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Inhibition of p38 MAPK sensitizes tumour cells to cisplatin‐induced apoptosis mediated by reactive oxygen species and JNK
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1 of the 61 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-28): 10.1038/nature10167 (notice 2018-07-25).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/cncr.11940openalex-snapshot
Prognostic significance of phosphorylated P38 mitogen‐activated protein kinase and HER‐2 expression in lymph node‐positive breast carcinoma
inferredcites →https://doi.org/10.1002/path.1910openalex-snapshot
The p38 transduction pathway in prostatic neoplasia
inferredcites →https://doi.org/10.1002/path.1975openalex-snapshot
High‐level expression, activation, and subcellular localization of p38‐MAP kinase in thyroid neoplasms
inferredcites →https://doi.org/10.1007/s10495-005-3372-zopenalex-snapshot
p38 MAP kinase plays a role in G2 checkpoint activation and inhibits apoptosis of human B cell lymphoma cells treated with etoposide
inferredcites →https://doi.org/10.1007/s10495-011-0680-3openalex-snapshot
Cryptotanshinone induces ER stress-mediated apoptosis in HepG2 and MCF7 cells
inferredcites →https://doi.org/10.1007/s10555-008-9112-4openalex-snapshot
Signal cross talks for sustained MAPK activation and cell migration: the potential role of reactive oxygen species
inferredcites →https://doi.org/10.1007/s10555-008-9123-1openalex-snapshot
Dual-specificity MAP kinase phosphatases (MKPs) and cancer
inferredcites →https://doi.org/10.1016/b978-0-12-396456-4.00009-2openalex-snapshot
Protein Tyrosine Phosphatases in Cancer
inferredcites →https://doi.org/10.1016/j.bcp.2009.12.006openalex-snapshot
Emodin enhances sensitivity of gallbladder cancer cells to platinum drugs via glutathion depletion and MRP1 downregulation
inferredcites →https://doi.org/10.1016/j.bcp.2011.06.007openalex-snapshot
Catalase overexpression in mammary cancer cells leads to a less aggressive phenotype and an altered response to chemotherapy
inferredcites →https://doi.org/10.1016/j.canlet.2006.10.007openalex-snapshot
Activation of mitogen-activated protein kinases by cisplatin and their role in cisplatin-resistance
inferredcites →https://doi.org/10.1016/j.ccr.2006.11.024openalex-snapshot
p53-Deficient Cells Rely on ATM- and ATR-Mediated Checkpoint Signaling through the p38MAPK/MK2 Pathway for Survival after DNA Damage
inferredcites →https://doi.org/10.1016/j.ccr.2006.12.013openalex-snapshot
p38α MAP Kinase as a Sensor of Reactive Oxygen Species in Tumorigenesis
inferredcites →https://doi.org/10.1016/j.cell.2004.12.041openalex-snapshot
Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases
inferredcites →https://doi.org/10.1016/j.cell.2011.07.020openalex-snapshot
Global Proteomic Assessment of the Classical Protein-Tyrosine Phosphatome and “Redoxome”
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2005.10.056openalex-snapshot
JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species
inferredcites →https://doi.org/10.1016/s0092-8674(00)00116-1openalex-snapshot
Signal Transduction by the JNK Group of MAP Kinases
inferredcites →https://doi.org/10.1021/bi900655fopenalex-snapshot
Structural Bioinformatics-Based Prediction of Exceptional Selectivity of p38 MAP Kinase Inhibitor PH-797804
inferredcites →https://doi.org/10.1021/jm9012906openalex-snapshot
Selective p38α Inhibitors Clinically Evaluated for the Treatment of Chronic Inflammatory Disorders
inferredcites →https://doi.org/10.1038/43459openalex-snapshot
Cell transformation by the superoxide-generating oxidase Mox1
inferredcites →https://doi.org/10.1038/emboj.2012.122openalex-snapshot
The p57 CDKi integrates stress signals into cell‐cycle progression to promote cell survival upon stress
inferredcites →https://doi.org/10.1038/nature10167openalex-snapshot
Selective killing of cancer cells by a small molecule targeting the stress response to ROS
inferredcites →https://doi.org/10.1038/ng2033openalex-snapshot
p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway
inferredcites →https://doi.org/10.1038/ng2037openalex-snapshot
p38α MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation
