients, cytokines, and immune cells
inferredcites →https://doi.org/10.1152/ajpgi.2001.280.6.g1280openalex-snapshot
Role of protein tyrosine phosphorylation in acetaldehyde-induced disruption of epithelial tight junctions
inferredcites →https://doi.org/10.1196/annals.1326.027openalex-snapshot
Disrupted Barrier Function through Epithelial Cell Apoptosis
inferredcites →https://doi.org/10.1242/jcs.112.1.137openalex-snapshot
Tumor necrosis factor-alpha (TNFα) regulates the epithelial barrier in the human intestinal cell line HT-29/B6
inferredcites →https://doi.org/10.1242/jcs.113.13.2363openalex-snapshot
Human junction adhesion molecule regulates tight junction resealing in epithelia
inferredcites →https://doi.org/10.2353/ajpath.2006.060681openalex-snapshot
Molecular Basis of Epithelial Barrier Regulation
inferredcites →https://doi.org/10.2353/ajpath.2010.100371openalex-snapshot
IL-1β-Induced Increase in Intestinal Epithelial Tight Junction Permeability Is Mediated by MEKK-1 Activation of Canonical NF-κB Pathway
inferredcites →https://doi.org/10.4049/jimmunol.180.8.5653openalex-snapshot
Mechanism of IL-1β-Induced Increase in Intestinal Epithelial Tight Junction Permeability

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1002/admt.202500065openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/advs.202103189openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/advs.202401172openalex-snapshot
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Elevated SPARC Disrupts the Intestinal Barrier Integrity in Crohn's Disease by Interacting with OTUD4 and Activating the MYD88/NF‐κB Pathway
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Mucus blocks probiotics but increases penetration of motile pathogens and induces TNF‐α and IL‐8 secretion
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inferred← citeshttps://doi.org/10.1002/fsn3.3124openalex-snapshot
Alleviative mechanism and effect of Bifidobacterium animalis A6 on dextran sodium sulfate‐induced ulcerative colitis in mice
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Collagen Peptides and Saccharomyces boulardii CNCM I‐745 Attenuate Acetic Acid‐Induced Colitis in Rats by Modulating Inflammation and Barrier Permeability
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Rumen Epithelial Transcriptome Analysis Revealed the Regulatory Mechanism of Host Adaptation to Nitrogen Source Replacement Diet in Simmental Cattle
inferred← citeshttps://doi.org/10.1002/hep.28817openalex-snapshot
The cystic fibrosis transmembrane conductance regulator controls biliary epithelial inflammation and permeability by regulating Src tyrosine kinase activity
inferred← citeshttps://doi.org/10.1002/jcb.27160openalex-snapshot
IL‐1β induces increased tight junction permeability in bovine mammary epithelial cells via the IL‐1β‐ERK1/2‐MLCK axis upon blood‐milk barrier damage
inferred← citeshttps://doi.org/10.1002/jcp.27489openalex-snapshot
MicroRNAs and signaling networks involved in epithelial–mesenchymal transition
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inferred← citeshttps://doi.org/10.1002/jsfa.10410openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/jsfa.11374openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/mnfr.201800159openalex-snapshot
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The GUT-Immune System
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Roasted garlic protects against leaky gut syndrome in dextran sodium sulfate-induced colitis mice
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LncRNA: A Potential Research Direction in Intestinal Barrier Function
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Vancomycin-Induced Changes in Host Immunity and Behavior: Comparative Genomic and Metagenomic Analysis in C57BL/6 and BALB/c Mice
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AhR activation protects intestinal epithelial barrier function through regulation of Par-6
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Auraptene Mitigates Colitis Induced by Dextran Sulfate Sodium in Mice by Regulating Specific Intestinal Flora and Repairing the Intestinal Barrier
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MicroRNA in gastrointestinal cell signalling
