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Biological roles and clinical significance of estrogen and androgen receptors in head and neck cancers

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Growth Effects of Tamoxifen and Estradiol on Laryngeal Carcinoma Cell Lines
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Definitive treatment of androgen receptor–positive salivary duct carcinoma with androgen deprivation therapy and external beam radiotherapy
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Clinical activity of androgen deprivation therapy in patients with metastatic/relapsed androgen receptor–positive salivary gland cancers
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Androgen deprivation therapy for androgen receptor‐positive advanced salivary duct carcinoma: A nationwide case series of 35 patients in The Netherlands
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The tumor immune contexture of salivary duct carcinoma
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Expression of estrogen receptor alpha is associated with pathogenesis and prognosis of human papillomavirus‐positive oropharyngeal cancer
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Prediction of clinical benefit from androgen deprivation therapy in salivary duct carcinoma patients
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Immunohistochemical study of estrogen receptor and estradiol on papillary thyroid carcinoma in young patients
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Targeting fatty acid synthase with ASC‐J9 suppresses proliferation and invasion of prostate cancer cells
inferredcites →https://doi.org/10.1007/s00066-013-0389-zopenalex-snapshot
Androgen receptor expression
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Expression of hormone receptors in oropharyngeal squamous cell carcinoma
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Tamoxifen for salivary gland adenoid cystic carcinoma: report of two cases
inferredcites →https://doi.org/10.1007/s10552-019-01185-zopenalex-snapshot
Treatment trends in head and neck cancer: Surveillance, Epidemiology, and End Results (SEER) Patterns of Care analysis
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Androgen receptor signaling in prostate cancer
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Expression of PTEN, Androgen Receptor, HER2/neu, Cytokeratin 5/6, Estrogen Receptor-Beta, HMGA2, and PLAG1 in Salivary Duct Carcinoma
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17Beta-Estradiol Promotes Aggressive Laryngeal Cancer Through Membrane-Associated Estrogen Receptor-Alpha 36
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Pioneer of prostate cancer: past, present and the future of FOXA1
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Estrogen receptor signaling mechanisms
inferredcites →https://doi.org/10.1016/j.coms.2018.06.001openalex-snapshot
Epidemiology and Demographics of the Head and Neck Cancer Population
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Predicting response to hormonal therapy and survival in men with hormone sensitive metastatic prostate cancer
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Systemic therapy in the management of recurrent or metastatic salivary duct carcinoma: A systematic review
inferredcites →https://doi.org/10.1016/j.ebiom.2018.12.050openalex-snapshot
Preclinical study using androgen receptor (AR) degradation enhancer to increase radiotherapy efficacy via targeting radiation-increased AR to better suppress prostate cancer progression
inferredcites →https://doi.org/10.1016/j.ejmech.2020.112501openalex-snapshot
An orally available inverse agonist of estrogen-related receptor gamma showed expanded efficacy for the radioiodine therapy of poorly differentiated thyroid cancer
inferredcites →https://doi.org/10.1016/j.jsbmb.2020.105671openalex-snapshot
Characterization of a membrane-associated estrogen receptor in breast cancer cells and its contribution to hormone therapy resistance using a novel selective ligand
inferredcites →https://doi.org/10.1016/j.otohns.2009.03.003openalex-snapshot
Estrogen receptor overexpression in malignant minor salivary gland tumors of the sinonasal tract
inferredcites →https://doi.org/10.1016/j.semcancer.2020.12.007openalex-snapshot
Nuclear receptors: Lipid and hormone sensors with essential roles in the control of cancer development
inferredcites →https://doi.org/10.1016/j.soc.2015.03.001openalex-snapshot