inferredcites →https://doi.org/10.1038/nm.2512openalex-snapshot
miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response
inferredcites →https://doi.org/10.1038/nrc2694openalex-snapshot
Signal integration by JNK and p38 MAPK pathways in cancer development
inferredcites →https://doi.org/10.1038/nrd2803openalex-snapshot
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
inferredcites →https://doi.org/10.1038/sj.leu.2404200openalex-snapshot
Inhibition of p38α MAPK enhances proteasome inhibitor-induced apoptosis of myeloma cells by modulating Hsp27, Bcl-XL, Mcl-1 and p53 levels in vitro and inhibits tumor growth in vivo
inferredcites →https://doi.org/10.1038/sj.onc.1203887openalex-snapshot
CL100/MKP-1 modulates JNK activation and apoptosis in response to cisplatin
inferredcites →https://doi.org/10.1038/sj.onc.1206979openalex-snapshot
DNA-damaging reagents induce apoptosis through reactive oxygen species-dependent Fas aggregation
inferredcites →https://doi.org/10.1042/bj20100323openalex-snapshot
Mechanisms and functions of p38 MAPK signalling
inferredcites →https://doi.org/10.1073/pnas.0702955104openalex-snapshot
Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer
inferredcites →https://doi.org/10.1073/pnas.1015013108openalex-snapshot
Genetic analysis of specific and redundant roles for p38α and p38β MAPKs during mouse development
inferredcites →https://doi.org/10.1073/pnas.1105941108openalex-snapshot
Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress
inferredcites →https://doi.org/10.1073/pnas.1137463100openalex-snapshot
Involvement of multiple signaling pathways in follicular lymphoma transformation: p38-mitogen-activated protein kinase as a target for therapy
inferredcites →https://doi.org/10.1073/pnas.81.7.2085openalex-snapshot
Active oxygen acts as a promoter of transformation in mouse embryo C3H/10T1/2/C18 fibroblasts.
inferredcites →https://doi.org/10.1074/jbc.m111.323709openalex-snapshot
p38α Mediates Cell Survival in Response to Oxidative Stress via Induction of Antioxidant Genes
inferredcites →https://doi.org/10.1074/jbc.m705142200openalex-snapshot
Several Dual Specificity Phosphatases Coordinate to Control the Magnitude and Duration of JNK Activation in Signaling Response to Oxidative Stress
inferredcites →https://doi.org/10.1093/jb/mvr104openalex-snapshot
Regulation of protein tyrosine phosphatases by reversible oxidation
inferredcites →https://doi.org/10.1111/eci.12003openalex-snapshot
Phosphorylated p38 and JNK MAPK proteins in hepatocellular carcinoma
inferredcites →https://doi.org/10.1124/jpet.109.158329openalex-snapshot
Anti-Inflammatory Properties of a Novel N-Phenyl Pyridinone Inhibitor of p38 Mitogen-Activated Protein Kinase: Preclinical-to-Clinical Translation
inferredcites →https://doi.org/10.1128/mcb.00949-09openalex-snapshot
p38 Mitogen-Activated Protein Kinase Promotes Cell Survival in Response to DNA Damage but Is Not Required for the G2 DNA Damage Checkpoint in Human Cancer Cells
inferredcites →https://doi.org/10.1128/mcb.12.3.954openalex-snapshot
Induction of Mammary Tumors by Expression of Polyomavirus Middle T Oncogene: A Transgenic Mouse Model for Metastatic Disease
inferredcites →https://doi.org/10.1146/annurev.pharmtox.48.113006.094606openalex-snapshot
Apoptosis Signal-Regulating Kinase 1 in Stress and Immune Response
inferredcites →https://doi.org/10.1158/0008-5472.can-06-3283openalex-snapshot
Sensitizing Effect of Galectin-7 in Urothelial Cancer to Cisplatin through the Accumulation of Intracellular Reactive Oxygen Species
inferredcites →https://doi.org/10.1158/0008-5472.can-08-4455openalex-snapshot
p38δ Mitogen-Activated Protein Kinase Is Essential for Skin Tumor Development in Mice
inferredcites →https://doi.org/10.1158/0008-5472.can-09-1636openalex-snapshot
Inhibition of the p38 Kinase Suppresses the Proliferation of Human ER-Negative Breast Cancer Cells
inferredcites →https://doi.org/10.1158/0008-5472.can-11-4201openalex-snapshot
Impact of Intertumoral Heterogeneity on Predicting Chemotherapy Response of BRCA1-Deficient Mammary Tumors
inferredcites →https://doi.org/10.1158/1078-0432.ccr-09-2434openalex-snapshot
A High-Throughput Pharmaceutical Screen Identifies Compounds with Specific Toxicity against BRCA2-Deficient Tumors
