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Hepatocyte Polarity
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What this work says Outgoing claims: the papers this work cites, builds on, or argues with.
inferred cites → https://doi.org/10.1002/ar.20524 openalex-snapshot An in vivo Look at Vertebrate Liver Architecture: Three‐Dimensional Reconstructions from Medaka (Oryzias latipes)
inferred cites → https://doi.org/10.1002/hep.1840050427 openalex-snapshot The Liver Sieve: Considerations Concerning the Structure and Function of Endothelial Fenestrae, the Sinusoidal Wall and the Space of Disse
inferred cites → https://doi.org/10.1002/hep.1840150427 openalex-snapshot Differential Colchicine Effects on the Transport of Membrane and Secretory Proteins in Rat Hepatocytes In Vivo : Bipolar Secretion of Albumin
inferred cites → https://doi.org/10.1002/hep.1840200130 openalex-snapshot Effect of Obstructive Cholestasis on Membrane Traffic and Domain–Specific Expression of Plasma Membrane Proteins in Rat Liver Parenchmal Cells
inferred cites → https://doi.org/10.1002/hep.20155 openalex-snapshot Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors
inferred cites → https://doi.org/10.1002/hep.20600 openalex-snapshot Transdifferentiation of rat hepatocytes into biliary cells after bile duct ligation and toxic biliary injury†
inferred cites → https://doi.org/10.1002/hep.20784 openalex-snapshot CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice†
inferred cites → https://doi.org/10.1002/hep.22221 openalex-snapshot Mechanisms of hepatocyte growth factor–mediated and epidermal growth factor–mediated signaling in transdifferentiation of rat hepatocytes to biliary epithelium
inferred cites → https://doi.org/10.1002/hep.22381 openalex-snapshot Liver‐specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice†‡
inferred cites → https://doi.org/10.1002/hep.22538 openalex-snapshot Bile duct proliferation in Jag1 /fringe heterozygous mice identifies candidate modifiers of the alagille syndrome hepatic phenotype
inferred cites → https://doi.org/10.1002/hep.22610 openalex-snapshot Hepatocyte‐specific deletion of Cdc42 results in delayed liver regeneration after partial hepatectomy in mice†
inferred cites → https://doi.org/10.1002/hep.24294 openalex-snapshot Novel roles of galectin-1 in hepatocellular carcinoma cell adhesion, polarization, and in vivo tumor growth
inferred cites → https://doi.org/10.1002/hep.510270236 openalex-snapshot Efficient In Vitro vectorial transport of a fluorescent conjugated bile acid analogue by polarized hepatic hybrid WIF-B and WIF-B9 cells
inferred cites → https://doi.org/10.1002/hep.510270419 openalex-snapshot Hepatic oval cell activation in response to injury following chemically induced periportal or pericentral damage in rats
inferred cites → https://doi.org/10.1002/hep.510280122 openalex-snapshot The polarized hepatic human/rat hybrid WIF 12-1 and WIF-B cells communicate efficiently in vitro via connexin 32-constituted gap junctions
inferred cites → https://doi.org/10.1002/hep.510280336 openalex-snapshot Rho directs activation-associated changes in rat hepatic stellate cell morphology via regulation of the actin cytoskeleton
inferred cites → https://doi.org/10.1002/hep.510290149 openalex-snapshot Morphogenetic Events in Mixed Cultures of Rat Hepatocytes and Nonparenchymal Cells Maintained in Biological Matrices in the Presence of Hepatocyte Growth Factor and Epidermal Growth Factor
inferred cites → https://doi.org/10.1002/jcp.1041560303 openalex-snapshot Comparative analysis of mitogenic and morphogenic effects of HGF and EGF on rat and human hepatocytes maintained in collagen gels
inferred cites → https://doi.org/10.1002/jcp.23033 openalex-snapshot A novel human hepatoma cell line, FLC‐4, exhibits highly enhanced liver differentiation functions through the three‐dimensional cell shape
inferred cites → https://doi.org/10.1007/bf00266443 openalex-snapshot Bile duct ligation-induced redistribution of canalicular antigen in rat hepatocyte plasma membranes demonstrated by immunogold quantitation
