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Intracellular antibody‐mediated immunity and the role of TRIM21

https://doi.org/10.1002/bies.201100093

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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TRIM21 is an IgG receptor that is structurally, thermodynamically, and kinetically conserved

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Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)

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Fas-associated Death Domain (FADD) and the E3 Ubiquitin-Protein Ligase TRIM21 Interact to Negatively Regulate Virus-induced Interferon Production

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Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block

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Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23–Th17 pathway

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