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Recent advances in the therapeutics and modes of action of a range of agents used to treat ulcerative colitis and related inflammatory conditions
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Lignosulfonic acid attenuates NF-κB activation and intestinal epithelial barrier dysfunction induced by TNF-α/IFN-γ in Caco-2 cells
inferred← citeshttps://doi.org/10.1007/s12079-022-00695-xopenalex-snapshot
Role of interleukin-6-mediated inflammation in the pathogenesis of inflammatory bowel disease: focus on the available therapeutic approaches and gut microbiome
inferred← citeshttps://doi.org/10.1007/s12088-022-01032-xopenalex-snapshot
Colonic Microflora Protagonist of Liver Metabolism and Gut Permeability: Study on Mice Model
inferred← citeshttps://doi.org/10.1007/s12274-024-6435-6openalex-snapshot
ROS-responsive nanoparticles targeting inflamed colon for synergistic therapy of inflammatory bowel disease via barrier repair and anti-inflammation
inferred← citeshttps://doi.org/10.1007/s12602-017-9275-9openalex-snapshot
The Effects of Direct-fed Microbial Supplementation, as an Alternative to Antibiotics, on Growth Performance, Intestinal Immune Status, and Epithelial Barrier Gene Expression in Broiler Chickens
inferred← citeshttps://doi.org/10.1007/s12602-017-9322-6openalex-snapshot
Probiotics and the Gut Immune System: Indirect Regulation
inferred← citeshttps://doi.org/10.1007/s12602-022-09923-7openalex-snapshot
Effects of Dietary Supplementation with Lactobacillus acidophilus and Bacillus subtilis on Mucosal Immunity and Intestinal Barrier Are Associated with Its Modulation of Gut Metabolites and Microbiota in Late-Phase Laying Hens
inferred← citeshttps://doi.org/10.1007/s12602-022-09924-6openalex-snapshot
Effects of Bacillus methylotrophicus SY200 Supplementation on Growth Performance, Antioxidant Status, Intestinal Morphology, and Immune Function in Broiler Chickens
inferred← citeshttps://doi.org/10.1007/s12602-022-09989-3openalex-snapshot
Diets Supplemented with Probiotics Improve the Performance of Broilers Exposed to Heat Stress from 15 Days of Age
inferred← citeshttps://doi.org/10.1007/s12602-023-10072-8openalex-snapshot
Understanding the Effect of Compound Probiotics on the Health of Rabbits and Its Mechanisms Through Metagenomics
inferred← citeshttps://doi.org/10.1007/s13258-021-01166-0openalex-snapshot
Keratin 1 maintains the intestinal barrier in ulcerative colitis
inferred← citeshttps://doi.org/10.1007/s13273-026-00655-1openalex-snapshot
Cinnamomum cassia extract restores intestinal barrier function via the regulation of tight junction proteins under IL-6-induced inflammatory conditions
inferred← citeshttps://doi.org/10.1007/s13353-024-00833-8openalex-snapshot
Assessing cytotoxicity and endoplasmic reticulum stress in human blood–brain barrier cells due to silver and copper oxide nanoparticles
inferred← citeshttps://doi.org/10.1007/s40489-019-00187-6openalex-snapshot
Potential Determinants of Gastrointestinal Dysfunction in Autism Spectrum Disorders
inferred← citeshttps://doi.org/10.1007/s43393-025-00383-yopenalex-snapshot
Beyond methanogenesis: Methanosarcina mazei in biotechnology and biomedical research
inferred← citeshttps://doi.org/10.1016/b978-0-12-810541-2.00002-6openalex-snapshot
The Gut Microbiota
inferred← citeshttps://doi.org/10.1016/b978-0-12-815249-2.00026-9openalex-snapshot
The Emerging Role of Microbiome–Gut–Brain Axis in Functional Gastrointestinal Disorders
inferred← citeshttps://doi.org/10.1016/b978-0-323-43044-9.00019-4openalex-snapshot
Intestinal Permeability
inferred← citeshttps://doi.org/10.1016/b978-0-323-90144-4.00001-xopenalex-snapshot
Intestinal barrier immunity: key players in the gut microbial “meet and greet or get-rid” event
inferred← citeshttps://doi.org/10.1016/b978-0-323-91387-4.00001-6openalex-snapshot
The Gut Microbiota
inferred← citeshttps://doi.org/10.1016/j.abb.2020.108409openalex-snapshot
Aronia berry inhibits disruption of Caco-2 intestinal barrier function
inferred← citeshttps://doi.org/10.1016/j.abb.2024.109978openalex-snapshot
Gallic acid mitigates intestinal inflammation and loss of tight junction protein expression using a 2D-Caco-2 and RAW 264.7 co-culture model