Epidemiology of Head and Neck Cancer
inferredcites →https://doi.org/10.1016/j.steroids.2017.11.012openalex-snapshot
Estradiol receptor profile and estrogen responsiveness in laryngeal cancer and clinical outcomes
inferredcites →https://doi.org/10.1016/j.steroids.2019.108498openalex-snapshot
Estrogen signaling and estrogen receptors as prognostic indicators in laryngeal cancer
inferredcites →https://doi.org/10.1016/j.tice.2019.02.007openalex-snapshot
The prognostic value of sex hormone receptors expression in laryngeal carcinoma
inferredcites →https://doi.org/10.1016/s1470-2045(21)00076-0openalex-snapshot
Chemotherapy and radiotherapy in locally advanced head and neck cancer: an individual patient data network meta-analysis
inferredcites →https://doi.org/10.1038/cr.2018.15openalex-snapshot
Tamoxifen enhances stemness and promotes metastasis of ERα36+ breast cancer by upregulating ALDH1A1 in cancer cells
inferredcites →https://doi.org/10.1038/emboj.2011.340openalex-snapshot
FOXA1: master of steroid receptor function in cancer
inferredcites →https://doi.org/10.1038/s41591-020-01168-7openalex-snapshot
The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer
inferredcites →https://doi.org/10.1038/s41598-020-60675-2openalex-snapshot
Loss of Estrogen Receptors is Associated with Increased Tumor Aggression in Laryngeal Squamous Cell Carcinoma
inferredcites →https://doi.org/10.1056/nejmoa1905287openalex-snapshot
Gemcitabine and Cisplatin Induction Chemotherapy in Nasopharyngeal Carcinoma
inferredcites →https://doi.org/10.1073/pnas.1808834116openalex-snapshot
Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer
inferredcites →https://doi.org/10.1093/annonc/mdg331openalex-snapshot
A complete remission with androgen-deprivation therapy in a recurrent androgen receptor-expressing adenocarcinoma of the parotid gland
inferredcites →https://doi.org/10.1093/annonc/mdx771openalex-snapshot
A prospective phase II study of combined androgen blockade in patients with androgen receptor-positive metastatic or locally advanced unresectable salivary gland carcinoma
inferredcites →https://doi.org/10.1093/carcin/23.10.1569openalex-snapshot
Tamoxifen inhibits the growth of head and neck cancer cells and sensitizes these cells to cisplatin induced-apoptosis: role of TGF-beta1
inferredcites →https://doi.org/10.1093/jnci/djy224openalex-snapshot
Association of Estrogen Receptor Alpha Expression With Survival in Oropharyngeal Cancer Following Chemoradiation Therapy
inferredcites →https://doi.org/10.1093/nar/gkaa178openalex-snapshot
Differential modulation of the androgen receptor for prostate cancer therapy depends on the DNA response element
inferredcites →https://doi.org/10.1093/nar/gkm198openalex-snapshot
A promoting role of androgen receptor in androgen-sensitive and -insensitive prostate cancer cells
inferredcites →https://doi.org/10.1111/j.1349-7006.2007.00437.xopenalex-snapshot
Critical role of estrogen receptor on anoikis and invasion of squamous cell carcinoma
inferredcites →https://doi.org/10.1111/j.1440-1827.2008.02231.xopenalex-snapshot
Aggressive invasive micropapillary salivary duct carcinoma of the parotid gland
inferredcites →https://doi.org/10.1111/jop.12741openalex-snapshot
Androgen receptor in salivary gland carcinoma: A review of an old marker as a possible new target
inferredcites →https://doi.org/10.1111/odi.12272openalex-snapshot
The oncogenic role of androgen receptors in promoting the growth of oral squamous cell carcinoma cells
inferredcites →https://doi.org/10.1124/pr.114.009712openalex-snapshot
International Union of Basic and Clinical Pharmacology. XCVII. G Protein–Coupled Estrogen Receptor and Its Pharmacologic Modulators
inferredcites →https://doi.org/10.1126/scitranslmed.aaa4442openalex-snapshot
PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor–positive breast cancer
inferredcites →https://doi.org/10.1152/physrev.00024.2016openalex-snapshot
Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications
inferredcites →https://doi.org/10.1158/1078-0432.ccr-07-1373openalex-snapshot
Membrane-Associated Estrogen Receptor Signaling Pathways in Human Cancers
inferredcites →https://doi.org/10.1158/1078-0432.ccr-09-0862openalex-snapshot
Cross-Talk between Estrogen Receptor and Epidermal Growth Factor Receptor in Head and Neck Squamous Cell Carcinoma
inferredcites →https://doi.org/10.1158/1078-0432.ccr-19-1603openalex-snapshot
Reciprocal and Autonomous Glucocorticoid and Androgen Receptor Activation in Salivary Duct Carcinoma