inferredcites →https://doi.org/10.1158/1535-7163.mct-06-0711openalex-snapshot
MAP-ing glioma invasion: Mitogen-activated protein kinase kinase 3 and p38 drive glioma invasion and progression and predict patient survival
inferredcites →https://doi.org/10.1177/1947601911425832openalex-snapshot
Anti-miR-203 Upregulates SOCS3 Expression in Breast Cancer Cells and Enhances Cisplatin Chemosensitivity
inferredcites →https://doi.org/10.1210/en.2007-0988openalex-snapshot
Reactive Oxygen Species-Mediated Pancreatic β-Cell Death Is Regulated by Interactions between Stress-Activated Protein Kinases, p38 and c-Jun N-Terminal Kinase, and Mitogen-Activated Protein Kinase Phosphatases
inferredcites →https://doi.org/10.1242/jcs.03266openalex-snapshot
Diverse physiological functions for dual-specificity MAP kinase phosphatases
inferredcites →https://doi.org/10.1371/journal.pone.0028406openalex-snapshot
Balance between MKK6 and MKK3 Mediates p38 MAPK Associated Resistance to Cisplatin in NSCLC
inferredcites →https://doi.org/10.2741/1798openalex-snapshot
Oxidative stress and apoptosis: a new treatment paradigm in cancer
inferredcites →https://doi.org/10.3892/or.15.5.1175openalex-snapshot
Cellular components involved in the cell death induced by cisplatin in the absence of p53 activation
inferredcites →https://doi.org/10.4161/auto.5.7.9252openalex-snapshot
Inhibition of p38α unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism
inferredcites →https://doi.org/10.4161/cbt.7.12.7067openalex-snapshot
Cancer cell killing via ROS: To increase or decrease, that is the question
inferredcites →https://doi.org/10.4161/cbt.8.20.9648openalex-snapshot
Mitochondrial ROS and radiation induced transformation in mouse embryonic fibroblasts
inferredcites →https://doi.org/10.4161/cc.6.11.4315openalex-snapshot
Genetic Deficiency of p38α Reveals its Critical Role in Myoblast Cell Cycle Exit:The p38α-JNK Connection
inferredcites →https://doi.org/10.7150/ijbs.5.44openalex-snapshot
Non-Classical P38 Map Kinase Functions: Cell Cycle Checkpoints and Survival
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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inferred← citeshttps://doi.org/10.1002/1878-0261.12411openalex-snapshot
EGFR and Prion protein promote signaling via FOXO 3a‐ KLF 5 resulting in clinical resistance to platinum agents in colorectal cancer
inferred← citeshttps://doi.org/10.1002/1878-0261.12810openalex-snapshot
In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor
inferred← citeshttps://doi.org/10.1002/1878-0261.70204openalex-snapshot
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
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DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss
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PI16 attenuates response to sorafenib and represents a predictive biomarker in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1002/ctd2.70126openalex-snapshot
CEACAM6 silencing suppresses tumour growth and sensitises cholangiocarcinoma to cisplatin
inferred← citeshttps://doi.org/10.1007/978-3-662-44559-4_25openalex-snapshot
Mechanisms of Uptake and Interaction of Platinum Based Drugs in Eukaryotic Cells
inferred← citeshttps://doi.org/10.1007/978-981-19-6442-8_16openalex-snapshot
Targeted Therapies in Gallbladder Cancer: Current Status and Future Perspectives
inferred← citeshttps://doi.org/10.1007/s00018-017-2575-0openalex-snapshot
Molecularly targeted therapies for p53-mutant cancers
inferred← citeshttps://doi.org/10.1007/s00204-017-2066-yopenalex-snapshot
t-BuOOH induces ferroptosis in human and murine cell lines
inferred← citeshttps://doi.org/10.1007/s00204-019-02413-wopenalex-snapshot
Cell–cell contacts protect against t-BuOOH-induced cellular damage and ferroptosis in vitro
inferred← citeshttps://doi.org/10.1007/s10495-015-1182-5openalex-snapshot
Low zinc environment induces stress signaling, senescence and mixed cell death modalities in colon cancer cells
inferred← citeshttps://doi.org/10.1007/s11030-025-11291-7openalex-snapshot
Advances in targeting p38 MAPK for cancer therapy: insights from molecular pharmacology and medicinal chemistry