inferred← citeshttps://doi.org/10.1016/j.abb.2025.110592openalex-snapshot
Distinct interactions of proanthocyanidins of various degrees of polymerization with TLR4 receptor on the integrity of differentiating Caco-2 cell monolayers through tight junction protein expression
inferred← citeshttps://doi.org/10.1016/j.actbio.2018.09.061openalex-snapshot
Micro-patterned endogenous stroma equivalent induces polarized crypt-villus architecture of human small intestinal epithelium
inferred← citeshttps://doi.org/10.1016/j.ajpath.2017.08.015openalex-snapshot
Acrolein Disrupts Tight Junction Proteins and Causes Endoplasmic Reticulum Stress-Mediated Epithelial Cell Death Leading to Intestinal Barrier Dysfunction and Permeability
inferred← citeshttps://doi.org/10.1016/j.amjms.2018.01.002openalex-snapshot
Effects of Alpinetin on Intestinal Barrier Function, Inflammation and Oxidative Stress in Dextran Sulfate Sodium-Induced Ulcerative Colitis Mice
inferred← citeshttps://doi.org/10.1016/j.anai.2018.05.010openalex-snapshot
The role of gastrointestinal permeability in food allergy
inferred← citeshttps://doi.org/10.1016/j.anifeedsci.2020.114596openalex-snapshot
Dietary fermented soybean meal inclusion improves growth performance and ileal barrier function of the weaned piglets challenged by enterotoxigenic Escherichia coli K88
inferred← citeshttps://doi.org/10.1016/j.aninu.2021.01.008openalex-snapshot
Enteromorpha polysaccharide-zinc replacing prophylactic antibiotics contributes to improving gut health of weaned piglets
inferred← citeshttps://doi.org/10.1016/j.aninu.2022.09.010openalex-snapshot
Dietary coated essential oil and organic acid mixture supplementation improves health of broilers infected with avian pathogenic Escherichia coli
inferred← citeshttps://doi.org/10.1016/j.aninu.2022.10.008openalex-snapshot
Effects of β-alanine on intestinal development and immune performance of weaned piglets
inferred← citeshttps://doi.org/10.1016/j.aninu.2023.04.003openalex-snapshot
Maternal sodium acetate supplementation promotes lactation performance of sows and their offspring growth performance
inferred← citeshttps://doi.org/10.1016/j.aninu.2023.06.003openalex-snapshot
Dietary lysozyme improves growth performance and intestinal barrier function of weaned piglets
inferred← citeshttps://doi.org/10.1016/j.aninu.2024.06.006openalex-snapshot
Targeting gut microbiota and metabolism profiles with coated sodium butyrate to ameliorate high-energy and low-protein diet-induced intestinal barrier dysfunction in laying hens
inferred← citeshttps://doi.org/10.1016/j.aninu.2026.03.016openalex-snapshot
From energy substrate to guardian: the dual roles of short-chain fatty acids in gut health of animals
inferred← citeshttps://doi.org/10.1016/j.apsb.2024.02.020openalex-snapshot
5S-Heudelotinone alleviates experimental colitis by shaping the immune system and enhancing the intestinal barrier in a gut microbiota-dependent manner
inferred← citeshttps://doi.org/10.1016/j.aqrep.2021.100992openalex-snapshot
Re-aliment regains feed deprivation-induced microflora dysbiosis and immune stress in the gut of red swamp crayfish (Procambarus clarkii)
inferred← citeshttps://doi.org/10.1016/j.aqrep.2024.102232openalex-snapshot
Carp growth, body composition, lipidomics, and flesh quality in response to replacing dietary fish meal with a complex protein source
inferred← citeshttps://doi.org/10.1016/j.aqrep.2025.102854openalex-snapshot
Unveiling the metabolic transformation of Astragalus membranaceus through probiotic fermentation and its impact on growth and gut health in common carp (Cyprinus carpio)
inferred← citeshttps://doi.org/10.1016/j.aqrep.2026.103461openalex-snapshot
Dietary naringin attenuates adverse effects of high fat diet on growth performance, antioxidative capacity, inflammatory response and apoptosis in the intestine of largemouth bass (Micropterus salmoides)
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2022.738280openalex-snapshot
Stachyose protects intestinal mucosal barrier via promotion of tight junction and Lactobacillus casei-drived inhibition of apoptosis in juvenile turbot, Scophthalmus maximus L.