inferredcites →https://doi.org/10.1158/1078-0432.ccr-20-0557openalex-snapshot
Integrative Analysis of miRNAs Identifies Clinically Relevant Epithelial and Stromal Subtypes of Head and Neck Squamous Cell Carcinoma
inferredcites →https://doi.org/10.1158/1940-6207.capr-10-0133openalex-snapshot
Estrogen and Cytochrome P450 1B1 Contribute to Both Early- and Late-Stage Head and Neck Carcinogenesis
inferredcites →https://doi.org/10.1158/2159-8290.cd-11-0192openalex-snapshot
ER and PI3K Independently Modulate Endocrine Resistance in ER-Positive Breast Cancer
inferredcites →https://doi.org/10.1177/0194599819897265openalex-snapshot
Global Burden of Head and Neck Cancer: Economic Consequences, Health, and the Role of Surgery
inferredcites →https://doi.org/10.1177/10668969211001952openalex-snapshot
Parotid Salivary Duct Carcinoma With a Prominent Squamous Component: Immunohistochemical Profile, Diagnostic Pitfalls, and Therapeutic Implications
inferredcites →https://doi.org/10.1177/10732748211041236openalex-snapshot
Epidemiological Analysis of 1234 Cases of Laryngeal Cancer in Shanxi Province, China
inferredcites →https://doi.org/10.1186/1471-2407-14-383openalex-snapshot
Differential expression patterns and clinical significance of estrogen receptor-α and β in papillary thyroid carcinoma
inferredcites →https://doi.org/10.1186/s12885-019-6306-9openalex-snapshot
EZH2 upregulation by ERα induces proliferation and migration of papillary thyroid carcinoma
inferredcites →https://doi.org/10.1200/jco.2010.32.8351openalex-snapshot
Androgen Receptor–Positive Salivary Duct Carcinoma: A Disease Entity With Promising New Treatment Options
inferredcites →https://doi.org/10.1210/jc.2014-3257openalex-snapshot
Estrogen Receptor α Induces Prosurvival Autophagy in Papillary Thyroid Cancer via Stimulating Reactive Oxygen Species and Extracellular Signal Regulated Kinases
inferredcites →https://doi.org/10.1210/jc.86.3.1072openalex-snapshot
Estrogen Promotes Growth of Human Thyroid Tumor Cells by Different Molecular Mechanisms
inferredcites →https://doi.org/10.1210/jcem.86.3.7283openalex-snapshot
Estrogen Promotes Growth of Human Thyroid Tumor Cells by Different Molecular Mechanisms1
inferredcites →https://doi.org/10.12659/ajcr.925181openalex-snapshot
Combination Chemohormonal Therapy in Metastatic Salivary Duct Carcinoma
inferredcites →https://doi.org/10.1288/00005537-199409000-00013openalex-snapshot
Juvenile nasopharyngeal fibroma: Androgen receptors and their significance for tumor growth
inferredcites →https://doi.org/10.1309/rvtp-1g0q-727w-juqdopenalex-snapshot
Expression of Androgen, Estrogen, and Progesterone Receptors in Salivary Gland Tumors: Frequent Expression of Androgen Receptor in a Subset of Malignant Salivary Gland Tumors
inferredcites →https://doi.org/10.13201/j.issn.1001-1781.2018.03.008openalex-snapshot
[The expression and clinical progression of androgen, estrogen and prolactin receptor in laryngeal squamous cell carcinoma].
inferredcites →https://doi.org/10.1371/journal.pone.0042456openalex-snapshot
FOXA1 Promotes Tumor Progression in Prostate Cancer via the Insulin-Like Growth Factor Binding Protein 3 Pathway
inferredcites →https://doi.org/10.1371/journal.pone.0223154openalex-snapshot
Early mortality after diagnosis of cancer of the head and neck – A population-based nationwide study
inferredcites →https://doi.org/10.1530/eje-15-0054openalex-snapshot
Impact of estrogen and progesterone receptor expression on the clinical and molecular features of papillary thyroid cancer
inferredcites →https://doi.org/10.1530/erc-11-0389openalex-snapshot
Expression of estrogen and androgen receptors in differentiated thyroid cancer: an additional criterion to assess the patient's risk
inferredcites →https://doi.org/10.1530/erc-14-0053openalex-snapshot
Estrogen and its role in thyroid cancer
inferredcites →https://doi.org/10.1530/erc-14-0102openalex-snapshot
Regulation of estrogen receptor α function in oral squamous cell carcinoma cells by FAK signaling
inferredcites →https://doi.org/10.1677/jme-08-0103openalex-snapshot
Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways
inferredcites →https://doi.org/10.1677/joe-06-0193openalex-snapshot
Expression and role of estrogen receptor α and β in medullary thyroid carcinoma: different roles in cancer growth and apoptosis
inferredcites →https://doi.org/10.19813/j.cnki.weishengyanjiu.2020.05.015openalex-snapshot
[Roles of G protein-coupled receptor 30 in the effects of genistein on apoptosis and cell cycle in human thyroid squamous cells SW579].
