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The Importance of Cancer Cell Lines as in vitro Models in Cancer Methylome Analysis and Anticancer Drugs Testing

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Widespread intraspecies cross-contamination of human tumor cell lines arising at source

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Role of hMLH1 promoter hypermethylation in drug resistance to 5‐fluorouracil in colorectal cancer cell lines

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Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine

inferredcites →https://doi.org/10.1002/path.1024openalex-snapshot

Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours

inferredcites →https://doi.org/10.1007/bf01807363openalex-snapshot

Biological differences among MCF-7 human breast cancer cell lines from different laboratories

inferredcites →https://doi.org/10.1007/s10585-008-9169-zopenalex-snapshot

Characterisation of breast cancer cell lines and establishment of a novel isogenic subclone to study migration, invasion and tumourigenicity

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The use of human cancer cell lines as a primary screening system for antineoplastic compounds

inferredcites →https://doi.org/10.1016/j.bbcan.2008.12.004openalex-snapshot

Human cancer cell lines: Experimental models for cancer cells in situ? For cancer stem cells?

inferredcites →https://doi.org/10.1016/j.ccr.2006.10.008openalex-snapshot

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

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Decitabine—Bedside to bench

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Anti-hepatocellular carcinoma activity using human HepG2 cells and hepatotoxicity of 6-substituted methyl 3-aminothieno[3,2-b]pyridine-2-carboxylate derivatives: In vitro evaluation, cell cycle analysis and QSAR studies

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Establishment and characterization of a rabbit oral squamous cell carcinoma cell line as a model for in vivo studies

inferredcites →https://doi.org/10.1016/s1521-6616(03)00207-9openalex-snapshot

Inhibitors of DNA methylation in the treatment of hematological malignancies and MDS

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Direct Analysis of Tubulin Expression in Cancer Cell Lines by Electrospray Ionization Mass Spectrometry

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Breast Cancer Research and Treatment

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Cell Cycle Checkpoints as Therapeutic Targets

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Relevance of Breast Cancer Cell Lines as Models for Breast Tumours: An Update

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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Nanovector delivery of siRNA for cancer therapy

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Induction of DNA methylation and gene silencing by short interfering RNAs in human cells

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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

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Systematic identification of genomic markers of drug sensitivity in cancer cells

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Microtubules as a target for anticancer drugs

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Targeting polo-like kinase 1 for cancer therapy

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The NCI60 human tumour cell line anticancer drug screen

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Modelling breast cancer: one size does not fit all

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Promoter methylation of P16, RARβ, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing

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DNA methylation in the promoter region of the p16 (CDKN2/MTS-1/INK4A) gene in human breast tumours

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Detailed methylation analysis of the glutathione S-transferase π (GSTP1) gene in prostate cancer

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DNA methylation in cancer: too much, but also too little

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5-Aza-2′-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivation

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High-resolution mapping of DNA copy alterations in human chromosome 22 using high-density tiling oligonucleotide arrays

inferredcites →https://doi.org/10.1093/annonc/mdf314openalex-snapshot

DNA methyltransferase inhibitors—state of the art

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Advantages of next-generation sequencing versus the microarray in epigenetic research

inferredcites →https://doi.org/10.1093/bfgp/elq035openalex-snapshot

Next generation sequencing based approaches to epigenomics

inferredcites →https://doi.org/10.1093/bioinformatics/btq040openalex-snapshot

SNVMix: predicting single nucleotide variants from next-generation sequencing of tumors

inferredcites →https://doi.org/10.1093/clinchem/45.8.1148openalex-snapshot

Real-Time Reverse Transcription-PCR Assay for Future Management of ERBB2-based Clinical Applications

inferredcites →https://doi.org/10.1093/hmg/10.7.687openalex-snapshot

Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

inferredcites →https://doi.org/10.1093/jnci/92.7.564openalex-snapshot

Promoter Hypermethylation and BRCA1 Inactivation in Sporadic Breast and Ovarian Tumors

inferredcites →https://doi.org/10.1093/jnci/93.9.691openalex-snapshot

Epigenetic Inactivation of RASSF1A in Lung and Breast Cancers and Malignant Phenotype Suppression

inferredcites →https://doi.org/10.1093/jnci/djq279openalex-snapshot

Lung Cancer Cell Lines as Tools for Biomedical Discovery and Research

inferredcites →https://doi.org/10.1111/j.1349-7006.2003.tb01345.xopenalex-snapshot

Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal

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Chromosomal number aberrations and transformation in adult mouse retinal stem cells in vitro

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DNA Methylation Inhibitor 5-Aza-2′-Deoxycytidine Induces Reversible Genome-Wide DNA Damage That Is Distinctly Influenced by DNA Methyltransferases 1 and 3B

inferredcites →https://doi.org/10.1136/jmedgenet-2011-100242openalex-snapshot

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inferredcites →https://doi.org/10.1158/0008-5472.can-05-2853openalex-snapshot

BRCA1 Mutation Analysis of 41 Human Breast Cancer Cell Lines Reveals Three New Deleterious Mutants

inferredcites →https://doi.org/10.1158/0008-5472.can-06-0343openalex-snapshot

Down-regulation of Polo-like Kinase 1 Elevates Drug Sensitivity of Breast Cancer CellsIn vitroandIn vivo

inferredcites →https://doi.org/10.1158/0008-5472.can-06-0594openalex-snapshot

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inferredcites →https://doi.org/10.1158/0008-5472.can-07-1502openalex-snapshot

Drug Sensitivity Prediction by CpG Island Methylation Profile in the NCI-60 Cancer Cell Line Panel

inferredcites →https://doi.org/10.1158/0008-5472.can-07-2703openalex-snapshot

Genetic Alterations in the Tyrosine Kinase Transcriptome of Human Cancer Cell Lines

inferredcites →https://doi.org/10.1158/1078-0432.ccr-06-2218openalex-snapshot

Potent siRNA Inhibitors of Ribonucleotide Reductase Subunit RRM2 Reduce Cell Proliferation In vitro and In vivo

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Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays

inferredcites →https://doi.org/10.1158/1535-7163.mct-05-0536openalex-snapshot

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Mutation analysis of 24 known cancer genes in the NCI-60 cell line set

inferredcites →https://doi.org/10.1167/iovs.08-3091openalex-snapshot

Chromosomal Number Aberrations and Transformation in Adult Mouse Retinal Stem Cells In Vitro

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Genome-wide analysis of aberrant methylation in human breast cancer cells using methyl-DNA immunoprecipitation combined with high-throughput sequencing

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inferredcites →https://doi.org/10.1371/journal.pone.0006146openalex-snapshot

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inferredcites →https://doi.org/10.1371/journal.pone.0009201openalex-snapshot

Delineating Genetic Alterations for Tumor Progression in the MCF10A Series of Breast Cancer Cell Lines

inferredcites →https://doi.org/10.1371/journal.pone.0011379openalex-snapshot

Methylation of the Tumor Suppressor Protein, BRCA1, Influences Its Transcriptional Cofactor Function

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КЛЕТОЧНЫЕ ТЕХНОЛОГИИ В ФАРМАКОЛОГИЧЕСКИХ ИССЛЕДОВАНИЯХ. НАСТОЯЩЕЕ И БУДУЩЕЕ, "Цитология"

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