inferred cites → https://doi.org/10.1007/bf01871942 openalex-snapshot Integral and peripheral protein composition of the apical and basolateral membrane domains in MDCK cells
inferred cites → https://doi.org/10.1007/bf02890383 openalex-snapshot Ultrastructural changes in the bile canaliculi and the lateral surfaces of rat hepatocytes during restorative proliferation
inferred cites → https://doi.org/10.1007/s00441-005-0067-2 openalex-snapshot How to induce non-polarized cells of hepatic origin to express typical hepatocyte polarity: generation of new highly polarized cell models with developed and functional bile canaliculi
inferred cites → https://doi.org/10.1038/3034 openalex-snapshot A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis
inferred cites → https://doi.org/10.1038/8977 openalex-snapshot Cdc42 controls secretory and endocytic transport to the basolateral plasma membrane of MDCK cells
inferred cites → https://doi.org/10.1038/bjc.1979.261 openalex-snapshot Sequential analysis of hepatic carcinogenesis: the comparative architecture of preneoplastic, malignant, prenatal, postnatal and regenerating liver
inferred cites → https://doi.org/10.1038/nbt1169 openalex-snapshot Conservation of gene expression signatures between zebrafish and human liver tumors and tumor progression
inferred cites → https://doi.org/10.1038/ncb1461 openalex-snapshot Phosphatidylinositol-3,4,5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cells
inferred cites → https://doi.org/10.1038/ncb2262 openalex-snapshot Myosin 1b promotes the formation of post-Golgi carriers by regulating actin assembly and membrane remodelling at the trans-Golgi network
inferred cites → https://doi.org/10.1038/ncb745 openalex-snapshot AP-4 binds basolateral signals and participates in basolateral sorting in epithelial MDCK cells
inferred cites → https://doi.org/10.1038/ng1175 openalex-snapshot Hepatocyte nuclear factor 4α controls the development of a hepatic epithelium and liver morphogenesis
inferred cites → https://doi.org/10.1038/ng905 openalex-snapshot Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes
showing the first 200 of 494
What points at this work Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred ← cites https://doi.org/10.1002/1873-3468.13477 openalex-snapshot Site‐specific phosphorylation of villin remodels the actin cytoskeleton to regulate Sendai viral glycoprotein‐mediated membrane fusion
inferred ← cites https://doi.org/10.1002/biot.201800347 openalex-snapshot 3D Primary Hepatocyte Culture Systems for Analyses of Liver Diseases, Drug Metabolism, and Toxicity: Emerging Culture Paradigms and Applications
inferred ← cites https://doi.org/10.1002/bit.27328 openalex-snapshot Optimization of 3D hydrogel microenvironment for enhanced hepatic functionality of primary human hepatocytes
inferred ← cites https://doi.org/10.1002/bit.70411 openalex-snapshot Advanced In Vitro Platforms for Experimental Liver Research: From Organoids and Liver‐on‐Chip to Omics and Artificial Intelligence
inferred ← cites https://doi.org/10.1002/hep.29798 openalex-snapshot Basolateral CD147 induces hepatocyte polarity loss by E‐cadherin ubiquitination and degradation in hepatocellular carcinoma progress
inferred ← cites https://doi.org/10.1002/jat.3753 openalex-snapshot Study of the cytotoxic and genotoxic potential of the carbonyl ruthenium(II) compound, ct‐[RuCl(CO)(dppb)(bipy)]PF6 [dppb = 1,4‐bis(diphenylphosphino)butane and bipy = 2,2′‐bipyridine], by in vitro and in vivo assays
inferred ← cites https://doi.org/10.1002/path.5202 openalex-snapshot LKB1 signaling is activated in CTNNB1 ‐mutated HCC and positively regulates β‐catenin‐dependent CTNNB1 ‐mutated HCC
inferred ← cites https://doi.org/10.1002/prp2.70311 openalex-snapshot β‐Caryophyllene Mitigates Thioacetamide‐Induced Liver Fibrosis Through CB2 ‐Mediated Suppression of Necroptosis: A Therapeutic Investigation
