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Integrated continuous bioprocessing: Economic, operational, and environmental feasibility for clinical and commercial antibody manufacture
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Process Economic Drivers in Industrial Monoclonal Antibody Manufacture
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Periodic counter‐current chromatography – design and operational considerations for integrated and continuous purification of proteins
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A computer‐aided approach to compare the production economics of fed‐batch and perfusion culture under uncertainty
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Weak partitioning chromatography for anion exchange purification of monoclonal antibodies
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Integrated continuous production of recombinant therapeutic proteins
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Fed‐batch and perfusion culture processes: Economic, environmental, and operational feasibility under uncertainty
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The future of industrial bioprocessing: Batch or continuous?
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State‐of‐the‐art in downstream processing of monoclonal antibodies: Process trends in design and validation
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Established Bioprocesses for Producing Antibodies as a Basis for Future Planning
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Technology trends in antibody purification
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Improving affinity chromatography resin efficiency using semi-continuous chromatography
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Optimising the design and operation of semi-continuous affinity chromatography for clinical and commercial manufacture
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Modelling biopharmaceutical manufacture: Design and implementation of SimBiopharma
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A multi-criteria decision-making framework for the selection of strategies for acquiring biopharmaceutical manufacturing capacity
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The cost of drug development: A systematic review
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Application of a Decision-Support Tool to Assess Pooling Strategies in Perfusion Culture Processes under Uncertainty
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Combining Multiple Quantitative and Qualitative Goals When Assessing Biomanufacturing Strategies under Uncertainty
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Very Large Scale Monoclonal Antibody Purification: The Case for Conventional Unit Operations
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Trends in Risks Associated With New Drug Development: Success Rates for Investigational Drugs
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The impact of continuous multicolumn chromatography on biomanufacturing efficiency
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Industrialization of mAb production technology: The bioprocessing industry at a crossroads
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Preclinical development of monoclonal antibodies
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Continuous bioprocessing: The real thing this time?
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Shift to high‐intensity, low‐volume perfusion cell culture enabling a continuous, integrated bioprocess
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Reduction of medium consumption in perfusion mammalian cell cultures using a perfusion rate equivalent concentrated nutrient feed
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Process analytical technique ( PAT ) miniaturization for monoclonal antibody aggregate detection in continuous downstream processing
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Calcium-dependent magnetic separation: A novel approach for the integrated processing of high-quality mAbs
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The Current Scientific and Regulatory Landscape in Advancing Integrated Continuous Biopharmaceutical Manufacturing
inferred← citeshttps://doi.org/10.1016/j.tibtech.2020.07.004openalex-snapshot
Process Analytical Technologies and Data Analytics for the Manufacture of Monoclonal Antibodies
inferred← citeshttps://doi.org/10.1016/j.toxcx.2020.100039openalex-snapshot
Toxinology provides multidirectional and multidimensional opportunities: A personal perspective
inferred← citeshttps://doi.org/10.1016/j.toxicon.2026.109070openalex-snapshot
Design and techno-economic assessment of an industrial-scale polyvalent clostridial vaccine production process
inferred← citeshttps://doi.org/10.1017/9781108847209openalex-snapshot
Perfusion Cell Culture Processes for Biopharmaceuticals
inferred← citeshttps://doi.org/10.1017/9781108847209.001openalex-snapshot
Perfusion Mammalian Cell Culture for Recombinant Protein Manufacturing
