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Non‐Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co‐Delivery of Cas9 mRNA and sgRNA

https://doi.org/10.1002/ange.201610209
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Bioinspired Alkenyl Amino Alcohol Ionizable Lipid Materials for Highly Potent In Vivo mRNA Delivery
inferredcites →https://doi.org/10.1002/ange.201203263openalex-snapshot
Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo**
inferredcites →https://doi.org/10.1002/ange.201506030openalex-snapshot
Self‐Assembled DNA Nanoclews for the Efficient Delivery of CRISPR–Cas9 for Genome Editing
inferredcites →https://doi.org/10.1002/ange.201603648openalex-snapshot
A Single Methylene Group in Oligoalkylamine‐Based Cationic Polymers and Lipids Promotes Enhanced mRNA Delivery
inferredcites →https://doi.org/10.1002/ange.201608450openalex-snapshot
Polymer–Lipid Nanoparticles for Systemic Delivery of mRNA to the Lungs
inferredcites →https://doi.org/10.1002/anie.201203263openalex-snapshot
Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo**
inferredcites →https://doi.org/10.1002/anie.201506030openalex-snapshot
Self‐Assembled DNA Nanoclews for the Efficient Delivery of CRISPR–Cas9 for Genome Editing
inferredcites →https://doi.org/10.1002/anie.201603648openalex-snapshot
A Single Methylene Group in Oligoalkylamine‐Based Cationic Polymers and Lipids Promotes Enhanced mRNA Delivery
inferredcites →https://doi.org/10.1002/anie.201608450openalex-snapshot
Polymer–Lipid Nanoparticles for Systemic Delivery of mRNA to the Lungs
inferredcites →https://doi.org/10.1007/978-1-60761-753-2_15openalex-snapshot
A Rapid and General Assay for Monitoring Endogenous Gene Modification
inferredcites →https://doi.org/10.1016/j.cell.2014.09.014openalex-snapshot
CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling
inferredcites →https://doi.org/10.1016/j.cell.2015.02.038openalex-snapshot
Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis
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Designer lipids for drug delivery: From heads to tails
inferredcites →https://doi.org/10.1021/acs.nanolett.5b02428openalex-snapshot
Poly(glycoamidoamine) Brushes Formulated Nanomaterials for Systemic siRNA and mRNA Delivery in Vivo
inferredcites →https://doi.org/10.1021/acs.nanolett.5b02497openalex-snapshot
Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs
inferredcites →https://doi.org/10.1021/jacs.5b03429openalex-snapshot
Rapid Synthesis of a Lipocationic Polyester Library via Ring-Opening Polymerization of Functional Valerolactones for Efficacious siRNA Delivery
inferredcites →https://doi.org/10.1021/jp3088786openalex-snapshot
Correction to “Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core”
inferredcites →https://doi.org/10.1021/nn301922xopenalex-snapshot
In Vitro–In Vivo Translation of Lipid Nanoparticles for Hepatocellular siRNA Delivery
inferredcites →https://doi.org/10.1038/nature13589openalex-snapshot
CRISPR-mediated direct mutation of cancer genes in the mouse liver
inferredcites →https://doi.org/10.1038/nature13906openalex-snapshot
Rapid modelling of cooperating genetic events in cancer through somatic genome editing
inferredcites →https://doi.org/10.1038/nbt.1602openalex-snapshot
Rational design of cationic lipids for siRNA delivery
inferredcites →https://doi.org/10.1038/nbt.2612openalex-snapshot
Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape
inferredcites →https://doi.org/10.1038/nbt.2842openalex-snapshot
CRISPR-Cas systems for editing, regulating and targeting genomes
inferredcites →https://doi.org/10.1038/nbt.2884openalex-snapshot
Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype
inferredcites →https://doi.org/10.1038/nbt.3081openalex-snapshot
Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo
inferredcites →https://doi.org/10.1038/nbt.3298openalex-snapshot
Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown
inferredcites →https://doi.org/10.1038/nbt1402openalex-snapshot
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
inferredcites →https://doi.org/10.1038/nmat3765openalex-snapshot
Delivery materials for siRNA therapeutics
inferredcites →https://doi.org/10.1038/nprot.2013.143openalex-snapshot
Genome engineering using the CRISPR-Cas9 system