inferred← citeshttps://doi.org/10.1016/j.bbadis.2019.165534openalex-snapshot
Painful interactions: Microbial compounds and visceral pain
inferred← citeshttps://doi.org/10.1016/j.bbi.2026.107006openalex-snapshot
Disrupting peripheral serotonin synthesis drives sex-specific alterations in sociability and cognition, and reshapes the gut-immune-brain axis
inferred← citeshttps://doi.org/10.1016/j.bbih.2020.100048openalex-snapshot
Investigating the gut-brain axis in a neurodevelopmental rodent model of schizophrenia
inferred← citeshttps://doi.org/10.1016/j.bbrc.2026.154480openalex-snapshot
Selenium deficiency triggers intestinal ferroptosis in mice via oxidative stress
inferred← citeshttps://doi.org/10.1016/j.bcp.2023.115752openalex-snapshot
Treatment with S-adenosylmethionine ameliorates irinotecan-induced intestinal barrier dysfunction and intestinal microbial disorder in mice
inferred← citeshttps://doi.org/10.1016/j.beem.2021.101507openalex-snapshot
Gut microbiome, prebiotics, intestinal permeability and diabetes complications
inferred← citeshttps://doi.org/10.1016/j.biocel.2016.10.021openalex-snapshot
Tuning constitutive and pathological inflammation in the gut via the interaction of dietary nitrate and polyphenols with host microbiome
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2026.124146openalex-snapshot
Orally delivered, pH-resistant dual coated extracellular vesicles restore intestinal barrier function and suppress colitis
inferred← citeshttps://doi.org/10.1016/j.biopha.2017.11.125openalex-snapshot
Protective effects of polyphenol-rich infusions from carob (Ceratonia siliqua) leaves and cladodes of Opuntia ficus-indica against inflammation associated with diet-induced obesity and DSS-induced colitis in Swiss mice
inferred← citeshttps://doi.org/10.1016/j.biopha.2018.10.050openalex-snapshot
Ameliorative effect of Alnus japonica ethanol extract on colitis through the inhibition of inflammatory responses and attenuation of intestinal barrier disruption in vivo and in vitro
inferred← citeshttps://doi.org/10.1016/j.biopha.2021.111426openalex-snapshot
Herbal medicine WangShiBaoChiWan improves gastrointestinal health in mice via modulation of intestinal tight junctions and gut microbiota and inhibition of inflammation
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.117518openalex-snapshot
Farnesol ameliorates DSS-induced IBD by regulating inflammatory cytokines, repairing the intestinal barrier, reversing the gut microbiota imbalance, and influencing fecal metabolome in C57BL/6 mice
inferred← citeshttps://doi.org/10.1016/j.carbpol.2021.117876openalex-snapshot
Polysaccharides in natural products that repair the damage to intestinal mucosa caused by cyclophosphamide and their mechanisms: A review
inferred← citeshttps://doi.org/10.1016/j.carbpol.2026.125838openalex-snapshot
Generational shifts in thiolated cyclodextrins: Toward more efficient drug delivery systems
inferred← citeshttps://doi.org/10.1016/j.cbi.2022.110316openalex-snapshot
Protective effect of 7-hydroxyl-1-methylindole-3-acetonitrile on the intestinal mucosal damage response to inflammation in mice with DSS-induced colitis
inferred← citeshttps://doi.org/10.1016/j.cbi.2026.111907openalex-snapshot
Imiquimod-induced colitis: A novel ROS/ERK-driven model of intestinal inflammation and barrier dysfunction
inferred← citeshttps://doi.org/10.1016/j.cbi.2026.112291openalex-snapshot
Endoplasmic reticulum stress is involved in chronic chlorpyrifos-induced jejunal barrier injury in weaned mice
inferred← citeshttps://doi.org/10.1016/j.cbpc.2025.110370openalex-snapshot
Selenium ameliorates fumonisin B1-induced mitochondrial dysfunction and barrier impairment in porcine intestinal epithelial cells
inferred← citeshttps://doi.org/10.1016/j.cclet.2024.110224openalex-snapshot
Phytoconstituent-derived nano-medicines/vesicles providing a promising dawn for inflammatory bowel disease
inferred← citeshttps://doi.org/10.1016/j.cej.2024.157800openalex-snapshot
Biocompatible carbon dots nanozymes as ROS/RNS modulators for ulcerative colitis alleviation by comprehensively orchestrating intestinal homeostasis
inferred← citeshttps://doi.org/10.1016/j.cellimm.2024.104912openalex-snapshot
Sodium butyrate prevents lipopolysaccharide induced inflammation and restores the expression of tight junction protein in human epithelial Caco-2 cells