inferred← citeshttps://doi.org/10.1016/j.algal.2025.103949openalex-snapshot
Anticancer effects of the Melosira nummuloides extract on hepatocellular carcinoma cells through JAK2/STAT3 and MAPK pathway inhibition
inferred← citeshttps://doi.org/10.1016/j.archoralbio.2020.104981openalex-snapshot
RETRACTED: p38 Mitogen-activated protein kinase modulates cisplatin resistance in Head and Neck Squamous Cell Carcinoma cells
inferred← citeshttps://doi.org/10.1016/j.bbcan.2025.189297openalex-snapshot
Unraveling the role of deubiquitinating enzymes on cisplatin resistance in several cancers
inferred← citeshttps://doi.org/10.1016/j.bbcan.2025.189387openalex-snapshot
Raf-kinase inhibitor protein (RKIP): A therapeutic target in colon cancer
inferred← citeshttps://doi.org/10.1016/j.bbrc.2016.07.035openalex-snapshot
DUSP1 induces paclitaxel resistance through the regulation of p-glycoprotein expression in human ovarian cancer cells
inferred← citeshttps://doi.org/10.1016/j.bbrc.2019.02.015openalex-snapshot
Lenvatinib induces death of human hepatocellular carcinoma cells harboring an activated FGF signaling pathway through inhibition of FGFR–MAPK cascades
inferred← citeshttps://doi.org/10.1016/j.bcp.2022.115124openalex-snapshot
Antitumor and antimigration effects of a new Pt compound on neuroblastoma cells
inferred← citeshttps://doi.org/10.1016/j.bcp.2025.116820openalex-snapshot
STM2457 decreases m6A methylation to reduce cisplatin-induced ototoxicity via MAPK signaling
inferred← citeshttps://doi.org/10.1016/j.biocel.2015.07.014openalex-snapshot
The presence of Estrogen Receptor β modulates the response of breast cancer cells to therapeutic agents
inferred← citeshttps://doi.org/10.1016/j.biocel.2020.105732openalex-snapshot
ROS enhances the cytotoxicity of cisplatin by inducing apoptosis and autophagy in tongue squamous cell carcinoma cells
inferred← citeshttps://doi.org/10.1016/j.biopha.2022.113345openalex-snapshot
Cellular landscaping of cisplatin resistance in cervical cancer
inferred← citeshttps://doi.org/10.1016/j.canlet.2018.03.016openalex-snapshot
15-Deoxy-Δ12,14-prostaglandin J2 activates PI3K-Akt signaling in human breast cancer cells through covalent modification of the tumor suppressor PTEN at cysteine 136
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Gossypetin is a novel MKK3 and MKK6 inhibitor that suppresses esophageal cancer growth in vitro and in vivo
inferred← citeshttps://doi.org/10.1016/j.cbi.2019.108849openalex-snapshot
Multiple cytotoxic effects of gamabufotalin against human glioblastoma cell line U-87
inferred← citeshttps://doi.org/10.1016/j.cbi.2021.109662openalex-snapshot
Nephrotoxicity induced by cisplatin is primarily due to the activation of the 5-hydroxytryptamine degradation system in proximal renal tubules
inferred← citeshttps://doi.org/10.1016/j.ccell.2018.04.010openalex-snapshot
Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells
inferred← citeshttps://doi.org/10.1016/j.celrep.2018.08.020openalex-snapshot
Cell-to-Cell Heterogeneity in p38-Mediated Cross-Inhibition of JNK Causes Stochastic Cell Death
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.111375openalex-snapshot
Regulation of Claspin by the p38 stress-activated protein kinase protects cells from DNA damage
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2024.114392openalex-snapshot
Low toxicity ginsenoside Rg1-carbon nanodots as a potential therapeutic agent for human non-small cell lung cancer
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Systems-level exploration of Withania somnifera-derived phytochemicals against breast cancer: A network pharmacology and molecular modeling approach
inferred← citeshttps://doi.org/10.1016/j.fbio.2025.106073openalex-snapshot
Liriope muscari baily saponin C induces apoptosis and autophagy in HCT116 cells via ROS generation
inferred← citeshttps://doi.org/10.1016/j.imbio.2015.09.012openalex-snapshot
Impact of p38 mitogen-activated protein kinase inhibition on immunostimulatory properties of human 6-sulfo LacNAc dendritic cells
inferred← citeshttps://doi.org/10.1016/j.isci.2022.104827openalex-snapshot
EZH2 T367 phosphorylation activates p38 signaling through lysine methylation to promote breast cancer progression
