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Multi-omic analysis identifies mitochondrial dysfunction as a conserved driver of acute severity and long-term complications in RSV infection

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Metabolomic and Immunological Profiling of Respiratory Syncytial Virus Infection after Intranasal Immunization with a Subunit Vaccine Candidate
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A comprehensive SARS-CoV-2 and COVID-19 review, Part 1: Intracellular overdrive for SARS-CoV-2 infection
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The genomic evolutionary dynamics and global circulation patterns of respiratory syncytial virus
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Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight
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Space radiation damage rescued by inhibition of key spaceflight associated miRNAs
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Genetic diversity and molecular evolution of human respiratory syncytial virus A and B
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Mitochondrial antioxidants abate SARS-COV-2 pathology in mice
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Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes
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Quantitative Proteomic Analysis of A549 Cells Infected with Human Respiratory Syncytial Virus
inferredcites →https://doi.org/10.1074/mcp.m114.041129openalex-snapshot
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Importance of De Novo Gene Evolution to Emerging Viral Threats: The ORF10 Strain-Restricted Orphan Gene of SARS-CoV-2 Promotes Pathogenesis
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limma powers differential expression analyses for RNA-sequencing and microarray studies
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Targeted Down Regulation Of Core Mitochondrial Genes During SARS-CoV-2 Infection
inferredcites →https://doi.org/10.1111/apm.13095openalex-snapshot
Serum metabolomic profiling reveals important difference between infants with and without subsequent recurrent wheezing in later childhood after RSV bronchiolitis
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Obesity‐Induced Metabolic Priming Exacerbates SARS ‐ CoV ‐2 Inflammation
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Single-cell profiling demonstrates the combined effect of wheeze phenotype and infant viral infection on airway epithelial development
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Mitochondrial dysfunction enhances influenza pathogenesis by up-regulating de novo sialic acid biosynthesis
inferredcites →https://doi.org/10.1126/science.1250684openalex-snapshot
mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity
inferredcites →https://doi.org/10.1126/science.aba9301openalex-snapshot
Neutrophilic inflammation in the respiratory mucosa predisposes to RSV infection
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COVID-19 can affect the heart
inferredcites →https://doi.org/10.1126/scitranslmed.abq1533openalex-snapshot
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
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Multiple Respiratory Syncytial Virus (RSV) Strains Infecting HEp-2 and A549 Cells Reveal Cell Line-Dependent Differences in Resistance to RSV Infection
inferredcites →https://doi.org/10.1152/ajplung.00192.2012openalex-snapshot
Antioxidant mimetics modulate oxidative stress and cellular signaling in airway epithelial cells infected with respiratory syncytial virus
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ZNFX1 Functions as a Master Regulator of Epigenetically Induced Pathogen Mimicry and Inflammasome Signaling in Cancer
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Viral-mediated Inhibition of Antioxidant Enzymes Contributes to the Pathogenesis of Severe Respiratory Syncytial Virus Bronchiolitis
inferredcites →https://doi.org/10.1165/rcmb.2008-0330ocopenalex-snapshot
Respiratory Syncytial Virus Induces Oxidative Stress by Modulating Antioxidant Enzymes
inferredcites →https://doi.org/10.1186/s13059-014-0550-8openalex-snapshot
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
inferredcites →https://doi.org/10.1371/journal.pone.0003352openalex-snapshot
Oxygen-Independent Stabilization of Hypoxia Inducible Factor (HIF)-1 during RSV Infection
inferredcites →https://doi.org/10.1371/journal.ppat.1008319openalex-snapshot
Sirtuin 1 regulates mitochondrial function and immune homeostasis in respiratory syncytial virus infected dendritic cells
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The SWI/SNF-Related, Matrix Associated, Actin-Dependent Regulator of Chromatin A4 Core Complex Represses Respiratory Syncytial Virus-Induced Syncytia Formation and Subepithelial Myofibroblast Transition
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Role and Diagnostic Performance of Host Epigenome in Respiratory Morbidity after RSV Infection: The EPIRESVi Study
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SARS-COV-2 viroporins activate the NLRP3-inflammasome by the mitochondrial permeability transition pore
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Murine Neonatal Oxidant Lung Injury: NRF2-Dependent Predisposition to Adulthood Respiratory Viral Infection and Protection by Maternal Antioxidant
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PET Imaging with [18F]ROStrace Detects Oxidative Stress and Predicts Parkinson’s Disease Progression in Mice
inferredcites →https://doi.org/10.3390/cells12091311openalex-snapshot
Respiratory Syncytial Virus Matrix Protein Is Sufficient and Necessary to Remodel Host Mitochondria in Infection
inferredcites →https://doi.org/10.3390/cells8111417openalex-snapshot
Subversion of Host Cell Mitochondria by RSV to Favor Virus Production is Dependent on Inhibition of Mitochondrial Complex I and ROS Generation
inferredcites →https://doi.org/10.3390/v12101088openalex-snapshot
HIF-1α Modulates Core Metabolism and Virus Replication in Primary Airway Epithelial Cells Infected with Respiratory Syncytial Virus
inferredcites →https://doi.org/10.7554/elife.42448openalex-snapshot
Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production
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