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Macrophages in human colorectal cancer are pro‐inflammatory and prime T cells towards an anti‐tumour type‐1 inflammatory response
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/ijc.24401openalex-snapshot
Interferon‐γ reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor‐associated macrophages
inferredcites →https://doi.org/10.1002/path.1027openalex-snapshot
The role of tumour‐associated macrophages in tumour progression: implications for new anticancer therapies
inferredcites →https://doi.org/10.1007/s00262-007-0425-xopenalex-snapshot
Tumors skew endothelial cells to disrupt NK cell, T-cell and macrophage functions
inferredcites →https://doi.org/10.1016/j.cyto.2010.01.009openalex-snapshot
Interferon-alpha, -beta and -gamma induce CXCL9 and CXCL10 secretion by human thyrocytes: Modulation by peroxisome proliferator-activated receptor-gamma agonists
inferredcites →https://doi.org/10.1016/j.ejca.2006.01.003openalex-snapshot
Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
inferredcites →https://doi.org/10.1016/j.immuni.2005.02.003openalex-snapshot
Primary Antitumor Immune Response Mediated by CD4+ T Cells
inferredcites →https://doi.org/10.1016/j.it.2006.04.004openalex-snapshot
Production of interferon-γ by myeloid cells – fact or fancy?
inferredcites →https://doi.org/10.1016/j.semcancer.2008.03.004openalex-snapshot
Macrophage polarization in tumour progression
inferredcites →https://doi.org/10.1016/s0076-6879(06)11009-5openalex-snapshot
[9] TM4 Microarray Software Suite
inferredcites →https://doi.org/10.1016/s1471-4906(02)02302-5openalex-snapshot
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
inferredcites →https://doi.org/10.1038/labinvest.3700389openalex-snapshot
Tumor-infiltrating T lymphocytes: friends or foes?
inferredcites →https://doi.org/10.1038/ni.1937openalex-snapshot
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
inferredcites →https://doi.org/10.1038/ni1102-991openalex-snapshot
Cancer immunoediting: from immunosurveillance to tumor escape
inferredcites →https://doi.org/10.1038/nri1964openalex-snapshot
Tuning inflammation and immunity by chemokine sequestration: decoys and more
inferredcites →https://doi.org/10.1053/j.gastro.2010.02.005openalex-snapshot
Vascular Endothelial Growth Factor and Epidermal Growth Factor Signaling Pathways as Therapeutic Targets for Colorectal Cancer
inferredcites →https://doi.org/10.1084/jem.192.9.1373openalex-snapshot
Involvement of Tweak in Interferon γ–Stimulated Monocyte Cytotoxicity
inferredcites →https://doi.org/10.1093/bioinformatics/19.2.185openalex-snapshot
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
inferredcites →https://doi.org/10.1093/bioinformatics/btf877openalex-snapshot
Identifying differentially expressed genes using false discovery rate controlling procedures
inferredcites →https://doi.org/10.1111/j.1749-6632.2009.05069.xopenalex-snapshot
Clinical Use of Interferon‐γ
inferredcites →https://doi.org/10.1126/science.1129139openalex-snapshot
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
inferredcites →https://doi.org/10.1126/science.2451290openalex-snapshot
Cell and Environment Interactions in Tumor Microregions: The Multicell Spheroid Model
inferredcites →https://doi.org/10.1158/0008-5472.can-05-4005openalex-snapshot
Distinct Role of Macrophages in Different Tumor Microenvironments
inferredcites →https://doi.org/10.1158/0008-5472.can-08-2654openalex-snapshot
Coordination of Intratumoral Immune Reaction and Human Colorectal Cancer Recurrence
inferredcites →https://doi.org/10.1158/1078-0432.ccr-06-2073openalex-snapshot
High Macrophage Infiltration along the Tumor Front Correlates with Improved Survival in Colon Cancer
inferredcites →https://doi.org/10.1186/gb-2004-5-10-r80openalex-snapshot
Bioconductor: open software development for computational biology and bioinformatics
inferredcites →https://doi.org/10.1189/jlb.0609385openalex-snapshot
Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation
inferredcites →https://doi.org/10.1189/jlb.1105656openalex-snapshot
Dual role of macrophages in tumor growth and angiogenesis
inferredcites →https://doi.org/10.1371/journal.pone.0007669openalex-snapshot
Cytokine Levels Correlate with Immune Cell Infiltration after Anti-VEGF Therapy in Preclinical Mouse Models of Breast Cancer
inferredcites →https://doi.org/10.2144/03342mt01openalex-snapshot
TM4: A Free, Open-Source System for Microarray Data Management and Analysis
inferredcites →https://doi.org/10.2202/1544-6115.1027openalex-snapshot
Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments
inferredcites →https://doi.org/10.3109/10428199209049814openalex-snapshot
Expression and Functional Role of CD54/Intercellular Adhesion Molecule-1 (ICAM-1) on Human Blood Cells