inferred← citeshttps://doi.org/10.1016/j.chemosphere.2020.129130openalex-snapshot
Dose-dependent effects of lead induced gut injuries: An in vitro and in vivo study
inferred← citeshttps://doi.org/10.1016/j.chemosphere.2021.129607openalex-snapshot
Intestinal changes associated with fluoride exposure in rats: Integrative morphological, proteomic and microbiome analyses
inferred← citeshttps://doi.org/10.1016/j.chemosphere.2021.132556openalex-snapshot
Aluminum induced intestinal dysfunction via mechanical, immune, chemical and biological barriers
inferred← citeshttps://doi.org/10.1016/j.cimid.2021.101611openalex-snapshot
Effect of rifaximin on gut-lung axis in mice infected with influenza A virus
inferred← citeshttps://doi.org/10.1016/j.clnu.2020.12.014openalex-snapshot
A polyphenol-rich dietary pattern improves intestinal permeability, evaluated as serum zonulin levels, in older subjects: The MaPLE randomised controlled trial
inferred← citeshttps://doi.org/10.1016/j.crfs.2025.101188openalex-snapshot
Functional evaluation of synbiotic combination of Kluyveromyces marxianus and Lentilactobacillus kefiri derived from milk kefir using multi-omics approaches
inferred← citeshttps://doi.org/10.1016/j.crtox.2025.100217openalex-snapshot
Exacerbation of polyethylene microplastics in animal models of DSS-induced colitis through damage to intestinal epithelial cell conjunctions
inferred← citeshttps://doi.org/10.1016/j.dci.2026.105592openalex-snapshot
Effects of dietary chromium propionate on growth performance, intestinal barrier function, and intestinal immune response in broilers
inferred← citeshttps://doi.org/10.1016/j.drudis.2016.03.007openalex-snapshot
Curcumin as a therapeutic agent in the chemoprevention of inflammatory bowel disease
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2020.111072openalex-snapshot
Changes in intestinal barrier functions and gut microbiota in rats exposed to zearalenone
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2022.114152openalex-snapshot
Gut dysfunction may be the source of pathological aggregation of alpha-synuclein in the central nervous system through Paraquat exposure in mice
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2022.114364openalex-snapshot
Ferric citrate-induced colonic mucosal damage associated with oxidative stress, inflammation responses, apoptosis, and the changes of gut microbial composition
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2023.115154openalex-snapshot
Herbicide propisochlor exposure induces intestinal barrier impairment, microbiota dysbiosis and gut pyroptosis
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2024.116750openalex-snapshot
Exposure to microcystin-LR promotes the progression of colitis-associated colorectal cancer by inducing barrier disruption and gut microbiota dysbiosis
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2025.119540openalex-snapshot
Epigenomic determinants of ferroptosis via oxidative stress in IPEC-J2 cells exposed to Ochratoxin A
inferred← citeshttps://doi.org/10.1016/j.ejpb.2021.03.013openalex-snapshot
The effect of hypergravity in intestinal permeability of nanoformulations and molecules
inferred← citeshttps://doi.org/10.1016/j.ejphar.2022.175152openalex-snapshot
Role of a mixed probiotic product, VSL#3, in the prevention and treatment of colorectal cancer
inferred← citeshttps://doi.org/10.1016/j.ejphar.2025.177707openalex-snapshot
Calycosin regulates gut microbiota-bile acid-FXR axis to protect rats from cerebral ischemia-reperfusion injury
inferred← citeshttps://doi.org/10.1016/j.endien.2020.01.010openalex-snapshot
A food pyramid, based on a review of the emerging literature, for subjects with inflammatory bowel disease
inferred← citeshttps://doi.org/10.1016/j.endinu.2020.01.004openalex-snapshot
A food pyramid, based on a review of the emerging literature, for subjects with inflammatory bowel disease
inferred← citeshttps://doi.org/10.1016/j.fbio.2024.104833openalex-snapshot
Enhancing intestinal health with germinated oats: Bioinformatics and compound profiling insights into a novel approach for managing inflammatory bowel disease
inferred← citeshttps://doi.org/10.1016/j.fbio.2024.105816openalex-snapshot
Alcohol aggravates metabolic fatty liver in high-fat diet mice via gut microbiota and metabolite-mediated TLR4/NF-κB and MCT1/GPR pathways
inferred← citeshttps://doi.org/10.1016/j.fbio.2025.107614openalex-snapshot