inferred← citeshttps://doi.org/10.1016/j.jpba.2021.114039openalex-snapshot
Ultra-high performance supercritical fluid chromatography method for separation and quantitation of saikosaponins in herbal medicine
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3-Bromopyruvate treatment induces alterations of metabolic and stress-related pathways in glioblastoma cells
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Beauvericin, produced by Fusarium oxysporum inhibits bisphenol A-induced proliferation of human breast cancer cell line by regulating ERα/p38 pathway
inferred← citeshttps://doi.org/10.1016/j.marenvres.2023.106294openalex-snapshot
Modulatory role ulexit against thiamethoxam-induced hematotoxicity/hepatotoxicity oxidative stress and immunotoxicity in Oncorhynchus mykiss
inferred← citeshttps://doi.org/10.1016/j.mrgentox.2018.05.018openalex-snapshot
The role of p38 MAPK pathway in p53 compromised state and telomere mediated DNA damage response
inferred← citeshttps://doi.org/10.1016/j.mrrev.2024.108513openalex-snapshot
Mechanistic insights into cisplatin response in breast tumors: Molecular determinants and drug/nanotechnology-based therapeutic opportunities
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Characterization of the modulatory effect of zeaxanthin isolated from maize kernels on cellular signaling pathways associated with hyperglycemia-induced HepG2 cell proliferation
inferred← citeshttps://doi.org/10.1016/j.pharmr.2025.100088openalex-snapshot
miR-155 aberrant expression impairs tumor rejection because of its targeting of ICOSL and multiple pathways implicated in the antitumor response
inferred← citeshttps://doi.org/10.1016/j.redox.2018.02.017openalex-snapshot
Age-dependent regulation of antioxidant genes by p38α MAPK in the liver
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Re-establishing the comprehension of phytomedicine and nanomedicine in inflammation-mediated cancer signaling
inferred← citeshttps://doi.org/10.1016/j.stemcr.2017.11.021openalex-snapshot
Regulation of Mammary Luminal Cell Fate and Tumorigenesis by p38α
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The P38α rs3804451 Variant Predicts Chemotherapy Response and Survival of Patients with Non–Small Cell Lung Cancer Treated with Platinum-Based Chemotherapy
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Discovery of Type II Inhibitors of TGFβ-Activated Kinase 1 (TAK1) and Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2)
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Proline isomerisation as a novel regulatory mechanism for p38MAPK activation and functions
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miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells
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The nucleotide excision repair protein XPC is essential for bulky DNA adducts to promote interleukin-6 expression via the activation of p38-SAPK
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Role of p38 MAP kinase in cancer stem cells and metastasis
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p38 MAPK pathway and its interaction with TRF2 in cisplatin induced chemotherapeutic response in head and neck cancer
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Signaling pathways and therapeutic interventions in gastric cancer
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Anastasis confers ovarian cancer cells increased malignancy through elevated p38 MAPK activation
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Caspase 3/GSDME-dependent pyroptosis contributes to chemotherapy drug-induced nephrotoxicity
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p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasis
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Regulation of tumor angiogenesis and mesenchymal–endothelial transition by p38α through TGF-β and JNK signaling
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Multi-omics characterization of autophagy-related molecular features for therapeutic targeting of autophagy
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Diversity and versatility of p38 kinase signalling in health and disease