inferred ← cites https://doi.org/10.1002/term.2099 openalex-snapshot Three-dimensional co-culture of human hepatocytes and mesenchymal stem cells: improved functionality in long-term bioreactor cultures
inferred ← cites https://doi.org/10.1002/term.2102 openalex-snapshot Fabrication of functional 3D hepatic tissues with polarized hepatocytes by stacking endothelial cell sheetsin vitro
inferred ← cites https://doi.org/10.1007/s00204-016-1758-z openalex-snapshot Bile canaliculi formation and biliary transport in 3D sandwich-cultured hepatocytes in dependence of the extracellular matrix composition
inferred ← cites https://doi.org/10.1007/s00204-022-03329-8 openalex-snapshot Optimisation of the HepaRG cell line model for drug toxicity studies using two different cultivation conditions: advantages and limitations
inferred ← cites https://doi.org/10.1007/s00204-024-03757-8 openalex-snapshot Formation of functional, extended bile canaliculi, and increased bile acid production in sandwich-cultured human cryopreserved hepatocytes using commercially available culture medium
inferred ← cites https://doi.org/10.1007/s10565-020-09567-9 openalex-snapshot SEW2871 attenuates ANIT-induced hepatotoxicity by protecting liver barrier function via sphingosine 1-phosphate receptor-1–mediated AMPK signaling pathway
inferred ← cites https://doi.org/10.1007/s12015-017-9795-4 openalex-snapshot Phthalazinone Pyrazole Enhances the Hepatic Functions of Human Embryonic Stem Cell-Derived Hepatocyte-Like Cells via Suppression of the Epithelial-Mesenchymal Transition
inferred ← cites https://doi.org/10.1007/s12274-023-5940-3 openalex-snapshot Long-term functional maintenance of primary hepatocytes in vitro using macroporous hydrogels engineered through liquid-liquid phase separation
inferred ← cites https://doi.org/10.1016/j.aaf.2023.05.004 openalex-snapshot Impact of Metabolic disrupting chemicals on redox homeostasis, energy sensors, receptor modulation, and hormone metabolism: A comparative account in Teleost and mammalian model organisms
inferred ← cites https://doi.org/10.1016/j.aanat.2023.152157 openalex-snapshot Periphery of porcine hepatic lobes has the smallest length density of hepatic sinusoids and bile canaliculi: A stereological histological study with implications for liver biopsies
inferred ← cites https://doi.org/10.1016/j.actbio.2021.11.027 openalex-snapshot Constructing Vascularized Hepatic Tissue by Cell Assembled Viscous Tissue Sedimentation Method and Its Application for Vascular Toxicity Assessment
inferred ← cites https://doi.org/10.1016/j.ajpath.2021.02.008 openalex-snapshot Dual β-Catenin and γ-Catenin Loss in Hepatocytes Impacts Their Polarity through Altered Transforming Growth Factor-β and Hepatocyte Nuclear Factor 4α Signaling
inferred ← cites https://doi.org/10.1016/j.bej.2020.107565 openalex-snapshot Fabrication and in vitro evaluation of a packed-bed bioreactor based on galactosylated poly(ethylene terephthalate) microfibrous scaffolds
inferred ← cites https://doi.org/10.1016/j.jbiosc.2013.12.016 openalex-snapshot An in vitro liver model consisting of endothelial vascular networks surrounded by human hepatoma cell lines allows for improved hepatitis B virus replication
inferred ← cites https://doi.org/10.1038/ncb3310 openalex-snapshot Extracellular matrix scaffolding guides lumen elongation by inducing anisotropic intercellular mechanical tension
inferred ← cites https://doi.org/10.1038/s41591-019-0660-7 openalex-snapshot Three-dimensional spatially resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression
inferred ← cites https://doi.org/10.1038/srep13231 openalex-snapshot Restoration of Physiologically Responsive Low-Density Lipoprotein Receptor-Mediated Endocytosis in Genetically Deficient Induced Pluripotent Stem Cells
inferred ← cites https://doi.org/10.1038/srep37541 openalex-snapshot Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver
inferred ← cites https://doi.org/10.1039/d4bm01273a openalex-snapshot Microfluidic organ-on-a-chip models for the gut–liver axis: from structural mimicry to functional insights
