On the public citation graph

Pharmacological rescue of cilia trafficking defects in IFT140 retinal organoid and RPE models of retinal dystrophy

https://doi.org/10.64898/2026.04.29.720656
0 signed · 54 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.
Claim with ORCID
Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.
See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/cm.21823openalex-snapshot
Intraflagellar transport: A critical player in photoreceptor development and the pathogenesis of retinal degenerative diseases
inferredcites →https://doi.org/10.1002/jcp.28519openalex-snapshot
Disease mechanisms and neuroprotection by tauroursodeoxycholic acid in Rpgr knockout mice
inferredcites →https://doi.org/10.1007/978-1-0716-3507-0_12openalex-snapshot
Affinity Purification of Intraflagellar Transport (IFT) Proteins in Mice Using Endogenous Streptavidin/FLAG Tags
inferredcites →https://doi.org/10.1007/s00439-015-1586-xopenalex-snapshot
Mutations in human IFT140 cause non-syndromic retinal degeneration
inferredcites →https://doi.org/10.1016/bs.mcb.2020.05.006openalex-snapshot
Ultrastructure expansion microscopy (U-ExM)
inferredcites →https://doi.org/10.1016/j.ajhg.2012.03.006openalex-snapshot
Mainzer-Saldino Syndrome Is a Ciliopathy Caused by IFT140 Mutations
inferredcites →https://doi.org/10.1016/j.ajhg.2021.11.016openalex-snapshot
Monoallelic IFT140 pathogenic variants are an important cause of the autosomal dominant polycystic kidney-spectrum phenotype
inferredcites →https://doi.org/10.1016/j.ajhg.2025.08.017openalex-snapshot
RetiGene, a comprehensive gene atlas for inherited retinal diseases
inferredcites →https://doi.org/10.1016/j.cell.2022.11.010openalex-snapshot
IFT-A structure reveals carriages for membrane protein transport into cilia
inferredcites →https://doi.org/10.1016/j.cell.2022.11.033openalex-snapshot
Mechanism of IFT-A polymerization into trains for ciliary transport
inferredcites →https://doi.org/10.1016/j.cell.2022.12.005openalex-snapshot
The gymnastics of intraflagellar transport complexes keeps trains running inside cilia
inferredcites →https://doi.org/10.1016/j.cell.2024.06.041openalex-snapshot
Extensive structural rearrangement of intraflagellar transport trains underpins bidirectional cargo transport
inferredcites →https://doi.org/10.1016/j.ekir.2024.06.021openalex-snapshot
Importance of IFT140 in Patients with Polycystic Kidney Disease Without a Family History
inferredcites →https://doi.org/10.1016/j.ekir.2025.04.060openalex-snapshot
Prostaglandin Analogs and Eupatilin as Treatments for Nephronophthisis
inferredcites →https://doi.org/10.1016/j.mcpro.2025.100916openalex-snapshot
Ciliopathy-Associated Missense Mutations in IFT140 are Tolerated by the Inherent Resilience of the IFT Machinery
inferredcites →https://doi.org/10.1038/nmeth.1591openalex-snapshot
A more efficient method to generate integration-free human iPS cells
inferredcites →https://doi.org/10.1038/nmeth.2019openalex-snapshot
Fiji: an open-source platform for biological-image analysis
inferredcites →https://doi.org/10.1038/nprot.2018.007openalex-snapshot
Simultaneous reprogramming and gene editing of human fibroblasts
inferredcites →https://doi.org/10.1038/s41420-025-02769-2openalex-snapshot
Preventing light-induced toxicity in a new mouse model of sector retinitis pigmentosa caused by Rhodopsin M39R variant
inferredcites →https://doi.org/10.1038/s41422-023-00778-3openalex-snapshot
Human IFT-A complex structures provide molecular insights into ciliary transport
inferredcites →https://doi.org/10.1038/s41467-017-00111-8openalex-snapshot
Gelsolin dysfunction causes photoreceptor loss in induced pluripotent cell and animal retinitis pigmentosa models
inferredcites →https://doi.org/10.1038/s41467-024-48846-5openalex-snapshot
Downregulation of rhodopsin is an effective therapeutic strategy in ameliorating peripherin-2-associated inherited retinal disorders
inferredcites →https://doi.org/10.1038/s41576-023-00587-9openalex-snapshot
Primary cilia as dynamic and diverse signalling hubs in development and disease
inferredcites →https://doi.org/10.1038/s41594-022-00905-5openalex-snapshot
The molecular structure of IFT-A and IFT-B in anterograde intraflagellar transport trains
inferredcites →https://doi.org/10.1038/s43856-025-00847-1openalex-snapshot
Drug and siRNA screens identify ROCK2 as a therapeutic target for ciliopathies
inferredcites →https://doi.org/10.1038/s44318-024-00284-1openalex-snapshot
Glutamylation imbalance impairs the molecular architecture of the photoreceptor cilium
inferredcites →https://doi.org/10.1038/srep34646openalex-snapshot
The trafficking of bacterial type rhodopsins into the Chlamydomonas eyespot and flagella is IFT mediated
inferredcites →https://doi.org/10.1053/j.ajkd.2023.08.019openalex-snapshot