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p38 MAPK activation through B7-H3-mediated DUSP10 repression promotes chemoresistance
inferred← citeshttps://doi.org/10.1042/bcj20220102openalex-snapshot
Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway
inferred← citeshttps://doi.org/10.1073/pnas.1414358111openalex-snapshot
Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade
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Binding mechanism of inhibitors to DFG-in and DFG-out P38α deciphered using multiple independent Gaussian accelerated molecular dynamics simulations and deep learning
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Romidepsin alone or in combination with anti-CD20 chimeric antigen receptor expanded natural killer cells targeting Burkitt lymphoma in vitro and in immunodeficient mice
inferred← citeshttps://doi.org/10.1093/carcin/bgz167openalex-snapshot
EVI1 induces autophagy to promote drug resistance via regulation of ATG7 expression in leukemia cells
inferred← citeshttps://doi.org/10.1097/cad.0000000000000414openalex-snapshot
Id4 promotes cisplatin resistance in lung cancer through the p38 MAPK pathway
inferred← citeshttps://doi.org/10.1101/2020.03.10.985994openalex-snapshot
Model-based identification of the crosstalks and feedbacks that determine the doxorubicin response dynamics of the JNK-p38-p53 network
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Roles of p38α mitogen‐activated protein kinase in mouse models of inflammatory diseases and cancer
inferred← citeshttps://doi.org/10.1111/jcmm.17602openalex-snapshot
7‐Epitaxol induces apoptosis in cisplatin‐resistant head and neck squamous cell carcinoma via suppression of AKT and MAPK signalling
inferred← citeshttps://doi.org/10.1111/jcmm.18329openalex-snapshot
Molecular and functional characterization of reversible‐sunitinib‐tolerance state in human renal cell carcinoma
inferred← citeshttps://doi.org/10.1111/jop.12707openalex-snapshot
Role of p38 MAPK in disease relapse and therapeutic resistance by maintenance of cancer stem cells in head and neck squamous cell carcinoma
inferred← citeshttps://doi.org/10.1158/0008-5472.can-14-0673openalex-snapshot
Phosphatase PTP4A3 Promotes Triple-Negative Breast Cancer Growth and Predicts Poor Patient Survival
inferred← citeshttps://doi.org/10.1158/0008-5472.can-15-0173openalex-snapshot
The Stress Kinase p38α as a Target for Cancer Therapy
inferred← citeshttps://doi.org/10.1186/s12967-018-1471-1openalex-snapshot
Cisplatin based therapy: the role of the mitogen activated protein kinase signaling pathway
inferred← citeshttps://doi.org/10.1186/s13046-019-1173-4openalex-snapshot
Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells
inferred← citeshttps://doi.org/10.1186/s43088-023-00401-9openalex-snapshot
Integrated in vivo and in silico evaluation of sweet basil oil as a protective agent against cisplatin-induced neurotoxicity in mice
inferred← citeshttps://doi.org/10.1371/journal.pone.0147011openalex-snapshot
Cadmium Activates Multiple Signaling Pathways That Coordinately Stimulate Akt Activity to Enhance c-Myc mRNA Stability
inferred← citeshttps://doi.org/10.1371/journal.pone.0342707openalex-snapshot
Mechanism of action of cisplatin on Na+/K+ ATPase of Caco-2 colon cells in vitro
inferred← citeshttps://doi.org/10.15476/elte.2021.098openalex-snapshot
Anti-migratory function of PMCA4b is mediated by p38 MAPK and actin cytoskeleton remodeling in BRAF mutant melanoma cells
inferred← citeshttps://doi.org/10.18632/aging.100796openalex-snapshot
Targeting of non-oncogene addiction
inferred← citeshttps://doi.org/10.18632/oncoscience.167openalex-snapshot
Inhibition of 19S proteasome-associated deubiquitinases by metal-containing compounds
inferred← citeshttps://doi.org/10.18632/oncotarget.17879openalex-snapshot
trans-4,4’-Dihydroxystilbene (DHS) inhibits human neuroblastoma tumor growth and induces mitochondrial and lysosomal damages in neuroblastoma cell lines
inferred← citeshttps://doi.org/10.18632/oncotarget.3816openalex-snapshot
Pharmacological inhibition of p38 MAPK reduces tumor growth in patient-derived xenografts from colon tumors