inferredcites →https://doi.org/10.1038/nrc3950openalex-snapshot
Applications of the CRISPR–Cas9 system in cancer biology
inferredcites →https://doi.org/10.1039/c2cc31710aopenalex-snapshot
Synthesis and characterization of novel zwitterionic lipids with pH-responsive biophysical properties
inferredcites →https://doi.org/10.1039/c4cc02866jopenalex-snapshot
Sulfated quaternary amine lipids: a new class of inverse charge zwitterlipids
inferredcites →https://doi.org/10.1073/pnas.0910603106openalex-snapshot
Lipid-like materials for low-dose, in vivo gene silencing
inferredcites →https://doi.org/10.1073/pnas.1520244113openalex-snapshot
Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles
inferredcites →https://doi.org/10.1073/pnas.1520756113openalex-snapshot
Modular degradable dendrimers enable small RNAs to extend survival in an aggressive liver cancer model
inferredcites →https://doi.org/10.1073/pnas.1606886113openalex-snapshot
Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells
inferredcites →https://doi.org/10.1126/sciadv.1500454openalex-snapshot
CRISPR-Cas9 delivery to hard-to-transfect cells via membrane deformation
inferredcites →https://doi.org/10.1126/science.1225829openalex-snapshot
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
inferredcites →https://doi.org/10.1126/science.1231143openalex-snapshot
Multiplex Genome Engineering Using CRISPR/Cas Systems
inferredcites →https://doi.org/10.1126/science.1232033openalex-snapshot
RNA-Guided Human Genome Engineering via Cas9
inferredcites →https://doi.org/10.1126/science.aad5143openalex-snapshot
In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy
inferredcites →https://doi.org/10.1126/science.aad5177openalex-snapshot
In vivo gene editing in dystrophic mouse muscle and muscle stem cells
inferredcites →https://doi.org/10.1126/science.aad5725openalex-snapshot
Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy
inferredcites →https://doi.org/10.1186/s13059-015-0680-7openalex-snapshot
A versatile reporter system for CRISPR-mediated chromosomal rearrangements

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Delivery of Rna Drugs: Beyond the Liver, More than Vaccine
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Nanotechnology in Gene Editing: Pioneering CRISPR‐Cas Delivery Systems to Tackle Antibiotic Resistance
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A Systematic Study of Unsaturation in Lipid Nanoparticles Leads to Improved mRNA Transfection In Vivo
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Hypoxia‐Responsive Gene Editing to Reduce Tumor Thermal Tolerance for Mild‐Photothermal Therapy
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Thermo‐triggered Release of CRISPR‐Cas9 System by Lipid‐Encapsulated Gold Nanoparticles for Tumor Therapy
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Customizable Lipid Nanoparticle Materials for the Delivery of siRNAs and mRNAs
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Triple‐Targeting Delivery of CRISPR/Cas9 To Reduce the Risk of Cardiovascular Diseases
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Spatiotemporal Delivery of CRISPR/Cas9 Genome Editing Machinery Using Stimuli‐Responsive Vehicles
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A Systematic Study of Unsaturation in Lipid Nanoparticles Leads to Improved mRNA Transfection In Vivo
inferred← citeshttps://doi.org/10.1002/anie.202107036openalex-snapshot
Hypoxia‐Responsive Gene Editing to Reduce Tumor Thermal Tolerance for Mild‐Photothermal Therapy
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Dibenzocyclooctyne‐Branched Primer Assembled Gene Nanovector and Its Potential Applications in Genome Editing
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The mixing method used to formulate lipid nanoparticles affects mRNA delivery efficacy and organ tropism
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Polyether/Polythioether Synthesis via Ring-Opening Polymerization of Epoxides and Episulfides Catalyzed by Alkali Metal Carboxylates
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Dual-Regulated Functionalized Liposome–Nanoparticle Hybrids Loaded with Dexamethasone/TGFβ1-siRNA for Targeted Therapy of Glomerulonephritis
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