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A Toxicokinetic–Toxicodynamic Modeling Workflow Assessing the Quality of Input Mortality Data

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/etc.120openalex-snapshot
Ecological models and pesticide risk assessment: Current modeling practice
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Development and Validation of a Mixture Toxicity Implementation in the Dynamic Energy Budget–Individual-Based Model: Effects of Copper and Zinc on Daphnia magna Populations
inferredcites →https://doi.org/10.1002/etc.5027openalex-snapshot
Disentangling Mechanisms Behind Chronic Lethality through Toxicokinetic–Toxicodynamic Modeling
inferredcites →https://doi.org/10.1002/etc.5176openalex-snapshot
Interactive Metal Mixture Toxicity to Daphnia magna Populations as an Emergent Property in a Dynamic Energy Budget Individual-Based Model
inferredcites →https://doi.org/10.1002/etc.5348openalex-snapshot
Fish Species Sensitivity Ranking Depends on Pesticide Exposure Profiles
inferredcites →https://doi.org/10.1007/978-3-319-24277-4openalex-snapshot
ggplot2
inferredcites →https://doi.org/10.1007/s00244-022-00963-2openalex-snapshot
Physiological Dependency Explains Temperature Differences in Sensitivity Towards Chemical Exposure
inferredcites →https://doi.org/10.1007/s10646-012-0917-0openalex-snapshot
Toxicokinetic-toxicodynamic modelling of survival of Gammarus pulex in multiple pulse exposures to propiconazole: model assumptions, calibration data requirements and predictive power
inferredcites →https://doi.org/10.1007/s10646-013-1149-7openalex-snapshot
Reconsidering sufficient and optimal test design in acute toxicity testing
inferredcites →https://doi.org/10.1007/s10646-018-1940-6openalex-snapshot
Calibration and validation of toxicokinetic-toxicodynamic models for three neonicotinoids and some aquatic macroinvertebrates
inferredcites →https://doi.org/10.1007/s11356-019-04423-8openalex-snapshot
Exploring inter-species sensitivity to a model hydrocarbon, 2-Methylnaphtalene, using a process-based model
inferredcites →https://doi.org/10.1007/s11356-022-19111-3openalex-snapshot
A critical review of effect modeling for ecological risk assessment of plant protection products
inferredcites →https://doi.org/10.1016/j.ecolmodel.2019.108784openalex-snapshot
How to make ecological models useful for environmental management
inferredcites →https://doi.org/10.1016/j.envpol.2015.07.045openalex-snapshot
Body size-dependent toxicokinetics and toxicodynamics could explain intra- and interspecies variability in sensitivity
inferredcites →https://doi.org/10.1016/j.envsoft.2020.104932openalex-snapshot
Keeping modelling notebooks with TRACE: Good for you and good for environmental research and management support
inferredcites →https://doi.org/10.1016/j.jspi.2011.07.014openalex-snapshot
Bayesian experimental design for a toxicokinetic–toxicodynamic model
inferredcites →https://doi.org/10.1016/j.scitotenv.2022.157048openalex-snapshot
How to analyse and account for interactions in mixture toxicity with toxicokinetic-toxicodynamic models
inferredcites →https://doi.org/10.1016/j.scitotenv.2022.158886openalex-snapshot
The effect of temperature on toxicokinetics and the chronic toxicity of insecticides towards Gammarus pulex
inferredcites →https://doi.org/10.1016/j.scitotenv.2022.159266openalex-snapshot
Joint survival modelling for multiple species exposed to toxicants
inferredcites →https://doi.org/10.1021/acs.est.2c04085openalex-snapshot
Explicit Consideration of Temperature Improves Predictions of Toxicokinetic–Toxicodynamic Models for Flupyradifurone and Imidacloprid in Gammarus pulex
inferredcites →https://doi.org/10.1021/acs.est.9b01690openalex-snapshot
Mechanistic Effect Modeling Approach for the Extrapolation of Species Sensitivity
inferredcites →https://doi.org/10.1021/es103092aopenalex-snapshot
General Unified Threshold Model of Survival - a Toxicokinetic-Toxicodynamic Framework for Ecotoxicology
inferredcites →https://doi.org/10.1021/es801418xopenalex-snapshot
A Bayesian Approach to Analyzing Ecotoxicological Data
inferredcites →https://doi.org/10.1038/srep29178openalex-snapshot
Modelling survival: exposure pattern, species sensitivity and uncertainty
inferredcites →https://doi.org/10.1039/c0em00234hopenalex-snapshot
Advantages of toxicokinetic and toxicodynamic modelling in aquatic ecotoxicology and risk assessment
inferredcites →https://doi.org/10.1080/10807039.2011.552391openalex-snapshot
Adding Value to Ecological Risk Assessment with Population Modeling
inferredcites →https://doi.org/10.1111/gcb.16438openalex-snapshot
Three perspectives on the prediction of chemical effects in ecosystems
inferredcites →https://doi.org/10.1111/j.1539-6924.2012.01835.xopenalex-snapshot
Stakeholders’ Perspective on Ecological Modeling in Environmental Risk Assessment of Pesticides: Challenges and Opportunities
inferredcites →https://doi.org/10.1201/9781439813492openalex-snapshot
Linking Aquatic Exposure and Effects: Risk Assessment of Pesticides
inferredcites →https://doi.org/10.21105/joss.01686openalex-snapshot
Welcome to the Tidyverse
inferredcites →https://doi.org/10.21105/joss.03200openalex-snapshot
morse: an R-package to analyse toxicity test data
inferredcites →https://doi.org/10.2903/j.efsa.2018.5377openalex-snapshot
Scientific Opinion on the state of the art of Toxicokinetic/Toxicodynamic (TKTD) effect models for regulatory risk assessment of pesticides for aquatic organisms
inferredcites →https://doi.org/10.32614/r.manualsopenalex-snapshot
R: A Language and Environment for Statistical Computing

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4872917openalex-extracted
Guts-Immobility: Accounting for Resuscitating Individuals in Aquatic Survival Studies within the General Unified Threshold Model for Survival
inferred← citeshttps://doi.org/10.1002/etc.5833openalex-snapshot
Identifying and Predicting Delayed Mortality with Toxicokinetic–Toxicodynamic Models
inferred← citeshttps://doi.org/10.1016/j.ecolmodel.2024.111016openalex-snapshot
Global sensitivity analysis of the harmonized Lemna model
inferred← citeshttps://doi.org/10.1016/j.tiv.2026.106244openalex-snapshot
Sublethal concentrations of PFOS and PFDA differentially impact brood size and gene expression in Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1021/acs.est.4c03056openalex-snapshot
Correspondence on “Mortality Pattern of Poecilus cupreus Beetles after Repeated Topical Exposure to Insecticide─Stochastic Death or Individual Tolerance?”
inferred← citeshttps://doi.org/10.1021/acs.est.5c03925openalex-snapshot
Combined Modeling of Multiple Exposure Routes for Terrestrial Arthropods Using the Toxicokinetic–Toxicodynamic BufferGUTS Model
inferred← citeshttps://doi.org/10.2139/ssrn.6300521openalex-snapshot
Effects of the Polycyclic Aromatic Hydrocarbon Anthracene on the Survival of the Semi-Aquatic Grasshopper Cornops aquaticum (Bruner, 1906): An Experimental Toxicological Study
inferred← citeshttps://doi.org/10.3389/fenvs.2026.1817685openalex-snapshot
Effects of the polycyclic aromatic hydrocarbon anthracene on the survival of the semi-aquatic grasshopper Cornops aquaticum (Bruner, 1906): an experimental toxicological study
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