inferred← citeshttps://doi.org/10.18632/oncotarget.3902openalex-snapshot
Exploiting the potential of autophagy in cisplatin therapy: A new strategy to overcome resistance
inferred← citeshttps://doi.org/10.18632/oncotarget.6574openalex-snapshot
MKP1 mediates chemosensitizer effects of E1a in response to cisplatin in non-small cell lung carcinoma cells
inferred← citeshttps://doi.org/10.2147/cmar.s169476openalex-snapshot
Deguelin induces apoptosis in colorectal cancer cells by activating the p38 MAPK pathway
inferred← citeshttps://doi.org/10.2147/jep.s267383openalex-snapshot
Advances in Our Understanding of the Molecular Mechanisms of Action of Cisplatin in Cancer Therapy
inferred← citeshttps://doi.org/10.2147/ott.s243953openalex-snapshot
Polyphyllin VI Induces Apoptosis and Autophagy via Reactive Oxygen Species Mediated JNK and P38 Activation in Glioma
inferred← citeshttps://doi.org/10.3389/fcell.2016.00069openalex-snapshot
p38MAPK and Chemotherapy: We Always Need to Hear Both Sides of the Story
inferred← citeshttps://doi.org/10.3389/fonc.2020.571521openalex-snapshot
Mutational Pattern in Multiple Pulmonary Nodules Are Associated With Early Stage Lung Adenocarcinoma
inferred← citeshttps://doi.org/10.3389/fonc.2021.628914openalex-snapshot
Cytotoxic Effects of Arsenite in Combination With Gamabufotalin Against Human Glioblastoma Cell Lines
inferred← citeshttps://doi.org/10.3390/biology14070774openalex-snapshot
HSP70-Mediated Autophagy-Apoptosis-Inflammation Network and Neuroprotection Induced by Heat Acclimatization
inferred← citeshttps://doi.org/10.3390/biom13091354openalex-snapshot
The Effect of SERCA Activation on Functional Characteristics and Signaling of Rat Soleus Muscle upon 7 Days of Unloading
inferred← citeshttps://doi.org/10.3390/cancers12040858openalex-snapshot
Expression of CD44v6-Containing Isoforms Influences Cisplatin Response in Gastric Cancer Cells
inferred← citeshttps://doi.org/10.3390/cancers18020318openalex-snapshot
An Overview of the Mechanisms of HPV-Induced Cervical Cancer: The Role of Kinase Targets in Pathogenesis and Drug Resistance
inferred← citeshttps://doi.org/10.3390/ijms19030767openalex-snapshot
Key Players of Cisplatin Resistance: Towards a Systems Pharmacology Approach
inferred← citeshttps://doi.org/10.3390/ijms19123964openalex-snapshot
A Ruthenium(II) N-Heterocyclic Carbene (NHC) Complex with Naphthalimide Ligand Triggers Apoptosis in Colorectal Cancer Cells via Activating the ROS-p38 MAPK Pathway
inferred← citeshttps://doi.org/10.3390/ijms21061913openalex-snapshot
The p38 Pathway: From Biology to Cancer Therapy
inferred← citeshttps://doi.org/10.3390/ijms22084183openalex-snapshot
Atypical p38 Signaling, Activation, and Implications for Disease
inferred← citeshttps://doi.org/10.3390/ijms23010370openalex-snapshot
The p38 MAPK Components and Modulators as Biomarkers and Molecular Targets in Cancer
inferred← citeshttps://doi.org/10.3390/ijms232012066openalex-snapshot
Diclofenac Sensitizes Signet Ring Cell Gastric Carcinoma Cells to Cisplatin by Activating Autophagy and Inhibition of Survival Signal Pathways
inferred← citeshttps://doi.org/10.3390/ijms24129869openalex-snapshot
Iodine-Biofortified Lettuce Can Promote Mitochondrial Dependent Pathway of Apoptosis in Human Gastrointestinal Cancer Cells
inferred← citeshttps://doi.org/10.3390/ijms25136991openalex-snapshot
The Interplay between the DNA Damage Response (DDR) Network and the Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway in Multiple Myeloma
inferred← citeshttps://doi.org/10.3390/jox16030087openalex-snapshot
Global Geo-Pharmacogenomics: Environmental Mutational Signatures Drive Population-Level Heterogeneity in Anticancer Drug Response
inferred← citeshttps://doi.org/10.3390/md22120564openalex-snapshot
Butyrolactone-I from Marine Fungal Metabolites Mitigates Heat-Stress-Induced Apoptosis in IPEC-J2 Cells and Mice Through the ROS/PERK/CHOP Signaling Pathway
inferred← citeshttps://doi.org/10.3390/ph13120418openalex-snapshot
CDK4/6 and MAPK—Crosstalk as Opportunity for Cancer Treatment
inferred← citeshttps://doi.org/10.34087/cbusbed.1196678openalex-snapshot
Prostat Kanseri Hücrelerinde Kafein Sisplatinin Anti-tümorijenik Etkisini Güçlendirir
