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Melatonin enhances osteoblastogenesis of senescent bone marrow stromal cells through NSD2‐mediated chromatin remodelling

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ctm2.746openalex-snapshot

Melatonin enhances osteoblastogenesis of senescent bone marrow stromal cells through NSD2‐mediated chromatin remodelling

inferredcites →https://doi.org/10.1002/jbmr.3567openalex-snapshot

Epigenetic Aging in Osteoporosis

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Regulation effects of melatonin on bone marrow mesenchymal stem cell differentiation

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Relationship between melatonin and bone resorption rhythms in premenopausal women

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Recent Progress in Engineering Mesenchymal Stem Cell Differentiation

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Roles of H3K36-specific histone methyltransferases in transcription: antagonizing silencing and safeguarding transcription fidelity

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Plasma melatonin—An index of brain aging in humans?

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Metformin induces osteoblast differentiation via orphan nuclear receptor SHP-mediated transactivation of Runx2

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Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells

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Pathophysiology of Osteoporosis

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Melatonin restores the osteoporosis-impaired osteogenic potential of bone marrow mesenchymal stem cells by preserving SIRT1-mediated intracellular antioxidant properties

inferredcites →https://doi.org/10.1016/j.molcel.2011.08.042openalex-snapshot

NSD2 Links Dimethylation of Histone H3 at Lysine 36 to Oncogenic Programming

inferredcites →https://doi.org/10.1038/cdd.2015.168openalex-snapshot

Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?

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MMSET/WHSC1 enhances DNA damage repair leading to an increase in resistance to chemotherapeutic agents

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Targeting NSD2-mediated SRC-3 liquid–liquid phase separation sensitizes bortezomib treatment in multiple myeloma

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Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases

inferredcites →https://doi.org/10.1038/s41598-017-06304-xopenalex-snapshot

Melatonin promotes osteoblast differentiation by regulating Osterix protein stability and expression

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HRP2–DPF3a–BAF complex coordinates histone modification and chromatin remodeling to regulate myogenic gene transcription

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Melatonin up‐regulates bone marrow mesenchymal stem cells osteogenic action but suppresses their mediated osteoclastogenesis via MT 2 ‐inactivated NF‐κB pathway

inferredcites →https://doi.org/10.1111/j.1600-079x.2006.00318.xopenalex-snapshot

Melatonin enhances alkaline phosphatase activity in differentiating human adult mesenchymal stem cells grown in osteogenic medium via MT2 melatonin receptors and the MEK/ERK (1/2) signaling cascade

inferredcites →https://doi.org/10.1111/j.1600-079x.2011.00875.xopenalex-snapshot

Melatonin promotes osteoblastic differentiation through the BMP/ERK/Wnt signaling pathways

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Melatonin regulates mesenchymal stem cell differentiation: a review

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Biological effects of melatonin on osteoblast/osteoclast cocultures, bone, and quality of life: Implications of a role for MT 2 melatonin receptors, MEK 1/2, and MEK 5 in melatonin‐mediated osteoblastogenesis

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Melatonin: Another avenue for treating osteoporosis?

inferredcites →https://doi.org/10.1111/jpi.12632openalex-snapshot

Melatonin‐stimulated exosomes enhance the regenerative potential of chronic kidney disease‐derived mesenchymal stem/stromal cells via cellular prion proteins

inferredcites →https://doi.org/10.1126/sciadv.aba4147openalex-snapshot

VGLL4 promotes osteoblast differentiation by antagonizing TEADs-inhibited Runx2 transcription

inferredcites →https://doi.org/10.1126/scisignal.aay8203openalex-snapshot

Myeloma cells shift osteoblastogenesis to adipogenesis by inhibiting the ubiquitin ligase MURF1 in mesenchymal stem cells

inferredcites →https://doi.org/10.1126/scitranslmed.aau9087openalex-snapshot

Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease

inferredcites →https://doi.org/10.1136/jcp.2007.048868openalex-snapshot

The cell biology of bone metabolism

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Oxidative Stress in Stem Cell Aging

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Melatonin plays critical role in mesenchymal stem cell-based regenerative medicine in vitro and in vivo

inferredcites →https://doi.org/10.1530/joe-18-0707openalex-snapshot

Suppressive effect of melatonin on osteoclast function via osteocyte calcitonin

inferredcites →https://doi.org/10.18632/oncotarget.10538openalex-snapshot

Melatonin suppresses autophagy in type 2 diabetic osteoporosis

inferredcites →https://doi.org/10.22074/cellj.2019.5507openalex-snapshot

Comparison of The Melatonin Preconditioning Efficacy between Bone Marrow and Adipose-Derived Mesenchymal Stem Cells.

inferredcites →https://doi.org/10.3389/fcell.2020.00653openalex-snapshot

The Role of SMAD2/3 in Human Embryonic Stem Cells

inferredcites →https://doi.org/10.3390/ijms140510063openalex-snapshot

Melatonin Effects on Hard Tissues: Bone and Tooth

inferredcites →https://doi.org/10.3390/ijms19051367openalex-snapshot

Co-Administration of Melatonin Effectively Enhances the Therapeutic Effects of Pioglitazone on Mesenchymal Stem Cells Undergoing Indoxyl Sulfate-Induced Senescence through Modulation of Cellular Prion Protein Expression

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Melatonin activates mitochondrial unfolded protein response to preserve osteogenic potential of senescent BMSCs via upregulating PDI-6

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Melatonin promotes osteogenic differentiation of BMSCs by regulating circZFAND1/miR-433-3p/DKK1 pathway through melatonin receptor-dependent m6A modification of circZFAND1

inferred← citeshttps://doi.org/10.1016/j.cbi.2023.110721openalex-snapshot

Codonopsis pilosula polysaccharides promote osteogenic differentiation and inhibit lipogenic differentiation of rat bone marrow stem cells by activating β-catenin

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Artesunate reverses BMSC senescence and ameliorates osteoporosis by upregulating NSD2

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