inferredcites →https://doi.org/10.3892/or.10.2.309openalex-snapshot
Prognostic significance of CD8+ T cell and macrophage peritumoral infiltration in colorectal cancer
inferredcites →https://doi.org/10.4049/jimmunol.1100889openalex-snapshot
M2 Macrophages Induced by Prostaglandin E2 and IL-6 from Cervical Carcinoma Are Switched to Activated M1 Macrophages by CD4+ Th1 Cells
inferredcites →https://doi.org/10.4049/jimmunol.180.4.2011openalex-snapshot
Plasticity of Macrophage Function during Tumor Progression: Regulation by Distinct Molecular Mechanisms
inferredcites →https://doi.org/10.4161/cc.5.7.2624openalex-snapshot
Brave Little World: Spheroids as an in vitro Model to Study Tumor-Immune-Cell Interactions
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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The density of macrophages in colorectal cancer is inversely correlated to TGF-β1 expression and patients’ survival
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The inflammation during colorectal cancer: A friend or a foe?
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MIF/CD74/CD44 pathway communicates between macrophages and colorectal Cancer cells and predicts survival of patients
inferred← citeshttps://doi.org/10.1016/j.isci.2024.109546openalex-snapshot
Disruption of CD47-SIRPα signaling restores inflammatory function in tumor-associated myeloid-derived suppressor cells
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Transcriptome landscape of myeloid cells in human skin reveals diversity, rare populations and putative DC progenitors
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Research progress on the mechanism and treatment of cachexia based on tumor microenvironment
inferred← citeshttps://doi.org/10.1016/j.oraloncology.2018.10.040openalex-snapshot
Macrophages in the microenvironment of head and neck cancer: potential targets for cancer therapy
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Uterine NK cells and macrophages in pregnancy
inferred← citeshttps://doi.org/10.1016/j.senol.2021.11.002openalex-snapshot
The influence of macrophage polarisation status and IL-6 in breast carcinoma invasion
inferred← citeshttps://doi.org/10.1016/j.smim.2013.04.001openalex-snapshot
Complement inhibition in cancer therapy
inferred← citeshttps://doi.org/10.1016/j.trecan.2016.12.004openalex-snapshot
The Heterocellular Emergence of Colorectal Cancer
inferred← citeshttps://doi.org/10.1016/j.yfrne.2020.100852openalex-snapshot
The tumour microenvironment of pituitary neuroendocrine tumours
inferred← citeshttps://doi.org/10.1038/bjc.2017.356openalex-snapshot
TAMeless traitors: macrophages in cancer progression and metastasis
inferred← citeshttps://doi.org/10.1038/cti.2016.21openalex-snapshot
Gut macrophage phenotype is dependent on the tumor microenvironment in colorectal cancer
inferred← citeshttps://doi.org/10.1038/s41467-018-06268-0openalex-snapshot
Macrophage-secreted interleukin-35 regulates cancer cell plasticity to facilitate metastatic colonization
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Cyclodextrin-based host-guest complexes loaded with regorafenib for colorectal cancer treatment
inferred← citeshttps://doi.org/10.1038/s41467-024-45471-0openalex-snapshot
Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche
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BioTarget: A Computational Framework Identifying Cancer Type Specific Transcriptional Targets of Immune Response Pathways
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Secreted Factors from Colorectal and Prostate Cancer Cells Skew the Immune Response in Opposite Directions
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Use of carbosilane dendrimer to switch macrophage polarization for the acquisition of antitumor functions
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Atractylenolide II inhibits tumor-associated macrophages (TAMs)-induced lung cancer cell metastasis
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Ionizing radiation reduces the capacity of activated macrophages to induce T-cell proliferation, but does not trigger dendritic cell-mediated non-targeted effects
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Tumor cell-derived microparticles polarize M2 tumor-associated macrophages for tumor progression
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Immunological differences between colorectal cancer and normal mucosa uncover a prognostically relevant immune cell profile
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GBP-1 acts as a tumor suppressor in colorectal cancer cells
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The inflammatory microenvironment in vestibular schwannoma