inferred← citeshttps://doi.org/10.1017/9781108847209.002openalex-snapshot
Perfusion Bioreactors:The Set-Up and Process Characterisation
inferred← citeshttps://doi.org/10.1017/9781108847209.003openalex-snapshot
Scale-Down Models and Sensors for Process Development
inferred← citeshttps://doi.org/10.1017/9781108847209.004openalex-snapshot
Design and Optimisation of Mammalian Cell Perfusion Cultures
inferred← citeshttps://doi.org/10.1017/9781108847209.005openalex-snapshot
Clinical- and Commercial-Scale Reactors
inferred← citeshttps://doi.org/10.1017/9781108847209.006openalex-snapshot
Mechanistic and Statistical Modelling of Bioprocesses
inferred← citeshttps://doi.org/10.1021/acs.analchem.1c05396openalex-snapshot
Integrated Process Analytical Platform for Automated Monitoring of Monoclonal Antibody N-Linked Glycosylation
inferred← citeshttps://doi.org/10.1021/acs.analchem.7b02228openalex-snapshot
On-Line Ion Exchange Liquid Chromatography as a Process Analytical Technology for Monoclonal Antibody Characterization in Continuous Bioprocessing
inferred← citeshttps://doi.org/10.1021/acs.bioconjchem.5c00599openalex-snapshot
Continuous Processing for Manufacturing of Antibody–Drug Conjugates (ADCs)
inferred← citeshttps://doi.org/10.1021/acs.iecr.8b04717openalex-snapshot
Comparison between Batch and Continuous Monoclonal Antibody Production and Economic Analysis
inferred← citeshttps://doi.org/10.1038/s41598-026-64638-xopenalex-snapshot
Development of a chemometric platform for mid-infrared fermentation monitoring
inferred← citeshttps://doi.org/10.1080/19420862.2020.1754999openalex-snapshot
Benchmarking biopharmaceutical process development and manufacturing cost contributions to R&D
inferred← citeshttps://doi.org/10.1080/19420862.2021.1903664openalex-snapshot
Developments and opportunities in continuous biopharmaceutical manufacturing
inferred← citeshttps://doi.org/10.1080/19420862.2025.2451789openalex-snapshot
Cost and supply considerations for antibody therapeutics
inferred← citeshttps://doi.org/10.1080/19420862.2026.2706886openalex-snapshot
Optimization strategies for monoclonal antibody production: advances in simulation and artificial intelligence in bioprocessing
inferred← citeshttps://doi.org/10.1088/1742-6596/2049/1/012078openalex-snapshot
Operating Mode Effect on Lipids Production from Rhodotorula mucilaginosa: Modelling and Simulation Trends
inferred← citeshttps://doi.org/10.1098/rsos.251014openalex-snapshot
Plantwide optimization of monoclonal antibody manufacturing platforms via mixed integer nonlinear programming
inferred← citeshttps://doi.org/10.1109/ieem62345.2024.10857245openalex-snapshot
A Preliminary Study on the Key Factors of Biopharmaceutical CDMO Ecosystem Development and Digital Resilience Building
inferred← citeshttps://doi.org/10.1186/s40794-023-00212-xopenalex-snapshot
Monoclonal antibody applications in travel medicine
inferred← citeshttps://doi.org/10.1371/journal.pntd.0007373openalex-snapshot
A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis
inferred← citeshttps://doi.org/10.1371/journal.pntd.0007860openalex-snapshot
Reassessing therapeutic antibodies for neglected and tropical diseases
inferred← citeshttps://doi.org/10.18174/471396openalex-snapshot
Production of bioengineered outer membrane vesicles as a vaccine platform
inferred← citeshttps://doi.org/10.18174/585711openalex-snapshot
Process intensification for CHO cell biomanufacturing
inferred← citeshttps://doi.org/10.2174/1573413715666190328223130openalex-snapshot
The Role of Nanofiltration in the Pathogen Safety of Biologicals: An Update
inferred← citeshttps://doi.org/10.31649/1997-9266-2020-148-1-61-76openalex-snapshot
Development of Models and Methods for Optimal Control of Project Systems Based On the Optimal Aggregation Methodology
inferred← citeshttps://doi.org/10.3389/fbioe.2022.841420openalex-snapshot
CDMOs Play a Critical Role in the Biopharmaceutical Ecosystem
inferred← citeshttps://doi.org/10.3389/fbioe.2023.1160223openalex-snapshot
Next-generation cell line selection methodology leveraging data lakes, natural language generation and advanced data analytics
inferred← citeshttps://doi.org/10.3390/ph16101384openalex-snapshot
Tumor Vaccines: Unleashing the Power of the Immune System to Fight Cancer
inferred← citeshttps://doi.org/10.3390/pr12050979openalex-snapshot
Technoeconomic Analysis of Intensified PEGylated Biopharmaceutical Recombinant Protein Production: Alpha Antitrypsin as a Model Case
inferred← citeshttps://doi.org/10.3390/pr12112563openalex-snapshot
Side-by-Side Economic Process Model for the Comparison and Evaluation of Magnetic Bead-Based Processes and Legacy Process for the Manufacturing of Monoclonal Antibodies
inferred← citeshttps://doi.org/10.3390/pr13103336openalex-snapshot
From Failures to Insights: The Role of Surge Tanks in Integrated and Continuous Bioprocessing for Antibody Production
inferred← citeshttps://doi.org/10.3390/pr7020094openalex-snapshot
Accelerating Biologics Manufacturing by Modeling or: Is Approval under the QbD and PAT Approaches Demanded by Authorities Acceptable without a Digital-Twin?