inferredcites →https://doi.org/10.21101/cejph.a5565openalex-snapshot
Environmental and behavioural head and neck cancer risk factors
inferredcites →https://doi.org/10.2147/ott.s200718openalex-snapshot
Androgen receptor promotes oral squamous cell carcinoma cell migration by increasing EGFR phosphorylation
inferredcites →https://doi.org/10.2174/138920206779315737openalex-snapshot
Estrogen Signaling Multiple Pathways to Impact Gene Transcription
inferredcites →https://doi.org/10.21873/anticanres.11196openalex-snapshot
Blockade of Androgen-induced Malignant Phenotypes by Flutamide Administration in Human Salivary Duct Carcinoma Cells
inferredcites →https://doi.org/10.3109/00016357.2013.775335openalex-snapshot
Oestrogens and androgen receptors in oral squamous cell carcinoma
inferredcites →https://doi.org/10.3322/caac.21551openalex-snapshot
Cancer statistics, 2019
inferredcites →https://doi.org/10.3322/caac.21590openalex-snapshot
Cancer statistics, 2020
inferredcites →https://doi.org/10.3389/fonc.2019.00701openalex-snapshot
First Line Androgen Deprivation Therapy vs. Chemotherapy for Patients With Androgen Receptor Positive Recurrent or Metastatic Salivary Gland Carcinoma—A Retrospective Study
inferredcites →https://doi.org/10.3389/fonc.2021.759724openalex-snapshot
Patient-Reported Outcomes-Guided Adaptive Radiation Therapy for Head and Neck Cancer
inferredcites →https://doi.org/10.3390/biology10101011openalex-snapshot
Tegafur-Uracil versus 5-Fluorouracil in Combination with Cisplatin and Cetuximab in Elderly Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Propensity Score Matching Analysis
inferredcites →https://doi.org/10.3390/cancers9020017openalex-snapshot
Androgen Receptor Signaling in Salivary Gland Cancer
inferredcites →https://doi.org/10.3390/cancers9020020openalex-snapshot
Androgen Receptor Signaling in Bladder Cancer
inferredcites →https://doi.org/10.3390/ijms19020399openalex-snapshot
Sex Hormone Receptors in Benign and Malignant Salivary Gland Tumors: Prognostic and Predictive Role
inferredcites →https://doi.org/10.3390/ijms19030713openalex-snapshot
Estrogen Receptor Signaling in Radiotherapy: From Molecular Mechanisms to Clinical Studies
inferredcites →https://doi.org/10.3390/ijms19092591openalex-snapshot
Molecular Pathways of Estrogen Receptor Action
inferredcites →https://doi.org/10.3857/roj.2020.00213openalex-snapshot
Late side effects of radiation treatment for head and neck cancer
inferredcites →https://doi.org/10.3892/ijo.30.1.155openalex-snapshot
Molecular identification, expression and prognostic role of estrogen- and progesterone receptors in head and neck cancer
inferredcites →https://doi.org/10.3892/ijo_00000588openalex-snapshot
Estradiol-induced proliferation of papillary and follicular thyroid cancer cells is mediated by estrogen receptors α and β
inferredcites →https://doi.org/10.3892/ol.2016.5142openalex-snapshot
The prognostic significance of estrogen receptor β in head and neck squamous cell carcinoma
inferredcites →https://doi.org/10.3892/or_00000537openalex-snapshot
Estrogen receptor-β expression in human laryngeal carcinoma: correlation with the expression of epithelial-mesenchymal transition specific biomarkers
inferredcites →https://doi.org/10.4132/jptm.2020.07.19openalex-snapshot
Primary squamous cell carcinoma of the salivary gland: immunohistochemical analysis and comparison with metastatic squamous cell carcinoma
inferredcites →https://doi.org/10.4161/cbt.28410openalex-snapshot
Activity of abiraterone in rechallenging two AR-expressing salivary gland adenocarcinomas, resistant to androgen-deprivation therapy
inferredcites →https://doi.org/10.4317/medoral.16.e330openalex-snapshot
An immunohistochemical study of androgen receptor in carcinoma arising in pleomorphic salivary adenoma