inferred← citeshttps://doi.org/10.3748/wjg.v20.i29.9744openalex-snapshot
p38α MAPK pathway: A key factor in colorectal cancer therapy and chemoresistance
inferred← citeshttps://doi.org/10.3748/wjg.v27.i30.4963openalex-snapshot
Stress-activated kinases as therapeutic targets in pancreatic cancer
inferred← citeshttps://doi.org/10.3892/ijmm.2014.1774openalex-snapshot
The combinatory effects of PPAR-γ agonist and survivin inhibition on the cancer stem-like phenotype and cell proliferation in bladder cancer cells
inferred← citeshttps://doi.org/10.3892/ijmm.2015.2225openalex-snapshot
Effect of lentivirus-mediated survivin transfection on the morphology and apoptosis of nucleus pulposus cells derived from degenerative human disc in vitro
inferred← citeshttps://doi.org/10.3892/ijmm.2015.2324openalex-snapshot
Butein sensitizes HeLa cells to cisplatin through the AKT and ERK/p38 MAPK pathways by targeting FoxO3a
inferred← citeshttps://doi.org/10.3892/ijmm.2019.4383openalex-snapshot
Roles of p38α and p38β mitogen‑activated protein kinase isoforms in human malignant melanoma A375 cells
inferred← citeshttps://doi.org/10.3892/ijo.2016.3696openalex-snapshot
Combined oridonin with cetuximab treatment shows synergistic anticancer effects on laryngeal squamous cell carcinoma: Involvement of inhibition of EGFR and activation of reactive oxygen species-mediated JNK pathway
inferred← citeshttps://doi.org/10.3892/ijo.2018.4567openalex-snapshot
Cytocidal effects of arenobufagin and hellebrigenin, two active bufadienolide compounds, against human glioblastoma cell line U-87
inferred← citeshttps://doi.org/10.3892/mmr.2017.7633openalex-snapshot
Baicalin potentiates TRAIL-induced apoptosis through p38 MAPK activation and intracellular reactive oxygen species production
inferred← citeshttps://doi.org/10.3892/mmr.2018.9785openalex-snapshot
Novel 1,4‑naphthoquinone derivatives induce reactive oxygen species‑mediated apoptosis in liver cancer cells
inferred← citeshttps://doi.org/10.3892/mmr.2023.12949openalex-snapshot
RCAS1 increases cell morphological changes in murine fibroblasts by reducing p38 phosphorylation
inferred← citeshttps://doi.org/10.3892/mmr.2024.13330openalex-snapshot
Exploring the therapeutic potential of rabdoternin E in lung cancer treatment: Targeting the ROS/p38 MAPK/JNK signaling pathway
inferred← citeshttps://doi.org/10.3892/ol.2021.12753openalex-snapshot
Silymarin inhibits proliferation of human breast cancer cells via regulation of the MAPK signaling pathway and induction of apoptosis
inferred← citeshttps://doi.org/10.4103/1673-5374.217349openalex-snapshot
Neuroprotective mechanisms of rutin for spinal cord injury through anti-oxidation and anti-inflammation and inhibition of p38 mitogen activated protein kinase pathway
inferred← citeshttps://doi.org/10.4103/jcrt.jcrt_792_22openalex-snapshot
Cisplatin-based combination therapy for cancer
inferred← citeshttps://doi.org/10.4172/2576-1471.1000104openalex-snapshot
Signaling Pathways that Facilitate Chronic Inflammation-Induced Carcinogenesis
inferred← citeshttps://doi.org/10.48048/wjst.2018.3004openalex-snapshot
Reduction of Intracellular-Reactive Oxygen Species and Diminished Mitogen-Activated Protein Kinases (MAPKs) Activation are Associated with Oral Squamous Cell Carcinoma Cell Aggressiveness
inferred← citeshttps://doi.org/10.48130/fia-2023-0028openalex-snapshot
Anti-aging activity and their mechanisms of natural food-derived peptides: current advancements
inferred← citeshttps://doi.org/10.70675/63ceaea1ze673z40c3z9960zed4c40d88ea9openalex-snapshot
Validation de nouvelles cibles thérapeutiques dans le glioblastome par une approche de pharmacologie fonctionnelle
inferred← citeshttps://doi.org/10.70675/ad2bd68az83cdz4738zb39fz6a66ef3080d3openalex-snapshot
Stratégies thérapeutiques compensatoires en cas de perte de fonction du récepteur de peptides formylés 1
inferred← citeshttps://doi.org/10.7314/apjcp.2014.15.20.8539openalex-snapshot
Mitogen-Activated Protein Kinase Signal Transduction in Solid Tumors
inferred← citeshttps://doi.org/10.7554/elife.53367openalex-snapshot
Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma
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