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Autophagy Inhibition Promotes Bevacizumab-induced Apoptosis and Proliferation Inhibition in Colorectal Cancer Cells

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions
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Role of VEGF, CD105, and CD31 in the Prognosis of Colorectal Cancer Cases
inferredcites →https://doi.org/10.1016/j.canlet.2014.11.046openalex-snapshot
Oxamate-mediated inhibition of lactate dehydrogenase induces protective autophagy in gastric cancer cells: Involvement of the Akt–mTOR signaling pathway
inferredcites →https://doi.org/10.1016/j.critrevonc.2016.02.005openalex-snapshot
Second-line angiogenesis inhibition in metastatic colorectal cancer patients: Straightforward or overcrowded?
inferredcites →https://doi.org/10.1016/j.redox.2014.12.003openalex-snapshot
Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy
inferredcites →https://doi.org/10.1016/j.urolonc.2017.08.010openalex-snapshot
Second-line systemic therapy in metastatic renal-cell carcinoma: A review
inferredcites →https://doi.org/10.1016/j.ygyno.2008.11.030openalex-snapshot
Independent prognostic relevance of microvessel density in advanced epithelial ovarian cancer and associations between CD31, CD105, p53 status, and angiogenic marker expression: A Gynecologic Oncology Group study
inferredcites →https://doi.org/10.1038/cddis.2017.371openalex-snapshot
Administration of follicle-stimulating hormone induces autophagy via upregulation of HIF-1α in mouse granulosa cells
inferredcites →https://doi.org/10.1038/nrclinonc.2011.21openalex-snapshot
Antiangiogenic therapy: impact on invasion, disease progression, and metastasis
inferredcites →https://doi.org/10.1053/j.seminoncol.2017.07.004openalex-snapshot
Angiogenesis inhibition in the second-line treatment of metastatic colorectal cancer: A systematic review and pooled analysis
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Prognostic Value of Vascular Endothelial Growth Factor Expression in Patients with Lung Cancer: A Systematic Review with Meta-Analysis
inferredcites →https://doi.org/10.1097/ppo.0000000000000134openalex-snapshot
A Decade of Experience in Developing Preclinical Models of Advanced- or Early-Stage Spontaneous Metastasis to Study Antiangiogenic Drugs, Metronomic Chemotherapy, and the Tumor Microenvironment
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The Great Escape; the Hallmarks of Resistance to Antiangiogenic Therapy
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Global Patterns of Cancer Incidence and Mortality Rates and Trends
inferredcites →https://doi.org/10.1158/1078-0432.ccr-12-1542openalex-snapshot
Autophagy Inhibition Sensitizes Colon Cancer Cells to Antiangiogenic and Cytotoxic Therapy
inferredcites →https://doi.org/10.1158/1078-0432.ccr-15-0490openalex-snapshot
Autophagy, Metabolism, and Cancer
inferredcites →https://doi.org/10.1172/jci73941openalex-snapshot
The role for autophagy in cancer
inferredcites →https://doi.org/10.21037/tlcr.2016.08.04openalex-snapshot
Targeting angiogenesis in small cell lung cancer
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The influence of vascular endothelial growth factor-A and matrix metalloproteinase-2 and -9 in angiogenesis, metastasis, and prognosis of endometrial cancer
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Antiangiogenic Therapy in Malignant Glioma: Promise and Challenge
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Global cancer statistics, 2012
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Proportion and number of cancer cases and deaths attributable to potentially modifiable risk factors in the United States
inferredcites →https://doi.org/10.3390/cells6040037openalex-snapshot
Standard Assays for the Study of Autophagy in the Ex Vivo Retina
inferredcites →https://doi.org/10.3390/ijms18092016openalex-snapshot
Autophagy and Inflammatory Response in the Tumor Microenvironment
inferredcites →https://doi.org/10.3892/etm.2016.3190openalex-snapshot
Hypoxia induces autophagy in cardiomyocytes via a hypoxia-inducible factor 1-dependent mechanism

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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FUT2-Dependent Fucosylation of LAMP1 Promotes Apoptosis of Colorectal Cancer Cells by Regulating Autophagy-Lysosomal Pathway
inferred← citeshttps://doi.org/10.1002/ddr.21878openalex-snapshot
Astragaloside IV enhances the sensibility of lung adenocarcinoma cells to bevacizumab by inhibiting autophagy
inferred← citeshttps://doi.org/10.1002/ski2.471openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s10495-021-01687-9openalex-snapshot
Mechanism of interaction between autophagy and apoptosis in cancer
inferred← citeshttps://doi.org/10.1007/s12013-026-02161-6openalex-snapshot
IER5L Facilitates the Progression of Hormone Receptor-Positive Breast Cancer by Inhibiting HSF1 Phosphorylation in Response to Bevacizumab
inferred← citeshttps://doi.org/10.1007/s12032-023-01980-4openalex-snapshot
The critical role of circular RNAs in drug resistance in gastrointestinal cancers
inferred← citeshttps://doi.org/10.1007/s40261-026-01579-3openalex-snapshot
Repurposing Antipsychotics in Cancer Therapy: Modulation of Autophagy Mechanisms
inferred← citeshttps://doi.org/10.1016/b978-0-443-33343-9.00003-xopenalex-snapshot
Resensitization strategies toward autophagic resistance
inferred← citeshttps://doi.org/10.1016/j.bbadis.2022.166431openalex-snapshot
Autophagy and EMT in cancer and metastasis: Who controls whom?