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Colonic macrophage polarization in homeostasis, inflammation, and cancer
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Cervical Cancer Cell Supernatants Induce a Phenotypic Switch from U937-Derived Macrophage-Activated M1 State into M2-Like Suppressor Phenotype with Change in Toll-Like Receptor Profile
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Papel do receptor ST2 no desenvolvimento de carcinoma espinocelular induzido quimicamente
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Quantificação dos macrófagos M1 e M2 associados a mastocitomas cutâneos caninos
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Liquid-based three-dimensional tumor models for cancer research and drug discovery
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CXCL16 suppresses liver metastasis of colorectal cancer by promoting TNF-α-induced apoptosis by tumor-associated macrophages
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Complement and macrophage crosstalk during process of angiogenesis in tumor progression
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Extracellular vesicles containing MFGE8 from colorectal cancer facilitate macrophage efferocytosis
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Colorectal cancer-derived microvesicles modulate differentiation of human monocytes to macrophages
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STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment
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Chemokines modulate the tumour microenvironment in pituitary neuroendocrine tumours
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Grp94 in complexes with IgG is a soluble diagnostic marker of gastrointestinal tumors and displays immune-stimulating activity on peripheral blood immune cells
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Contact-dependent carcinoma aggregate dispersion by M2a macrophages via ICAM-1 and β2 integrin interactions
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Conditioned Medium from Cultured Colorectal Cancer Cells Affects Peripheral Blood Mononuclear Cells Inflammatory Phenotype in Vitro.
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CD40 signaling instructs chronic lymphocytic leukemia cells to attract monocytes via the CCR2 axis
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Prognostic Role of CD68+ and CD163+ Tumour-Associated Macrophages and PD-L1 Expression in Oral Squamous Cell Carcinoma: A Meta-Analysis
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Macrophage Cytokines: Involvement in Immunity and Infectious Diseases
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Chamaejasmenin B, an Inhibitor for Metastatic Outgrowth, Reversed M2-Dominant Macrophage Polarization in Breast Tumor Microenvironment
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The Give-and-Take Interaction Between the Tumor Microenvironment and Immune Cells Regulating Tumor Progression and Repression
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Macrophage-derived exosome promotes regulatory T cell differentiation in malignant pleural effusion
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NF-κB signaling pathway in tumor microenvironment
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Targeting Macrophages in Cancer: From Bench to Bedside
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Unveiling the contribution of tumor-associated macrophages in driving epithelial-mesenchymal transition: a review of mechanisms and therapeutic Strategies
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Role of tumor associated macrophages in tumor angiogenesis and lymphangiogenesis
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Granulocyte Colony Stimulating Factor Expression in Breast Cancer and Its Association with Carbonic Anhydrase IX and Immune Checkpoints
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Data Driven Mathematical Model of FOLFIRI Treatment for Colon Cancer
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Tumor Microenvironment and Hydrogel-Based 3D Cancer Models for In Vitro Testing Immunotherapies
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Implications of Rectal Cancer Radiotherapy on the Immune Microenvironment: Allies and Foes to Therapy Resistance and Patients’ Outcome
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Cytokines and Chemokines in Cancer Cachexia and Its Long-Term Impact on COVID-19
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Decidua Basalis Mesenchymal Stem Cells Favor Inflammatory M1 Macrophage Differentiation In Vitro
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Pro-Tumoral Inflammatory Myeloid Cells as Emerging Therapeutic Targets