Alleviating effect and mechanism of Lactobacillus helveticus ZJUIDS18 on colitis induced by DSS in mice
inferred← citeshttps://doi.org/10.1016/j.fbio.2026.109669openalex-snapshot
Effects of sucralose on microbial and intestinal epithelial activity
inferred← citeshttps://doi.org/10.1016/j.fct.2017.08.002openalex-snapshot
Oxyresveratrol improves tight junction integrity through the PKC and MAPK signaling pathways in Caco-2 cells
inferred← citeshttps://doi.org/10.1016/j.fct.2018.12.015openalex-snapshot
Skim milk powder with high content of Maillard reaction products affect weight gain, organ development and intestinal inflammation in early life in rats
inferred← citeshttps://doi.org/10.1016/j.fct.2020.111729openalex-snapshot
Altered paracellular permeability in intestinal cell monolayer challenged with lipopolysaccharide: Modulatory effects of pterostilbene metabolites
inferred← citeshttps://doi.org/10.1016/j.fitote.2019.104419openalex-snapshot
Acmella oleracea for pain management
inferred← citeshttps://doi.org/10.1016/j.fitote.2025.106944openalex-snapshot
Fermented beet juice reinforces tight junctions and alleviates colitis via multi-pathway regulation
inferred← citeshttps://doi.org/10.1016/j.foodchem.2021.129019openalex-snapshot
Thermal or membrane processing for Infant Milk Formula: Effects on protein digestion and integrity of the intestinal barrier
inferred← citeshttps://doi.org/10.1016/j.foodchem.2025.144914openalex-snapshot
Enhancement in the intestinal absorption of ginsenoside Re by ginseng polysaccharides and its mechanisms
inferred← citeshttps://doi.org/10.1016/j.foodres.2020.109240openalex-snapshot
Transport, metabolism and remedial potential of functional food extracts (FFEs) in Caco-2 cells monolayer: A review
inferred← citeshttps://doi.org/10.1016/j.foodres.2020.109409openalex-snapshot
Ameliorative effects of L-theanine on dextran sulfate sodium induced colitis in C57BL/6J mice are associated with the inhibition of inflammatory responses and attenuation of intestinal barrier disruption
inferred← citeshttps://doi.org/10.1016/j.foodres.2021.110287openalex-snapshot
Potential mechanistic pathways underlying intestinal and hepatic effects of kefir in high-fructose-fed rats
inferred← citeshttps://doi.org/10.1016/j.foodres.2022.112362openalex-snapshot
Pingyin Rose Essential Oil Restores Intestinal Barrier Integrity in DSS-induced Mice Colitis Model
inferred← citeshttps://doi.org/10.1016/j.foodres.2023.112477openalex-snapshot
Protective effect of Paecilomyces cicadae TJJ11213 exopolysaccharide on intestinal mucosa and regulation of gut microbiota in immunosuppressed mice
inferred← citeshttps://doi.org/10.1016/j.foodres.2026.118686openalex-snapshot
Quercetin ameliorates intestinal barrier dysfunction by suppressing the PKCα/MLCK signaling pathway in piglets
inferred← citeshttps://doi.org/10.1016/j.foodres.2026.119200openalex-snapshot
Fructooligosaccharides alleviate early-life antibiotic-exposed food allergy via the Indole-3-propionic acid-AhR-Nrf2 Axis: A multi-omics prospective cohort study
inferred← citeshttps://doi.org/10.1016/j.fshw.2023.03.027openalex-snapshot
Therapeutic potential and mechanism of functional oligosaccharides in inflammatory bowel disease: a review
inferred← citeshttps://doi.org/10.1016/j.fshw.2023.03.041openalex-snapshot
Stachyose modulates gut microbiota and alleviates DSS-induced ulcerative colitis in mice
inferred← citeshttps://doi.org/10.1016/j.fsi.2018.04.004openalex-snapshot
Soya-saponins induce intestinal inflammation and barrier dysfunction in juvenile turbot (Scophthalmus maximus)
inferred← citeshttps://doi.org/10.1016/j.fsi.2019.09.069openalex-snapshot
Zinc alleviates arsenism in common carp: Varied change profiles of cytokines and tight junction proteins among two intestinal segments
inferred← citeshttps://doi.org/10.1016/j.fsi.2025.110535openalex-snapshot
Nuciferine supplement improved intestinal function and inflammatory response in juvenile large yellow croaker (Larmichthys crocea) fed diets with high palm oil level
inferred← citeshttps://doi.org/10.1016/j.fsi.2025.110683openalex-snapshot
ILA mitigates HFD-induced metabolic dysfunction via lipid-immune crosstalk and gut microbiota modulation in zebrafish
inferred← citeshttps://doi.org/10.1016/j.gene.2017.01.015openalex-snapshot