inferredcites →https://doi.org/10.7150/jca.34016openalex-snapshot
Effect of HPV Infection on the Occurrence and Development of Laryngeal Cancer: A Review

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1001/jamaoto.2023.4739openalex-snapshot
Exogenous Estrogen in the Development of Head and Neck Cancer
inferred← citeshttps://doi.org/10.1007/s10006-025-01494-5openalex-snapshot
Tongue cancer in pregnancy: challenges and outcomes. A case series and review of the literature
inferred← citeshttps://doi.org/10.1007/s10585-025-10363-0openalex-snapshot
Prognostic influence of chronic inflammation in patients with head and neck cancer based on sex differences
inferred← citeshttps://doi.org/10.1007/s11030-025-11142-5openalex-snapshot
Integrating network pharmacology, molecular docking, and bioinformatics to explore the mechanism of sparganii rhizoma in the treatment of laryngeal cancer
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Extraction optimization of bioactive compounds from Vitex negundo through RSM: GC–MS, FTIR, in silico analysis, and antibacterial activity
inferred← citeshttps://doi.org/10.1016/j.amjoto.2023.104195openalex-snapshot
Does sex influence the prognosis of laryngeal cancer? A systematic review and a meta-analysis
inferred← citeshttps://doi.org/10.1016/j.crbiot.2024.100253openalex-snapshot
Identification of a prognostic model based on cuproptosis and ferroptosis-related genes in patients with head and neck squamous cell carcinoma
inferred← citeshttps://doi.org/10.1016/j.mrgentox.2025.503858openalex-snapshot
AI/ML modeling to enhance the capability of in vitro and in vivo tests in predicting human carcinogenicity
inferred← citeshttps://doi.org/10.1371/journal.pone.0327619openalex-snapshot
Graph attention networks for predicting drug-gene association of glucocorticoid in oral squamous cell carcinoma: A comparison with GraphSAGE
inferred← citeshttps://doi.org/10.2478/aite-2026-0005openalex-snapshot
Methylparaben Modulates the Relationship Between Autophagy and Apoptosis in Head and Neck Squamous Cell Carcinoma Lines
inferred← citeshttps://doi.org/10.3389/fgene.2022.1084206openalex-snapshot
An original cuproptosis-related genes signature effectively influences the prognosis and immune status of head and neck squamous cell carcinoma
inferred← citeshttps://doi.org/10.3389/fonc.2023.1106249openalex-snapshot
Identification of a seven-lncRNAs panel that serves as a prognosis predictor and contributes to the malignant progression of laryngeal squamous cell carcinoma
inferred← citeshttps://doi.org/10.3390/cancers16071352openalex-snapshot
Association between Head and Neck Cancer and Increased Risk of Ischemic Heart Disease: A Retrospective Cohort Study Using National Population Data
inferred← citeshttps://doi.org/10.3390/cancers16081575openalex-snapshot
The Role of Estrogen and Estrogen Receptors in Head and Neck Tumors
inferred← citeshttps://doi.org/10.3390/cancers16091635openalex-snapshot
Laryngeal Cancer Cells Metabolize 25-Hydroxyvitamin D3 and Respond to 24R,25-dihydroxyvitamin D3 via a Mechanism Dependent on Estrogen Receptor Levels
inferred← citeshttps://doi.org/10.3390/cancers17213414openalex-snapshot
Testosterone and Androgen Receptor in Cancers with Significant Sex Dimorphism in Incidence Rates and Survival
inferred← citeshttps://doi.org/10.3390/cells12030363openalex-snapshot
Taspase1 Facilitates Topoisomerase IIβ-Mediated DNA Double-Strand Breaks Driving Estrogen-Induced Transcription
inferred← citeshttps://doi.org/10.3390/ph16050754openalex-snapshot
RadioLigand Therapy with [177Lu]Lu-PSMA-617 for Salivary Gland Cancers: Literature Review and First Compassionate Use in France
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