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The Role of Tumor Microenvironment Cells in Colorectal Cancer (CRC) Cachexia
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Recruitment of M1 Macrophages May Not Be Critical for Protection against Colitis-Associated Tumorigenesis
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Systemic Interleukins’ Profile in Early and Advanced Colorectal Cancer
inferred← citeshttps://doi.org/10.3390/ijms26115336openalex-snapshot
Regulation and Function of Tumor-Associated Macrophages (TAMs) in Colorectal Cancer (CRC): The Role of the SRIF System in Macrophage Regulation
inferred← citeshttps://doi.org/10.3390/ijms26188867openalex-snapshot
An Integrative Bioinformatics Approach to Investigating TIMP3 and Immune Cell Infiltration: Prognostic and Clinicopathological Implications
inferred← citeshttps://doi.org/10.3390/immuno2030028openalex-snapshot
Cervical Cancer Outcome and Tumor-Associated Macrophages: Research Evidence
inferred← citeshttps://doi.org/10.3390/jcm10235559openalex-snapshot
Monocyte Chemotactic Proteins (MCP) in Colorectal Adenomas Are Differently Expressed at the Transcriptional and Protein Levels: Implications for Colorectal Cancer Prevention
inferred← citeshttps://doi.org/10.3390/jcm9123947openalex-snapshot
Data Driven Mathematical Model of Colon Cancer Progression
inferred← citeshttps://doi.org/10.3748/wjg.v30.i20.2689openalex-snapshot
Kinesin 26B modulates M2 polarization of macrophage by activating cancer-associated fibroblasts to aggravate gastric cancer occurrence and metastasis
inferred← citeshttps://doi.org/10.3892/etm.2019.8068openalex-snapshot
M2 tumor‑associated macrophages promote tumor progression in non‑small‑cell lung cancer
inferred← citeshttps://doi.org/10.3892/mmr.2014.3018openalex-snapshot
Dynamic changes and functions of macrophages and M1/M2 subpopulations during ulcerative colitis-associated carcinogenesis in an AOM/DSS mouse model
inferred← citeshttps://doi.org/10.3969/j.issn.1672-7347.2012.06.017openalex-snapshot
[Effect of macrophages on ulcerative colitis-associated carcinogenesis].
inferred← citeshttps://doi.org/10.4251/wjgo.v7.i10.221openalex-snapshot
Immune cell interplay in colorectal cancer prognosis
inferred← citeshttps://doi.org/10.53846/goediss-6238openalex-snapshot
Einfluss des Prolyl-4-Hydroxylase-Domäne 2-Enzyms auf die Migration der myeloischen Zelllinien RAW und J774
inferred← citeshttps://doi.org/10.5411/wji.v6.i1.9openalex-snapshot
Role of tumor associated macrophages in regulating pancreatic cancer progression
inferred← citeshttps://doi.org/10.5582/bst.2017.01259openalex-snapshot
Yin-yang regulating effects of cancer-associated genes, proteins, and cells: An ancient Chinese concept in vogue in modern cancer research
inferred← citeshttps://doi.org/10.5772/intechopen.1007011openalex-snapshot
Perspective Chapter: Monocytes on the Interface of Metabolic Disorders and Colorectal Cancer
inferred← citeshttps://doi.org/10.70675/4e035d32zbda7z4539z8911z00e1344b619fopenalex-snapshot
Etude de CD160, récepteur activateur des cellules NK dans le mélanome : une potentielle cible thérapeutique à l'ère de l'immunothérapie ?
inferred← citeshttps://doi.org/10.70675/606044acz15f8z45d8z9566ze0de40cff550openalex-snapshot
Les macrophages au sein du microenvironnement tumoral : étude et modulation des mécanismes moléculaires et cellulaires de la réponse anti-tumorale au cours de carcinoses péritonéales
inferred← citeshttps://doi.org/10.70675/bdde7470z307dz42bfzb795zf574ce0f1d2bopenalex-snapshot
Macrophages associés à la tumeur dans les carcinomes épidermoïdes des voies aérodigestives supérieures
inferred← citeshttps://doi.org/10.70675/dee45c70z4d48z4905zba48z79e660bad55aopenalex-snapshot
Conséquences de l'interaction des plaquettes avec les cellules cancéreuses sur le développement de la tumeur et la formation de métastases : cas du cancer colorectal
inferred← citeshttps://doi.org/10.7150/ijbs.29836openalex-snapshot
Elevated CD163+/CD68+ Ratio at Tumor Invasive Front is Closely Associated with Aggressive Phenotype and Poor Prognosis in Colorectal Cancer
inferred← citeshttps://doi.org/10.7150/thno.29098openalex-snapshot
Chemoresistance of Cancer Cells: Requirements of Tumor Microenvironment-mimicking In Vitro Models in Anti-Cancer Drug Development
inferred← citeshttps://doi.org/10.7150/thno.43938openalex-snapshot
An ultralow dose of the NADPH oxidase inhibitor diphenyleneiodonium (DPI) is an economical and effective therapeutic agent for the treatment of colitis-associated colorectal cancer
inferred← citeshttps://doi.org/10.7314/apjcp.2013.14.2.1003openalex-snapshot
Correlations of Tumor-associated Macrophage Subtypes with Liver Metastases of Colorectal Cancer
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