Critical role of Keratin 1 in maintaining epithelial barrier and correlation of its down-regulation with the progression of inflammatory bowel disease
inferred← citeshttps://doi.org/10.1016/j.hal.2020.101849openalex-snapshot
Cyanobacterial lipopeptides puwainaphycins and minutissamides induce disruptive and pro-inflammatory processes in Caco-2 human intestinal barrier model
inferred← citeshttps://doi.org/10.1016/j.heliyon.2022.e11340openalex-snapshot
Microbial and host factors contribute to bloodstream infection in a pediatric acute lymphocytic leukemia mouse model
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2019.06.041openalex-snapshot
Surface-layer protein from Lactobacillus acidophilus NCFM attenuates tumor necrosis factor-α-induced intestinal barrier dysfunction and inflammation
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2020.06.203openalex-snapshot
Effects of the polysaccharide SPS-3-1 purified from Spirulina on barrier integrity and proliferation of Caco-2 cells
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2020.11.144openalex-snapshot
Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2021.02.186openalex-snapshot
Protective effect of exopolysaccharide fraction from Bacillus subtilis against dextran sulfate sodium-induced colitis through maintenance of intestinal barrier and suppression of inflammatory responses
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2023.124689openalex-snapshot
Angelica sinensis aboveground part polysaccharide and its metabolite 5-MT ameliorate colitis via modulating gut microbiota and TLR4/MyD88/NF-κB pathway
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2023.124866openalex-snapshot
Arabinogalactan ameliorates benzo[a]pyrene-induced intestinal epithelial barrier dysfunction via AhR/MAPK signaling pathway
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.130863openalex-snapshot
Sporisorium reilianum polysaccharides improve DSS-induced ulcerative colitis by regulating intestinal barrier function and metabolites
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.136691openalex-snapshot
Effects of traditional Chinese medicine polysaccharides on chronic diseases by modulating gut microbiota: A review
inferred← citeshttps://doi.org/10.1016/j.intimp.2016.07.020openalex-snapshot
Hydrogen sulfide improves colonic barrier integrity in DSS-induced inflammation in Caco-2 cells and mice
inferred← citeshttps://doi.org/10.1016/j.intimp.2018.04.006openalex-snapshot
Oregonin inhibits inflammation and protects against barrier disruption in intestinal epithelial cells
inferred← citeshttps://doi.org/10.1016/j.intimp.2019.105977openalex-snapshot
Autophagy induction by rapamycin ameliorates experimental colitis and improves intestinal epithelial barrier function in IL-10 knockout mice
inferred← citeshttps://doi.org/10.1016/j.intimp.2021.107802openalex-snapshot
Tilapia head glycolipids protect mice against dextran sulfate sodium-induced colitis by ameliorating the gut barrier and suppressing NF-kappa B signaling pathway
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.111319openalex-snapshot
Mannose attenuates intestinal epithelial tight junction damage in experimental colitis mice by activating the AXIN-AMPK pathway
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.111386openalex-snapshot
Synthesis and antibacterial activity of FST and its effects on inflammatory response and intestinal barrier function in mice infected with Escherichia coli O78
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112990openalex-snapshot
PROTAC based STING degrader attenuates acute colitis by inhibiting macrophage M1 polarization and intestinal epithelial cells pyroptosis mediated by STING-NLRP3 axis
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.113174openalex-snapshot
Formononetin ameliorates dextran sulfate sodium-induced colitis via enhancing antioxidant capacity, promoting tight junction protein expression and reshaping M1/M2 macrophage polarization balance
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.115144openalex-snapshot
Cardamonin alleviates intestinal inflammation in LPS-induced weaned piglets through the AhR/Nrf2/NLRP3 signaling pathway
inferred← citeshttps://doi.org/10.1016/j.intimp.2026.117514openalex-snapshot
Kaempferol-3-O-glucorhamnoside alleviates DSS-induced ulcerative colitis via the arginine-polyamine metabolism pathway
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