Monoallelic Loss-of-Function IFT140 Pathogenic Variants Cause Autosomal Dominant Polycystic Kidney Disease: A Confirmatory Study With Suspicion of an Additional Cardiac Phenotype
inferredcites →https://doi.org/10.1053/j.ajkd.2025.08.006openalex-snapshot
Monoallelic IFT140 Variants Causing Childhood-Onset Autosomal Dominant Polycystic Kidney Disease
inferredcites →https://doi.org/10.1073/pnas.1903125117openalex-snapshot
PCARE and WASF3 regulate ciliary F-actin assembly that is required for the initiation of photoreceptor outer segment disk formation
inferredcites →https://doi.org/10.1074/jbc.m116.738658openalex-snapshot
Loss of ift122, a Retrograde Intraflagellar Transport (IFT) Complex Component, Leads to Slow, Progressive Photoreceptor Degeneration Due to Inefficient Opsin Transport
inferredcites →https://doi.org/10.1091/mbc.e07-08-0749openalex-snapshot
Intraflagellar Transport and Functional Analysis of Genes Required for Flagellum Formation in Trypanosomes
inferredcites →https://doi.org/10.1091/mbc.e16-11-0813openalex-snapshot
Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein–coupled receptors
inferredcites →https://doi.org/10.1091/mbc.e20-03-0190openalex-snapshot
Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone
inferredcites →https://doi.org/10.1093/ckj/sfae026openalex-snapshot
Monoallelic pathogenic IFT140 variants are a common cause of autosomal dominant polycystic kidney disease–spectrum phenotype
inferredcites →https://doi.org/10.1093/hmg/ddaf029openalex-snapshot
A novel recurrent ARL3 variant c.209G > A p.(Gly70Glu) causes variable non-syndromic dominant retinal dystrophy with defective lipidated protein transport in human retinal stem cell models
inferredcites →https://doi.org/10.1093/hmg/ddu509openalex-snapshot
Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells
inferredcites →https://doi.org/10.1093/hmg/ddv123openalex-snapshot
CEP290 alleles in mice disrupt tissue-specific cilia biogenesis and recapitulate features of syndromic ciliopathies
inferredcites →https://doi.org/10.1093/hmg/ddx245openalex-snapshot
Arl3 and RP2 regulate the trafficking of ciliary tip kinesins
inferredcites →https://doi.org/10.1101/2023.06.07.544132openalex-snapshot
Autonomous and non-cell autonomous etiology of ciliopathy associated structural birth defects
inferredcites →https://doi.org/10.1101/cshperspect.a028134openalex-snapshot
Open Sesame: How Transition Fibers and the Transition Zone Control Ciliary Composition
inferredcites →https://doi.org/10.1111/j.1600-0854.2009.00896.xopenalex-snapshot
Photoreceptor IFT Complexes Containing Chaperones, Guanylyl Cyclase 1 and Rhodopsin
inferredcites →https://doi.org/10.1124/molpharm.120.000072openalex-snapshot
Protective Effects of Flavonoids in Acute Models of Light-Induced Retinal Degeneration
inferredcites →https://doi.org/10.1140/epje/s10189-021-00031-yopenalex-snapshot
CiliaQ: a simple, open-source software for automated quantification of ciliary morphology and fluorescence in 2D, 3D, and 4D images
inferredcites →https://doi.org/10.1159/000539176openalex-snapshot
The First Pediatric Case of an IFT140 Heterozygous Deletion Causing Autosomal Dominant Polycystic Kidney Disease: Case Report
inferredcites →https://doi.org/10.1167/iovs.12-9662openalex-snapshot
The Rd8 Mutation of the Crb1 Gene Is Present in Vendor Lines of C57BL/6N Mice and Embryonic Stem Cells, and Confounds Ocular Induced Mutant Phenotypes
inferredcites →https://doi.org/10.1167/iovs.15-17976openalex-snapshot
Nonsyndromic Retinal Dystrophy due to Bi-Allelic Mutations in the Ciliary Transport Gene IFT140
inferredcites →https://doi.org/10.1172/jci.insight.169162openalex-snapshot
Gene augmentation of LCA5-associated Leber congenital amaurosis ameliorates bulge region defects of the photoreceptor ciliary axoneme
inferredcites →https://doi.org/10.1172/jci99232openalex-snapshot
Eupatilin rescues ciliary transition zone defects to ameliorate ciliopathy-related phenotypes
inferredcites →https://doi.org/10.1186/s40478-025-01943-yopenalex-snapshot
Small molecule treatment alleviates photoreceptor cilia defects in LCA5-deficient human retinal organoids
inferredcites →https://doi.org/10.1371/journal.pgen.1003746openalex-snapshot
Cauli: A Mouse Strain with an Ift140 Mutation That Results in a Skeletal Ciliopathy Modelling Jeune Syndrome
inferredcites →https://doi.org/10.1681/asn.2011080829openalex-snapshot
Disruption of IFT Complex A Causes Cystic Kidneys without Mitotic Spindle Misorientation
inferredcites →https://doi.org/10.3390/cells12121575openalex-snapshot
Eupatilin Improves Cilia Defects in Human CEP290 Ciliopathy Models
inferredcites →https://doi.org/10.3390/ijms25031839openalex-snapshot
AAV-RPGR Gene Therapy Rescues Opsin Mislocalisation in a Human Retinal Organoid Model of RPGR-Associated X-Linked Retinitis Pigmentosa
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.