inferred← citeshttps://doi.org/10.3390/pr8091088openalex-snapshot
Digital Twins in Pharmaceutical and Biopharmaceutical Manufacturing: A Literature Review
inferred← citeshttps://doi.org/10.3390/vaccines11040841openalex-snapshot
Development of an Integrated Continuous Manufacturing Process for the rVSV-Vectored SARS-CoV-2 Candidate Vaccine
inferred← citeshttps://doi.org/10.3390/vaccines13070767openalex-snapshot
Bioengineering Outer-Membrane Vesicles for Vaccine Development: Strategies, Advances, and Perspectives
inferred← citeshttps://doi.org/10.3390/vaccines9090961openalex-snapshot
Bringing Preventive RSV Monoclonal Antibodies to Infants in Low- and Middle-Income Countries: Challenges and Opportunities
inferred← citeshttps://doi.org/10.37099/mtu.dc.etdr/1030openalex-snapshot
Virus Purification Framework And Enhancement In Aqueous Two-Phase System
inferred← citeshttps://doi.org/10.4155/ppa-2019-0011openalex-snapshot
Integrated Continuous Manufacturing in Pharmaceutical Industry: Current Evolutionary Steps Toward Revolutionary Future
inferred← citeshttps://doi.org/10.6084/m9.figshare.24997190openalex-snapshot
Additional file 1 of Monoclonal antibody applications in travel medicine
inferred← citeshttps://doi.org/10.61978/catalyx.v2i3.1336openalex-snapshot
Integrated Downstream Separation in Bioprocessing: Enhancing Yield, Purity, and Sustainability through Membrane and Adsorption Technologies
inferred← citeshttps://doi.org/10.7287/peerj.6828v0.1/reviews/1openalex-snapshot
Peer Review #1 of "Purification of plant-derived anti-virus mAb through optimized pH conditions for coupling between protein A and epoxy-activated beads (v0.1)"
inferred← citeshttps://doi.org/10.7287/peerj.6828v0.1/reviews/2openalex-snapshot
Peer Review #2 of "Purification of plant-derived anti-virus mAb through optimized pH conditions for coupling between protein A and epoxy-activated beads (v0.1)"
inferred← citeshttps://doi.org/10.7287/peerj.6828v0.1/reviews/3openalex-snapshot
Peer Review #3 of "Purification of plant-derived anti-virus mAb through optimized pH conditions for coupling between protein A and epoxy-activated beads (v0.1)"
inferred← citeshttps://doi.org/10.7287/peerj.6828v0.2/reviews/3openalex-snapshot
Peer Review #3 of "Purification of plant-derived anti-virus mAb through optimized pH conditions for coupling between protein A and epoxy-activated beads (v0.2)"
inferred← citeshttps://doi.org/10.7717/peerj.6828openalex-snapshot
Purification of plant-derived anti-virus mAb through optimized pH conditions for coupling between protein A and epoxy-activated beads
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