inferred ← cites https://doi.org/10.1063/5.0004286 openalex-snapshot A vascular-liver chip for sensitive detection of nutraceutical metabolites from human pluripotent stem cell derivatives
inferred ← cites https://doi.org/10.1089/scd.2017.0041 openalex-snapshot Modulation of Mitochondrial DNA Copy Number to Induce Hepatocytic Differentiation of Human Amniotic Epithelial Cells
inferred ← cites https://doi.org/10.1093/gastro/goaf010 openalex-snapshot Potential function of hepatic Niemann–Pick C1-like 1: cholesterol homeostasis regulation of the canalicular lipid bilayer membrane
inferred ← cites https://doi.org/10.1093/toxsci/kfx122 openalex-snapshot From the Cover: Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening
inferred ← cites https://doi.org/10.1093/toxsci/kfx289 openalex-snapshot Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study
inferred ← cites https://doi.org/10.1101/2023.01.16.524330 openalex-snapshot HepaRG cells undergo increased levels of post-differentiation patterning in physiologic conditions when maintained as 3D cultures in paper-based scaffolds
inferred ← cites https://doi.org/10.1111/cpr.70001 openalex-snapshot Large‐Scale Production of Expandable Hepatoblast Organoids and Polarised Hepatocyte Organoids From hESCs Under 3D Static and Dynamic Suspension Conditions
inferred ← cites https://doi.org/10.1111/cts.12969 openalex-snapshot Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism, and accumulation
inferred ← cites https://doi.org/10.1111/gtc.70059 openalex-snapshot Removing Extracellular Matrix From the Cell Surface Prior to Seeding Enhances the Adhesion of Primary Human Hepatocytes to the Culture Vessel
inferred ← cites https://doi.org/10.1111/jcmm.17510 openalex-snapshot High level of polarized engraftment of porcine intrahepatic cholangiocyte organoids in decellularized liver scaffolds
inferred ← cites https://doi.org/10.1126/sciadv.abj5908 openalex-snapshot Recapitulating hepatitis E virus–host interactions and facilitating antiviral drug discovery in human liver–derived organoids
inferred ← cites https://doi.org/10.1128/jvi.00585-21 openalex-snapshot The Viral ORF3 Protein Is Required for Hepatitis E Virus Apical Release and Efficient Growth in Polarized Hepatocytes and Humanized Mice
inferred ← cites https://doi.org/10.1128/jvi.00943-19 openalex-snapshot A CRISPR Screen Identifies the Cell Polarity Determinant Crumbs 3 as an Adeno-associated Virus Restriction Factor in Hepatocytes
inferred ← cites https://doi.org/10.1128/mbio.02233-17 openalex-snapshot Interactions between the Hepatitis C Virus Nonstructural 2 Protein and Host Adaptor Proteins 1 and 4 Orchestrate Virus Release
inferred ← cites https://doi.org/10.1152/ajpcell.00051.2019 openalex-snapshot Multiple cellular pathways regulate lipid droplet homeostasis for the establishment of polarity in collagen sandwich-cultured hepatocytes
inferred ← cites https://doi.org/10.1155/2020/6354183 openalex-snapshot 3D Culture System for Liver Tissue Mimicking Hepatic Plates for Improvement of Human Hepatocyte (C3A) Function and Polarity
inferred ← cites https://doi.org/10.1371/journal.pone.0193664 openalex-snapshot A practice-changing culture method relying on shaking substantially increases mitochondrial energy metabolism and functionality of human liver cell lines
inferred ← cites https://doi.org/10.14814/phy2.12198 openalex-snapshot Hepatocytes maintain greater fluorescent bile acid accumulation and greater sensitivity to drug-induced cell death in three-dimensional matrix culture
inferred ← cites https://doi.org/10.18297/etd/2319 openalex-snapshot Development of a vascularized, induced pluripotent stem cell-derived liver-tissue mimic for therapeutic applications.
inferred ← cites https://doi.org/10.21203/rs.3.rs-2748665/v1 openalex-snapshot Dietary Effects of Sodium Propionate Supplementation on Growth, Digestive Enzyme Activity and Immune System Gene Expresion of Tropical Gar Juveniles (Atractosteus Tropicus)
showing the first 200 of 250
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