inferred← citeshttps://doi.org/10.1016/j.bbcan.2022.188775openalex-snapshot
Anti-PD-1 combined with targeted therapy: Theory and practice in gastric and colorectal cancer
inferred← citeshttps://doi.org/10.1016/j.canlet.2023.216307openalex-snapshot
Autophagy and cancer drug resistance in dialogue: Pre-clinical and clinical evidence
inferred← citeshttps://doi.org/10.1016/j.canlet.2025.217643openalex-snapshot
FUT2-dependent fucosylation of LAMP1 promotes the apoptosis of colorectal cancer cells by regulating the autophagy-lysosomal pathway
inferred← citeshttps://doi.org/10.1016/j.ctrv.2020.102043openalex-snapshot
The role of autophagy in resistance to targeted therapies
inferred← citeshttps://doi.org/10.1016/j.cyto.2024.156674openalex-snapshot
Adaptive resistance of tumor cells to anti-vascular endothelial growth factor therapy: A reversible phenomenon
inferred← citeshttps://doi.org/10.1016/j.drup.2022.100849openalex-snapshot
New insights into antiangiogenic therapy resistance in cancer: Mechanisms and therapeutic aspects
inferred← citeshttps://doi.org/10.1016/j.envres.2023.115721openalex-snapshot
Rational targeting of autophagy in colorectal cancer therapy: From molecular interactions to pharmacological compounds
inferred← citeshttps://doi.org/10.1016/j.envres.2023.117006openalex-snapshot
Autophagy/ferroptosis in colorectal cancer: Carcinogenic view and nanoparticle-mediated cell death regulation
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2022.02.005openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.intimp.2024.111876openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112896openalex-snapshot
Antitumor effects of IOX1 combined with bevacizumab-induced apoptosis and immunity on colorectal cancer cells
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2024.109623openalex-snapshot
Cafestol inhibits colon cancer cell proliferation and tumor growth in xenograft mice by activating LKB1/AMPK/ULK1-dependent autophagy
inferred← citeshttps://doi.org/10.1016/j.lfs.2024.123121openalex-snapshot
Navigating therapeutic prospects by modulating autophagy in colorectal cancer
inferred← citeshttps://doi.org/10.1016/j.semcancer.2019.08.031openalex-snapshot
Autophagy as a mechanism for anti-angiogenic therapy resistance
inferred← citeshttps://doi.org/10.1016/j.tiv.2023.105631openalex-snapshot
Tetrazolium–based colorimetric assays underestimat the direct antitumor effects of anti-VEGF agent bevacizumab
inferred← citeshttps://doi.org/10.1016/j.tranon.2020.100871openalex-snapshot
The interaction mechanism between autophagy and apoptosis in colon cancer
inferred← citeshttps://doi.org/10.1080/00365521.2022.2088247openalex-snapshot
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inferred← citeshttps://doi.org/10.1080/15476286.2026.2670829openalex-snapshot
Bevacizumab induces apoptosis in glioblastoma cells by upregulating miR-4695-5p to inhibit PKMYT1
inferred← citeshttps://doi.org/10.1111/jgh.15937openalex-snapshot
The emerging era of personalized medicine in advanced colorectal cancer
inferred← citeshttps://doi.org/10.1134/s1607672924600283openalex-snapshot
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inferred← citeshttps://doi.org/10.1177/10732748251384365openalex-snapshot
Unveiling the Paradoxical Nature of Autophagy in Cancer Cell Fate
inferred← citeshttps://doi.org/10.1186/s12935-019-0897-8openalex-snapshot
MiR-369-3p participates in endometrioid adenocarcinoma via the regulation of autophagy
inferred← citeshttps://doi.org/10.1186/s43556-026-00430-7openalex-snapshot
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inferred← citeshttps://doi.org/10.21037/jgo-21-31openalex-snapshot
Colorectal cancer in pregnancy: a case report and literature review
inferred← citeshttps://doi.org/10.2139/ssrn.5074878openalex-snapshot
Fut2-Dependent Fucosylation of Lamp1 Promotes the Apoptosis of Colorectal Cancer Cells by Regulating the Autophagy-Lysosomal Pathway
inferred← citeshttps://doi.org/10.2174/1389557519666190730110600openalex-snapshot
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Molecular Mechanisms Underlying Autophagy-Mediated Treatment Resistance in Cancer
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Autophagy in Cancer Therapy—Molecular Mechanisms and Current Clinical Advances
inferred← citeshttps://doi.org/10.3390/cancers13225622openalex-snapshot
Understanding the Role of Autophagy in Cancer Formation and Progression Is a Real Opportunity to Treat and Cure Human Cancers
inferred← citeshttps://doi.org/10.3390/cancers13246152openalex-snapshot
Emerging Role of Autophagy in the Development and Progression of Oral Squamous Cell Carcinoma
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Cancer Cells Promote Phenotypic Alterations in Hepatocytes at the Edge of Cancer Cell Nests to Facilitate Vessel Co-Option Establishment in Colorectal Cancer Liver Metastases
inferred← citeshttps://doi.org/10.3390/cancers16234060openalex-snapshot
Interfering Nuclear Protein Laminb1 Induces DNA Damage and Reduces Vemurafenib Resistance in Melanoma Cells In Vitro
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Relationship between VEGF Family Members, Their Receptors and Cell Death in the Neoplastic Transformation of Colorectal Cancer
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T Cells in Colorectal Cancer: Unravelling the Function of Different T Cell Subsets in the Tumor Microenvironment
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From Crypts to Cancer: A Holistic Perspective on Colorectal Carcinogenesis and Therapeutic Strategies
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Hydroxychloroquine enhances the antitumor effects of BC001 in gastric cancer
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INVESTIGATION OF ELLAGIC ACID IN HUMAN COLON CANCER CELLS
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